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692041por Huang, Wen-Chien, Yadav, Vijesh Kumar, Cheng, Wei-Hong, Wang, Chun-Hua, Hsieh, Ming-Shou, Huang, Ting-Yi, Lin, Shiou-Fu, Yeh, Chi-Tai, Kuo, Kuang-Tai“…Osimertinib-sensitive and resistant NSCLC cells obtained from patients were used to co-culture with human lung fibroblasts (HLFs) to generate CAF cells (termed CAF_R1 and CAF_S1), and the functional roles of these CAF cells plus the regulatory mechanisms were further explored. …”
Publicado 2021
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692042por Mahani, Amir, Arvidsson, Gustav, Sadeghi, Laia, Grandien, Alf, Wright, Anthony P. H.“…ABSTRACT: The MYC transcription factor regulates a vast number of genes and is implicated in many human malignancies. In some hematological malignancies, MYC is frequently subject to missense mutations that enhance its transformation activity. …”
Publicado 2021
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692043por Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Matsunaga, Atsuko, Fang, Xuexiu, Pacholczyk, Rafal, Zhou, Gang, Cowell, John K., Hu, Tianxiang“…Mouse models have been developed which faithfully recapitulate the human disease and have been used to characterize the molecular genetic events that are associated with development and progression of the disease. …”
Publicado 2021
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692044“…BACKGROUND: Cellular miRNAs are expressed in tissue fluids with sufficient amounts and were identified as potential molecular targets for studying the physiological mechanisms and correlations with many human diseases particularly diabetes. However, molecular-based changes among older adults with diabetes mellitus (DM) are rarely fully elucidated. …”
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692045por Haukvik, Unn K., Gurholt, Tiril P., Nerland, Stener, Elvsåshagen, Torbjørn, Akudjedu, Theophilus N., Alda, Martin, Alnæs, Dag, Alonso‐Lana, Silvia, Bauer, Jochen, Baune, Bernhard T., Benedetti, Francesco, Berk, Michael, Bettella, Francesco, Bøen, Erlend, Bonnín, Caterina M., Brambilla, Paolo, Canales‐Rodríguez, Erick J., Cannon, Dara M., Caseras, Xavier, Dandash, Orwa, Dannlowski, Udo, Delvecchio, Giuseppe, Díaz‐Zuluaga, Ana M., van Erp, Theo G. M., Fatjó‐Vilas, Mar, Foley, Sonya F., Förster, Katharina, Fullerton, Janice M., Goikolea, José M., Grotegerd, Dominik, Gruber, Oliver, Haarman, Bartholomeus C. M., Haatveit, Beathe, Hajek, Tomas, Hallahan, Brian, Harris, Mathew, Hawkins, Emma L., Howells, Fleur M., Hülsmann, Carina, Jahanshad, Neda, Jørgensen, Kjetil N., Kircher, Tilo, Krämer, Bernd, Krug, Axel, Kuplicki, Rayus, Lagerberg, Trine V., Lancaster, Thomas M., Lenroot, Rhoshel K., Lonning, Vera, López‐Jaramillo, Carlos, Malt, Ulrik F., McDonald, Colm, McIntosh, Andrew M., McPhilemy, Genevieve, van der Meer, Dennis, Melle, Ingrid, Melloni, Elisa M. T., Mitchell, Philip B., Nabulsi, Leila, Nenadić, Igor, Oertel, Viola, Oldani, Lucio, Opel, Nils, Otaduy, Maria C. G., Overs, Bronwyn J., Pineda‐Zapata, Julian A., Pomarol‐Clotet, Edith, Radua, Joaquim, Rauer, Lisa, Redlich, Ronny, Repple, Jonathan, Rive, Maria M., Roberts, Gloria, Ruhe, Henricus G., Salminen, Lauren E., Salvador, Raymond, Sarró, Salvador, Savitz, Jonathan, Schene, Aart H., Sim, Kang, Soeiro‐de‐Souza, Marcio G., Stäblein, Michael, Stein, Dan J., Stein, Frederike, Tamnes, Christian K., Temmingh, Henk S., Thomopoulos, Sophia I., Veltman, Dick J., Vieta, Eduard, Waltemate, Lena, Westlye, Lars T., Whalley, Heather C., Sämann, Philipp G., Thompson, Paul M., Ching, Christopher R. K., Andreassen, Ole A., Agartz, IngridEnlace del recurso
Publicado 2020
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692046por de Zwarte, Sonja M. C., Brouwer, Rachel M., Agartz, Ingrid, Alda, Martin, Alonso‐Lana, Silvia, Bearden, Carrie E., Bertolino, Alessandro, Bonvino, Aurora, Bramon, Elvira, Buimer, Elizabeth E. L., Cahn, Wiepke, Canales‐Rodríguez, Erick J., Cannon, Dara M., Cannon, Tyrone D., Caseras, Xavier, Castro‐Fornieles, Josefina, Chen, Qiang, Chung, Yoonho, De la Serna, Elena, del Mar Bonnin, Caterina, Demro, Caroline, Di Giorgio, Annabella, Doucet, Gaelle E., Eker, Mehmet Cagdas, Erk, Susanne, Fatjó‐Vilas, Mar, Fears, Scott C., Foley, Sonya F., Frangou, Sophia, Fullerton, Janice M., Glahn, David C., Goghari, Vina M., Goikolea, Jose M., Goldman, Aaron L., Gonul, Ali Saffet, Gruber, Oliver, Hajek, Tomas, Hawkins, Emma L., Heinz, Andreas, Hidiroglu Ongun, Ceren, Hillegers, Manon H. J., Houenou, Josselin, Hulshoff Pol, Hilleke E., Hultman, Christina M., Ingvar, Martin, Johansson, Viktoria, Jönsson, Erik G., Kane, Fergus, Kempton, Matthew J., Koenis, Marinka M. G., Kopecek, Miloslav, Krämer, Bernd, Lawrie, Stephen M., Lenroot, Rhoshel K., Marcelis, Machteld, Mattay, Venkata S., McDonald, Colm, Meyer‐Lindenberg, Andreas, Michielse, Stijn, Mitchell, Philip B., Moreno, Dolores, Murray, Robin M., Mwangi, Benson, Nabulsi, Leila, Newport, Jason, Olman, Cheryl A., van Os, Jim, Overs, Bronwyn J., Ozerdem, Aysegul, Pergola, Giulio, Picchioni, Marco M., Piguet, Camille, Pomarol‐Clotet, Edith, Radua, Joaquim, Ramsay, Ian S., Richter, Anja, Roberts, Gloria, Salvador, Raymond, Saricicek Aydogan, Aybala, Sarró, Salvador, Schofield, Peter R., Simsek, Esma M., Simsek, Fatma, Soares, Jair C., Sponheim, Scott R., Sugranyes, Gisela, Toulopoulou, Timothea, Tronchin, Giulia, Vieta, Eduard, Walter, Henrik, Weinberger, Daniel R., Whalley, Heather C., Wu, Mon‐Ju, Yalin, Nefize, Andreassen, Ole A., Ching, Christopher R. K., Thomopoulos, Sophia I., van Erp, Theo G. M., Jahanshad, Neda, Thompson, Paul M., Kahn, René S., van Haren, Neeltje E. M.Enlace del recurso
Publicado 2020
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692047por Ching, Christopher R. K., Hibar, Derrek P., Gurholt, Tiril P., Nunes, Abraham, Thomopoulos, Sophia I., Abé, Christoph, Agartz, Ingrid, Brouwer, Rachel M., Cannon, Dara M., de Zwarte, Sonja M. C., Eyler, Lisa T., Favre, Pauline, Hajek, Tomas, Haukvik, Unn K., Houenou, Josselin, Landén, Mikael, Lett, Tristram A., McDonald, Colm, Nabulsi, Leila, Patel, Yash, Pauling, Melissa E., Paus, Tomas, Radua, Joaquim, Soeiro‐de‐Souza, Marcio G., Tronchin, Giulia, van Haren, Neeltje E. M., Vieta, Eduard, Walter, Henrik, Zeng, Ling‐Li, Alda, Martin, Almeida, Jorge, Alnæs, Dag, Alonso‐Lana, Silvia, Altimus, Cara, Bauer, Michael, Baune, Bernhard T., Bearden, Carrie E., Bellani, Marcella, Benedetti, Francesco, Berk, Michael, Bilderbeck, Amy C., Blumberg, Hilary P., Bøen, Erlend, Bollettini, Irene, del Mar Bonnin, Caterina, Brambilla, Paolo, Canales‐Rodríguez, Erick J., Caseras, Xavier, Dandash, Orwa, Dannlowski, Udo, Delvecchio, Giuseppe, Díaz‐Zuluaga, Ana M., Dima, Danai, Duchesnay, Édouard, Elvsåshagen, Torbjørn, Fears, Scott C., Frangou, Sophia, Fullerton, Janice M., Glahn, David C., Goikolea, Jose M., Green, Melissa J., Grotegerd, Dominik, Gruber, Oliver, Haarman, Bartholomeus C. M., Henry, Chantal, Howells, Fleur M., Ives‐Deliperi, Victoria, Jansen, Andreas, Kircher, Tilo T. J., Knöchel, Christian, Kramer, Bernd, Lafer, Beny, López‐Jaramillo, Carlos, Machado‐Vieira, Rodrigo, MacIntosh, Bradley J., Melloni, Elisa M. T., Mitchell, Philip B., Nenadic, Igor, Nery, Fabiano, Nugent, Allison C., Oertel, Viola, Ophoff, Roel A., Ota, Miho, Overs, Bronwyn J., Pham, Daniel L., Phillips, Mary L., Pineda‐Zapata, Julian A., Poletti, Sara, Polosan, Mircea, Pomarol‐Clotet, Edith, Pouchon, Arnaud, Quidé, Yann, Rive, Maria M., Roberts, Gloria, Ruhe, Henricus G., Salvador, Raymond, Sarró, Salvador, Satterthwaite, Theodore D., Schene, Aart H., Sim, Kang, Soares, Jair C., Stäblein, Michael, Stein, Dan J., Tamnes, Christian K., Thomaidis, Georgios V., Upegui, Cristian Vargas, Veltman, Dick J., Wessa, Michèle, Westlye, Lars T., Whalley, Heather C., Wolf, Daniel H., Wu, Mon‐Ju, Yatham, Lakshmi N., Zarate, Carlos A., Thompson, Paul M., Andreassen, Ole A.Enlace del recurso
Publicado 2020
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692048“…AIM: To investigate early CPR effects on human myeloperoxidase (MPO), soluble ST2 (sST2), and hypersensitive C-reactive protein (hs-CRP) levels in AMI patients. …”
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692049por Schroeder, Courtney, Hachem, Hilal, Godara, Amandeep, Fein, Daniel, Mann, Hashim, Lawlor, Christian, Marshall, Jill, Klein, Andreas, Poutsiaka, Debra, Breeze, Janis, Joshi, Raghav, Mathew, Paul“…Secondary endpoints included 28-day mortality, dynamic cytokine profiles (Human Cytokine 48-Plex Discovery Assay), secondary infections, duration of supplemental oxygen support and hospitalization. …”
Publicado 2021
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692050por Paguntalan, Helen, Magyarics, Zoltán, Connolly, Lynn E, Hershberger, Ellie, Narayan, Kristin, Gupta, Deepali, Ambrose, Paul G, Engler, Frank, Campanaro, Ed, Das, Anita F, Schmidt, Pete“…BACKGROUND: ADG20 is a fully human IgG1 monoclonal antibody engineered to have high potency and broad neutralization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other SARS-like CoVs with pandemic potential by binding to a highly conserved epitope in the receptor-binding domain (RBD) of the spike protein. …”
Publicado 2021
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692051“…Treatment for CC is out of reach for many women, hence the need to maximise on prevention which mainly includes screening and administering human papillomavirus (HPV) vaccine. Knowledge about CC prevention is a prerequisite for utilisation of all the available options for CC prevention, yet little is known about its levels and the corresponding attitudes and practices on cancer prevention methods within the society. …”
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692052“…Our primary objective was to quantify stress relaxation of the hindfoot bones when subjected to a fixed compression displacement as would be done during arthrodesis. METHODS: 10 human cadaveric bone cylinders measuring 10 mm in both diameter and height were cut from the articular surfaces of the talus, calcaneus, and distal tibia using a disposable cylindrical osteochondral harvester (OATS, Arthrex inc, Naples, FL). …”
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692053por Appiah, Francis, Fenteng, Justice Ofosu Darko, Dare, Felix, Salihu, Tarif, Darteh, Andrews Ohene, Takyi, Matthew, Ayerakwah, Patience Ansomah, Ameyaw, Edward Kwabena“…Utilising the Bronfenbrenner’s Ecological Model of Human Development, the study aimed at assessing determinants of PNC utilisation for babies by their mothers aged 15–49 in PNG. …”
Publicado 2021
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692054por Skrzypczak, Wiesław, Dratwa-Chałupnik, Alicja, Ożgo, Małgorzata, Boniecka, Karolina“…Newborn calves show high somatic maturity compared to, for example, human newborns, but their body functions with a lower efficiency than that of adult cattle. …”
Publicado 2021
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692055por Boukrout, Nihad, Souidi, Mouloud, Lahdaoui, Fatima, Duchêne, Belinda, Neve, Bernadette, Coppin, Lucie, Leteurtre, Emmanuelle, Torrisani, Jérôme, Van Seuningen, Isabelle, Jonckheere, Nicolas“…Results: miR-210-3p expression is correlated with MUC4 expression in PDAC-derived cells and human samples, and in pancreatic PanIN lesions of Pdx1-Cre; LstopL-KrasG12D mice. …”
Publicado 2021
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692056por Sabaie, Hani, Moghaddam, Madiheh Mazaheri, Moghaddam, Marziyeh Mazaheri, Ahangar, Noora Karim, Asadi, Mohammad Reza, Hussen, Bashdar Mahmud, Taheri, Mohammad, Rezazadeh, Maryam“…Differentially expressed mRNAs (DEmRNAs) and lncRNAs (DElncRNAs) were identified using the limma package of the R software. Using DIANA-LncBase, Human MicroRNA Disease Database (HMDD), and miRTarBase, the lncRNA- associated ceRNA network was generated. …”
Publicado 2021
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692057por Malli, Foteini, Lampropoulos, Ioannis C, Iatrou, Giorgos, Kotsiou, Ourania S, Bardaka, Fotini, Kotrotsiou, Evangelia, Fradelos, Evangelos C, Gourgoulianis, Konstantinos, Daniil, Zoe“…SCS Self-kindness score correlated significantly with total HFS score (p=0.002, r=0.613), forgiveness of self (p=0.011, r=0.528), forgiveness of others (p=0.008, r=0.550), and forgiveness of situations (p=0.004. r=0.587). Common humanity was significantly correlated with total HFS score (p=0.023, r=0.481), forgiveness of others (p=0.033, r=0.456), and forgiveness of situations (p=0.016, r=0.507). …”
Publicado 2021
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692058por Dinsmore, John, Hannigan, Caoimhe, Smith, Suzanne, Murphy, Emma, Kuiper, Janneke M L, O'Byrne, Emma, Galvin, Mary, Jacobs, An, Sillevis Smitt, Myriam, van Leeuwen, Cora, McAleer, Patricia, Tompkins, Lorraine, Brady, Anne-Marie, McCarron, Mary, Doyle, Julie“…CONCLUSIONS: ProACT aims to co-design and develop a digital intervention with persons with multimorbidities and their CN, incorporating clinical guidelines with the state of the art in human-computer interaction, behavioral science, health psychology, and data analytic methods to deliver a digital health platform to advance self-management of multimorbidity at home, as part of a proactive, integrated model of supported person-centered care. …”
Publicado 2021
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692059por Bussmann, Rainer W., Paniagua Zambrana, Narel Y., Ur Rahman, Inayat, Kikvidze, Zaal, Sikharulidze, Shalva, Kikodze, David, Tchelidze, David, Khutsishvili, Manana, Batsatsashvili, Ketevan“…BACKGROUND: The Republic of Georgia is part of the Caucasus biodiversity hotspot, and human agricultural plant use dates back at least 6000 years. …”
Publicado 2021
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692060“…Cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) were assessed using enzyme-linked immunosorbent assay (ELISA). …”
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