Mostrando 161 - 180 Resultados de 320 Para Buscar '"ITAM"', tiempo de consulta: 0.14s Limitar resultados
  1. 161
    Publicado 2000
    Libro
  2. 162
    por Raigosa Sotelo, Luis
    Publicado 2008
    Libro
  3. 163
  4. 164
    Publicado 1984
    Revista
  5. 165
    “…The Src42A-Draper-Shark-mediated signaling axis is homologous to the well-established SFK-ITAM-Syk-signaling pathway used in vertebrate adaptive immune responses. …”
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  6. 166
    por Carstens, Catherine Mansell
    Publicado 1992
    Libro
  7. 167
    Publicado 2004
    Libro
  8. 168
    por Vivó, Buenaventura, 1820-1872
    Publicado 2017
    Libro
  9. 169
    “…This defect was observed following activation of both immunoreceptor tyrosine-based activation motif (ITAM) signaling by collagen-related peptide (CRP) and G protein–coupled receptor (GPCR) signaling by thrombin and the thromboxane mimetic U46619. …”
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  10. 170
    “…However, mutagenesis of the immunoreceptor tyrosine-based activation motifs (ITAMs), present three times in TCR-ζ and once in CD3ε, revealed that the induction of cytoskeletal rearrangements required the presence of at least one intact ITAM. …”
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  11. 171
    “…In KARAP/DAP12 mutant mice bearing a nonfunctional ITAM, we found a considerable increase in viral titers in the spleen (30–40-fold) and in the liver (2–5-fold). …”
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  12. 172
    “…In this study we show that two platelet glycoprotein receptors that signal via an immunoreceptor tyrosine-based activation motif (ITAM) or an ITAM-like domain, namely the collagen receptor complex glycoprotein VI (GPVI)-FcR γ-chain and the C-type lectin-like receptor 2 (CLEC-2), respectively, support constitutive (i.e. agonist-independent) signaling in a cell line model using a nuclear factor of activated T-cells (NFAT) transcriptional reporter assay that can detect low level activation of phospholipase Cγ (PLCγ). …”
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  13. 173
    “…BACKGROUND: FcRγ is an immunoreceptor tyrosine-based activation motif (ITAM)-signalling protein essential for immunoreceptor signaling and monocyte, macrophage and NK cell function. …”
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  14. 174
    “…Together, our results demonstrate that Grb2 family adaptors are critical regulators of ITAM and ITT signaling in naïve and IgE-switched human B cells.…”
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  15. 175
  16. 176
    “…We previously reported that GPNMB contributes to the initiation and malignant progression of breast cancer through the hemi‐immunoreceptor tyrosine‐based activation motif (hemITAM) in its ICD. Furthermore, we showed that the tyrosine residue in hemITAM is involved in induction of the stem‐like properties of breast cancer cells. …”
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  17. 177
    “…The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526 (kinase domain). …”
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  18. 178
    Electrónico Software eBook
  19. 179
    por Perales Contreras, Jaime
    Publicado 2013
    Libro
  20. 180
    por Roldán Xopa, José
    Publicado 2008
    Libro
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