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692401por Qin, Kai, Honjo, Kazuhito, Sherrill-Mix, Scott, Liu, Weimin, Stoltz, Regina M., Oman, Allisa K., Hall, Lucinda A., Li, Ran, Sterrett, Sarah, Frederick, Ellen R., Lancaster, Jeffrey R., Narkhede, Mayur, Mehta, Amitkumar, Ogunsile, Foluso J., Patel, Rima B., Ketas, Thomas J., Cruz Portillo, Victor M., Cupo, Albert, Larimer, Benjamin M., Bansal, Anju, Goepfert, Paul A., Hahn, Beatrice H., Davis, Randall S.“…Since these patients were also seropositive for endemic human coronaviruses (HCoVs), these responses likely reflect cross-reactive HCoV Abs rather than vaccine-induced de novo responses. …”
Publicado 2023
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692404“…Many residents voiced that they were uncomfortable performing a pericardiocentesis because they only had a few opportunities to do so on human cadavers, and they appreciated the opportunity to review this. …”
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692405“…DISCUSSION: As with any simulation model, this model does not perfectly recreate human anatomy. For example, in our model there were no simulated secretions or blood. …”
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692406“…SIMPLE SUMMARY: Recently updated results of clinical studies have confirmed that cyclin-dependent kinase 4/6 (CDK4/6) inhibitors such as palbociclib (Palbo), ribociclib (Ribo), and abemaciclib (Abem) plus letrozole/anastrozole (NSAI) significantly prolong survival compared to placebo plus NSAI in the first-line treatment of postmenopausal women with hormone receptor-positive (HR+) and human epidermal growth factor receptor-2 negative (HER2−) advanced or metastatic breast cancer (ABC). …”
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692407“…In contrast, innate effector cells such as NK cells and macrophages are naturally existing in human body as front line to defeat general pathogens and cancers,which will have a better safety profile. …”
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692408por Zaha, Cristian, Schuszler, Larisa, Dascalu, Roxana, Nistor, Paula, Florea, Tiana, Rujescu, Ciprian, Sicoe, Bogdan, Igna, Cornel“…ABSTRACT: Background: The field of veterinary medicine lacks information on equine thermal hoof printing, and few data on the same subject are available in dogs. In human medicine, thermography is used to detect heat emitted by the foot when it comes in contact with a flat surface to detect the abnormalities of the foot balance. …”
Publicado 2023
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692409por Lovric, Vedran, Crowley, James, Verma, Nikhil, Patt, Bradley, Walsh, William, Carter, Andrew“…This study evaluated the in vivo response of human DBF Patches (hDBF-P) as an onlay over the infraspinatus tendon (IST) and at the tendon-bone interface in an ovine model. …”
Publicado 2023
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692410“…METHODS: Eighteen fresh-frozen human cadaveric specimens (6 shoulder, 6 wrist, and 6 tibia) were utilized for this study. …”
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692411por Credille, Kevin, Wang, Zachary, Elias, Tristan, Inoue, Nozomu, Espinoza, Alejandro, Hevesi, Mario, Haneberg, Erik, Cole, Brian, Yanke, Adam“…The purpose of this study is to evaluate a novel topography matching technique for distal femoral condyle OCA transplantation using three-dimensional (3D) laser scanning to create 3D printed patient-specific instrumentation in a human cadaveric model. METHODS: Twelve cadaveric knees were dissected to isolate the distal femoral condyles (DFC) with cartilage intact and then 3D laser scanned. …”
Publicado 2023
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692412“…Although PIKFYVE phosphoinositide kinase inhibitors can selectively eliminate PIKFYVE-dependent human cancer cells in vitro and in vivo, the basis for this selectivity has remained elusive. …”
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692413por Mugabi, Benedicto, Nanyingi, Miisa, Kabanda, Richard, Ndibazza, Juliet, Elyanu, Peter, Asiimwe, John Baptist, Nazziwa, Gorret, Habaasa, Gilbert, Kekitiinwa, Adeodata“…Little is known about youth aged 15-24 years living with human immunodeficiency virus (YLHIV). There is a possible lack of SRHL in this population, considering the high rate of teenage pregnancies and unprotected sex reported by YLHIV. …”
Publicado 2023
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692414“…CONCLUSIONS: BA antagonizes Dex-induced apoptosis of human BMSCs by activating the HH signaling pathway. …”
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692415por Collins, Lauren F., Palella, Frank J., Mehta, C. Christina, Holloway, JaNae, Stosor, Valentina, Lake, Jordan E., Brown, Todd T., Topper, Elizabeth F., Naggie, Susanna, Anastos, Kathryn, Taylor, Tonya N., Kassaye, Seble, French, Audrey L., Adimora, Adaora A., Fischl, Margaret A., Kempf, Mirjam-Colette, Koletar, Susan L., Tien, Phyllis C., Ofotokun, Ighovwerha, Sheth, Anandi N.“…OBJECTIVE: To assess the association of human immunodeficiency virus on the burden of aging-related comorbidities among US adults in the modern treatment era. …”
Publicado 2023
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692416por Zhao, Yuanyuan, Chen, Gang, Chen, Jianhua, Zhuang, Li, Du, Yingying, Yu, Qitao, Zhuang, Wu, Zhao, Yanqiu, Zhou, Ming, Zhang, Weidong, Zhang, Yu, Wan, Yixin, Li, Wenting, Song, Weifeng, Wang, Zhongmin Maxwell, Li, Baiyong, Xia, Michelle, Yang, Yunpeng, Fang, Wenfeng, Huang, Yan, Zhang, Li“…AK112 is the first-in-class humanized IgG1 bispecific antibody targeting programmed death-1 (PD-1) and VEGF. …”
Publicado 2023
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692417por Jurja, Sanda, Negreanu-Pirjol, Ticuta, Vasile, Monica, Hincu, Mihaela Mehedinti, Coviltir, Valeria, Negreanu-Pirjol, Bogdan-Stefan“…INTRODUCTION: Medicine faces nowadays the trend of increasing life expectancy of human population, with the resulting increase of degenerative age related diseases prevalence, combined with the risks of less tempered sun radiations environment exposure. …”
Publicado 2023
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692418por Ramadanov, Nikolai, Jóźwiak, Katarzyna, Hauptmann, Michael, Lazaru, Philip, Marinova-Kichikova, Polina, Dimitrov, Dobromir, Becker, Roland“…BACKGROUND: Our aim was to determine the best operative procedure in human participants with a displaced or non-displaced femoral neck fracture comparing cannulated screw (CS) fixation, dynamic hip screw (DHS) fixation, hemiarthroplasty (HA), and total hip arthroplasty (THA) in terms of surgical and functional outcomes, reoperation and postoperative complications. …”
Publicado 2023
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692419por Li, Qing, Zhao, Yujing, Guo, Hongyan, Li, Qiao, Yan, Chaoying, Li, Yansong, He, Shuxuan, Wang, Nan, Wang, Qiang“…Here, starting with characterization of microglial accumulation of LDs in leptin receptor-deficient (db/db) mice and in high-fat diet and STZ (HFD/STZ) induced T2DM mice, as well as in high-glucose (HG)-treated mice BV2, human HMC3 and primary mice microglia, we revealed that HG-dampened lipophagy was responsible for LDs accumulation in microglia. …”
Publicado 2023
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692420“…In addition, CD147 immunohistochemistry in HCC was obtained from the Human Protein Atlas. CD147 expression patterns and clinical characteristics in the prognosis of HCC were analyzed by accessing the UALCAN web resource. …”
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