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692601por Beulens, Alexander J.W., Brinkman, Willem M., Koldewijn, Evert L., Hendrikx, Ad J.M., van Basten, Jean Paul A., van Merriënboer, Jeroen J.G., Van der Poel, Henk G., Bangma, Chris H., Wagner, Cordula“…MEASUREMENTS: Nontechnical skills will be observed using five different methods: (1) NOTSS: Nontechnical Skills for Surgeons; (2) Oxford NOTECHS II: a modified theatre team nontechnical skills scoring system; (3) OTAS: Observational Teamwork Assessment for Surgery; (4) Interpersonal and Cognitive Assessment for Robotic Surgery (ICARS): evaluation of nontechnical skills in robotic surgery; and (5) analysis of human factors. Technical skills in robot-assisted radical cystectomy will be analysed using two different methods: (1) GEARS: Global Evaluative Assessment of Robotic Skill and (2) GERT: Generic Error Rating Tool. …”
Publicado 2020
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692602“…TGFβ signaling plays crucial role during development and cancer, however the role for TGFβ signaling in regulating the noncoding part of the human genome in triple negative breast cancer (TNBC) is still being unraveled. …”
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692603por Ku, Anthony, Kondo, Misaki, Cai, Zhongli, Meens, Jalna, Li, Min Rong, Ailles, Laurie, Reilly, Raymond M.“…Region-of-interest (ROI) analysis of microPET/CT images provided dose estimates for the tumour and liver that were not significantly different for the two radioimmunoconjugates. Human doses from administration of [(177)Lu]Lu-DOTA-panitumumab F(ab')(2) predicted that a 2 cm diameter HNSCC tumour in a patient would receive 1.1–1.5 mSv/MBq and the whole body dose would be 0.15–0.22 mSv/MBq. …”
Publicado 2021
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692604“…BACKGROUND: Fremanezumab is a fully humanized monoclonal antibody (IgGΔa) that selectively targets calcitonin gene‐related peptide and is efficacious in reducing migraine frequency. …”
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692605por Suri, Arpita, Perumal, Vanamail, Ammalli, Prajwal, Suryan, Varsha, Bansal, Sanjiv Kumar“…Our study elucidates the diagnostic performance of Risk of Ovarian Malignancy Algorithm (ROMA), Human epididymis secretory protein 4 (HE4) and cancer antigen (CA125). …”
Publicado 2021
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692606por Thomas, Levin, Birangal, Sumit Raosaheb, Ray, Rajdeep, Sekhar Miraj, Sonal, Munisamy, Murali, Varma, Muralidhar, S.V., Chidananda Sanju, Banerjee, Mithu, Shenoy, Gautham G., Rao, Mahadev“…CONCLUSION: Predicting these potential drug–drug interactions, particularly related to CYP3A4, P-gp and the human Ether-à-go-go-Related Gene proteins, could be used in clinical settings for screening and management of drug–drug interactions for delivering safer chemotherapeutic tuberculosis and COVID-19 care. …”
Publicado 2021
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692609por Geskin, Larisa J, Garcia-Saleem, Tiffany, Akilov, Oleg E, Enz, Paula, Guenova, Emmanuella, Ortiz-Romero, Pablo L, Papadavid, Evangelia, Quaglino, Pietro, Rozati, Sima, Stonesifer, Connor, Burns, Austin, Khaleel, Alexandra, Scarisbrick, Julia J“…Actively managed patients with an established diagnosis of CL from March to October 2020 were included according to the Institutional Protection of Human Subjects guidelines at the respective centers. …”
Publicado 2021
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692610por Zaat, T R, de Bruin, J P, Goddijn, M, van Baal, M, Benneheij, E B, Brandes, E M, Broekmans, F, Cantineau, A E P, Cohlen, B, van Disseldorp, J, Gielen, S C J P, Groenewoud, E R, van Heusden, A, Kaaijk, E M, Koks, C, de Koning, C H, Klijn, N F, Lambalk, C B, van der Linden, P J Q, Manger, P, van Oppenraaij, R H F, Pieterse, Q, Smeenk, J, Visser, J, van Wely, M, Mol, FEnlace del recurso
Publicado 2021
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692611por Hernáez, Álvaro, Rogne, Tormod, Skåra, Karoline H, Håberg, Siri E, Page, Christian M, Fraser, Abigail, Burgess, Stephen, Lawlor, Deborah A, Magnus, Maria ChristineEnlace del recurso
Publicado 2021
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692612por Greilberger, Joachim, Herwig, Ralf, Greilberger, Michaela, Stiegler, Philipp, Wintersteiger, Reinhold“…A Jurkat cell line and human fibroblasts (HF-SAR) were cultivated in the absence or presence of combined AKG + 5-HMF solutions between 0 µg/mL aKG + 0 µg/mL 5-HMF and different concentrations of 500 µg/mL aKG + 166.7 µg/mL 5-HMF. …”
Publicado 2021
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692613por Sciacchitano, Salvatore, Capalbo, Carlo, Napoli, Christian, Negro, Andrea, De Biase, Luciano, Marcolongo, Adriano, Anibaldi, Paolo, Salvati, Valentina, Petrella, Lea, Merlo, Luca, Alampi, Daniela, Alessandri, Elisa, Loffredo, Chiara, Ulivieri, Alessandra, Lavra, Luca, Magi, Fiorenza, Morgante, Alessandra, Salehi, Leila B., De Vitis, Claudia, Mancini, Rita, Coluzzi, Flaminia, Rocco, Monica“…In addition, we retrieved data from transcriptome analysis, performed on human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM)s treated with T3 and we demonstrated that in these cells T3 is able to stimulate the expression of these two genes in a dose-dependent manner. …”
Publicado 2021
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692614por Karsten, M D A, Wekker, V, Groen, H, Painter, R C, Mol, B W J, Laan, E T M, Roseboom, T J, Hoek, AEnlace del recurso
Publicado 2021
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692615por Tarbell, Evan D, Van Wart, Scott A, Shah, Dhaval K, Walker, Laura M, Santulli, Andrew, Connolly, Lynn E, Mager, Donald E, Brown, Ashley N, Ambrose, Paul G“…BACKGROUND: ADG20 is a fully human IgG1 monoclonal antibody engineered to have potent and broad neutralization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other SARS-like CoVs with pandemic potential and an extended half-life. …”
Publicado 2021
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692616por Sader, Helio S, Paukner, Susanne, Gelone, Steven P, Arends, S J Ryan, Mendes, Rodrigo E“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support, Contract no. …”
Publicado 2021
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692617por Wierenga, Lara M, Doucet, Gaelle E, Dima, Danai, Agartz, Ingrid, Aghajani, Moji, Akudjedu, Theophilus N, Albajes‐Eizagirre, Anton, Alnæs, Dag, Alpert, Kathryn I, Andreassen, Ole A, Anticevic, Alan, Asherson, Philip, Banaschewski, Tobias, Bargallo, Nuria, Baumeister, Sarah, Baur‐Streubel, Ramona, Bertolino, Alessandro, Bonvino, Aurora, Boomsma, Dorret I, Borgwardt, Stefan, Bourque, Josiane, den Braber, Anouk, Brandeis, Daniel, Breier, Alan, Brodaty, Henry, Brouwer, Rachel M, Buitelaar, Jan K, Busatto, Geraldo F, Calhoun, Vince D, Canales‐Rodríguez, Erick J, Cannon, Dara M, Caseras, Xavier, Castellanos, Francisco X, Chaim‐Avancini, Tiffany M, Ching, Christopher RK, Clark, Vincent P, Conrod, Patricia J, Conzelmann, Annette, Crivello, Fabrice, Davey, Christopher G, Dickie, Erin W, Ehrlich, Stefan, van't Ent, Dennis, Fisher, Simon E, Fouche, Jean‐Paul, Franke, Barbara, Fuentes‐Claramonte, Paola, de Geus, Eco JC, Di Giorgio, Annabella, Glahn, David C, Gotlib, Ian H, Grabe, Hans J, Gruber, Oliver, Gruner, Patricia, Gur, Raquel E, Gur, Ruben C, Gurholt, Tiril P, de Haan, Lieuwe, Haatveit, Beathe, Harrison, Ben J, Hartman, Catharina A, Hatton, Sean N, Heslenfeld, Dirk J, van den Heuvel, Odile A, Hickie, Ian B, Hoekstra, Pieter J, Hohmann, Sarah, Holmes, Avram J, Hoogman, Martine, Hosten, Norbert, Howells, Fleur M, Hulshoff Pol, Hilleke E, Huyser, Chaim, Jahanshad, Neda, James, Anthony C, Jiang, Jiyang, Jönsson, Erik G, Joska, John A, Kalnin, Andrew J, Klein, Marieke, Koenders, Laura, Kolskår, Knut K, Krämer, Bernd, Kuntsi, Jonna, Lagopoulos, Jim, Lazaro, Luisa, Lebedeva, Irina S, Lee, Phil H, Lochner, Christine, Machielsen, Marise WJ, Maingault, Sophie, Martin, Nicholas G, Martínez‐Zalacaín, Ignacio, Mataix‐Cols, David, Mazoyer, Bernard, McDonald, Brenna C, McDonald, Colm, McIntosh, Andrew M, McMahon, Katie L, McPhilemy, Genevieve, van der Meer, Dennis, Menchón, José M, Naaijen, Jilly, Nyberg, Lars, Oosterlaan, Jaap, Paloyelis, Yannis, Pauli, Paul, Pergola, Giulio, Pomarol‐Clotet, Edith, Portella, Maria J, Radua, Joaquim, Reif, Andreas, Richard, Geneviève, Roffman, Joshua L, Rosa, Pedro GP, Sacchet, Matthew D, Sachdev, Perminder S, Salvador, Raymond, Sarró, Salvador, Satterthwaite, Theodore D, Saykin, Andrew J, Serpa, Mauricio H, Sim, Kang, Simmons, Andrew, Smoller, Jordan W, Sommer, Iris E, Soriano‐Mas, Carles, Stein, Dan J, Strike, Lachlan T, Szeszko, Philip R, Temmingh, Henk S, Thomopoulos, Sophia I, Tomyshev, Alexander S, Trollor, Julian N, Uhlmann, Anne, Veer, Ilya M, Veltman, Dick J, Voineskos, Aristotle, Völzke, Henry, Walter, Henrik, Wang, Lei, Wang, Yang, Weber, Bernd, Wen, Wei, West, John D, Westlye, Lars T, Whalley, Heather C, Williams, Steven CR, Wittfeld, Katharina, Wolf, Daniel H, Wright, Margaret J, Yoncheva, Yuliya N, Zanetti, Marcus V, Ziegler, Georg C, de Zubicaray, Greig I, Thompson, Paul M, Crone, Eveline A, Frangou, Sophia, Tamnes, Christian KEnlace del recurso
Publicado 2020
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692618por Ouergui, Ibrahim, Delleli, Slaheddine, Bouassida, Anissa, Bouhlel, Ezdine, Chaabene, Helmi, Ardigò, Luca Paolo, Franchini, Emerson“…TRIAL REGISTRATION: This study does not report results related to health care interventions using human participants and therefore it was not prospectively registered.…”
Publicado 2021
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692619por Singh, Aditi, Salaytah, Natali, Lebovic, Daniel, Sako, Zeyad, Pounders, Zachary, Kohler, Laura, Kafri, Zyad, Saravolatz, Louis, Coyle, Meredith, Patel, Hemang“…Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced coronavirus disease-2019 (COVID-19) has presented humanity with unprecedented challenges. Severe disease is associated with acute respiratory distress syndrome (ARDS), use of mechanical ventilation, ICU stay and prolonged hospitalization, The role of the immune system in the pathogenesis of COVID-19 disease is still unclear, which imposes limitations on identifying potential immunotherapy that can improve care for acute and chronic phases of COVID-19 in conjunction with current therapies. …”
Publicado 2021
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692620por Zhang, Zhe-Ao, Xin, Xin, Liu, Chao, Liu, Yan-hong, Duan, Hong-Xia, Qi, Ling-ling, Zhang, Ying-Ying, Zhao, He-ming, Chen, Li-Qing, Jin, Ming-Ji, Gao, Zhong-Gao, Huang, Wei“…The formation of the ApoE-enriched protein corona significantly improved the cellular uptake of Aβ-CN-PMs on C6 cells and human umbilical vein endothelial cells (HUVECs) and enhanced permeability to the blood–brain tumor barrier in vitro. …”
Publicado 2021
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