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2501
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2502por Brett, Judith, Bull, Ann, Burrell, Simon, Wang, Ling, Kalman, Tali, Veale, Hilary, Hennessy, Daneeta, Rowe, Stacey, Lim, Lyn-li, Worth, LeonEnlace del recurso
Publicado 2022
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2503
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2504
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2505por Dempster, Penelope, Hutchinson, Anastasia (Ana), Oldland, Elizabeth, Bouchoucha, StéphaneEnlace del recurso
Publicado 2022
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2506por Digby, Robin, Hopper, Ingrid, Hughes, Leanne, McCaskie, Doug, Tuck, Michelle, Fallon, Kethly, Hunter, Peter, Bucknall, TraceyEnlace del recurso
Publicado 2022
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2507por Teske, Nico, Teske, Nina C., Niyazi, Maximilian, Belka, Claus, Thon, Niklas, Tonn, Joerg-Christian, Forbrig, Robert, Karschnia, Philipp“…However, tumor regrowth including distant foci may occur in a subset of IDH-wildtype glioblastoma patients diagnosed per WHO 2021 classification. …”
Publicado 2023
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2508por Xu, Xiaoyan, Wang, Hong, Han, Haohao, Yao, Yifang, Li, Xueqian, Qi, Jiaqian, Cai, Chengsen, Zhou, Meng, Tang, Yaqiong, Pan, Tingting, Zhang, Ziyan, Yang, Jingyi, Wu, Depei, Han, Yue“…However, there are limited data on the comprehensive analysis of DNA methylation regulated gene mutations (DMRGM) in acute myeloid leukemia (AML) mainly referring to DNA methyltransferase 3α (DNMT3A), isocitrate dehydrogenase 1 (IDH1), isocitrate dehydrogenase 2 (IDH2), and Tet methylcytidine dioxygenase 2 (TET2). …”
Publicado 2023
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2509por Rosenbaum, Adam, Dahlin, Anna M., Andersson, Ulrika, Björkblom, Benny, Wu, Wendy Yi-Ying, Hedman, Håkan, Wibom, Carl, Melin, Beatrice“…Gene expression data of IDH1 mutated LGGs from the cancer genome atlas (TCGA) revealed a similar under expression of type I interferon genes associated with the risk allele. …”
Publicado 2023
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2510“…Kaplan–Meier analysis revealed that patients with IDH wide type or IL-13Rα2 had worst overall survival (OS) compared to other biomarkers. …”
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2511por Kim, Min-Sung, Go, Se-Il, Wee, Chan Woo, Lee, Min Ho, Kang, Seok-Gu, Go, Kyeong-O, Kwon, Sae Min, Kim, Woohyun, Dho, Yun-Sik, Park, Sung-Hye, Seo, Youngbeom, Song, Sang Woo, Ahn, Stephen, Oh, Hyuk-Jin, Yoon, Hong In, Lee, Sea-Won, Lee, Joo Ho, Cho, Kyung Rae, Choi, Jung Won, Hong, Je Beom, Hwang, Kihwan, Park, Chul-Kee, Lim, Do Hoon“…For patients with newly diagnosed astrocytoma with isocitrate dehydrogenase (IDH)-mutant and oligodendroglioma with IDH-mutant/1p19q codeleted, observation was preferred for patients with low-risk, World Health Organization (WHO) grade 2, and Karnofsky Performance Scale (KPS) ≥60, while adjuvant radiotherapy alone was preferred for patients with high-risk, WHO grade 2, and KPS ≥60. …”
Publicado 2023
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2512por Yuan, Yunbo, Zuo, Mingrong, Zhang, Shuxin, Chen, Siliang, Feng, Wentao, Wang, Zhihao, Chen, Mina, Liu, Yanhui“…RESULTS: Seventy-five ROGs were found and consensus clustering using the expression profile of ROGs divided the both IDH-mutant (IDHmut) and IDH-wildtype (IDHwt) HGGs into subclusters with different prognosis. …”
Publicado 2023
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2513por Aristizábal-Ocampo, Dagnovar, Álvarez-Montoya, Diego, Madrid-Muñoz, Camilo, Fallon-Giraldo, Simon, Gallo-Villegas, Jaime“…In isolated diastolic hypertension (IDH), the cardiac index (CI) was greater than that in normotensive (N) controls (CI: IDH vs. …”
Publicado 2023
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2514por Wang, Christina H., Negoianu, Dan, Zhang, Hanjie, Casper, Sabrina, Hsu, Jesse Y., Kotanko, Peter, Raimann, Jochen, Dember, Laura M.“…Low starting PRR has a higher hazard of IDH, whereas high starting PRR was protective (hazard ratio [HR], 1.26, 95% confidence interval [CI], 1.18 to 1.35 versus HR, 0.79, 95% CI, 0.73 to 0.85, respectively). …”
Publicado 2023
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2515por Zhong, Jingyu, Lu, Junjie, Zhang, Guangcheng, Mao, Shiqi, Chen, Haoda, Yin, Qian, Hu, Yangfan, Xing, Yue, Ding, Defang, Ge, Xiang, Zhang, Huan, Yao, Weiwu“…The convincing level of evidence was rated in (1) T2-FLAIR radiomics for IDH-mutant vs IDH-wide type differentiation in low-grade glioma, (2) CT radiomics for COVID-19 vs other viral pneumonia differentiation, and (3) MRI radiomics for high-grade glioma vs brain metastasis differentiation. …”
Publicado 2023
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2516“…A few studies mentioned IDH-mutant astrocytomas or oligodendrogliomas. The most common molecular targets in published clinical studies and clinical trials were protein kinase pathways, followed by microenvironmental targets, immunotherapy, and cell cycle/apoptosis pathways. …”
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2517por Tang, Xiaohu, Lin, Chao-Chieh, Spasojevic, Ivan, Iversen, Edwin S, Chi, Jen-Tsan, Marks, Jeffrey R“…However, high levels of 2-HG were not associated with somatic mutations or expression levels of IDH1 or IDH2. BRCA1 mRNA levels were positively associated with coenzyme A, acetyl coenzyme A, and GSH and negatively associated with multiple lipid species, supporting the regulation of ACC1 and NRF2 by BRCA1. …”
Publicado 2014
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2518por Yong, William H., Shabihkhani, Maryam, Telesca, Donatello, Yang, Shuai, Tso, Jonathan L., Menjivar, Jimmy C., Wei, Bowen, Lucey, Gregory M., Mareninov, Sergey, Chen, Zugen, Liau, Linda M., Lai, Albert, Nelson, Stanley F., Cloughesy, Timothy F., Tso, Cho-Lea“…Moreover, tumors that exhibited unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) or wild-type isocitrate dehydrogenase 1 (IDH1) were associated with higher RPS11 expression levels [corr (IDH1, RPS11) = 0.64, p = 0.03); [corr (MGMT, RPS11) = 0.52, p = 0.04]. …”
Publicado 2015
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2519por Wu, Yun, Liu, Fen, Adi, Dilare, Yang, Yi-Ning, Xie, Xiang, Li, Xiao-Mei, Ma, Xiang, Fu, Zhen-Yan, Huang, Ying, Chen, Bang-Dang, Shan, Chun-Fang, Ma, Yi-Tong“…Among the studied populations, Han participants with SDH, Uygur participants with SDH and ISH, and Kazakh with IDH were more likely to suffer carotid atherosclerosis than those with other subtypes of hypertension. …”
Publicado 2017
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2520por Xu, Liangjing, Xu, Jinge, Ma, Shoubao, Li, Xiaoli, Zhu, Mingqing, Chen, Suning, Han, Yue, Tang, Xiaowen, Fu, Zhengzheng, Qiu, Huiying, Yu, Jianhua, Wu, Depei, Wu, Xiaojin“…The mutations of the following six genes, i.e., FLT3-ITD, NPM1, C-KIT, IDH1/IDH2, DNMT3A, were independent of the Tim-3 expression. …”
Publicado 2017
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