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  1. 361
    “…Methods: A literature review was performed on the PubMed, MEDLINE and Scopus databases using the following search items: “radiomics and glioma”, “radiomics and glioblastoma”, “radiomics and glioma and IDH”, “radiomics and glioma and TERT promoter”, “radiomics and glioma and EGFR”, “radiomics and glioma and chromosome”. …”
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    Forecasting Molecular Features in IDH-Wildtype Gliomas: The State of the Art of Radiomics Applied to Neurosurgery
  2. 362
    “…BACKGROUND: Although temozolomide (TMZ) has been used as a standard adjuvant chemotherapeutic agent for primary glioblastoma (GBM), treating isocitrate dehydrogenase wild-type (IDH-wt) cases remains challenging due to intrinsic and acquired drug resistance. …”
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    Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma
  3. 363
    “…Based on that, isocitrate dehydrogenase 1 (IDH1) wild-type HGGs are more aggressive than IDH1 mutant-type ones, we hypothesized that patients with IDH1 wild-type HGG would exhibit more severe NCF deficits than their IDH1 mutant counterparts. …”
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    Association between preoperative neurocognitive status and IDH1 mutation status in high-grade gliomas
  4. 364
    “…RESULTS: IDH1 gene mutation occurred in 82 cases, IDH2 gene mutation occurred in five cases and TERT promoter mutation occurred in 54 cases. …”
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    Relationship between IDH1/2 and TERT promoter mutation and the prognosis of human glioma patients
  5. 365
    “…How safe and effective is PRT for IDH-mutated glioma WHO grade 2 and 3? METHODS: We analyzed 194 patients diagnosed with IDH-mutated WHO grade 2 (n = 128) and WHO grade 3 (n = 66) glioma who were treated with PRT from 2010 to 2020. …”
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    Analysis of safety and efficacy of proton radiotherapy for IDH-mutated glioma WHO grade 2 and 3
  6. 366
    “…In IDH mutant gliomas, NFKBIA deletions are common in tumors with a clinical course similar to that of IDH wild-type tumors. …”
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    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
  7. 367
    “…OBJECTIVE: To investigate the value of a nomogram based on multiparametric and multiregional MR images to predict Isocitrate Dehydrogenase-1 (IDH1) gene mutations in glioma. DATA AND METHODS: The authors performed a retrospective analysis of 110 MR images of surgically confirmed pathological gliomas; 33 patients with IDH1 gene Mutation (IDH1-M) and 77 patients with Wild-type IDH1 (IDH1-W) were divided into training and validation sets in a 7:3 ratio. …”
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    Prediction of IDH1 gene mutation by a nomogram based on multiparametric and multiregional MR images
  8. 368
    “…Acute myeloid leukemia (AML) is characterized by uncontrolled proliferation of poorly differentiated myeloid cells, with a heterogenous mutational landscape. Mutations in IDH1 and IDH2 are found in 20% of the AML cases. …”
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    Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML
  9. 369
    “…Isocitrate dehydrogenase (IDH) mutations are found in 20% of acute myeloid leukemia (AML) patients. …”
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    Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells
  10. 370
    “…Methods: Patients were included who had newly diagnosed, histologically confirmed isocitrate dehydrogenase (IDH)–wild-type glioblastoma with available TSPO PET before either normofractionated radiotherapy combined with temozolomide or hypofractionated radiotherapy. …”
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    Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma
  11. 371
    “…Chondrosarcomas are the most common malignancy of cartilage and are associated with somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes. Somatic IDH mutations are also found in its benign precursor lesion, enchondromas, suggesting that IDH mutations are early events in malignant transformation. …”
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    Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
  12. 372
    “…OBJECTIVE: This study aims to assess the value of biomarker based radiomics to predict IDH mutation in gliomas. The patient cohort consists of 160 patients histopathologicaly proven of primary glioma (WHO grades 2–4) from 3 different centers. …”
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    Investigating the value of radiomics stemming from DSC quantitative biomarkers in IDH mutation prediction in gliomas
  13. 373
    “…CONCLUSION: The IDH1 mutation is expected to be almost mutually exclusive with EGFR amplification, so glioma cells with IDH1 mutations seem to represent a new group of tumour cells, which cannot be readily analysed in vitro because of their elimination. …”
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    Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions
  14. 374
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    Integration sites of the HTLV-1 provirus in host human genome in the IDH patients with monoclonal integration
  15. 375
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    Expression of the HBZ and tax genes of HTLV-1in infective dermatitis associated with HTLV-I (IDH)
  16. 376
    “…This analysis allowed us to define two highly recurrent genetic signatures in gliomas: IDH1/ATRX (I-A) and IDH1/CIC/FUBP1 (I-CF). Patients with I-CF gliomas had a significantly longer median overall survival (96 months) than patients with I-A gliomas (51 months) and patients with gliomas that did not harbor either signature (13 months). …”
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    Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
  17. 377
    “…Isocitrate dehydrogenase (IDH) genes 1 and 2 are frequently mutated in acute myeloid leukaemia (AML), low-grade glioma, cholangiocarcinoma (CC) and chondrosarcoma (CS). …”
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    Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2
  18. 378
    “…BACKGROUND AND OBJECTIVE: IDH1 (isocitrate dehydrogenase 1) is a potential biomarker and drug target. …”
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    An Analysis of the Prognostic Value of IDH1 (Isocitrate Dehydrogenase 1) Mutation in Polish Glioma Patients
  19. 379
    “…BACKGROUND: Recent studies have identified prevalent isocitrate dehydrogenase 1 (IDH1) codon 132 mutations (p.R132) in gliomas and acute myeloid leukemia (AML). …”
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    IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma
  20. 380
    “…Consistent with the observation in cells, analysis of TCGA data indicated a significant increase in PC expression in mutant IDH-expressing human glioma samples compared to wild-type IDH. …”
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    Glioma Cells with the IDH1 Mutation Modulate Metabolic Fractional Flux through Pyruvate Carboxylase
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