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692781por Danhof, N A, van Eekelen, R, Repping, S, Mol, B W J, van der Veen, F, van Wely, M, Mochtar, M HEnlace del recurso
Publicado 2020
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692782por Xie, Guoqiang, Zhang, Fan, Leung, Laura, Mooney, Michael A., Epprecht, Lorenz, Norton, Isaiah, Rathi, Yogesh, Kikinis, Ron, Al-Mefty, Ossama, Makris, Nikos, Golby, Alexandra J., O'Donnell, Lauren J“…We tracked the TGN using high-quality dMRI data from 100 healthy adult subjects from the Human Connectome Project (HCP). TGN tracking performance was compared across dMRI acquisitions with b = 1000 s/mm(2), b = 2000 s/mm(2) and b = 3000 s/mm(2), using single-tensor (1T) and two-tensor (2T) unscented Kalman filter (UKF) tractography. …”
Publicado 2020
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692783“…Studies using in vitro and in vivo models, in addition to human clinical studies have revealed that autophagy is pivotal for intestinal homeostasis maintenance, gut ecology regulation, appropriate intestinal immune responses and anti-microbial protection. …”
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692784por Gunning, Marlise N, Sir Petermann, Teresa, Crisosto, Nicolas, van Rijn, Bas B, de Wilde, Marlieke A, Christ, Jacob P, Uiterwaal, C S P M, de Jager, Wilco, Eijkemans, Marinus J C, Kunselman, Allen R, Legro, Richard S, Fauser, Bart C J MEnlace del recurso
Publicado 2020
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692785por Wang, Yujun, Lu, Rongrong, Wu, Guohui, Lan, Rong, Ou, Rong, Zhang, Yangchang, Ye, Mengliang“…Background: Male migrant workers (MMWs) have been reported to be vulnerable to human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). …”
Publicado 2020
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692786por Kim, Yong Dae, Noh, Kyoung Jin, Byun, Seong Jun, Lee, Soochahn, Kim, Tackeun, Sunwoo, Leonard, Lee, Kyong Joon, Kang, Si-Hyuck, Park, Kyu Hyung, Park, Sang Jun“…Evidence before this study. The human retina and optic disc continuously change with ageing, and they share physiologic or pathologic characteristics with brain and systemic vascular status. …”
Publicado 2020
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692787“…The presumed modes of transmission of LDV in nature and the events associated with its infection of mice are strikingly similar to those observed during the acute and asymptomatic phases of infection with human immunodeficiency virus (HIV) [24, 29, 74, 78]. …”
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692788por van Welie, N, Roest, I, Portela, M, van Rijswijk, J, Koks, C, Lambalk, C B, Dreyer, K, Mol, B W J, Finken, M J J, Mijatovic, VEnlace del recurso
Publicado 2020
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692789por Lainas, GT, Lainas, TG, Sfontouris, IA, Venetis, CA, Kyprianou, MA, Petsas, GK, Tarlatzis, BC, Kolibianakis, EMEnlace del recurso
Publicado 2020
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692790por Bordewijk, E M, Weiss, N S, Nahuis, M J, Kwee, J, Lambeek, A F, van Unnik, G A, Vrouenraets, F P J, Cohlen, B J, van de Laar-van Asseldonk, T A M, Lambalk, C B, Goddijn, M, Hompes, P G, van der Veen, F, Mol, B W J, van Wely, MEnlace del recurso
Publicado 2020
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692791por Osl, Theresa, Schmidt, Alexander, Schwaiger, Markus, Schottelius, Margret, Wester, Hans-Jürgen“…Comparative small animal PET imaging studies (1h p.i.) as well as in vivo biodistribution studies (1, 6 and 48h p.i.) were performed in Daudi (human B cell lymphoma) xenograft bearing CB17 SCID mice. …”
Publicado 2020
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692792por Guo, Wanjun, Tao, Yujie, Li, Xiaojing, Lin, Xia, Meng, Yajing, Yang, Xia, Wang, Huiyao, Zhang, Yamin, Tang, Wanjie, Wang, Qiang, Deng, Wei, Zhao, Liansheng, Ma, Xiaohong, Li, Mingli, Chen, Ting, Xu, Jiajun, Li, Jing, Hao, Wei, Lee, Sing, Coid, Jeremy W, Greenshaw, Andrew J, Li, Tao“…These results are important for informing health policymakers and service suppliers from the perspective of resolving the overall human health burden in the current era of “Internet Plus” and artificial intelligence.…”
Publicado 2020
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692793por Catford, S R, Lewis, S, Halliday, J, Kennedy, J, O’Bryan, M K, McBain, J, Amor, D J, Rombauts, L, Saffery, R, Hart, R J, McLachlan, R IEnlace del recurso
Publicado 2020
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692794por Hässler, Signe, Bachelet, Delphine, Duhaze, Julianne, Szely, Natacha, Gleizes, Aude, Hacein-Bey Abina, Salima, Aktas, Orhan, Auer, Michael, Avouac, Jerôme, Birchler, Mary, Bouhnik, Yoram, Brocq, Olivier, Buck-Martin, Dorothea, Cadiot, Guillaume, Carbonnel, Franck, Chowers, Yehuda, Comabella, Manuel, Derfuss, Tobias, De Vries, Niek, Donnellan, Naoimh, Doukani, Abiba, Guger, Michael, Hartung, Hans-Peter, Kubala Havrdova, Eva, Hemmer, Bernhard, Huizinga, Tom, Ingenhoven, Kathleen, Hyldgaard-Jensen, Poul Erik, Jury, Elizabeth C., Khalil, Michael, Kieseier, Bernd, Laurén, Anna, Lindberg, Raija, Loercher, Amy, Maggi, Enrico, Manson, Jessica, Mauri, Claudia, Mohand Oumoussa, Badreddine, Montalban, Xavier, Nachury, Maria, Nytrova, Petra, Richez, Christophe, Ryner, Malin, Sellebjerg, Finn, Sievers, Claudia, Sikkema, Dan, Soubrier, Martin, Tourdot, Sophie, Trang, Caroline, Vultaggio, Alessandra, Warnke, Clemens, Spindeldreher, Sebastian, Dönnes, Pierre, Hickling, Timothy P., Hincelin Mery, Agnès, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe“…In a multivariate Cox regression model including each of the clinical and genetic factors mentioned hereafter, among the clinical factors, immunosuppressants (adjusted hazard ratio [aHR] = 0.408 [95% confidence interval (CI) 0.253–0.657], p < 0.001) and antibiotics (aHR = 0.121 [0.0437–0.333], p < 0.0001) were independently negatively associated with time to ADA development, whereas infections during the study (aHR = 2.757 [1.616–4.704], p < 0.001) and tobacco smoking (aHR = 2.150 [1.319–3.503], p < 0.01) were positively associated. 351,824 Single-Nucleotide Polymorphisms (SNPs) and 38 imputed Human Leukocyte Antigen (HLA) alleles were analyzed through a genome-wide association study. …”
Publicado 2020
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692795por Raschi, Elena, Privitera, Daniela, Bodio, Caterina, Lonati, Paola Adele, Borghi, Maria Orietta, Ingegnoli, Francesca, Meroni, Pier Luigi, Chighizola, Cecilia Beatrice“…METHODS: ICs were purified from the sera of SSc patients bearing different autoantibody specificities (antibodies against DNA topoisomerase I, centromeric proteins, RNA polymerase, and Th/To), patients with systemic lupus erythematosus (SLE) and primary anti-phospholipid syndrome (PAPS), or healthy controls (NHS) using polyethylene glycol precipitation. Human umbilical vein endothelial cells (HUVECs) were incubated with ICs, positive and negative controls. mRNA levels of endothelin-1 (et-1), collagenIα1 (colIα1), interferon (IFN)-α, and IFN-β were investigated by real-time PCR; et-1 and il-6 mRNA levels were assessed after pre-treatment with bafilomycin. …”
Publicado 2020
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692796por Anderson, Richard A, Amant, Frédéric, Braat, Didi, D'Angelo, Arianna, Chuva de Sousa Lopes, Susana M, Demeestere, Isabelle, Dwek, Sandra, Frith, Lucy, Lambertini, Matteo, Maslin, Caroline, Moura-Ramos, Mariana, Nogueira, Daniela, Rodriguez-Wallberg, Kenny, Vermeulen, NathalieEnlace del recurso
Publicado 2020
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692797por Liu, Panpan, Huang, Zhijun, Yin, Mingzhu, Liu, Chun, Chen, Xiang, Pan, Pinhua, Kuang, Yehong“…We aim to explore the safety and efficacy of ixekizumab (an injectable drug for the treatment of autoimmune diseases) to prevent organ injury caused by the immune response to COVID-19. Ixekizumab is a human monoclonal antibody that binds to interleukin-17A and inhibits the release of pro-inflammatory cytokines and chemokines. …”
Publicado 2020
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692798por Arends, S J Ryan, Butler, Deborah, Scangarella-Oman, Nicole, Castanheira, Mariana, Mendes, Rodrigo E“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support)GlaxoSmithKline (Research Grant or Support)Melinta Therapeutics, Inc. …”
Publicado 2020
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692799por Castanheira, Mariana, Doyle, Timothy B, Hubler, Cory, Mendes, Rodrigo E, Sader, Helio S“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support)GlaxoSmithKline (Research Grant or Support)Melinta Therapeutics, Inc. …”
Publicado 2020
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692800“…(Research Grant or Support)Department of Health and Human Services (Research Grant or Support)GlaxoSmithKline (Research Grant or Support)Melinta Therapeutics, Inc. …”
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