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  1. 1301
    “…The IDH1/2 gene mutations, ATRX loss/mutation, 1p/19q status, and MGMT promoter methylation are increasingly used as prognostic or predictive biomarkers of gliomas. …”
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    Potential Role of Methylation Marker in Glioma Supporting Clinical Decisions
  2. 1302
    “…To investigate the regulatory mechanism of mIDH2 (mouse mitochondrial IDH2), we used lysine-to-glutamine (KQ) mutants to mimic acetylated lysines and screened 15 KQ mutants. …”
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    Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics
  3. 1303
    “…INTRODUCTION: Intra-dialytic hypotension (IDH) is a common complication of haemodialysis that impacts negatively on the patient's quality of life and can induce serious cardiovascular events. …”
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    Prevalence and risk factors of intra-dialytic hypotension: a 5 year retrospective report from a single Nigerian Centre
  4. 1304
    “…Gliomas demonstrate epigenetic dysregulation exemplified by the Glioma CpG Island Methylator Phenotype (G-CIMP) seen in IDH1 mutant tumors. 5-Hydroxymethylcytosine (5hmC) is implicated in glioma pathogenesis; however, its role in IDH1 mutant gliomas is incompletely understood. …”
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    5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma
  5. 1305
    “…We present a case of the T2-FLAIR mismatch sign in glioblastoma, isocitrate dehydrogenase (IDH)-wild type. The T2-FLAIR mismatch sign is known as a highly specific imaging finding of astrocytoma, IDH-mutant. …”
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    The T2-FLAIR mismatch sign in glioblastoma, isocitrate dehydrogenase wild-type A case report
  6. 1306
    “…With respect to the distribution by histology, we found that gliomas concurrent with IDH-mutant and 1p/19q-codeleted or with single IDH-mutant were mainly distributed in frontal lobe, while those with IDH-wildtype were dominant in temporal lobe. …”
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    Impact of epidemiological characteristics of supratentorial gliomas in adults brought about by the 2016 world health organization classification of tumors of the central nervous system
  7. 1307
    “…However, the effect of IDH1 mutation on the combination of Bev and TMZ is unknown. …”
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    Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma
  8. 1308
    “…OBSERVATIONS: The authors present the case of a 29-year-old male with an IDH1-mutant, World Health Organization grade III anaplastic astrocytoma in the dorsal medulla, and they provide a review of the available literature on adult IDH-mutant brainstem glioma. …”
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    Adult isocitrate dehydrogenase–mutant brainstem glioma: illustrative case
  9. 1309
    “…Intramural Duodenal Haematoma (IDH) is an uncommon complication of blunt abdominal trauma. …”
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    Laparoscopic drainage of an intramural duodenal haematoma: a novel technique and review of the literature
  10. 1310
    “…METHODS: This multicenter study included 327 patients with IDH-mutant or IDH-wildtype glioblastoma in the 2016 World Health Organization classification who preoperatively underwent MRI. …”
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    Importance of Age and Noncontrast-Enhancing Tumor as Biomarkers for Isocitrate Dehydrogenase–Mutant Glioblastoma: A Multicenter Study
  11. 1311
    “…Paradoxically, TMZ did not appear to benefit patients with IDH-wildtype gliomas, regardless of MGMT promoter status. …”
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    MGMT promoter methylation in 1p19q-intact gliomas
  12. 1312
    “…ATRA treatment specifically decreased cell viability and induced apoptosis of mutant IDH1 blasts in vitro. ATRA also reduced tumor burden of mutant IDH1 AML cells xenografted in NOD–Scid–IL2rγ(null) mice and markedly increased overall survival, revealing a potent antileukemic effect of ATRA in the presence of IDH1 mutation. …”
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    Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
  13. 1313
    por Laba, Pingcuo, Wang, Jianfeng, Zhang, Jin
    Publicado 2018
    “…BACKGROUND: The purpose of this study was to investigate the role of isocitrate dehydrogenase 1 (IDH1) expression on prognosis of patients with clear cell renal cell carcinoma (ccRCC) following nephrectomy. …”
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    Low level of isocitrate dehydrogenase 1 predicts unfavorable postoperative outcomes in patients with clear cell renal cell carcinoma
  14. 1314
    “…The aim of the present study was to identify potential molecular mechanisms and therapeutic targets in regards to isocitrate dehydrogenase 2 (IDH2) R140Q-mutated acute myeloid leukemia (AML). …”
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    Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia
  15. 1315
    “…Based on the 2016 WHO classification, 80 patients (52.3%) had diffuse astrocytoma, IDH-mutant; 45 (29.4%) had oligodendroglioma, IDH-mutant and 1p/19q-codeleted (ODG); and 28 (18.3%) had diffuse astrocytoma, IDH-wildtype. …”
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    Extent of resection and molecular pathologic subtype are potent prognostic factors of adult WHO grade II glioma
  16. 1316
    “…BACKGROUND: To compare the efficacies of univariate and radiomics analyses of amide proton transfer weighted (APT(W)) imaging in predicting isocitrate dehydrogenase 1 (IDH1) mutation of grade II/III gliomas. METHODS: Fifty-nine grade II/III glioma patients with known IDH1 mutation status were prospectively included (IDH1 wild type, 16; IDH1 mutation, 43). …”
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    Amide Proton Transfer Imaging in Predicting Isocitrate Dehydrogenase 1 Mutation Status of Grade II/III Gliomas Based on Support Vector Machine
  17. 1317
    “…RESULT: In the integrated diagnosis, 11 astrocytomas and 17 anaplastic astrocytomas were diagnosed as “IDH-mutant”, while 14 astrocytomas and 29 anaplastic astrocytomas were diagnosed as “IDH-wild”. …”
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    NI-06 MOLECULAR DIAGNOSIS, 11C-METHIONINE UPTAKE AND PROGNOSIS IN GRADE 2 AND 3 GLIOMAS
  18. 1318
    “…First, all 155 patients were assigned to three molecular groups according to the 2016 WHO classification system: (1) oligodendroglioma, IDH-mutant and 1p19q co-deleted (n = 81); (2) astrocytoma, IDH-mutant and 1p19q non-codeleted (n = 54); (3) astrocytoma, IDH-wildtype (n = 20). …”
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    Extent and prognostic value of MGMT promotor methylation in glioma WHO grade II
  19. 1319
    “…BACKGROUND: Patients with isocitrate dehydrogenase (IDH) mutant gliomas have been associated with longer survival time than those that are IDH wild-type. …”
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    Prognostic value of O(6)-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas
  20. 1320
    “…OBJECTIVE: Previously developed Intradialytic hypotension (IDH) prediction models utilize clinical variables with potential privacy protection issues. …”
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    Deep Learning Model for Predicting Intradialytic Hypotension Without Privacy Infringement: A Retrospective Two-Center Study
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