Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Historia
7
Política y gobierno
6
Crítica e interpretación
5
Leyes y legislación
5
Democracia
4
Finanzas
4
Relaciones exteriores
4
Administración
3
Administración financiera
3
Contabilidad
3
Derecho
3
Filosofía del derecho
3
Poder legislativo
3
Tecnología de la información
3
Administración industrial
2
Aspectos sociales
2
Cambio exterior
2
Competitividad
2
Cooperación internacional
2
Cuerpos legislativos
2
Derecho y sociedad
2
Educación superior
2
Filosofía
2
Historia y crítica
2
Instrumentos financieros
2
Liberalismo
2
Mercadotecnia
2
México
2
Pensamiento filosófico
2
Procesamiento de datos
2
-
81por He, Xiaocui, Kläsener, Kathrin, Iype, Joseena M, Becker, Martin, Maity, Palash C, Cavallari, Marco, Nielsen, Peter J, Yang, Jianying, Reth, Michael“…Furthermore, we show that in the absence of any other BCR component, Igβ can be expressed on the B‐cell surface, where it is found in close proximity to CD19 and signals in an ITAM‐dependent manner. These data suggest that Igβ and CD19 are part of an alternative B‐cell signaling module that use continuous ITAM/PI3K signaling to promote the survival of B lymphoma and normal B cells.…”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
82por Tamanaha-Nakasone, Ayumi, Uehara, Karina, Tanabe, Yasuka, Ishikawa, Haruna, Yamakawa, Natsuko, Toyoda, Zensei, Kurima, Kiyoto, Kina, Shinichiro, Tsuneki, Masayuki, Okubo, Yuko, Yamaguchi, Sayaka, Utsumi, Daisuke, Takahashi, Kenzo, Arakawa, Hirofumi, Arasaki, Akira, Kinjo, Takao“…To evaluate our hypothesis, we compared the transformation activities of the K1 gene between AIDS-related KS and classic KS. We also analyzed ITAM activities and the downstream AKT and NF-κB. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
83por Schlesinger, Martin“…Immunoreceptor tyrosine-based activation motif (ITAM) and hemi ITAM (hemITAM) comprising receptors, especially, glycoprotein VI (GPVI), FcγRIIa, and C-type lectin-like-2 receptor (CLEC-2) are turned in the spotlight since several new mechanisms and contributions to metastasis have been attributed to this family of platelet receptors in the last years.…”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
84por Rosenlöw, Joakim, Isaksson, Linnéa, Mayzel, Maxim, Lengqvist, Johan, Orekhov, Vladislav Y.“…The cytosolic domains of these proteins are intrinsically disordered and each has an immunoreceptor tyrosine-based activation motif (ITAM). When an antigen binds to the receptor, conserved tyrosines located in the ITAMs are phosphorylated which initiate further downstream signaling. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
85
-
86
-
87
-
88por Pils, Stefan, Kopp, Kathrin, Peterson, Lisa, Delgado Tascón, Julia, Nyffenegger-Jann, Naja J., Hauck, Christof R.“…The phosphorylated ITAM-like sequence triggers GTP-loading of Rac by directly associating with the guanine nucleotide exchange factor (GEF) Vav. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
89por Busman-Sahay, Kathleen, Drake, Lisa, Sitaram, Anand, Marks, Michael, Drake, James R.“…The BCR contains five putative AP2-binding YxxØ motifs, including four that are present within two immunoreceptor tyrosine-based activation motifs (ITAMs). Using a combination of in vitro and in situ approaches, we establish that the sole mediator of AP2-dependent BCR internalization is the membrane proximal ITAM YxxØ motif in CD79b, which is a major target of mutation in ABC DLBCL. …”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
90“…The inhibitory effect of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters DAP12 and FcεRI γ-chain (FcRγ) has been found in many immune functions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
91por Dangelmaier, Carol, Vari, Hymavathi Reddy, Wright, Monica, Kostyak, John C., Kunapuli, Satya P.“…OBJECTIVES: One proposed hypothesis for signaling cascade is that Syk bridges two receptors through phosphorylated hemITAM motifs. We demonstrated that the phosphorylated hemITAM stimulates PI3 kinase/Btk pathways to activate Syk. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
92por Gangopadhyay, Kaustav, Roy, Arnab, Chandradasan, Athira C., Roy, Swarnendu, Debnath, Olivia, SenGupta, Soumee, Chowdhury, Subhankar, Das, Dipjyoti, Das, Rahul“…The regulatory module of ZAP-70 comprises of a tandem SH2 domain that binds to its ligand, doubly-phosphorylated ITAM peptide (ITAM-Y2P), in two kinetic steps: a fast step and a slow step. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
93
-
94
-
95“…TULA-2 negatively regulates platelet signaling mediated by ITAM- and hemITAM-containing membrane receptors that are dependent on the protein tyrosine kinase Syk, which currently represents the best-known dephosphorylation target of TULA-2. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
96
-
97
-
98
-
99
-
100