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  1. 692321
    “…Unbound zinc levels were measured in human and infected mice plasma. MEM MICs were determined in Mueller Hinton Broth (MHB) and MHB adjusted to the physiologic zinc levels. …”
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    1650. Efficacy of β-Lactam Therapy against Infections Caused by Metallo-β-lactamase (MBL)-Producing Enterobacterales: Bridging the Susceptibility Testing Gap
  2. 692322
    “…BACKGROUND: CRE isolates are considered a threat to human health. Until recently, the treatment options for CRE were limited. …”
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    664. Increase in the Occurrence of Carbapenem-Resistant Enterobacterales (CRE) in United States (US) Hospitals from 2019 to 2021 and Activity of Novel b-Lactam/b-Lactamase Inhibitor (BL/BLI) Combinations Against These Isolates
  3. 692323
    “…BACKGROUND: Antiretroviral therapy (ART) for the human immunodeficiency virus (HIV) has improved life expectancy in people living with HIV/AIDS (PLWHA). …”
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    1256. Antiretroviral Switching in Colombia: A Retrospective Cohort Study.
  4. 692324
    “…In all four strains tested, 200 mg/kg EBO, which approximates the human oral equivalent dose of 500 mg, combined with SOC increased bacterial killing from 1.4 - 3.0 log(10) CFU compared to SOC alone resulting in total lung CFU reductions of 4.6 - 5.6 log(10). …”
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    1704. Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor, Demonstrates Potent Efficacy and Improves Efficacy of Standard of Care Regimen Against Mycobacterium avium complex in a Chronic Mouse Lung Infection Model
  5. 692325
    “…Hemoglobin (Hb), serum iron (Fe(2+)), serum ferritin (SF), soluble transferrin receptor (sTfR), hepcidin and the dosage of recombinant human erythropoietin (rhEPO) before and after intervention in patients were analyzed. …”
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    The prebiotic effects of soluble dietary fiber mixture on renal anemia and the gut microbiota in end-stage renal disease patients on maintenance hemodialysis: a prospective, randomized, placebo-controlled study
  6. 692326
    “…Angiogenic activities of GSLs in human umbilical vein endothelial cells (HUVECs) were evaluated. …”
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    Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis
  7. 692327
    “…We additionally estimated economic losses due to human immunodeficiency virus (HIV) attributable to herpes simplex virus type 2 (HSV-2) infections. …”
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    Estimated economic burden of genital herpes and HIV attributable to herpes simplex virus type 2 infections in 90 low- and middle-income countries: A modeling study
  8. 692328
    “…This study also suggests that dogs with subclinical MMVD, showed an increase in BNP along with a decrease in HDL-C and an increase in LDL-C, which are known to be risk factors for cardiovascular diseases in human. However, it seems that high LDL-C is more involved in the pathogenesis of MMVD than low HDL-C. …”
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    Diagnostic value of atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP) and their correlation with lipoproteins in dogs with myxomatous mitral valve disease
  9. 692329
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    Intracervical insemination versus intrauterine insemination with cryopreserved donor sperm in the natural cycle: a randomized controlled trial
  10. 692330
    “…The number of confirmed cases of COVID-19 is also rapidly increasing worldwide, posing a significant challenge to human safety. Asthma is a risk factor for COVID-19, but the underlying molecular mechanisms of the asthma–COVID-19 interaction remain unclear. …”
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    Bioinformatic analysis and preliminary validation of potential therapeutic targets for COVID-19 infection in asthma patients
  11. 692331
    “…Eventually, the expression level of FABP7, IGHD, SPIB, CTSW, IGKC, SEZ6, S100B, CXCL1, IGLV6-57 and CCL19 was identified as down-regulated in tumor cell line, while CPLX2 up-regulated, which was mostly similar with the results in TCGA and Human Protein Atlas (HPA) via RT-PCR. CONCLUSIONS: In summary, our study constructed a risk model composed of ARGs, which could be used as a solid model for predicting the survival and prognosis of BC patients. …”
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    Establishment and validation of an aging-related risk signature associated with prognosis and tumor immune microenvironment in breast cancer
  12. 692332
    “…CYTH4, DENND1C, AOAH, TBC1D10C, EPSTI1, GIMAP7, and FASL (FAS ligand) were novel predictors of ICB therapy and displayed high level of correlations with multiple immune checkpoints in melanoma and across 30 human cancers. We observed FAS ligand being among the most robust biomarkers of ICB treatment and constructed two novel and effective multigene panels predicting response to ICB therapy. …”
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    PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity
  13. 692333
    “…INTRODUCTION: Human Galectin-3 is a 32- to 35-kDa size lectin, mainly comprises a C-terminal carbohydrate recognition binding domain (CRD) and N-terminal domain. …”
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    Galectin-3 as a Potential Biomarker of Microvascular Complications in Patients with Type 2 Diabetes
  14. 692334
    “…The Clinical Proteomic Tumor Analysis Consortium and the Human Protein Atlas were used to assess the TBC1D10B protein expression. …”
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    Increased expression of TBC1D10B as a potential prognostic and immunotherapy relevant biomarker in liver hepatocellular carcinoma
  15. 692335
    “…Further, LINC00173 expression was significantly reduced in DDP-resistant LUAD cells and DDP-treated human LUAD tissues. Suppressed LINC00173 expression in LUAD cells enhanced DDP chemoresistance in vivo and in vitro, while restored LINC00173 expression in DDP-resistant LUAD cells markedly regained chemosensitivity to DDP. …”
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    Downregulation of Linc00173 increases BCL2 mRNA stability via the miR-1275/PROCA1/ZFP36L2 axis and induces acquired cisplatin resistance of lung adenocarcinoma
  16. 692336
    “…BACKGROUND: Due to the temporal and spatial heterogeneity of human epidermal growth factor receptor 2 (HER2) expression in breast tumors, immunohistochemistry (IHC) cannot accurately reflect the HER2 status in real time, which may cause misguided treatment decisions. …”
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    Molecular imaging of HER2 expression in breast cancer patients using a novel peptide-based tracer (99m)Tc-HP-Ark2: a pilot study
  17. 692337
    “…BACKGROUND: Studies in various countries including Uganda and Kenya have shown a much lower incidence of the human immunodeficiency virus (HIV) among men that underwent voluntary medical male circumcision (VMMC) compared to uncircumcised men. …”
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    Missed opportunity: low uptake of VMMC among men attending the OPD of a public health facility offering free VMMC services in Uganda
  18. 692338
    “…The aim of this study was to determine the involvement of human herpesvirus (HHV)-6A/B, HHV-7, and parvovirus B19 (B19V) in the etiopathogenesis of ME/CFS. …”
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    The persistent viral infections in the development and severity of myalgic encephalomyelitis/chronic fatigue syndrome
  19. 692339
    “…The University of San Francisco Quito, Research Ethics Committee in Human Beings approved the study, #2017- 127 M. The University of Kentucky Office of Research Integrity also approved the study, IRB # 42965). …”
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    The provision of the baby box was associated with safe sleep practices in a low-resource community: a randomized control trial in Ecuador
  20. 692340
    “…Analyses were stratified by the overall BRCA+ cohort and 4 molecular phenotypes: HER2+/HR- (human epidermal growth factor 2/hormone receptor), HER2−/HR+, HER2+/HR+, and triple negative BC (TNBC; HER2−/HR-). …”
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    Risk of seizures in a population of women with BRCA-positive metastatic breast cancer from an electronic health record database in the United States
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