Materias dentro de su búsqueda.
Mostrando 1,861 - 1,880 Resultados de 4,168 Para Buscar '"IDH"', tiempo de consulta: 0.26s Limitar resultados
  1. 1861
    “…However, no significant relationship between the HbA1c level and IDH risk was observed (OR: 1.78, 95% CI: 0.82–3.84). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Elevated glycosylated hemoglobin levels and their interactive effects on hypertension risk in nondiabetic Chinese population: a cross-sectional survey
  2. 1862
    “…The isocitrate dehydrogenase-1 (IDH-1) mutational status and Ki-67 expression of tumors were evaluated by immunohistochemistry. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes
  3. 1863
    por Othman, Jad, Amer, Mariam, Amofa, Ruebina, Anderson, Laura, Austin, Michael J, Bashford, Alex, Belsham, Edward, Boot, Jesca, Campbell, Victoria Louise, Coats, Thomas, Collins, Angela, Crawley, Charles, Crolla, Francesca, Cross, Joe W, Dalley, Chris, Dang, Raymond, Dennis, Mike, Dhawan, Saniya, Elliott, Johnathon, Galli, Sofia, Gallipoli, Paolo, Hodgson, Katherine, Jain, Manish, Kalkur, Pallavi, Katsomitrou, Vana, Khan, Anjum, Khwaja, Asim, Krishnamurthy, Pramila, Latif, Annie, Laurie, John, Lim, Michael, Loizou, Eleana, Loke, Justin, Mannari, Deepak, Manson, Cara, Marshall, Scott R., Mobashwera, Behnaz, Murthy, Vidhya, Ochaya, Odong, Orthi, Shahzad, Palanicawandar, Renuka, Pillai, Srinivas, Radzova, Dominika, Rye, Adam, Saunders, Jamie, Smith, Matthew, Taussig, David, Taylor, Tom, Whitmill, Richard, Zhao, Rui, Freeman, Sylvie D, Craddock, Charles, Dillon, Richard
    Publicado 2021
    “…From late April 2020, venetoclax was available to patients aged >16y with NPM1 mutation without FLT3 internal tandem duplication (ITD), patients aged >50y with NPM1, IDH1 or IDH2 mutations (regardless of FLT3 status) and patients aged >60y without favourable-risk cytogenetics. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Venetoclax with Azacitidine or Low Dose Cytarabine As an Alternative to Intensive Chemotherapy in Fit Adults during the COVID19 Pandemic: Real World Data from the UK National Health Service
  4. 1864
    “…This article provides an overview and critical appraisal of the types of genetic and epigenetic aberrations that have gained significance in the molecular diagnostics of gliomas, namely deletions of chromosome arms 1p and 19q, promoter hypermethylation of the O6-methylguanine-methyl-transferase (MGMT) gene, and the mutation status of the IDH1 and IDH2 genes. In addition, the frequent oncogenic aberration of BRAF in pilocytic astrocytomas may serve as a novel diagnostic marker and therapeutic target. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Molecular diagnostics of gliomas: state of the art
  5. 1865
    “…Six loci were diagnostic (Aat-2, Gcdh-1, Gpi-A, Idh-1, Ldh-A and Mdh-A), indicating the presence of interjacent reproductive isolation. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Texto
    Biochemical comparison of two Hypostomus populations (Siluriformes, Loricariidae) from the Atlântico Stream of the upper Paraná River basin, Brazil
  6. 1866
    “…Immunohistochemically, EVNs are characterized by the robust expression of synaptophysin, but with a lack of oligodendrocyte transcription factor 2, isocitrate dehydrogenase enzyme isoform 1 (IDH1) R132/IDH2 R172 mutations and p53 immunoexpression. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Extraventricular neurocytoma in pediatric populations: A case report and review of the literature
  7. 1867
    “…We selected 19 significantly-mutated genes in AMLs, including FLT3, DNMT3A, NPM1, TET2, RUNX1, CEBPA, WT1, IDH1, IDH2, NRAS, ASXL1, SETD2, PTPN11, TP53, KIT, JAK2, KRAS, BRAF and CBL, and performed massively parallel sequencing for 114 patients with acute myeloid leukemias, mainly including those with normal karyotypes (CN-AML). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
  8. 1868
    por KOMORI, Takashi
    Publicado 2017
    “…New entities that are defined by both the histological and molecular features include glioblastoma, isocitrate dehydrogenase (IDH)-wildtype and glioblastoma, IDH-mutant; diffuse midline glioma, H3 K27M-mutant; RELA fusion-positive ependymoma; medulloblastoma, wingless (WNT)-activated and medulloblastoma, sonic hedgehog (SHH)-activated; and embryonal tumor with multilayered rosettes, C19MC-altered. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The 2016 WHO Classification of Tumours of the Central Nervous System: The Major Points of Revision
  9. 1869
    “…Currently known MPN‐associated mutations now include JAK2, MPL, LNK, CBL, CALR, TET2, ASXL1, IDH1, IDH2, IKZF1 and EZH2. Enhancing our knowledge about the mutation profile of patients may allow them to be stratified into risk groups which would aid clinical decision making. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Epigenetics in Myeloproliferative Neoplasms
  10. 1870
    “…Intramural duodenal hematoma (IDH) is a rare complication in endoscopic management of ulcer hemorrhage. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Acute duodenal intramural hematoma complicated by acute pancreatitis—a rare complication of endoscopic epinephrine injection therapy
  11. 1871
    “…Intramural duodenal hematoma (IDH) is an extremely rare complication after endoscopic biopsy. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Gastric Outlet Obstruction due to Intramural Duodenal Hematoma after Endoscopic Biopsy: Possible Therapeutic Role of Endoscopic Dilation
  12. 1872
    por Culos, Katie, Byrne, Michael
    Publicado 2019
    “…In AML, new directed agents in the relapsed/refractory setting include gilteritinib (FLT3-ITD/-TKD), ivosidenib (IDH1), and enasidenib (IDH2). In patients without targetable mutations, HMAs may be used, and early data with venetoclax-based regimens are encouraging.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Salvage Therapy after Allogeneic Hematopoietic Cell Transplantation: Targeted and Low-Intensity Treatment Options in Myelodysplastic Syndrome and Acute Myeloid Leukemia
  13. 1873
    “…Outcomes of MS using novel AML therapies, such as BCL-2 inhibitors or IDH inhibitors, remain undescribed. We describe a rare case of a 70-year-old man presenting with MS of the urinary bladder complicating known secondary AML (RUNX1 and IDH2 mutated). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Chloroma of the Bladder: A Case Report of Leukemia Progression Presenting as Hematuria
  14. 1874
    “…The most frequently involved genes are APC, ARID1A, AXIN1, BAP1, EGFR, FGFRs, IDH1/2, RAS, SMAD4, and TP53. Actionable targets include alterations of FGFRs, IDH1/2, BRAF, NTRK, and HER2. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Evolution of Treatment in Advanced Cholangiocarcinoma: Old and New towards Precision Oncology
  15. 1875
    “…The first patient treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Prolonged survival in patients with local chronic infection after high-grade glioma treatment: Two case reports
  16. 1876
    “…In this study, we focused on the effect of IDH1 wild-type glioblastoma on the human hippocampus volume. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Volumetric hippocampal changes in glioblastoma: a biomarker for neuroplasticity?
  17. 1877
    “…RESULTS: The limit of detection (LOD) for IDH1 R132H and BRAF V600E in serum was as low as 6.01 aM and 5.48 aM. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Simple and Ultrasensitive Detection of Glioma-Related ctDNAs in Mice Serum by SERS-Based Catalytic Hairpin Assembly Signal Amplification Coupled with Magnetic Aggregation
  18. 1878
    “…This trial enrolls sGBM or IDH mutant glioblastoma patients with the inclusion criteria and without the exclusion criteria. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    PTPRZ1-METFUsion GENe (ZM-FUGEN) trial: study protocol for a multicentric, randomized, open-label phase II/III trial
  19. 1879
    “…BACKGROUND: In humans, the T2‐weighted (T2W)—fluid‐attenuated inversion recovery (FLAIR) mismatch sign (T2FMM) is a specific imaging biomarker for the isocitrate dehydrogenase 1 (IDH1)‐mutated, 1p/19q non‐codeleted low‐grade astrocytomas (LGA). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The T2‐FLAIR mismatch sign as an imaging biomarker for oligodendrogliomas in dogs
  20. 1880
    “…RESULTS: Eighteen patients were enrolled (13 GBM, IDH-wild type; 2 astrocytoma, IDH-mutant, grade 3; 3 astrocytoma, IDH-mutant, grade 4). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Phase I dose-escalation study of procaspase-activating compound-1 in combination with temozolomide in patients with recurrent high-grade astrocytomas
Herramientas de búsqueda: RSS