Mostrando 1,341 - 1,360 Resultados de 4,168 Para Buscar '"IDH"', tiempo de consulta: 0.34s Limitar resultados
  1. 1341
  2. 1342
    “…Lower grade glioma is classified based on genetic information of mutation of IDH1/2 gene and co-deletion of chromosome 1p19q. …”
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  3. 1343
    “…Diagnostic models were developed from real IDH-wild type (n = 80) with real IDH-mutant glioblastomas (n = 38), or with synthetic IDH-mutant glioblastomas, or augmented by adding both real and synthetic IDH-mutant glioblastomas. …”
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  4. 1344
    “…Participants were categorized as having normal blood pressure (BP), elevated BP, stage 1 IDH, stage 1 ISH, stage 1 SDH, stage 2 IDH, stage 2 ISH, and stage 2 SDH. …”
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  5. 1345
  6. 1346
  7. 1347
    “…BACKGROUND: Intradialytic hypotension (IDH) has been recognized as a serious and frequent complication during hemodialysis (HD) of end-stage renal disease (ESRD) patients, but the effect of asymptomatic IDH on cardiac troponin I (cTnI) levels is not definitively elucidated. …”
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  8. 1348
  9. 1349
    “…And following parameters were measured and evaluated: intervertebral disk height (IDH), the ratio of IDH(IDH(L4-5/L3-4)), initial IDH of L4-5(iIDH(L4-5)) in the DLSS group, disk degeneration (DD), cartilaginous endplate failure (CEF), Modic changes, the thickness of ligamentum flavum (LF), range of intervertebral motion (ROM), facet joint opening (FJO), facet joint angle (FJA), the standard cross-sectional area (SCSA) of the multifidus, erector spinae, and psoas major muscles. …”
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  10. 1350
    por Ye, Dan, Guan, Kun-Liang, Xiong, Yue
    Publicado 2018
    “…Therapies are being developed to treat IDH-mutant cancers by targeting either the mutant IDH enzymes directly or the pathways sensitized by 2-HG.…”
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  11. 1351
    por Keum, Young-Sam, Choi, Bu Young
    Publicado 2015
    “…The present review article briefly discusses the important findings that highlight the molecular mechanisms of IDH1/2 mutations in cancer and provides a current status for development of selective mutant IDH1/2 chemical inhibitors. …”
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  12. 1352
  13. 1353
    “…SIMPLE SUMMARY: IDH-mutant low-grade gliomas (LGG) are slow-growing glial cell-derived tumors of the central nervous system (CNS) that predominantly manifest in young adults and often show malignant transformation. …”
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  14. 1354
  15. 1355
    “…This assay was evaluated using IDH1-WT or IDH1-R132H mutant synthetic DNA, wild-type or IDH1-R132H mutant U87MG cell lysates, and tumor lysates from archived patient samples in which the IDH1 status was previously determined using immunohistochemistry (IHC). …”
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  16. 1356
  17. 1357
  18. 1358
    “…Three pathways were identified to be associated with IDH mutation status. Within arginine and proline metabolism, levels of intermediate metabolites in creatine pathway were all significantly lower in IDH mutation positive than in negative patients, suggesting an increased activity of creatine pathway in IDH mutation positive tumors. …”
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  19. 1359
    “…While astrocytomas and IDH-mutant (secondary) glioblastomas are characterized by the mutational status of IDH, TP53, and ATRX, oligodendrogliomas have a 1p/19q codeletion and mutations in IDH, CIC, FUBP1, and the promoter region of telomerase reverse transcriptase (TERTp). …”
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  20. 1360
    “…However, the odds of having IDH decreased with increasing age. Females has lower odds of having SDH and IDH compared with male participants. …”
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