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Mostrando 181 - 200 Resultados de 320 Para Buscar '"ITAM"', tiempo de consulta: 0.29s Limitar resultados
  1. 181
    por Roldán Xopa, José
    Publicado 2008
    Libro
    Los límites a las remuneraciones de los servidores públicos /
  2. 182
    Publicado 2011
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    Transacciones petroleras internacionales en América Latina = International oil and gas transactions in Latin America /
  3. 183
    “…This chemically regulated and SH2-delivered-inhibitory tail (CRASH-IT) switch relies on the noncovalent interaction of switch SH2 domains with phosphorylated ITAM motifs in either chimeric antigen receptors or T cell receptors. …”
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    Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains
  4. 184
    “…This activation results from the interaction of immunoglobulin (Ig)G Fc receptors containing an activation motif (ITAM) with immune complexes (ICs) and cytotoxic autoantibodies which initiates and propagates an inflammatory response. …”
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    Modulation of Immune Complex–induced Inflammation In Vivo by the Coordinate Expression of Activation and Inhibitory Fc Receptors
  5. 185
    “…In addition, tyrosine to phenylalanine substitutions in the immunoreceptor tyrosine-based activation motif (ITAM) of the FcγRIIA cytoplasmic tail abolished synergy. …”
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    Role for a Glycan Phosphoinositol Anchor in Fcγ Receptor Synergy
  6. 186
    “…Dap12 and FcRγ, the two transmembrane ITAM-containing signaling adaptors expressed in dendritic cells (DC), are implicated in the regulation of DC function. …”
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    Loss of DAP12 and FcRγ Drives Exaggerated IL-12 Production and CD8(+) T Cell Response by CCR2(+) Mo-DCs
  7. 187
    por Díaz Infante Chapa, Enrique
    Publicado 2008
    Libro
    Regulación financiera y competencia económica : la Ley para la transparencia y ordenamiento de los servicios financieros
  8. 188
    “…In contrast, FcγRIA alone, having no ITAM, was unable to internalize target particles efficiently, but did mediate pseudopod extension. …”
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    Functional Separation of Pseudopod Extension and Particle Internalization during Fcγ Receptor–mediated Phagocytosis
  9. 189
    “…Furthermore, expression of the constitutively phosphorylated LMP2A ITAM modulated rather than inhibited BCR-induced Ca(2+ )mobilization. …”
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    Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal
  10. 190
    “…MALT1 forms part of a central signaling node downstream of immunoreceptor tyrosine-based activation motif (ITAM)-containing receptors, across a broad range of immune cell subsets, and regulates NF-κB driven transcriptional responses via dual scaffolding-protease activity. …”
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    Pharmacological Inhibition of MALT1 Ameliorates Autoimmune Pathogenesis and Can Be Uncoupled From Effects on Regulatory T-Cells
  11. 191
    por Figueroa E., Raúl
    Publicado 1999
    Libro
    Entre la intervención oculta y la neutralidad estricta : España ante la guerra entre México y Estados Unidos, 1845-1848 /
  12. 192
    Publicado 1994
    Libro
    Paquete de recursos humanos
  13. 193
    “…CONCLUSIONS: Our results suggest a functional model by which PKC interacts with SHP1 to affect the phosphorylation state of CBL, the activation state of Rac and the negative regulation of ITAM signaling i.e. Fcγ receptor mediated phagocytosis. …”
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    A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis
  14. 194
    “…This also offers new information regarding the directed ability of immunoregulatory receptor-types to initiate dynamic membrane structures and provides insights into an alternative ITAM-independent target capture pathway that is functionally distinct from the classical phagocytic pathways.…”
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    Selective Regulation of Cytoskeletal Dynamics and Filopodia Formation by Teleost Leukocyte Immune-Type Receptors Differentially Contributes to Target Capture During the Phagocytic Process
  15. 195
    “…NFAT activating protein with ITAM motif 1 (NFAM1) is an ITAM bearing-transmembrane receptor that has been reported to play a role in B cell signaling and development. …”
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    NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes
  16. 196
    por de Castro, Rodrigo Orlandini
    Publicado 2011
    “…Binding of Syk to phosphorylated immunoreceptor tyrosine-based activation motifs (p-ITAM) of the receptor subunits results in conformational changes and tyrosine phosphorylation at multiple sites that leads to activation of Syk. …”
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    Regulation and Function of Syk Tyrosine Kinase in Mast Cell Signaling and Beyond
  17. 197
    “…Fine-tuning of CAR T cell activation by mutating CD3ζ chain immunoreceptor tyrosine-based activation motifs (ITAMs) in CD19-CAR T cells (containing the CD28 costimulatory domain) has proven to extend functional CAR T cell persistence in preclinical models of B cell malignancies. …”
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    Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
  18. 198
    por Lee, Wing-Yiu, Tolar, Pavel
    Publicado 2013
    “…Binding of antigen to the B cell receptor (BCR) induces conformational changes in BCR's cytoplasmic domains that are concomitant with phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs). Recently, reversible folding of the CD3ε and ξ chain ITAMs into the plasma membrane has been suggested to regulate T cell receptor signaling. …”
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    Activation of the B Cell Receptor Leads to Increased Membrane Proximity of the Igα Cytoplasmic Domain
  19. 199
    “…Here we show that cholesterol sulfate (CS), a naturally occurring analog of cholesterol, inhibits CD3 ITAM phosphorylation, a crucial first step in T cell activation. …”
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    Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol
  20. 200
    “…Data uncovered plaque-associated enrichment of microglia-related genes such as ITIM/ITAM-associated genes and pathway markers of phagocytosis. …”
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    Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology
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