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691961Publicado 2021“…We studied the factors (ie, human and facility resources, patient comorbidities, and critical care interventions) that were associated with mortality in these adult patients. …”
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691962por Bustamante-Andrade, Jorge A., Meza-Herrera, César A., Rodríguez-Martínez, Rafael, Santos-Jimenez, Zurisaday, Ángel-García, Oscar, Gaytán-Alemán, Leticia R., Gutierrez-Guzman, Ulises N., Esquivel-Romo, Amaury, Véliz-Deras, Francisco G.“…In order to abolish or reduce this reproductive seasonality, exogenous hormones, such as human chorionic gonadotropin (hCG), have been used to stimulate the development of ovarian follicles, triggering ovulation, corpus luteum formation, while increasing serum progesterone levels, fetal growth, prolificacy, and kidding rate. …”
Publicado 2021
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691963por Ross, Elizabeth G, Ball, Jase J, Werth, Samantha J, Mejia-Turcios, Sebastian E, Zhao, Yongjing, Pan, Yuee, Taube, Patrick C, Meinert, Todd R, Van Engen, Nicholas K, Mitloehner, F M“…With a growing global population and increased environmental concerns around animal agriculture, it is essential to humanely maximize animal performance and reduce environmental emissions. …”
Publicado 2021
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691964por Crous, P.W., Hernández-Restrepo, M., Schumacher, R.K., Cowan, D.A., Maggs-Kölling, G., Marais, E., Wingfield, M.J., Yilmaz, N., Adan, O.C.G., Akulov, A., Duarte, E. Álvarez, Berraf-Tebbal, A., Bulgakov, T.S., Carnegie, A.J., de Beer, Z.W., Decock, C., Dijksterhuis, J., Duong, T.A., Eichmeier, A., Hien, L.T., Houbraken, J.A.M.P., Khanh, T.N., Liem, N.V., Lombard, L., Lutzoni, F.M., Miadlikowska, J.M., Nel, W.J., Pascoe, I.G., Roets, F., Roux, J., Samson, R.A., Shen, M., Spetik, M., Thangavel, R., Thanh, H.M., Thao, L.D., van Nieuwenhuijzen, E.J., Zhang, J.Q., Zhang, Y., Zhao, L.L., Groenewald, J.Z.“…(Angola); Niesslia neoexosporioides on dead leaves of Carex paniculata (Germany); Nothoanungitopsis urophyllae on seed capsules of Eucalyptus urophylla (South Africa); Nothomicrosphaeropsis welwitschiae on dead leaves of Welwitschia mirabilis (Namibia); Paracremonium bendijkiorum from soil (Netherlands); Paraphoma ledniceana on dead wood of Buxus sempervirens (Czech Republic); Paraphoma salicis on leaves of Salix cf. alba (Ukraine); Parasarocladium wereldwijsianum from soil (Netherlands); Peziza ligni on masonry and plastering (France); Phyllosticta phoenicis on leaves of Phoenix reclinata (South Africa); Plectosphaerella slobbergiarum from soil (Netherlands); Populomyces zwinianus from soil (Netherlands); Pseudoacrospermum goniomae on leaves of Gonioma kamassi (South Africa); Pseudopyricularia festucae on leaves of Festuca californica (USA); Sarocladium sasijaorum from soil (Netherlands); Sporothrix hypoxyli in sporocarp of Hypoxylon petriniae on Fraxinus wood (Netherlands); Superstratomyces albomucosus on Pycnanthus angolensis (Netherlands); Superstratomyces atroviridis on Pinus sylvestris (Netherlands); Superstratomyces flavomucosus on leaf of Hakea multilinearis (Australia); Superstratomyces tardicrescens from human eye specimen (USA); Taeniolella platani on twig of Platanus hispanica (Germany), and Tympanis pini on twigs of Pinus sylvestris (Spain). …”
Publicado 2021
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691965por Lorenzo, Petra I., Martin Vazquez, Eugenia, López-Noriega, Livia, Fuente-Martín, Esther, Mellado-Gil, José M., Franco, Jaime M., Cobo-Vuilleumier, Nadia, Guerrero Martínez, José A., Romero-Zerbo, Silvana Y., Perez-Cabello, Jesús A., Rivero Canalejo, Sabrina, Campos-Caro, Antonio, Lachaud, Christian Claude, Crespo Barreda, Alejandra, Aguilar-Diosdado, Manuel, García Fuentes, Eduardo, Martin-Montalvo, Alejandro, Álvarez Dolado, Manuel, Martin, Franz, Rojo-Martinez, Gemma, Pozo, David, Bérmudez-Silva, Francisco J., Comaills, Valentine, Reyes, José C., Gauthier, Benoit R.“…Methods: HMG20A expression profile was assessed by quantitative PCR (QT-PCR), Western blotting and/or immunofluorescence in: 1) the hypothalamus of mice exposed or not to either a high-fat diet or a high-fat high-sucrose regimen, 2) human blood leukocytes and adipose tissue obtained from healthy or diabetic individuals and 3) primary mouse hypothalamic astrocytes exposed to either high glucose or palmitate. …”
Publicado 2021
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691966por Belay, Mulugeta, Tulu, Begna, Younis, Sidra, Jolliffe, David A, Tayachew, Dawit, Manwandu, Hana, Abozen, Tenagnework, Tirfie, Emawayish A, Tegegn, Metasebia, Zewude, Aboma, Forrest, Sally, Mayito, Jonathan, Huggett, Jim F, Jones, Gerwyn M, O'Sullivan, Denise M, Martineau, Henny M, Noursadeghi, Mahdad, Chandran, Aneesh, Harris, Kathryn A, Nikolayevskyy, Vlad, Demaret, Julie, Berg, Stefan, Vordermeier, Martin, Balcha, Taye T, Aseffa, Abraham, Ameni, Gobena, Abebe, Markos, Reece, Stephen T, Martineau, Adrian R“…Digital PCR (dPCR) was used to determine whether M tuberculosis complex DNA was detectable in PBMCs isolated from 100 mL blood taken from asymptomatic adults with HIV infection or a history of recent household or occupational exposure to an index case of human or bovine tuberculosis. Participants were recruited from HIV clinics, tuberculosis clinics, and cattle farms in and around Addis Ababa. …”
Publicado 2021
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691967por Kahnbach, Leonie, Lehr, Dirk, Brandenburger, Jessica, Mallwitz, Tim, Jent, Sophie, Hannibal, Sandy, Funk, Burkhardt, Janneck, Monique“…An interdisciplinary team, consisting of two health and two human–computer interaction scientists, independently conducted Mobile App Rating Scale ratings. …”
Publicado 2021
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691968por Feng, Felix Y., Thomas, Shibu, Saad, Fred, Gormley, Michael, Yu, Margaret K., Ricci, Deborah S., Rooney, Brendan, Brookman-May, Sabine, McCarthy, Sharon, Olmos, David, Chowdhury, Simon, Hadaschik, Boris, Liu, Yang, Davicioni, Elai, Smith, Matthew R., Small, Eric J.“…DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, gene expression data from 233 archived samples from patients with nmCRPC enrolled in the SPARTAN trial were generated using a human exon microarray. The present analysis was conducted from May 10, 2018, to October 15, 2020. …”
Publicado 2021
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691969por Jan, Hasnain, Usman, Hazrat, Shah, Muzamil, Zaman, Gouhar, Mushtaq, Sadaf, Drouet, Samantha, Hano, Christophe, Abbasi, Bilal Haider“…Ex Royle) is a medicinal plant and have been used as traditional treatments for various human diseases including skin burns, jaundice, hepatitis, wound healing, cardiovascular and circulatory diseases. …”
Publicado 2021
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691970“…BACKGROUND: People living with human immunodeficiency virus (HIV) with immuno-virological discordant responses are at an increased risk to develop acquired immunodeficiency syndrome (AIDS) and severe non AIDS events which are risk factors for death. …”
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691971por Guijarro, Luis G., Sanmartin-Salinas, Patricia, Pérez-Cuevas, Eva, Toledo-Lobo, M. Val, Monserrat, Jorge, Zoullas, Sofía, Sáez, Miguel A., Álvarez-Mon, Miguel A., Bujan, Julia, Noguerales-Fraguas, Fernando, Arilla-Ferreiro, Eduardo, Álvarez-Mon, Melchor, Ortega, Miguel A.“…Immunoblot analyses showed that IRS-4 in normal human liver biopsies was lower than in HepG2, Huh7, and Chang cells. …”
Publicado 2021
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691972por Tontini, Gian Eugenio, Rimondi, Alessandro, Vernero, Marta, Neumann, Helmut, Vecchi, Maurizio, Bezzio, Cristina, Cavallaro, Flaminia“…METHODS: A systematic search was carried out in PubMed and Scopus up to 2 December 2020 using the following search terms: artificial intelligence, machine learning, computer-aided, inflammatory bowel disease, ulcerative colitis (UC), Crohn’s disease (CD). All studies on human digestive endoscopy were included. A qualitative analysis and a narrative description were performed for each selected record according to the Joanna Briggs Institute methodologies and the PRISMA statement. …”
Publicado 2021
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691973por Teixeira, Liliane R., Pega, Frank, de Abreu, Wagner, de Almeida, Marcia S., de Andrade, Carlos A.F., Azevedo, Tatiana M., Dzhambov, Angel M., Hu, Weijiang, Macedo, Marta R.V., Martínez-Silveira, Martha S., Sun, Xin, Zhang, Meibian, Zhang, Siyu, Correa da Silva, Denise T.“…Evidence from mechanistic and human data suggests that occupational exposure to noise may cause cardiovascular disease. …”
Publicado 2021
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691974por Haderbache, Rafik, Warda, Walid, Hervouet, Eric, da Rocha, Mathieu Neto, Trad, Rim, Allain, Vincent, Nicod, Clementine, Thieblemeont, Catherine, Boissel, Nicolas, Varlet, Pauline, Agha, Ibrahim Yakoub, Bouquet, Lucie, Guiot, Melanie, Venet, Fabienne, Sujobert, Pierre, Roussel, Xavier, Rouzaire, Paul-Oliver, Caillot, Denis, Casasnovas, Olivier, Bories, Jean Christophe, Bachy, Emmanuel, Caillat-Zucman, Sophie, Deschamps, Marina, Ferrand, Christophe“…RESULTS: 28BBz and 28z ddPCR assays applied to 2 tumoral (acute myeloid leukemia (AML) or multiple myeloma (MM) xenograft humanized NSG mouse models allowed us to quantify the early expansion (up to day 30) of CAR T cells after injection. …”
Publicado 2021
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691975por Li, Jian, Deng, Yanhong, Zhang, Weijie, Zhou, Ai-Ping, Guo, Weijian, Yang, Jianwei, Yuan, Ying, Zhu, Liangjun, Qin, Shukui, Xiang, Silong, Lu, Haolan, Gong, John, Xu, Ting, Liu, David, Shen, Lin“…BACKGROUND: Monoclonal antibodies targeting programmed death ligand 1 (PD-L1) signaling currently approved for defective mismatch repair (dMMR)/microsatellite instability high (MSI-H) tumors must be delivered by intravenous infusion. Envafolimab, a humanized single-domain anti-PD-L1 antibody fused to an Fc fragment, represents a potential advance because it can be conveniently administered subcutaneously. …”
Publicado 2021
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691976por Sadoff, Jerald, Gray, Glenda, Vandebosch, An, Cárdenas, Vicky, Shukarev, Georgi, Grinsztejn, Beatriz, Goepfert, Paul A., Truyers, Carla, Fennema, Hein, Spiessens, Bart, Offergeld, Kim, Scheper, Gert, Taylor, Kimberly L., Robb, Merlin L., Treanor, John, Barouch, Dan H., Stoddard, Jeffrey, Ryser, Martin F., Marovich, Mary A., Neuzil, Kathleen M., Corey, Lawrence, Cauwenberghs, Nancy, Tanner, Tamzin, Hardt, Karin, Ruiz-Guiñazú, Javier, Le Gars, Mathieu, Schuitemaker, Hanneke, Van Hoof, Johan, Struyf, Frank, Douoguih, Macaya“…BACKGROUND: The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation. …”
Publicado 2021
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691977Transcriptomic and Genetic Associations between Alzheimer’s Disease, Parkinson’s Disease, and Cancerpor Forés-Martos, Jaume, Boullosa, Cesar, Rodrigo-Domínguez, David, Sánchez-Valle, Jon, Suay-García, Beatriz, Climent, Joan, Falcó, Antonio, Valencia, Alfonso, Puig-Butillé, Joan Anton, Puig, Susana, Tabarés-Seisdedos, Rafael“…ABSTRACT: Alzheimer’s (AD) and Parkinson’s diseases (PD) are the two most prevalent neurodegenerative disorders in human populations. Epidemiological studies have shown that patients suffering from either condition present a reduced overall risk of cancer than controls (i.e., inverse comorbidity), suggesting that neurodegeneration provides a protective effect against cancer. …”
Publicado 2021
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691978por Ben-Yehuda, Hila, Arad, Michal, Peralta Ramos, Javier María, Sharon, Efrat, Castellani, Giulia, Ferrera, Shir, Cahalon, Liora, Colaiuta, Sarah Phoebeluc, Salame, Tomer-Meir, Schwartz, Michal“…This was accompanied by the loss of the beneficial effect on disease pathology, assessed by measurement of cortical aggregated human tau load using Homogeneous Time Resolved Fluorescence-based immunoassay, and by evaluation of hippocampal neuronal survival. …”
Publicado 2021
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691979
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691980por Brook, M.S., Scaife, P., Bass, J.J., Cegielski, J., Watanabe, S., Wilkinson, D.J., Smith, K., Phillips, B.E., Atherton, P.J.“…Yet the acute effects of collagen protein blended with other protein sources, in relation to skeletal muscle anabolism, are ill-defined. We investigated human muscle protein synthesis (MPS) responses to a 20 g blend of collagen protein hydrolysate + milk protein (CP+MP, 125 ml) oral nutritional supplement (ONS) vs. 20 g non-blended milk protein source (MP, 200 ml) ONS, in older adults. …”
Publicado 2021
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