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  1. 2101
    “…Eight pathogenic germline mutations were detected in 7 AML patients, in three genes: CEBPA, ETV6, and IDH2. One patient had two pathogenic germinal mutations, one in ETV6 and one in CEBPA gene. …”
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    Germline mutations among Polish patients with acute myeloid leukemia
  2. 2102
    “…Three independent radiomics models (PET-Rad Model, CT-Rad Model and PET/CT-Rad Model) predicting IDH mutation status were generated using the least absolute shrinkage and selection operator (LASSO) regression analysis based on machine learning algorithms. …”
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    Integrated CT Radiomics Features Could Enhance the Efficacy of (18)F-FET PET for Non-Invasive Isocitrate Dehydrogenase Genotype Prediction in Adult Untreated Gliomas: A Retrospective Cohort Study
  3. 2103
    “…Using an MRI with non-contrast and post-contrast T1-weighted sequences and FLAIR, our workflow automatically predicts the IDH1/2 mutation, the ATRX expression loss, the 1p19q co-deletion and the MGMT methylation status. …”
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    Fully Automated MR Based Virtual Biopsy of Cerebral Gliomas
  4. 2104
    “…T3 of leg/total% was associated with 49% lower, 41% lower, and unchanged relative odds of isolated diastolic hypertension (IDH), systolic-diastolic hypertension (SDH), and isolated systolic hypertension (ISH) compared to T1 (IDH: 0.51, 0.37–0.70; SDH: 0.59, 0.43–0.80; ISH: 1.06, 0.70–1.59). …”
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    Leg and arm adiposity is inversely associated with diastolic hypertension in young and middle-aged United States adults
  5. 2105
    “…There were16 cases of WHO III, 40 cases of WHO IV, 13 cases of IDH mutation (IDHmt), 30 cases of wildtype (wt) and 13 cases of NOS. …”
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    Patterns of local failure in patients with high-grade glioma after postoperative radiotherapy with or without chemotherapy
  6. 2106
    “…Analyses of 86 proteins associated with CNS cell-typing or known neurodegenerative changes in 168 ROIs from 14 individuals identified 11 proteins displaying differential expression in NFT-bearing neurons of the resilient when compared to the demented (including APP, IDH1, CD68, GFAP, SYP and Histone H3). In addition, IDH1, CD68, and SYP were differentially expressed in the environment of NFT-bearing neurons when comparing resilient to demented. …”
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    Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling
  7. 2107
    “…Eligible patients without somatic H3 K27M or BRAF mutations were enrolled on Stratum 1 (IDH wild-type) or Stratum 2 (IDH mutant). Protocol radiochemotherapy consisted of involved field radiotherapy with concurrent veliparib at 65 mg/m(2) twice daily. …”
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    HGG-06. Phase 2 Study of Veliparib and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients with Newly Diagnosed High-Grade Glioma without H3 K27M or BRAF Mutations: A Report from the Children's Oncology Group ACNS1721 Study
  8. 2108
    “…Ongoing analysis reveals genetic alterations in 95% of available tumours. IDH-mutant tumours account for only 53%, while paediatric-type mutations were found in 35% of AYA tumours with IDH-WT GBM accounting for the remaining 12%. …”
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    LGG-41. The clinical and molecular landscape of gliomas in adolescents and young adults
  9. 2109
    “…Moreover, the concentrations of Gln and NE in follicular fluid showed significantly positive correlation with IDH1 expression in GCs (R = 0.3822, R = 0.4009, P < 0.05). …”
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    Glutamine and norepinephrine in follicular fluid synergistically enhance the antioxidant capacity of human granulosa cells and the outcome of IVF-ET
  10. 2110
    Publicado 2019
    Tabla de Contenidos: “…/ Marina Montoto Ugarte -- La antropología forense ante la Corte IDH / Ana Buriano Castro.…”
    Libro
    Pasados recientes, violencias actuales : antropologia forense, cuerpos y memorias /
  11. 2111
    “…Here, we describe two cases of RIG diagnosed as glioblastoma (GB), IDH-wildtype, in adults who had previously received central nervous system radiation for childhood cancers. …”
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    Case report: Radiographic complete response of radiation-induced glioblastoma to front-line radiotherapy: A report and molecular characterization of two unique cases
  12. 2112
    “…However, advancements in medical research have introduced targeted therapies, initially employing monoclonal antibodies such as ant-CD52 and anti-CD123, and subsequently utilizing specific inhibitors that target molecular mutations like anti-IDH1, IDH2, or FLT3. The challenge lies in determining the role of these therapeutic options, considering the inherent tumor heterogeneity associated with leukemia diagnosis and the clonal drift that this type of tumor can undergo. …”
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    The Contribution of Multiplexing Single Cell RNA Sequencing in Acute Myeloid Leukemia
  13. 2113
    “…In particular, S100A6 upregulation in glioma tissues exhibited a significant and positive correlation with the World Health Organization (WHO) grade, histological type, age, sex, primary treatment outcomes, 1p/19q codeletion, isocitrate dehydrogenase (IDH) status, overall survival (OS), progression-free interval and disease-specific survival. …”
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    S100A6 is a potential diagnostic and prognostic biomarker for human glioma
  14. 2114
    “…CONCLUSION: PRAME expression statuses may dictate different biological and clinicopathological profiles in IDH-wildtype glioblastoma.…”
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    Molecular and clinicopathological implications of PRAME expression in adult glioma
  15. 2115
    “…BACKGROUND: Branched-chain aminotransferase 1 (BCAT1) has been proposed to drive proliferation and invasion of isocitrate dehydrogenase (IDH) wild-type glioblastoma cells. However, the Cancer Genome Atlas (TCGA) dataset shows considerable variation in the expression of this enzyme in glioblastoma. …”
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    The role of branched-chain aminotransferase 1 in driving glioblastoma cell proliferation and invasion varies with tumor subtype
  16. 2116
    “…The risk score was stratified by age, gender, WHO grade, IDH1 mutation, MGMT promoter methylation, and 1p/19q codeletion status, and a nomogram was constructed and validated. …”
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    Transcriptomic Characterization of Copper-Binding Proteins for Predicting Prognosis in Glioma
  17. 2117
    “…Furthermore, the interactions discovered herein are compared to IDH-mutant astrocytoma, allowing for focus on the cellular ecosystem unique to GBM. …”
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    Single-cell analysis reveals diversity of tumor-associated macrophages and their interactions with T lymphocytes in glioblastoma
  18. 2118
    “…Interestingly, these rare intravascular cells showing EGFR amplification by CISH or mutant IDH1 protein by immunohistochemistry were located in the middle or outer portions of vessel walls, but not amongst the morphologic boundaries of the endothelial lining. …”
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    Neoplastic cells are a rare component in human glioblastoma microvasculature
  19. 2119
    “…This was repeated for two other published signatures and the performance of LDA equations was evaluated on an independent test set, which contained status of IDH1 mutation, EGFR amplification, MGMT methylation and gene VEGF expression, among other clinical and molecular information. …”
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    Development of robust discriminant equations for assessing subtypes of glioblastoma biopsies
  20. 2120
    “…Applying this levels-of-evidence system to MGMT, IDH1, 1p19q, Ki67, MYCC, MYCN and β-catenin, only immunohistochemical IDH1 mutation testing in patients with diffuse gliomas is supported by sufficient evidence in order to be unequivocally qualified for clinical use. …”
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    Clinical Neuropathology Practice Guide 3-2013: levels of evidence and clinical utility of prognostic and predictive candidate brain tumor biomarkers
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