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1721“…Intramural duodenal hematoma (IDH) is a rare entity which is generally associated with trauma. …”
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1722por Kuo, Lu-Ting, Tsai, Shao-Yu, Chang, Cheng-Chi, Kuo, Kuang-Ting, Huang, Abel Po-Hao, Tsai, Jui-Chang, Tseng, Ham-Min, Kuo, Meng-Fai, Tu, Yong-Kwang“…Tumor DNA was analyzed for alterations in selected genetic loci (1p36, 9p22, 10q23–24, 17p13, 19q13, 22q12), isocitrate dehydrogenase 1 (IDH1), isocitrate dehydrogenase 2 (IDH2) and the CpG island methylation status of critical tumor-related genes (MGMT, P16, DAPK, PTEN, RASSF1A, Rb1). …”
Publicado 2013
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1723por Ghasimi, Soma, Wibom, Carl, Dahlin, Anna M., Brännström, Thomas, Golovleva, Irina, Andersson, Ulrika, Melin, Beatrice“…Thirteen well known genetic risk variants in TERT, EGFR, CCDC26, CDKN2A, CDKN2B,PHLDB1, TP53, and RTEL1 were selected for investigation of possible correlations with the glioma somatic markers: EGFR amplification, 1p/19q codeletion and protein expression of p53, Ki-67, and mutated IDH1. The CDKN2A/B risk variant, rs4977756, and the CDKN2B risk variant, rs1412829 were inversely associated (p = 0.049 and p = 0.002, respectively) with absence of a mutated IDH1, i.e., the majority of patients homozygous for the risk allele showed no or low expression of mutated IDH1. …”
Publicado 2016
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1724por Mall, Raghvendra, Cerulo, Luigi, Bensmail, Halima, Iavarone, Antonio, Ceccarelli, Michele“…When applied to detect the main differences between the networks of IDH-mutant and IDH-wild-type glioma tumors, it correctly selects sub-networks centered on important key regulators of these two different subtypes. …”
Publicado 2017
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1725por Bi, Chao, Liu, Mei, Rong, Weiqi, Wu, Fan, Zhang, Yang, Lin, Shengtao, Liu, Yunhe, Wu, Jianxiong, Wang, Liming“…RESULTS: Beclin-1, ARID1A, CA9 and IDH1 were highly expressed in ICC tumor tissues. …”
Publicado 2019
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1726por Jaber, Mohammed, Ewelt, Christian, Wölfer, Johannes, Brokinkel, Benjamin, Thomas, Christian, Hasselblatt, Martin, Grauer, Oliver, Stummer, Walter“…In multivariate analysis IDH status and fluorescence both independently predicted MTFS and OS. …”
Publicado 2019
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1727por Chen, Xiaojing, Barywani, Salim Bary, Hansson, Per-Olof, Rosengren, Annika, Thunström, Erik, Zhong, You, Ergatoudes, Constantinos, Mandalenakis, Zacharias, Caidahl, Kenneth, Fu, Michael“…Furthermore, those with high-normal BP, ISH-IDH, and SDH had a higher risk of CVD than those with optimal-normal BP. …”
Publicado 2020
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1728por Koper-Lenkiewicz, Olga Martyna, Kamińska, Joanna, Reszeć, Joanna, Dymicka-Piekarska, Violetta, Ostrowska, Halina, Karpińska, Maria, Matowicka-Karna, Joanna, Tylicka, Marzena“…Immunohistochemistry for IDH1-R132H was done on 5-microns–thick formalin-fixed, paraffin-embedded tumor sections with the use of antibody specific for the mutant IDH1-R132H protein. …”
Publicado 2020
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1729por Huang, Zhenxing, Lu, Changyu, Li, Gen, Li, Zhenye, Sun, Shengjun, Zhang, Yazhuo, Hou, Zonggang, Xie, Jian“…The combined prediction could enhance the discrimination of grading, IDH and TERT mutation, and also with a good fitness. …”
Publicado 2021
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1730por de Souza, Carlos Dornels Freire, de Oliveira, Denilson José, da Silva, Leonardo Feitosa, dos Santos, Camila Damasceno, Pereira, Monaliza Coelho, de Paiva, João Paulo Silva, Leal, Thiago Cavalcanti, Mariano, Renato de Souza, de Araújo, Amanda Karine Barros Ferreira, Baggio, Jussara Almeida de Oliveira“…OBJETIVO: Analisar a tendência da mortalidade por DCVB no Brasil (1996-2015) e associação com o índice de desenvolvimento humano (IDH) e o índice de vulnerabilidade social (IVS). …”
Publicado 2021
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1731por Sun, Chen, Fan, Liyuan, Wang, Wenqing, Wang, Weiwei, Liu, Lei, Duan, Wenchao, Pei, Dongling, Zhan, Yunbo, Zhao, Haibiao, Sun, Tao, Liu, Zhen, Hong, Xuanke, Wang, Xiangxiang, Guo, Yu, Li, Wencai, Cheng, Jingliang, Li, Zhicheng, Liu, Xianzhi, Zhang, Zhenyu, Yan, Jing“…BACKGROUND: Isocitrate dehydrogenase (IDH) mutation and 1p19q codeletion status have been identified as significant markers for therapy and prognosis in lower-grade glioma (LGG). …”
Publicado 2022
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1732por Yamashita, Hironori, Tourna, Aikaterini, Akita, Masayuki, Itoh, Tomoo, Chokshi, Shilpa, Ajiki, Tetsuo, Fukumoto, Takumi, Youngson, Neil A., Zen, Yoh“…Mutations in IDH1/2 and the epigenetic silencing of TET2 occur in leukaemia or glioma in a mutually exclusive manner. …”
Publicado 2021
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1733por Liu, Xiaoxue, Li, Jianrui, Xu, Qiang, Zhang, Qirui, Zhou, Xian, Pan, Hao, Wu, Nan, Lu, Guangming, Zhang, Zhiqiang“…The RP-Rs-fMRIomics models (AUROC 0.988, 0.905, 0.801) were superior to the corresponding traditional single rs-fMRI index (AUROC 0.803, 0.731, 0.632) in predicting glioma grade, IDH and survival. The RP-Rs-fMRIomics analysis, featuring high interpretability, was competitive for prediction of glioma grading, IDH genotype and prognosis. …”
Publicado 2022
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1734por Sutandyo, Noorwati, Mulyasari, Resti, Kosasih, Agus, Rinaldi, Ikhwan, Louisa, Melva, Kevinsyah, Andi Putra, Winston, Kevin“…The following keywords with their synonyms and combinations using Boolean operators were applied to all database: “myelodysplastic syndrome”, SRSF2”, “SF3B1”, “U2AF1”, “ASXL1”, “DNMT3A”, “TET2”, “IDH1”, “IDH2”, “RUNX1”, “acute myeloid leukemia progression”, and “leukemia free survival”. …”
Publicado 2022
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1735por Li, Jiabo, Wang, Xuya, Chen, Lulu, Zhang, Jinhao, Zhang, Yiming, Ren, Xiao, Sun, Jinzhang, Fan, Xiaoguang, Fan, Jikang, Li, Tao, Tong, Luqing, Yi, Li, Chen, Lei, Liu, Jie, Shang, Guanjie, Ren, Xiude, Zhang, Hao, Yu, Shengping, Ming, Haolang, Huang, Qiang, Dong, Jun, Zhang, Chen, Yang, Xuejun“…Interestingly, regardless of tumor grading, human glioma samples that were IDH1-wild-type (IDH1-WT) exhibited higher expression of TMEM158 than those with IDH1-mutant (IDH1-Mut). …”
Publicado 2022
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1736por Gonzalez, Ricardo D., Small, George W., Green, Adrian J., Akhtari, Farida S., Havener, Tammy M., Quintanilha, Julia C. F., Cipriani, Amber B., Reif, David M., McLeod, Howard L., Motsinger-Reif, Alison A., Wiltshire, Tim“…In IDH wildtype glioblastomas (GBM), MGMT status was the only significant predictor. …”
Publicado 2023
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1737por Soukup, Jiri, Gerykova, Lucie, Rachelkar, Anjali, Hornychova, Helena, Bartos, Michael Christian, Krupa, Petr, Vitovcova, Barbora, Pleskacova, Zuzana, Kasparova, Petra, Dvorakova, Katerina, Skarkova, Veronika, Petera, Jiri“…Tissue microarrays of 46 reactive glioses, 81 glioblastomas, 34 IDH1-mutant diffuse gliomas, and 23 gliomas of other types were analysed. …”
Publicado 2023
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1738por Veikutis, Vincentas, Brazdziunas, Mindaugas, Keleras, Evaldas, Basevicius, Algidas, Grib, Andrei, Skaudickas, Darijus, Lukosevicius, Saulius“…In recent years terminology has also changed. IDH-mutant, as previously known, is diagnostically used as astrocytoma and IDH-wildtype is used as glioblastoma. …”
Publicado 2023
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1739por Fernandez-Mercado, Marta, Yip, Bon Ham, Pellagatti, Andrea, Davies, Carwyn, Larrayoz, María José, Kondo, Toshinori, Pérez, Cristina, Killick, Sally, McDonald, Emma-Jane, Odero, María Dolores, Agirre, Xabier, Prósper, Felipe, Calasanz, María José, Wainscoat, James S., Boultwood, Jacqueline“…We showed that 85% of CN-AML patients have mutations in at least one of ASXL1, NPM1, FLT3, TET2, IDH1/2 and/or RUNX1. Serial samples from 19 MDS/CMML cases that progressed to AML were analyzed for ASXL1/TET2/IDH1/2 mutations; seventeen cases presented mutations of at least one of these genes. …”
Publicado 2012
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1740por Smrdel, Uros, Popovic, Mara, Zwitter, Matjaz, Bostjancic, Emanuela, Zupan, Andrej, Kovac, Viljem, Glavac, Damjan, Bokal, Drago, Jerebic, Janja“…Biopsy samples were tested for the methylation of MGMT promoter (with methylation specific polymerase chain reaction), IDH1 (with immunohistochemistry), IDH2, CDKN2A and CDKN2B (with multiplex ligation-dependent probe amplification), and 1p and 19q mutations (with fluorescent in situ hybridization). …”
Publicado 2016
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