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  1. 1201
    “…Background: Intradialytic hypotension (IDH) is a frequent and grave complication of hemodialysis (HD). …”
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    Dynamic Echocardiographic Assessments Reveal Septal E/e’ Ratio as Independent Predictor of Intradialytic Hypotension in Maintenance for Hemodialysis Patients with Preserved Ejection Fraction
  2. 1202
    “…In 6 of the patients IDH status was unknown. Among 8 grade 2 and 3 tumors with IDH mutant, 2 had loss of ATRX and 6 had ATRX retained. …”
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    CLRM-05 ADAPTATION OF NEW CLASSIFICATION OF ASTROCYTOMA IN LOW AND MIDDLE INCOME COUNTRY- HOW SMOOTH IS THE ROAD AHEAD?
  3. 1203
    “…Astrocytic gliomas of World Health Organization (WHO) grades III or IV (36 IDH‐mutant and 36 IDH‐wild‐type) from 72 patients were included in this study. …”
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    The presence of TIM‐3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status
  4. 1204
    “…BACKGROUND: The metabolic enzyme isocitrate dehydrogenase 1 (IDH1) belonging to β-decarboxylase dehydrogenase family has been identified as a tumor suppressor. …”
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    Withaferin A suppresses skin tumor promotion by inhibiting proteasome-dependent isocitrate dehydrogenase 1 degradation
  5. 1205
    “…We further observe enhanced wild-type IDH1 and IDH2 expression in two clusters, which coincide with hypoxia and Nestin expression, marking a stem-cell like niche. …”
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    MEDB-70. Metabolism mediated radiation resistance in MYC-driven Medulloblastoma
  6. 1206
    “…[Image: see text] Mutations of isocitrate dehydrogenase 1 (IDH1) are frequently found in certain cancers such as glioma. …”
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    Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Synthesis, Structure–Activity Relationship, and Selective Antitumor Activity
  7. 1207
    “…INTRODUCTION: Intradialytic hypotension (IDH) is a major complication of hemodialysis, with a prevalence of about 25% during hemodialysis sessions, causing increased morbidity and mortality. …”
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    Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis
  8. 1208
    “…The expression of S. mutans IDH (SmIDH) may restore the wild-type phenotype of the icd-defective strain on minimal medium without glutamate. …”
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    Isocitrate Dehydrogenase from Streptococcus mutans: Biochemical Properties and Evaluation of a Putative Phosphorylation Site at Ser102
  9. 1209
    “…Isocitrate dehydrogenase 1 (IDH1) mutation has been reported to be associated with an increased overall survival in patients with glioma in a number of studies. …”
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    Mechanisms underlying the biological changes induced by isocitrate dehydrogenase-1 mutation in glioma cells
  10. 1210
    “…MfIDH exhibited a cofactor-dependent pH-activity profile. …”
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    Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus Flagellatus
  11. 1211
    “…In the present study, we report that the antigrowth effect of JQ1 differs among ICC cells and IDH1 mutation sensitizes ICC cells to JQ1. RBE cells harboring IDH1 mutation was more sensitive to JQ1 than HuCCT1 or HuH28 cells with wild‐type IDH1. …”
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    Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1
  12. 1212
    “…BACKGROUND: Critical limb ischemia (CLI) and intradialytic hypotension (IDH) are common complications in patients on hemodialysis (HD). …”
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    Intradialytic hypotension is an important risk factor for critical limb ischemia in patients on hemodialysis
  13. 1213
    “…BACKGROUND: Intradialytic hypotension (IDH) is a common complication in maintaining hemodialysis (MHD) patients. …”
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    Pro-inflammatory cytokines as potential predictors for intradialytic hypotension
  14. 1214
    “…Here, we show that mutational status of IDH1 is linked to 5-ALA fluorescence. Using genetically engineered malignant glioma cells harboring wild type (U87MG-IDH1(WT)) or mutant (U87MG-IDH1(R132H)) IDH1, we demonstrated a lag in 5-ALA metabolism and accumulation of protoporphyrin IX (PpIX) in U87MG-IDH1(R132H) cells. …”
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    Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas
  15. 1215
    “…Reductive glutamine metabolism was highly dependent on cytosolic isocitrate dehydrogenase-1 (IDH1), because the activity was suppressed in cells homozygous null for IDH1 or treated with an IDH1 inhibitor. …”
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    Reductive carboxylation supports redox homeostasis during anchorage-independent growth
  16. 1216
    “…Intriguingly, the effects of Cd(2+) on the activity of IDH are both positive and negative, and to understand the molecular basis, we determined the crystal structure of NADP(+)-dependent cytosolic IDH in the presence of Cd(2+). …”
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    NADP(+)-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione
  17. 1217
    “…Intradialytic hypotension (IDH) is a frequent and serious complication of chronic haemodialysis, linked to adverse long-term outcomes including increased cardiovascular and all-cause mortality. …”
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    An update review of intradialytic hypotension: concept, risk factors, clinical implications and management
  18. 1218
    “…Among the various NAD(+)-specific MaIDH1/2/3 overexpression, NAD(+)-MaIDH3 reduced total lipid content by 12.5%, whereas overexpression NAD(+)-MaIDH1 and NAD(+)-MaIDH2 had no effect on fatty acid content. …”
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    Characterization of NAD(+)/NADP(+)-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation
  19. 1219
    “…BACKGROUND: To investigate the distribution and characteristics of the lumbar intervertebral disc height (IDH) in asymptomatic Asian population and to determine whether the lumbar IDH is related to the lumbar spine sagittal alignment. …”
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    Correlation between lumbar intervertebral disc height and lumbar spine sagittal alignment among asymptomatic Asian young adults
  20. 1220
    “…However, the molecular mechanisms of how IDH2 mutations induce carcinogenesis remain unclear. …”
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    Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2
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