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1781por Sloan, Caroline E., Luskin, Marlise R., Boccuti, Anne M., Sehgal, Alison R., Zhao, Jianhua, Daber, Robert D., Morrissette, Jennifer J. D., Luger, Selina M., Bagg, Adam, Gimotty, Phyllis A., Carroll, Martin“…Median OS was 2.8 years among 14 patients with intermediate cytogenetics and favorable mutational profiles (mutant NPM1 and mutant IDH1 or IDH2) and 1.3 years among patients with intermediate mutational profiles. …”
Publicado 2016
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1782por Kuipers, Johanna, Oosterhuis, Jurjen K., Paans, Wolter, Krijnen, Wim P., Gaillard, Carlo A. J. M., Westerhuis, Ralf, Franssen, Casper F. M.“…In haemodialysis (HD) patients, intradialytic hypotension (IDH) is considered one of the most frequent complications, and this is often accompanied by symptoms. …”
Publicado 2019
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1783por Yan, Xuefen, Wang, Lu, Jiang, Lingxu, Luo, Yingwan, Lin, Peipei, Yang, Wenli, Ren, Yanling, Ma, Liya, Zhou, Xinping, Mei, Chen, Ye, Li, Xu, Gaixiang, Xu, Weilai, Yang, Haiyang, Lu, Chenxi, Jin, Jie, Tong, Hongyan“…SF3B1 mutations indicated a favorable OS. IDH1 and IDH2 mutations independently indicated inferior LFS.…”
Publicado 2021
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1784por Ye, Xinxin, Yi, Qian, Shao, Jing, Zhang, Yan, Zha, Mingming, Yang, Qingwen, Xia, Wei, Ye, Zhihong, Song, Peige“…Furthermore, body mass index (BMI) and general obesity were linked to the presence of ISH, IDH and SDH. Age, waist circumference (WC) and central obesity were additionally associated with ISH, and sex, age, urban/rural setting, North/South region, WC and central obesity were additionally associated with IDH. …”
Publicado 2021
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1785por Suwala, Abigail K., Stichel, Damian, Schrimpf, Daniel, Maas, Sybren L. N., Sill, Martin, Dohmen, Hildegard, Banan, Rouzbeh, Reinhardt, Annekathrin, Sievers, Philipp, Hinz, Felix, Blattner-Johnson, Mirjam, Hartmann, Christian, Schweizer, Leonille, Boldt, Henning B., Kristensen, Bjarne Winther, Schittenhelm, Jens, Wood, Matthew D., Chotard, Guillaume, Bjergvig, Rolf, Das, Anirban, Tabori, Uri, Hasselblatt, Martin, Korshunov, Andrey, Abdullaev, Zied, Quezado, Martha, Aldape, Kenneth, Harter, Patrick N., Snuderl, Matija, Hench, Jürgen, Frank, Stephan, Acker, Till, Brandner, Sebastian, Winkler, Frank, Wesseling, Pieter, Pfister, Stefan M., Reuss, David E., Wick, Wolfgang, von Deimling, Andreas, Jones, David T. W., Sahm, Felix“…Glioblastoma IDH-wildtype presents with a wide histological spectrum. …”
Publicado 2021
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1786por Shen, Nanxi, Zhang, Shun, Cho, Junghun, Li, Shihui, Zhang, Ju, Xie, Yan, Wang, Yi, Zhu, Wenzhen“…Results were compared with DCE-MRI using receiver operating characteristic (ROC) analysis. Results: IDH1-mutated LGGs exhibited significantly lower OEF and hypoperfusion than IDH wild-type tumors (all p < 0.01). …”
Publicado 2021
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1787por Rothhammer-Hampl, Tanja, Liesenberg, Franziska, Hansen, Natalie, Hoja, Sabine, Delic, Sabit, Reifenberger, Guido, Riemenschneider, Markus J.“…Analysis of the DIRAS-1 and -2 promoter methylation status showed significantly higher methylation in IDH-mutant astrocytic and IDH-mutant and 1p/19q-codeleted oligodendroglial tumors compared to NNB. …”
Publicado 2021
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1788por Keil, Vera C., Gielen, Gerrit H., Pintea, Bogdan, Baumgarten, Peter, Datsi, Angeliki, Hittatiya, Kanishka, Simon, Matthias, Hattingen, Elke“…METHODS: 120 brain biopsies were taken in vital tumor, infiltration zone and normal brain tissue of 30 glioma patients: 17 IDH(isocitrate dehydrogenase)-wildtype glioblastoma (GBM), 1 IDH-wildtype astrocytoma °III (together prognostic group 1), 3 IDH-mutated GBM (group 2), 3 anaplastic astrocytomas IDH-mutated (group 3), 4 anaplastic oligodendrogliomas and 2 low-grade oligodendrogliomas (together prognostic group 4). …”
Publicado 2021
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1789por Kim, Hyunhee, Lim, Ka Young, Park, Jin Woo, Kang, Jeongwan, Won, Jae Kyung, Lee, Kwanghoon, Shim, Yumi, Park, Chul-Kee, Kim, Seung-Ki, Choi, Seung-Hong, Kim, Tae Min, Yun, Hongseok, Park, Sung-Hye“…Our 13 MMRD brain tumors included glioblastoma (GBM) IDH-wildtype (n = 9) including 1 gliosarcoma, astrocytoma IDH-mutant WHO grade 4 (n = 2), diffuse midline glioma (DMG) H3 K27M-mutant (n = 1), and pleomorphic xanthoastrocytoma (PXA) (n = 1). …”
Publicado 2021
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1790por Wang, Shouchao, Xiao, Feng, Sun, Wenbo, Yang, Chao, Ma, Chao, Huang, Yong, Xu, Dan, Li, Lanqing, Chen, Jun, Li, Huan, Xu, Haibo“…PURPOSE: This study aimed to develop a radiomics signature for the preoperative prognosis prediction of isocitrate dehydrogenase (IDH)-wild-type glioblastoma (GBM) patients and to provide personalized assistance in the clinical decision-making for different patients. …”
Publicado 2022
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1791por Shimizu, Kazuhide, Tamura, Kaoru, Hara, Shoko, Inaji, Motoki, Tanaka, Yoji, Kobayashi, Daisuke, Sugawara, Takashi, Wakimoto, Hiroaki, Nariai, Tadashi, Ishii, Kenji, Sakuma, Ichiro, Maehara, Taketoshi“…Results: Thirty-two patients, mostly with Glioblastoma IDH wild type (46.9%) and anaplastic astrocytoma IDH mutant (21.9%), were analyzed. …”
Publicado 2022
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1792por Li, Cong, Xi, Shaoyan, Chen, Yingshen, Guo, Chengcheng, Zhang, Ji, Yang, Qunying, Wang, Jian, Sai, Ke, Zeng, Jing, Wang, Jing, Zhang, Zhiqiang, Ke, Chao, Chen, Zhongping“…The time interval between primary and reoperation was shorter for primary high-grade glioma and/or IDH1 wild-type tumor patients than for low-grade glioma and/or IDH1 mutant tumor patients (P < 0.001). …”
Publicado 2023
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1793por Park, Yae Won, Park, Ki Sung, Park, Ji Eun, Ahn, Sung Soo, Park, Inho, Kim, Ho Sung, Chang, Jong Hee, Lee, Seung-Koo, Kim, Se Hoon“…OBJECTIVE: Cyclin-dependent kinase inhibitor (CDKN)2A/B homozygous deletion is a key molecular marker of isocitrate dehydrogenase (IDH)-mutant astrocytomas in the 2021 World Health Organization. …”
Publicado 2023
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1794por Fleischmann, Daniel Felix, Schön, Rudolph, Corradini, Stefanie, Bodensohn, Raphael, Hadi, Indrawati, Hofmaier, Jan, Forbrig, Robert, Thon, Niklas, Dorostkar, Mario, Belka, Claus, Niyazi, Maximilian“…RESULTS: 20 multifocal glioma cases (18 IDH wild-type glioblastoma cases, one diffuse astrocytic glioma, IDH wild-type case with molecular features of glioblastoma and one anaplastic astrocytoma, IDH wild-type case) were included into the analysis. …”
Publicado 2021
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1795“…This study assessed prevalence and predictors of isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH) and combined systolic and diastolic hypertension (CSDH). …”
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1796“…In gliomas, several molecular biomarkers including IDH mutation, 1p/19q co-deletion, and MGMT promotor methylation status have been introduced into neuropathological practice. …”
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1797“…Intradural or intraradicular lumbar disc herniation (IDH) is a relatively rare condition often diagnosed intraoperatively. …”
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1798por Balañá, C., Alonso, M., Hernandez, A., Perez-Segura, P., Pineda, E., Ramos, A., Sanchez, A. R., Teixidor, P., Verger, E., Benavides, M.“…We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. …”
Publicado 2017
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1799por Hicks, William H., Bird, Cylaina E., Traylor, Jeffrey I., Shi, Diana D., El Ahmadieh, Tarek Y., Richardson, Timothy E., McBrayer, Samuel K., Abdullah, Kalil G.“…Since the discovery of highly recurrent isocitrate dehydrogenase (IDH) mutations in lower-grade gliomas, there is increasing emphasis on effective modeling of IDH mutant brain tumors. …”
Publicado 2021
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1800por McCord, Matthew, Jamshidi, Pouya, Thirunavu, Vineeth, Santana-Santos, Lucas, Vormittag-Nocito, Erica, Dittman, David, Parker, Stephanie, Baczkowski, Joseph, Jennings, Lawrence, Walshon, Jordain, McCortney, Kathleen, Galbraith, Kristyn, Zhang, Hui, Lukas, Rimas V., Stupp, Roger, Dixit, Karan, Kumthekar, Priya, Heimberger, Amy B., Snuderl, Matija, Horbinski, Craig“…Optimal VAF cutoffs differed among glioma subtypes (IDH wildtype glioblastoma: 0.12–0.18, IDH mutant astrocytoma: ~0.33, IDH mutant and 1p/19q co-deleted oligodendroglioma: 0.3–0.4). …”
Publicado 2023
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