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Mostrando 341 - 360 Resultados de 4,168 Para Buscar '"IDH"', tiempo de consulta: 0.17s Limitar resultados
  1. 341
    “…BACKGROUND: As molecular advances have deepened the knowledge on low-grade glioma (LGG), we investigated the effect of higher radiation dose on the survival of IDH-wildtype (IDHwt) LGG. METHODS: In the current study, 52 IDHwt LGG patients who received radiotherapy were enrolled from the Chinese Glioma Genome Atlas dataset. …”
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    High-dose radiation associated with improved survival in IDH-wildtype low-grade glioma
  2. 342
    “…These study results suggested that TEAD4 variations were independent predictive biomarkers for the prognosis in patients with LGG with IDH mutation.…”
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    TEAD4 is a novel independent predictor of prognosis in LGG patients with IDH mutation
  3. 343
    “…BACKGROUND: Recent studies have identified that glioblastoma IDH-wildtype (GBM IDH-WT) might be comprised of molecular subgroups with distinct prognoses. …”
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    The role of RB1 alteration and 4q12 amplification in IDH-WT glioblastoma
  4. 344
    “…Forty-three patients with primary, isocitrate dehydrogenase 1 (IDH1) wild type glioblastomas (GBMs) were included in this study. …”
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    Phosphorous Magnetic Resonance Spectroscopy and Molecular Markers in IDH1 Wild Type Glioblastoma
  5. 345
    “…Remarkably, the authors find that high‐ITH tumors highly overlap with the IDH (isocitrate dehydrogenase)‐mutant subgroup (IDH‐SG), comprising of IDH‐mutated tumors and IDH‐like tumors, that is, those IDH‐wildtype tumors that exhibit similar molecular profiles to the IDH‐mutated ones. …”
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    IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma
  6. 346
    “…Histology and genetic analysis of the pontine biopsy were consistent with grade 3 oligodendroglioma, and comparison of the two lesions demonstrated common 1p/19q co-deletions and TERT promoter mutations but distinct IDH1 mutations, with a non-canonical IDH1 R132G mutation identified in the infratentorial lesion and a R132H mutation identified in the cortical lesion. …”
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    Synchronous supratentorial and infratentorial oligodendrogliomas with incongruous IDH1 mutations, a case report
  7. 347
    “…Interestingly, IDH knockdown altered brain energy metabolism, resulting in a decline in ATP levels and an increase in IDH activity. …”
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    IDH knockdown alters foraging behavior in the termite Odontotermes formosanus in different social contexts
  8. 348
    “…Conclusion: TMT has not appeared as a statistically independent prognostic marker in this cohort of patients with newly diagnosed IDH-wildtype glioblastoma.…”
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    Newly Diagnosed IDH-Wildtype Glioblastoma and Temporal Muscle Thickness: A Multicenter Analysis
  9. 349
    “…In this report, we investigate the treatment and prognosis of the patients with LrGG harboring IDH mutations in our institutions. Methods:We retrospectively review primary treatments and their prognosis for LrGG patients with IDH mutation since 2003. …”
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    ACT-5 Prognosis of IDH-mut lower-grade gliomas in Hokkaido University Hospital
  10. 350
    Publicado 2022
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    IDH-Mutated AML: Beyond Enasidenib and Ivosidenib Monotherapy: Highlights From SOHO 2021
  11. 351
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    IDH-mutant astrocytoma with EGFR amplification—Genomic profiling in four cases and review of literature
  12. 352
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    Cup‐like blasts in acute myeloid leukaemia with NPM1 and IDH2 mutations
  13. 353
    “…IDH2 mutations promote progression in acute myeloid leukemia, glioma and other diseases. …”
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    IDH2: A novel biomarker for environmental exposure in blood circulatory system disorders
  14. 354
    “…The present study aims to analyze the prognostic potential of EGFL7 in GBM isocitrate dehydrogenase (IDH)-wildtype, using immunohistochemistry and in silico approaches. …”
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    EGFL7 expression profile in IDH-wildtype glioblastomas is associated with poor patient outcome
  15. 355
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    PB1783: IDENTIFICATION OF RAMAN SPECTROSCOPIC SIGNATURE OF IDH MUTATIONS IN AML IN VITRO MODEL
  16. 356
    “…However, the characteristics of isocitrate dehydrogenase (IDH) wild type (wt) (IDHwt), pTERTwt glioblastomas are not well known. …”
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    Molecular landscape of IDH ‐wild type, pTERT ‐wild type adult glioblastomas
  17. 357
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    Role of the tumor microenvironment in shaping IDH-wildtype glioma plasticity, and potential therapeutic strategies
  18. 358
    por Kashani, Elham, Vassella, Erik
    Publicado 2022
    “…This review has a special focus on “glioblastoma, IDH wild-type” (GBM) tumors, for which the therapy options have limited efficacy, and tumor relapse is inevitable.…”
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    Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype
  19. 359
    “…BACKGROUND: Isocitrate dehydrogenase (IDH) is an appealing target for anticancer therapy, and IDH (IDH1/2) inhibitors have been approved for targeted therapy of acute myeloid leukemia (AML) and Cholangiocarcinoma. …”
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    Molecular and clinical characteristics of IDH mutations in Chinese NSCLC patients and potential treatment strategies
  20. 360
    “…BACKGROUND AND OBJECTIVE: Determination of isocitrate dehydrogenase (IDH) 1/2 mutational status is crucial for a glioma diagnosis. …”
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    Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas
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