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1521por Tommasini-Ghelfi, Serena, Murnan, Kevin, Kouri, Fotini M., Mahajan, Akanksha S., May, Jasmine L., Stegh, Alexander H.“…Cancer-associated mutations in IDH1 and IDH2 represent one of the most comprehensively studied mechanisms of IDH pathogenic effect. …”
Publicado 2019
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1522por Dan, Xie, Mushi, Zhang, Baili, Wang, Han, Lin, Enqi, Wu, Huanhu, Zhao, Shuchun, Li“…PSM was also used to match six IDH patients with six controls and to match 35 cases of SH with 35 controls. …”
Publicado 2019
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1523por Wu, Wendy Yi-Ying, Johansson, Gunnar, Wibom, Carl, Brännström, Thomas, Malmström, Annika, Henriksson, Roger, Golovleva, Irina, Bondy, Melissa L., Andersson, Ulrika, Dahlin, Anna M., Melin, Beatrice“…Second, variants in CDKN2B-AS1, EGFR, and RTEL1 were associated with IDH-wildtype glioma. Third, variants in CCDC26 (the 8q24 locus), C2orf80 (close to IDH), LRIG1, PHLDB1, ETFA, MAML2 and ZBTB16 were associated with IDH-mutant glioma. …”
Publicado 2019
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1524por Mellai, Marta, Annovazzi, Laura, Bisogno, Ilaria, Corona, Cristiano, Crociara, Paola, Iulini, Barbara, Cassoni, Paola, Casalone, Cristina, Boldorini, Renzo, Schiffer, Davide“…Results: NG2/CSPG4 was frequently expressed in IDH-mutant/1p19q-codel oligodendrogliomas (59.1%) and IDH-wild type GBs (40%) and rarely expressed in IDH-mutant or IDH-wild type astrocytomas (14.3%). …”
Publicado 2020
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1525“…The three major diagnostic entities of adult diffuse gliomas are as follows: (1) astrocytoma, IDH-mutant; (2) oligodendroglioma, IDH-mutant and 1p/19q-codeleted; and (3) glioblastoma, IDH-wildtype. …”
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1526“…Intramyocardial dissecting hematoma (IDH) is a rare and very dangerous complication of myocardial infarction (MI) and percutaneous intervention. …”
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1527“…Triglyceride levels were associated with IDH in U.S. adults (1.94 [1.43,2.63]).…”
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1528por Dao Trong, Philip, Jungwirth, Gerhard, Unterberg, Andreas, Herold-Mende, Christel, Warta, Rolf“…SIMPLE SUMMARY: Patients diagnosed with isocitrate dehydrogenase (IDH)-mutated brain tumors frequently suffer from seizures, and the seizures were shown to promote tumor growth. …”
Publicado 2023
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1529por Kao, Hsiao-Wen, Liang, Der-Cherng, Wu, Jin-Hou, Kuo, Ming-Chung, Wang, Po-Nan, Yang, Chao-Ping, Shih, Yu-Shu, Lin, Tung-Huei, Huang, Yu-Hui, Shih, Lee-Yung“…Twenty gene mutations including class I, class II, class III of epigenetic regulators (IDH1, IDH2, TET2, DNMT3A, MLL-PTD, ASXL1, and EZH2), and class IV (tumor suppressor genes) were analyzed in 67 patients with AML-M0. …”
Publicado 2014
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1530por Hinrichs, Benjamin H., Newman, Scott, Appin, Christina L., Dunn, William, Cooper, Lee, Pauly, Rini, Kowalski, Jeanne, Rossi, Michael R., Brat, Daniel J.“…The additional IDH1 mutant tumor lacked 1p/19q co-deletion, harbored a TP53 mutation, and overall, demonstrated features most consistent with IDH mutant (secondary) GBM. …”
Publicado 2016
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1531por Tsai, Ming-Yen, Su, Yu-Jen, Ng, Hwee-Yeong, Chen, Shih-Yu, Huang, Yu-Chuen, Wu, Chien-Hsing, Chen, Yung-Hsiang“…INTRODUCTION: Intradialytic hypotension (IDH) is the most frequent complication of haemodialysis (HD) and may contribute to cardiovascular events and high mortality. …”
Publicado 2016
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1532por Im, Jung Ho, Hong, Je Beom, Kim, Se Hoon, Choi, Junjeong, Chang, Jong Hee, Cho, Jaeho, Suh, Chang-Ok“…Based on the 2016 WHO classification, 25/73 (34.2%) patients had anaplastic oligodendroglioma (AO), IDH-mutant and 1p/19q-codeleted; 11/73 (15.1%) patients had anaplastic astrocytoma, IDH-mutant; and 37/73 (50.7%) patients had anaplastic astrocytoma, IDH-wildtype. …”
Publicado 2018
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1533por Park, Samel, Kim, Wook-Joon, Cho, Nam-Jun, Choi, Chi-Young, Heo, Nam Hun, Gil, Hyo-Wook, Lee, Eun Young“…This study aimed to identify whether a new method using heart rate variability (HRV) could predict intradialytic hypotension (IDH) for one month in advance for patients undergoing prevalent hemodialysis. …”
Publicado 2019
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1534“…Cases in GSE16011 were divided into two groups according to IDH1 mutation status. Cases in TCGA-LGG were classified to subtypes according to histopathological results, IDH1 mutation status and 1p19q status. …”
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1535“…Objective: Salivary rare basaloid lesions, including cribriform type basal cell adenoma (cBCA), BCA with incomplete capsule (iBCA), sialoblastoma (SB), and intercalated duct hyperplasia (IDH), could easily be misdiagnosed as adenoid cystic carcinoma (AdCC). …”
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1536“…INTRODUCTION: Intradialytic hypotension (IDH) is a frequent and serious complication of maintaining haemodialysis (HD) patients and associated with subsequent cardiovascular events and higher mortality. …”
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1537por Chang, Xing, Zhang, Tian, Wang, Junyan, Liu, Yan, Yan, Peizheng, Meng, Qingyan, Yin, Yongtian, Wang, Shiyuan“…Additionally, TAC inhibited SIRT5 expression at the mitochondrial level and increased IDH2 succinylation. However, quercetin promoted the desuccinylation of IDH2 by increasing SIRT5 expression. …”
Publicado 2021
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1538por Libera, Laura, Ottini, Giorgia, Sahnane, Nora, Pettenon, Fabiana, Turri-Zanoni, Mario, Lambertoni, Alessia, Chiaravalli, Anna Maria, Leone, Federico, Battaglia, Paolo, Castelnuovo, Paolo, Uccella, Silvia, Furlan, Daniela, Facco, Carla, Sessa, Fausto“…In our cohort, 14 cases showed alterations in SWI/SNF complex or IDH2 genes, which were associated with a higher global DNA methylation level and worst prognosis. …”
Publicado 2021
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1539por Hagiwara, Akifumi, Tatekawa, Hiroyuki, Yao, Jingwen, Raymond, Catalina, Everson, Richard, Patel, Kunal, Mareninov, Sergey, Yong, William H., Salamon, Noriko, Pope, Whitney B., Nghiemphu, Phioanh L., Liau, Linda M., Cloughesy, Timothy F., Ellingson, Benjamin M.“…This study aimed to differentiate isocitrate dehydrogenase (IDH) mutation status with the voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and to discover biological underpinnings of the clusters. …”
Publicado 2022
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1540por Nakanishi, Koki, Daimon, Masao, Yoshida, Yuriko, Ishiwata, Jumpei, Sawada, Naoko, Hirokawa, Megumi, Kaneko, Hidehiro, Nakao, Tomoko, Mizuno, Yoshiko, Morita, Hiroyuki, Di Tullio, Marco R., Homma, Shunichi, Komuro, Issei“…Participants were categorized into four groups: normal BP, elevated BP, isolated diastolic hypertension (IDH), and systolic hypertension (SH). Among the 858 participants, 422 individuals had normal BP, 113 had elevated BP, 160 had IDH, and 163 had SH. …”
Publicado 2022
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