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  1. 1161
    “…OBJECTIVES: Little is known about the prevalence and impact of isolated diastolic hypertension (IDH) in northeast China. We aimed to investigate the current epidemiology of IDH and to illustrate whether IDH accounted for cardiovascular disease (CVD) mortality. …”
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    Prevalence of isolated diastolic hypertension and the risk of cardiovascular mortality among adults aged 40 years and older in northeast China: a prospective cohort study
  2. 1162
    “…PURPOSE: Isocitrate dehydrogenase 1 (IDH1) mutations are associated with improved survival in gliomas. …”
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    Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation
  3. 1163
    “…These tumours are characterised by the presence and absence of IDH1 and IDH2 mutations, and recently, TERT promoter alterations have been reported in around 20% of cases. …”
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    A genetic model for central chondrosarcoma evolution correlates with patient outcome
  4. 1164
    “…The active form of BlIDH was an 83-kDa homodimer. Kinetic analysis showed BlIDH was a NADP(+)-dependent IDH (NADP-IDH), with a 567- and 193-fold preference for NADP(+) over NAD(+) in the presence of Mg(2+) and Mn(2+), respectively. …”
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    Biochemical Characterization and Complete Conversion of Coenzyme Specificity of Isocitrate Dehydrogenase from Bifidobacterium longum
  5. 1165
    “…OBJECTIVES: To explore the characteristics of IDH and TERT promoter mutations in gliomas in Chinese patients. …”
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    Characteristics of the isocitrate dehydrogenase gene and telomerase reverse transcriptase promoter mutations in gliomas in Chinese patients
  6. 1166
    “…The linear concentration ranges obtained for the molecular recognition and quantification of IDH1 and IDH2 were: IDH1 (1 × 10(−5)–1 × 10(2) ng mL(−1)) and IDH2 (5 × 10(−8) − 5 × 10(2) ng mL(−1)). …”
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    Stochastic Microsensors Based on Carbon Nanotubes for Molecular Recognition of the Isocitrate Dehydrogenases 1 and 2
  7. 1167
    “…Background: Intradialytic hypotension (IDH) is a critical pathological condition associated with all-cause mortality in patients undergoing hemodialysis (HD). …”
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    Differences between Hepatic and Cerebral Regional Tissue Oxygen Saturation at the Onset of Intradialytic Hypotension
  8. 1168
    “…Recent whole-genome studies revealed novel GBM prognostic biomarkers such as mutations in metabolic enzyme IDH—isocitrate dehydrogenases (IDH1 and IDH2). The distinctive mutation IDH1 R132H was uncovered to be a strong prognostic biomarker for glioma patients. …”
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    Isocitrate Dehydrogenase-1 Mutations as Prognostic Biomarker in Glioblastoma Multiforme Patients in West Bohemia
  9. 1169
    “…METHODS: The involvement of IDH2 in radiotherapeutic efficacy in ESCC was investigated in vitro and vivo by IDH2 knockdown. …”
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    Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling
  10. 1170
    “…Unlike other bacterial homodimeric NAD-IDHs, PtIDH1 activity was allosterically regulated by the isocitrate. …”
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    Biochemical Characterization and Crystal Structure of a Novel NAD(+)-Dependent Isocitrate Dehydrogenase from Phaeodactylum tricornutum
  11. 1171
    “…Mutations in the isocitrate dehydrogenase gene (IDH1) are involved in the progression of tumors. …”
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    Integrative Multiomics Evaluation of IIDH1 Metabolic Enzyme as a Candidate Oncogene That is Correlated with Poor Prognosis and Immune Infiltration in Prostate Adenocarcinoma
  12. 1172
    “…The goal of our study was to systematically investigate the association between TMB, expressed neoantigens, and the tumor immune microenvironment in IDH-mutant and IDH-wildtype gliomas, which are two types of biologically distinct gliomas. …”
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    Tumor Mutation Burden, Expressed Neoantigens and the Immune Microenvironment in Diffuse Gliomas
  13. 1173
    “…INTRODUCTION: The function of the autonomic nervous system (ANS) is crucial in the development of intradialytic hypotension (IDH). This study introduced the entropy of heart rate variability (HRV) and skin sympathetic nerve activity (SKNA) to provide a complementary nonlinear and dynamic perspective for evaluating ANS function concerning IDH. …”
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    Evaluation of autonomic nervous system activity in intradialytic hypotension using entropy and skin sympathetic nerve activity
  14. 1174
    “…The influencing factors of UAS-IDH were LAS-IDH, surgical segment IDH, and HO while that of LAS-IDH were UAS-IDH and surgical segment IDH. …”
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    Radiological exploration on adjacent segments after total cervical disc replacement with Prodisc-C prosthesis
  15. 1175
    “…Intriguingly, AR regulates cytoplasmic isocitrate dehydrogenase 1 (IDH1), but not its mitochondrial counterparts IDH2 and IDH3. …”
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    Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer
  16. 1176
    “…RESULTS: According to the 2016 WHO classification, 124 cases of diffuse brain glioma were reclassified as follows: 10 oligodendroglioma, IDH(mut) and 1p/19q co-deleted; three anaplastic oligodendroglioma, IDH(mut) and 1p/19q co-deleted; 35 diffuse astrocytoma, IDH(mut), 11 diffuse astrocytoma, IDH(wt), not otherwise specified (NOS); 22 anaplastic astrocytoma, IDH(mut), eight anaplastic astrocytoma, IDH(wt), NOS; and 35 glioblastoma, IDH(wt), NOS, respectively. …”
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    Reclassification of Mongolian Diffuse Gliomas According to the Revised 2016 World Health Organization Central Nervous System Tumor Classification
  17. 1177
    “…The demonstration of new factors such as isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) mutations will be important in the diagnosis and treatment. …”
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    Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients
  18. 1178
    “…BACKGROUND: The expression of 5-hydroxymethylcytosine (5-hmC) and isocitrate dehydrogenase 2 (IDH2) is frequently downregulated in numerous cancers. 5-hmC and IDH2 expression in hepatocellular carcinoma (HCC) has yet to be determined. …”
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    High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma
  19. 1179
    “…RESULTS: Among the 191 patients, IDH occurred in 32. AACS was higher in the IDH group compared with the no-IDH group (8.4 ± 6.0 vs. 4.9 ± 5.2, respectively; P = 0.001). …”
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    The relationship between intradialytic hypotension and vascular calcification in hemodialysis patients
  20. 1180
    “…Some authors have suggested that in the fetus, neonate and infant, intradural hemorrhage (IDH) is relatively common and often presents alongside subdural hemorrhage (SDH). …”
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    Frequency of macroscopic intradural hemorrhage with and without subdural hemorrhage in early childhood autopsies
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