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  1. 1361
    “…In IDH-mutant gliomas, greater extent of resection was achieved than in IDH-wildtype tumors. …”
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    Interrelationships between molecular subtype, anatomical location, and extent of resection in diffuse glioma: a systematic review and meta-analysis
  2. 1362
    “…Materials and Methods: 89 patients with treated diffuse glioma with different molecular subtypes (IDH wild type (Astro-IDH(wt)), IDH mutant astrocytomas (Astro-IDH(mut)) and oligodendrogliomas), and tumor-suspect lesions on post-treatment follow-up imaging were classified into two outcome groups (PD or PsP) retrospectively by histopathology or clinical follow-up. …”
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    Dynamic Susceptibility Perfusion Imaging for Differentiating Progressive Disease from Pseudoprogression in Diffuse Glioma Molecular Subtypes
  3. 1363
    “…The aim of this study was to investigate associations between age-dependent variations in isolated systolic/diastolic hypertension (ISH/IDH) with target organ damage in chronic kidney disease (CKD). …”
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    Effect of age and isolated systolic or diastolic hypertension on target organ damage in non-dialysis patients with chronic kidney disease
  4. 1364
    “…The GMV of the entire contralesional insula was also larger in insular glioma patients with IDH mutation than in patients with wild-type IDH. …”
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    Contralesional Structural Plasticity in Different Molecular Pathologic Subtypes of Insular Glioma
  5. 1365
    “…Moreover, NAD-IDH regulatory subunits β and γ are exclusive to metazoans, arising in the Mesoproterozoic. …”
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    Evolution of a key enzyme of aerobic metabolism reveals Proterozoic functional subunit duplication events and an ancient origin of animals
  6. 1366
    “…According to the genomic profile, four genetic subgroups could be distinguished: (1) ID(wt)/cIMPACT-NOW 3 (n = 270); (2) IDH(wt)/cIMPACT-NOW 3 negative (= 10); (3) IDH(mut)/cIMPACT-NOW 3 (n = 16); and 4) IDH(mut)/cIMPACT-NOW 3 negative (n = 17). …”
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    Optimizing the risk stratification of astrocytic tumors by applying the cIMPACT-NOW Update 3 signature: real-word single center experience
  7. 1367
    “…BACKGROUND: Fluid removal during dialysis, also known as ultrafiltration (UF), leads to intradialytic hypotension (IDH) in a significant number of patients treated with hemodialysis (HD) and is associated with an increase in morbidity and mortality. …”
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    Ultrafiltration biofeedback guided by blood volume monitoring to reduce intradialytic hypotensive episodes in hemodialysis: study protocol for a randomized controlled trial
  8. 1368
    “…Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2) are important drivers of cancer, including central nervous system (CNS) tumors. …”
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    Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors
  9. 1369
    “…In additional analyses, IDH-mutated and IDH-wildtype patients were compared. …”
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    Diffusion Tensor Imaging Reveals Microstructural Heterogeneity of Normal-Appearing White Matter and Related Cognitive Dysfunction in Glioma Patients
  10. 1370
    “…CONCLUSION: Our study suggests that the stem cell origin of IDH wild-type and IDH mutated low-grade gliomas may be different.…”
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    Is the anatomical distribution of low-grade gliomas linked to regions of gliogenesis?
  11. 1371
    por Komori, Takashi
    Publicado 2019
    “…The grading scheme for adult IDH-mutant as well as wild-type gliomas should therefore be revised in the next WHO update.…”
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    S4-KL-1 UPDATE OF WHO2016 CLASSIFICATION OF ADULT DIFFUSE GLIOMAS
  12. 1372
    “…Pathological diagnosis was DMG, H3K27M-mutant in 3 patients, glioblastoma, IDH-mutant in 1, anaplastic astrocytoma, IDH-wildtype in 4, diffuse astrocytoma, IDH-mutant in 1, and diffuse astrocytoma, IDH-wildtype in 1. …”
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    DIPG-17. BIOPSY-PROVEN DIFFUSE MIDLINE GLIOMA IN ADOLESCENTS AND YOUNG ADULTS
  13. 1373
    “…To what extent dysautonomia may contribute to the occurrence of IDH remains elusive. We sought to investigate the clinical utility of Sudocan(®), a device that quantifies dysautonomia, in the prediction of IDH. …”
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    Electrochemical skin conductance by Sudoscan(®): a new tool to predict intradialytic hypotension
  14. 1374
    “…The functionality and the contribution of DC to the IDH-mutant tumor microenvironment (TME) remains unclear. …”
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    Dysfunctional dendritic cells limit antigen-specific T cell response in glioma
  15. 1375
    “…BACKGROUND: 2-hydroxy-glutarate (2HG) is a metabolite that accumulates in isocitrate dehydrogenase (IDH)-mutated gliomas and can be detected noninvasively using MR spectroscopy. …”
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    Accurate prediction of isocitrate dehydrogenase -mutation status of gliomas using SLOW-editing magnetic resonance spectroscopic imaging at 7 T MR
  16. 1376
    “…We also observed that patients with DNMT3A (mut) IDH1/IDH2 (mut) had higher platelet counts (p = 0.009) and a lower BM blast percentage (p = 0.040) than those with DNMT3A (wt) IDH1/IDH2 (mut). …”
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    The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia
  17. 1377
    “…IDH1 mutations were mutually exclusive with H3F3A mutations. …”
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    Genetic and immune features of resectable malignant brainstem gliomas
  18. 1378
    “…Mutational analysis of IDH1 and TERT promoter mutations was performed by Sanger sequencing. …”
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    Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylation
  19. 1379
    “…The characterizations of IDH mutations in the glioma included IDH1 mutation (p.R132H) and IDH2 mutation (p.R172K). …”
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    Next-Generation Sequencing Analysis of ctDNA for the Detection of Glioma and Metastatic Brain Tumors in Adults
  20. 1380
    “…Ivosidenib is an oral inhibitor of the mutant isocitrate dehydrogenase 1 (IDH1) enzyme, approved for treatment of IDH1-mutant (mIDH1) acute myeloid leukemia (AML). …”
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    Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
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