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  1. 1
    por Srivastava, M.V. P.
    Publicado 2020
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    Perplexing Perspectives of ICAD
  2. 2
    “…ICAD/DFF has two alternative isoforms, long isoform (ICAD‐L/DFF45) and short isoform (ICAD‐S/DFF35). …”
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    Expression of ICAD‐L and ICAD‐S in Human Brain Tumor and Its Cleavage upon Activation of Apoptosis by Anti‐Fas Antibody
  3. 3
    “…The International Children's Accelerometry Database (ICAD) project pooled and reduced raw accelerometer data using standardized methods to create comparable outcome variables across studies. …”
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    International children's accelerometry database (ICAD): Design and methods
  4. 4
    “…Biochemical studies revealed that CAD forms an inactive heterodimer with the inhibitor of caspase-activated DNase (ICAD), or its alternatively spliced variant, ICAD-S, in the cytoplasm. …”
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    Determinants of the Nuclear Localization of the Heterodimeric DNA Fragmentation Factor (Icad/Cad)
  5. 5
    por Kwon, Soyang, Janz, Kathleen F
    Publicado 2012
    “…METHODS: Data from ALSPAC, CLAN, Iowa Bone Development Study, HEAPS, PEACH were extracted from the International Children’s Accelerometry Database (ICAD), resulting in 5,016 participants with age, gender, and accelerometry data at both baseline and follow-up (mean age: 10.3 years at baseline, 12.5 years at follow-up). …”
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    Tracking of accelerometry-measured physical activity during childhood: ICAD pooled analysis
  6. 6
    “…BACKGROUND AND OBJECTIVES: Although the main mechanisms of stroke in patients with intracranial atherosclerotic disease (ICAD)—perforating artery occlusion (PAO) and artery-to-artery embolism (AAE)—have been identified and described, relatively little is known about the morphology of the symptomatic plaques and how they differ between these 2 mechanisms. …”
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    Association of Plaque Morphology With Stroke Mechanism in Patients With Symptomatic Posterior Circulation ICAD
  7. 7
    “…METHODS: The International Children’s Accelerometry Database (ICAD) consists of ActiGraph accelerometer data from 20 studies in ten countries, processed using common data reduction procedures. …”
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    Objectively measured physical activity and sedentary time in youth: the International children’s accelerometry database (ICAD)
  8. 8
    “…We show that ICAD deficiency may be associated with colon malignancy in humans. …”
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    ICAD Deficiency in Human Colon Cancer and Predisposition to Colon Tumorigenesis: Linkage to Apoptosis Resistance and Genomic Instability
  9. 9
    “…METHODS: Accelerometer data from 24,316 children aged 5 to 18 years were extracted from the International Children’s Accelerometer Database (ICAD) 2.0. Correlation coefficients between wear time, sedentary behavior (SB), light-intensity PA (LPA), moderate-intensity PA (MPA), vigorous-intensity PA (VPA), moderate- and vigorous-intensity PA (MVPA), and total activity counts (TAC) were calculated. …”
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    A closer look at the relationship among accelerometer-based physical activity metrics: ICAD pooled data
  10. 10
    “…No significant association was found between ICAD intensity and grade of RCC. In summary, down-regulation of ICAD occurs in RCC. …”
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    Decreased Expression of Inhibitor of Caspase-Activated DNase (ICAD) in Renal Cell Carcinoma – Tissue Microarray of Human Samples
  11. 11
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    Correction to: A closer look at the relationship among accelerometer-based physical activity metrics: ICAD pooled data
  12. 12
    “…This was also suppressed by treatment with a Ca(2+)-specific chelator, which suggested that CAD endonuclease does not contribute. Moreover, no obvious ICAD reduction/degradation was detected. Conclusion: Daunorubicin effectively eliminated CSCs, which are dependent on the p53/caspase signaling cascade. …”
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    Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation
  13. 13
    “…There was a greater correlation between the presence of both icaA and icaD and the slime production than the single expression of icaA or icaD and the presence of slime in all groups. …”
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    Analysis of S. Epidermidis icaA and icaD genes by polymerase chain reaction and slime production: a case control study
  14. 14
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    Tracking of total sedentary time and sedentary patterns in youth: a pooled analysis using the International Children’s Accelerometry Database (ICAD)
  15. 15
    “…The isolates were S. epidermidis KA 15.8 (ICA+), a known biofilm producer isolate positive for icaA, icaD and bap genes, and S. epidermidis KA 14.5 (ICA-), known as a non-biofilm producer isolate negative for icaA, icaD and bap genes. …”
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    Comparison of Biofilm Formation Capacities of Two Clinical Isolates of Staphylococcus Epidermidis with and without icaA and icaD Genes on Intraocular Lenses
  16. 16
    “…METHODS: Cross-sectional data from 14 studies (7 countries) in the International Children’s Accelerometry Database (ICAD, 1998–2009) was included. Accelerometry in 19,502 participants aged 3–18 years, together with covariate and outcome data, was pooled and harmonized. …”
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    Substituting prolonged sedentary time and cardiovascular risk in children and youth: a meta-analysis within the International Children’s Accelerometry database (ICAD)
  17. 17
    “…Guidance documents and facilities to enable the creation of new harmonised variables were also devised and made available to ICAD users. An expanded ICAD database was made available in May 2017. …”
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    Harmonising data on the correlates of physical activity and sedentary behaviour in young people: Methods and lessons learnt from the international Children’s Accelerometry database (ICAD)
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    Biofilm forming capacity and antibiotic susceptibility of Staphylococcus spp. with the icaA/icaD/bap genotype isolated from ocular surface of patients with diabetes
  19. 19
    “…METHODS: We analysed pooled data from 13 studies comprising 18,200 children and adolescents aged 4–18 years from the International Children’s Accelerometry Database (ICAD). Waist-mounted accelerometers measured sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). …”
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    Cross-Sectional Associations of Reallocating Time Between Sedentary and Active Behaviours on Cardiometabolic Risk Factors in Young People: An International Children’s Accelerometry Database (ICAD) Analysis
  20. 20
    “…CAD is normally activated in apoptosis as a result of caspase cleavage of its inhibitory chaperone ICAD. Other aspects of CAD regulation are poorly understood. …”
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    Auxin-induced Rapid Degradation of Inhibitor of Caspase-activated DNase (ICAD) Induces Apoptotic DNA Fragmentation, Caspase Activation, and Cell Death: A CELL SUICIDE MODULE
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