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693041por Raymer, Michael G“…Introduction: Physics and Its Relation to Computer and Internet Technologies Physics, Silicon, and the "Magic" behind the Internet Age A Zoomed-In Look inside a Computer Timeline of Great Discoveries and Inventions in Physics and Computer and Communication Technologies The Methods and Significance of Science The Relation of Science and Information Technology Social Impacts: Science and Technology Mathematics: The Language of Science and Technology The Utility of Mathematics in Science and Technology Graphs Precision and Significant Digits Large and Small Numbers and Scientific Notation Real-World Example 2.1: Precision of Display Pixels Units for Physical Quantities Proportionality Binary Numbers The Concept of Information Exponential Growth Social Impacts: The Exponential Change of Nearly EverythingMechanics: Energy Enables Information TechnologyFrom Looms to Computers Speed, Acceleration, and Force In-Depth Look 3.1: Distance Traveled under Constant Acceleration Real-World Example 3.1: Seek Time of a Hard-Drive Head In-Depth Look 3.2: Net Force Vectors Real-World Example 3.2: Acceleration in Cathode-Ray TubesPrinciples of Mechanics Real-World Example 3.3: Force on a Hard-Drive Head The Physics of Energy Friction and Thermal Energy The Constancy of Energy Units for Mechanics Power Real-World Example 3.4: Motion Sensors in LaptopsSocial Impacts: Scientific Thought and Methods Have Arguably Changed the Course of Human History More Than Anything ElseMatter and Heat: Cooling Computers is Required by the Physics of ComputationFrom Steam Engines to ComputersMatter and AtomsGases, Liquids, and SolidsIn-Depth Look 4.1: Size and Numbers of AtomsReal-World Example 4.1: Growing Silicon Crystals for Computer ChipsPressure in a GasPressure in a LiquidPumps, Current, and ResistanceReal-World Example 4.2: A Water-Pressure-Operated ComputerTemperature The Ideal GasHeat and Thermal Energy TransferReal-World Example 4.3: Cooling Computer Chips Principles of Thermodynamics: Extracting Work from Heat Cooling Computers is Required by the Physics of Computation Social Impacts: The Industrial Revolution and the Information Revolution Electricity and Magnetism: The Workhorses of Information TechnologyElectricity and Magnetism Are the Basis of Computers and the Internet Electric ChargeIn-Depth Look 5.1: The Concept of Plus and Minus Electric ChargeElectric Forces: Coulomb's LawIn-Depth Look 5.2: The Discovery of the ElectronElectric FieldsIn-Depth Look 5.3: Electric Field LinesElectric Current and ConductorsElectrical Energy and VoltageReal-World Example 5.1: Capacitor Computer MemoryResistors, Conductors, and Ohm's LawElectrical Power MagnetismElectromagnetism Real-World Example 5.2: The Telegraph, Precursor to the Internet In-Depth Look 5.4: Magnetic Materials and Data StorageSocial Impacts: Innovation and Public Support of ScienceDigital Electronics and Computer LogicThe "Reasoning" Abilities of ComputersConcepts of LogicElectronic Logic CircuitsLogic Operations and DiagramsUsing Logic to Perform ArithmeticImplementing Logic with Electromagnetic SwitchesSupplemental Section: Boolean Search of Databases Chapter 7 Waves: Sound, Radio, and LightCommunicating with Sound, Radio, and Light Simple Harmonic Motion Damped and Complex Harmonic Motion Driven Harmonic Motion and Resonance In-Depth Look 7.1: Resonance Frequencies Real-World Example 7.1: Crystal Oscillators and Microprocessor Clocks WavesSimple Harmonic WavesInterference of WavesIn-Depth Look 7.2: Standing WavesSound WavesIn-Depth Look 7.3: BeatsWireless Radio WavesReal-World Example 7.2: AM RadioLet There Be Light WavesIn-Depth Look 7.4: Light PolarizationReal-World Example 7.3: LCD ScreensInterference of Light Social Impacts: Music, Science and Technology Analog and Digital CommunicationCommunication Systems: Analog and DigitalBasics of Analog RadioBasics of Digital Radio The Maximum Rate of Transmitting DataMaximum Data RateFrequency Multiplexing and BandwidthIn-Depth Look 8.1: Signal ReconstructionQuantum Physics of Atoms and MaterialsAtoms, Crystals, and ComputersThe Quantum Nature of Electrons and AtomsThe Experiments behind Quantum TheoryIn-Depth Look 9.1: Spectrum of Hydrogen AtomsThe Spinning of ElectronsThe Principles of Quantum PhysicsBuilding Up the AtomsReal-World Example 9.1: Fluorescent LampsElectrical Properties of MaterialsIn-Depth Look 9.2: Origin of the Energy Gap in Silicon CrystalsIn-Depth Look 9.3: Atomic Nature of Magnetic DomainsSocial Impacts: Science, Mysticism, and Pseudo-Science Semiconductor Physics: Transistors and CircuitsSilicon, Transistors, and Computers Controlling the Conductivity of Silicon p-n Junctions and Diodes Real-World Example 10.1: A Simple Crystal AM Radio ReceiverTransistors CMOS Computer Logic In-Depth Look 10.1: Water-Effect Transistors Miniaturization, Integrated Circuits, and Photolithography In-Depth Look 10.2: Bipolar Transistors Social Impacts: Labeling Every Object in the World Digital Memory and ComputersPhysics, Memory, and Computers Sequential Logic for Computer Memory Feedback Example #1: NOT Loop Feedback Example #2: One-Time Latch Static Random-Access Memory In-Depth Look 11.1: SRAM with Six Transistors Dynamic Random-Access Memory Nonvolatile Memory In-Depth Look 11.2: Quantum Tunneling Magnetic Tape and Hard Disk Memory Optical Compact Disk Memory Error Immunity of Digital Data The Structure of a Computer Hierarchy of Computer Memory Heat-Imposed Limits of Computers Representing Information in Computers using Codes Coding Images Data Compression Photons: Light Detectors and Light Emitting DiodesLight, Physics, and TechnologyThe Quantum Nature of Light-PhotonsPower and Energy in LightAbsorption of Light by Atoms and Crystals (or "How Einstein Got His Nobel Prize")In-Depth Look 12.1: Inability of Constant Voltage to Accelerate Electrons in an Insulator Real-World Example 12.1: Semiconductor Light DetectorsEmission of Light by Atoms and CrystalsReal-World Example 12.2: Light-Emitting DiodesSocial Impacts: Lighting the Darkness (Efficiently)Light and Optical Fibers for the InternetLight as a Communication MediumPropagation, Reflection and Transmission of LightLight in Transparent MediaRefraction of Light at a BoundaryReflection of Light at a BoundaryTotal Internal ReflectionPrisms and Speeds of Different Colored LightLenses and Curved MirrorsOptical Loss in Materials-The Clarity of Optical FiberLight GuidingOptical FibersLight Pulses in Optical FibersSocial Impacts: Total Immersion in a Sea of InformationLight Amplification and LasersAtoms and LasersThe Uniqueness of Laser LightAbsorption and Emission of Light by AtomsLaser ResonatorsIn-Depth Look 14.1: Laser Resonator FrequenciesHow a Laser WorksThe Helium-Neon LaserIn-Depth Look 14.2: Extreme Laser FactsVariable-Color Semiconductor LasersOvercoming Losses in Fiber-Optic SystemsQuantum Physics Description of LasersThe Semiconductor Diode LaserFiber-Optics CommunicationBandwidth and the Physics of WavesOverview of Fiber-Optical Communication SystemsModulating a Laser Beam with DataWavelength Multiplexing in Optical CommunicationThe Virtues of Lasers for Optical CommunicationHardware for Wavelength MultiplexingLaser Beam RoutingCommunication Networks and the InternetThe Physics behind the InternetThe Goals of Computer Communication NetworksNoise in Analog and Digital SystemsChallenges in NetworkingBroadcasting Networks and Switching NetworksFailure-Resistant CommunicationsWireless Mobile Cell Phone NetworksPropagation of Wireless Waves in TerrainSummary of Scientific Notation and UnitsSources and Credits for Quotes Used with PermissionGlossary.…”
Publicado 2009
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693042“…Pathologically, impaired copper metabolism due to environmental or genetic causes is implicated in a variety of human diseases, such as rare Wilson disease and common cancers. …”
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693043por Haiman, Christopher A, Hankinson, Susan E, Spiegelman, Donna, Colditz, Graham A, Willett, Walter C, Speizer, Frank E, Brown, Myles, Hunter, David J“…The protocol was approved by the Committee on Human Subjects, Brigham and Womens' Hospital, Boston, Massachusetts USA. …”
Publicado 2000
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693044por Goldbach-Mansky, Raphaela, Lee, Jennifer, McCoy, Angela, Hoxworth, Joseph, Yarboro, Cheryl, Smolen, Josef S, Steiner, Günter, Rosen, Antony, Zhang, Cindy, Ménard, Henri A, Zhou, Zhi Jie, Palosuo, Timo, Van Venrooij, Walther J, Wilder, Ronald L, Klippel, John H, Schumacher, H Ralph, EI-Gabalawy, Hani S“…AKA were detected using immunoflurescence on human epidermal tissue. RF was tested by nephelometry. …”
Publicado 2000
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693045por Chen, Jacqueline, Park, Kaitlyn, Uhm, Sun Young, Spinrad, Amelia, Uniya, Apurva, Pire-Smerkanich, Nancy, Pacifici, Eunjoo“…CTs are also conducted to understand normal human physiology, pathophysiology, and factors associated with health outcomes. …”
Publicado 2019
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693046por McManus, I. C., Harborne, Andrew Christopher, Horsfall, Hugo Layard, Joseph, Tobin, Smith, Daniel T., Marshall-Andon, Tess, Samuels, Ryan, Kearsley, Joshua William, Abbas, Nadine, Baig, Hassan, Beecham, Joseph, Benons, Natasha, Caird, Charlie, Clark, Ryan, Cope, Thomas, Coultas, James, Debenham, Luke, Douglas, Sarah, Eldridge, Jack, Hughes-Gooding, Thomas, Jakubowska, Agnieszka, Jones, Oliver, Lancaster, Eve, MacMillan, Calum, McAllister, Ross, Merzougui, Wassim, Phillips, Ben, Phillips, Simon, Risk, Omar, Sage, Adam, Sooltangos, Aisha, Spencer, Robert, Tajbakhsh, Roxanne, Adesalu, Oluseyi, Aganin, Ivan, Ahmed, Ammar, Aiken, Katherine, Akeredolu, Alimatu-Sadia, Alam, Ibrahim, Ali, Aamna, Anderson, Richard, Ang, Jia Jun, Anis, Fady Sameh, Aojula, Sonam, Arthur, Catherine, Ashby, Alena, Ashraf, Ahmed, Aspinall, Emma, Awad, Mark, Yahaya, Abdul-Muiz Azri, Badhrinarayanan, Shreya, Bandyopadhyay, Soham, Barnes, Sam, Bassey-Duke, Daisy, Boreham, Charlotte, Braine, Rebecca, Brandreth, Joseph, Carrington, Zoe, Cashin, Zoe, Chatterjee, Shaunak, Chawla, Mehar, Chean, Chung Shen, Clements, Chris, Clough, Richard, Coulthurst, Jessica, Curry, Liam, Daniels, Vinnie Christine, Davies, Simon, Davis, Rebecca, De Waal, Hanelie, Desai, Nasreen, Douglas, Hannah, Druce, James, Ejamike, Lady-Namera, Esere, Meron, Eyre, Alex, Fazmin, Ibrahim Talal, Fitzgerald-Smith, Sophia, Ford, Verity, Freeston, Sarah, Garnett, Katherine, General, Whitney, Gilbert, Helen, Gowie, Zein, Grafton-Clarke, Ciaran, Gudka, Keshni, Gumber, Leher, Gupta, Rishi, Harlow, Chris, Harrington, Amy, Heaney, Adele, Ho, Wing Hang Serene, Holloway, Lucy, Hood, Christina, Houghton, Eleanor, Houshangi, Saba, Howard, Emma, Human, Benjamin, Hunter, Harriet, Hussain, Ifrah, Hussain, Sami, Jackson-Taylor, Richard Thomas, Jacob-Ramsdale, Bronwen, Janjuha, Ryan, Jawad, Saleh, Jelani, Muzzamil, Johnston, David, Jones, Mike, Kalidindi, Sadhana, Kalsi, Savraj, Kalyanasundaram, Asanish, Kane, Anna, Kaur, Sahaj, Al-Othman, Othman Khaled, Khan, Qaisar, Khullar, Sajan, Kirkland, Priscilla, Lawrence-Smith, Hannah, Leeson, Charlotte, Lenaerts, Julius Elisabeth Richard, Long, Kerry, Lubbock, Simon, Burrell, Jamie Mac Donald, Maguire, Rachel, Mahendran, Praveen, Majeed, Saad, Malhotra, Prabhjot Singh, Mandagere, Vinay, Mantelakis, Angelos, McGovern, Sophie, Mosuro, Anjola, Moxley, Adam, Mustoe, Sophie, Myers, Sam, Nadeem, Kiran, Nasseri, Reza, Newman, Tom, Nzewi, Richard, Ogborne, Rosalie, Omatseye, Joyce, Paddock, Sophie, Parkin, James, Patel, Mohit, Pawar, Sohini, Pearce, Stuart, Penrice, Samuel, Purdy, Julian, Ramjan, Raisa, Randhawa, Ratan, Rasul, Usman, Raymond-Taggert, Elliot, Razey, Rebecca, Razzaghi, Carmel, Reel, Eimear, Revell, Elliot John, Rigbye, Joanna, Rotimi, Oloruntobi, Said, Abdelrahman, Sanders, Emma, Sangal, Pranoy, Grandal, Nora Sangvik, Shah, Aadam, Shah, Rahul Atul, Shotton, Oliver, Sims, Daniel, Smart, Katie, Smith, Martha Amy, Smith, Nick, Sopian, Aninditya Salma, South, Matthew, Speller, Jessica, Syer, Tom J., Ta, Ngan Hong, Tadross, Daniel, Thompson, Benjamin, Trevett, Jess, Tyler, Matthew, Ullah, Roshan, Utukuri, Mrudula, Vadera, Shree, Van Den Tooren, Harriet, Venturini, Sara, Vijayakumar, Aradhya, Vine, Melanie, Wellbelove, Zoe, Wittner, Liora, Yong, Geoffrey Hong Kiat, Ziyada, Farris, Devine, Oliver PatrickEnlace del recurso
Publicado 2020
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693047por Gorman, Ellen, Shankar-Hari, Manu, Hopkins, Phil, Tunnicliffe, William S., Perkins, Gavin D., Silversides, Jonathan, McGuigan, Peter, Jackson, Colette, Boyle, Roisin, McFerran, Jamie, McDowell, Cliona, Campbell, Christina, McFarland, Margaret, Smythe, Jon, Thompson, Jacqui, Williams, Barry, Curley, Gerard, Laffey, John G., Clarke, Mike, O’Kane, Cecilia, McAuley, Daniel F.“…INTERVENTION AND COMPARATOR: Intervention: Allogeneic donor CD362 enriched human umbilical cord derived mesenchymal stromal cells (REALIST ORBCEL-C) supplied as sterile, single-use cryopreserved cell suspension of a fixed dose of 400 x10(6) cells in 40ml volume, to be diluted in Plasma-Lyte 148 to a total volume of 200mls for administration. …”
Publicado 2020
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693048por Li, Jian, Pega, Frank, Ujita, Yuka, Brisson, Chantal, Clays, Els, Descatha, Alexis, Ferrario, Marco M., Godderis, Lode, Iavicoli, Sergio, Landsbergis, Paul A., Metzendorf, Maria-Inti, Morgan, Rebecca L., Pachito, Daniela V., Pikhart, Hynek, Richter, Bernd, Roncaioli, Mattia, Rugulies, Reiner, Schnall, Peter L., Sembajwe, Grace, Trudel, Xavier, Tsutsumi, Akizumi, Woodruff, Tracey J., Siegrist, Johannes“…CONCLUSIONS: We judged the existing bodies of evidence for human evidence as “inadequate evidence for harmfulness” for the exposure categories 41–48 and 49–54 h/week for IHD prevalence, incidence and mortality, and for the exposure category ≥55 h/week for IHD prevalence. …”
Publicado 2020
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693049por Diorio, Caroline, McNerney, Kevin O, Lambert, Michele P., Paessler, Michele, Chase, Julie, Gollomp, Kandace, Laskin, Benjamin L, Vella, Laura A, Henrickson, Sarah E, Liebling, Emily, Burudpakdee, Chakkapong, Lee, Jessica, Balamuth, Fran, Blatz, Allison M, Chiotos, Kathleen, Fitzgerald, Julie C, Giglia, Therese, Odom John, Audrey R, Petrosa, Whitney, Sullivan, Kathleen, Witmer, Char M, Bassiri, Hamid, Behrens, Edward M, Teachey, David T.“…Proinflammatory cytokines were measured using V-Plex Pro-inflammatory Panel 1 Human Kits and analyzed on a QuickPlex SQ120. P-values were computed using Dunn's multiple comparisons test after Kruskal-Wallis testing. …”
Publicado 2020
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693050por Wang, Zheng, Groen, Henk, Van Zomeren, Koen C, Cantineau, Astrid E P, Van Oers, Anne, Van Montfoort, Aafke P A, Kuchenbecker, Walter K H, Pelinck, Marie J, Broekmans, Frank J M, Klijn, Nicole F, Kaaijk, Eugenie M, Mol, Ben W J, Hoek, Annemieke, Van Echten-Arends, JannieEnlace del recurso
Publicado 2021
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693051por Zeng, Gang, Wu, Qianhui, Pan, Hongxing, Li, Minjie, Yang, Juan, Wang, Lin, Wu, Zhiwei, Jiang, Deyu, Deng, Xiaowei, Chu, Kai, Zheng, Wen, Wang, Lei, Lu, Wanying, Han, Bihua, Zhao, Yuliang, Zhu, Fengcai, Yu, Hongjie, Yin, Weidong“…The main outcomes of the study were geometric mean titres (GMTs), geometric mean increases (GMIs), and seropositivity of neutralising antibody to SARS-CoV-2 (virus strain SARS-CoV-2/human/CHN/CN1/2020, GenBank accession number MT407649.1), as analysed in the per-protocol population (all participants who completed their assigned third dose). …”
Publicado 2022
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693052por Javed, Farhan, Fayyaz, Harris, Al-Abadi, Eslam, Pickering, Warren, Leandro, Maria, Jeffery, Rachel“…Allergy to rituximab (Mabthera) prevented its further use; given the severity of reaction concerns, other biosimilar humanized anti-CD20 antibodies were considered, but difficult to obtain; deteriorating renal function with predominantly damaged kidneys and class V nephritis on biopsy and aiming to control immunology along with other active symptoms (arthritis, serositis–pleurisy, systemic symptoms, anaemia) options were limited. …”
Publicado 2021
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693053por Becker, Christian M, Bokor, Attila, Heikinheimo, Oskari, Horne, Andrew, Jansen, Femke, Kiesel, Ludwig, King, Kathleen, Kvaskoff, Marina, Nap, Annemiek, Petersen, Katrine, Saridogan, Ertan, Tomassetti, Carla, van Hanegem, Nehalennia, Vulliemoz, Nicolas, Vermeulen, NathalieEnlace del recurso
Publicado 2022
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693054por Yang, Guang, Zhou, Siyuan, He, Haoqiang, Shen, Zinuo, Liu, Yongmei, Hu, Jun, Wang, Jie“…Like “disease” is used in western medicine, “syndrome” is used in TCM to comprehend anomalous human conditions on the basis of patients’ symptoms, tongue, and pulse (Li et al., 2012). …”
Publicado 2022
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693055“…The October 1923 award of the Nobel Prize in Physiology or Medicine to FG Banting and JJR Macleod ignored Paulescu's scientific achievements in the treatment of experimental diabetes and rewarded the extraordinary advance of insulin treatment in human diabetes. B-At the end of August 2003, a few days before the date of the celebration at the Hôtel Dieu in Paris of the scheduled program of tribute to the scientific merits of NC Paulescu and his important contribution to the discovery of the antidiabetic hormone, convened by the Romanian Academy and the International Diabetes Federation, the Wiesenthal Foundation publicly accused the Romanian scientist of being an antisemite, an act that determined the cancellation of the announced events. …”
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693056por Okoro, Catherine A., Zhao, Guixiang, Fox, Jared B., Eke, Paul I., Greenlund, Kurt J., Town, Machell“…Estimated prevalence of cancer screenings, influenza vaccination, and having ever been tested for human immunodeficiency virus also varied by state, state Medicaid expansion status, expanded geographic region, and FPL category. …”
Publicado 2017
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693057por Cuadrado-Lavín, Antonio, Olmos, José Manuel, Cifrian, José Manuel, Gimenez, Teresa, Gandarillas, Marco Antonio, García-Saiz, Mar, Rebollo, Maria Henar, Martínez-Taboada, Victor, López-Hoyos, Marcos, Fariñas, María Carmen, Crespo, Javier“…Exclusion criteria: 1) Previous infection with SARS CoV2 (positive coronavirus PCR or positive serology with SARS Cov2 negative PCR and absence of symptoms); 2) Current treatment with hydroxychloroquine or chloroquine; 3) Hypersensitivity, allergy or any contraindication for taking hydroxychloroquine, in the technical sheet; 4) Previous or current treatment with tamoxifen or raloxifene; 5) Previous eye disease, especially maculopathy; 6) Known heart failure (Grade III to IV of the New York Heart Association classification) or prolonged QTc; 7) Any type of cancer (except basal cell) in the last 5 years; 6) Refusal to give informed consent; 8) Evidence of any other unstable or clinically significant untreated immune, endocrine, hematological, gastrointestinal, neurological, neoplastic or psychiatric illness; 9) Antibodies positive for the human immunodeficiency virus; 10) Significant kidney or liver disease; 11) Pregnancy or lactation. …”
Publicado 2020
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693058por Lu, Peng-Jun, Hung, Mei-Chuan, Srivastav, Anup, Grohskopf, Lisa A., Kobayashi, Miwako, Harris, Aaron M., Dooling, Kathleen L., Markowitz, Lauri E., Rodriguez-Lainz, Alfonso, Williams, Walter W.“…REPORTING PERIOD: August 2017–June 2018 (for influenza vaccination) and January–December 2018 (for pneumococcal, herpes zoster, tetanus and diphtheria [Td]/tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis [Tdap], hepatitis A, hepatitis B, and human papillomavirus [HPV] vaccination). DESCRIPTION OF SYSTEM: The National Health Interview Survey (NHIS) is a continuous, cross-sectional national household survey of the noninstitutionalized U.S. civilian population. …”
Publicado 2021
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693059por Bergman, Hanna, Henschke, Nicholas, Hungerford, Daniel, Pitan, Femi, Ndwandwe, Duduzile, Cunliffe, Nigel, Soares-Weiser, Karla“…SEARCH METHODS: On 30 November 2020, we searched PubMed, the Cochrane Infectious Diseases Group Specialized Register, CENTRAL (published in the Cochrane Library), Embase, LILACS, Science Citation Index Expanded, Social Sciences Citation Index, Conference Proceedings Citation Index‐Science, Conference Proceedings Citation Index‐Social Science & Humanities. We also searched the WHO ICTRP, ClinicalTrials.gov, clinical trial reports from manufacturers' websites, and reference lists of included studies, and relevant systematic reviews. …”
Publicado 2021
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693060por Wang, X.W., Han, P.J., Bai, F.Y., Luo, A., Bensch, K., Meijer, M., B., Kraak, Han, D.Y., Sun, B.D., Crous, P.W., Houbraken, J.“…Chaetomiaceae comprises phenotypically diverse species, which impact biotechnology, the indoor environment and human health. Recent studies showed that most of the traditionally defined genera in Chaetomiaceae are highly polyphyletic. …”
Publicado 2022
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