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  1. 2881
    “…Morquio A syndrome (mucopolysaccharidosis IVA) is a lysosomal storage disorder associated with skeletal and joint abnormalities and significant non-skeletal manifestations including respiratory disease, spinal cord compression, cardiac disease, impaired vision, hearing loss, and dental problems. …”
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    International Guidelines for the Management and Treatment of Morquio A Syndrome
  2. 2882
    “…The glutamate release-inhibiting effect of PEA was prevented by the Cav2.1 (P/Q-type) channel blocker ω-agatoxin IVA or the protein kinase A inhibitor H89, not affected by the intracellular Ca(2+) release inhibitors dantrolene and CGP37157, and partially antagonized by the cannabinoid CB1 receptor antagonist AM281. …”
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    Palmitoylethanolamide Inhibits Glutamate Release in Rat Cerebrocortical Nerve Terminals
  3. 2883
    “…Advanced lymphedema is characterized by irreversible skin fibrosis (stage IIIb) and nonpitting edema, with leather-like skin, skin crypts, and ulcers with or without involvement of the toes (stage IVa and IVb, respectively). Recently, surgical treatment of advanced lymphedema has been a challenging reconstructive modality. …”
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    Vascularized Free Lymph Node Flap Transfer in Advanced Lymphedema Patient after Axillary Lymph Node Dissection
  4. 2884
    por Ahi, Yadvinder S., Mittal, Suresh K.
    Publicado 2016
    “…Characterization of empty capsids assembled in the absence of one or more components involved in packaging, identification of the unique vertex, and demonstration of the role of IVa2, the putative packaging ATPase, in genome packaging have provided compelling evidence that AdVs follow a sequential assembly pathway. …”
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    Components of Adenovirus Genome Packaging
  5. 2885
    “…Here we describe the determination of the crystal structures of three type IVa pilins proteins from the thermophile Thermus thermophilus. …”
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    Structures of type IV pilins from Thermus thermophilus demonstrate similarities with type II secretion system pseudopilins
  6. 2886
    “…Extensive experiments are carried out on public dataset from “BCI Competition III Dataset IVa” and “BCI Competition IV Database 2a.” The results show that our proposed three methods yield higher accuracies compared with prevailing approaches such as CSP and CSSP.…”
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    Low-Rank Linear Dynamical Systems for Motor Imagery EEG
  7. 2887
    “…Repeated histological analysis established a diagnosis of folliculotropic mycosis fungoides stage IVA2, and the malignant clone was confirmed to be of donor origin. …”
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    Donor-derived mycosis fungoides following reduced intensity haematopoietic stem cell transplantation from a matched unrelated donor
  8. 2888
    “…Pollen from false ragweed (Iva xanthiifolia) was used as an allergy-causing model deposited as aerosol using the Vitrocell(®) Powder Chamber (VPC) on Transwell(®) inserts, while being coated with either Bepanthen(®) Eye and Nose Ointment and petrolatum. …”
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    Combining MucilAir™ and Vitrocell(®) Powder Chamber for the In Vitro Evaluation of Nasal Ointments in the Context of Aerosolized Pollen
  9. 2889
    “…The unusual amino acid residues of peptaibols, i.e., α-aminoisobutyric acid (Aib), isovaline (Iva), and the C-terminal 1,2-amino alcohol make them unique among peptides. …”
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    New 19-Residue Peptaibols from Trichoderma Clade Viride
  10. 2890
    “…We have evaluated in vitro and in vivo the affinity of an AAV2 vector to bone matrix, hydroxyapatite (HA) to treat Mucopolysacccharidosis IVA. METHODS: To increase vector affinity to HA, an aspartic acid octapeptide (D8) was inserted immediately after the N-terminal region of VP2 capsid protein. …”
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    Tailoring the AAV2 capsid vector for bone-targeting
  11. 2891
    “…One such mobile genomic element, p45 carries ~45 kbp of genes, including the Lvh (Legionella Vir homolog) type IVa secretion system. This element was evaluated for its contribution to L. pneumophila environmental resilience and virulence-related characteristics by comparing clinically isolated strain Philadelphia-1 that carries p45, Lp01 that lacks p45, and Lp01 with p45 reintroduced, Lp01(+p45). …”
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    Legionella pneumophila p45 element influences host cell entry and sensitivity to sodium
  12. 2892
    “…Zingibroside R1, chikusetsusaponin IVa, and calenduloside E, three metabolites of Ro, were detected in the plasma of Ro-treated tumour-bearing mice and showed excellent anti-tumour effects as well as anti-angiogenic activity. …”
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    Inhibitory Effects of Ginsenoside Ro on the Growth of B16F10 Melanoma via Its Metabolites
  13. 2893
    “…Furthermore, in-frame deletion of the SPM domain from the ApxIVA protein of Actinobacillus pleuropneumoniae attenuated the virulence of this porcine pathogen in a pig respiratory challenge model. …”
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    Structural Basis of Ca(2+)-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins
  14. 2894
    “…The lung tumor was biopsied under bronchoscopic and CT guidance, and based on the pathological results, we diagnosed pineal metastasis of pulmonary sarcomatoid carcinoma (cT3N1M1b Stage IVA). Stereotactic radiotherapy for the metastatic pineal tumor and systemic chemotherapy (carboplatin + pemetrexed) were pursued, but hemorrhage of the tumor occurred, hydrocephalus worsened, and neoplastic meningitis was diagnosed by MRI. …”
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    Diplopia Presenting in a Case of Pineal Metastasis of Pulmonary Sarcomatoid Carcinoma Refractory to Treatment
  15. 2895
    “…CASE DESCRIPTION: A heavily pretreated 57-year-old SS woman (stage IVA) was randomized in the mogamulizumab arm of MAVORIC at our Institution. …”
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    Impressive Continuous Complete Response after Mogamulizumab in a Heavily Pretreated Sézary Syndrome Patient
  16. 2896
    “…The vast majority (92%) of the patients were at stage III-IVa and had well (55%) to moderate (31%) differentiated tumor. …”
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    Elective Submandibular Gland Resection in Patients with Squamous Cell Carcinomas of the Tongue
  17. 2897
    “…The drug is a combination of three individual drugs which are elexacaftor (ELX), tezacaftor (TEZ), and ivacaftor (IVA). This trio increases the activity of the cystic fibrosis transmembrane conductance regulator (CFTR) protein and reduces the mortality and morbidity rates in CF patients. …”
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    A Review of Trikafta: Triple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy
  18. 2898
    “…Eight percent of temporomandibular joints were classified as class IVA. There were no statistically significant differences in the prevalence of temporomandibular disorder with respect to gender (p = 0.838639). …”
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    The Prevalence and Overlaps of Temporomandibular Disorders in Patients with Myofascial Pain with Referral—A Pilot Study
  19. 2899
    “…The whole-genome sequence of this strain showed the presence of putative β-lactamase, aac(3)-IVa, and multidrug efflux pump-encoding genes, which could explain the observed multidrug resistance phenotype. …”
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    MCR-5-Producing Colistin-Resistant Cupriavidus gilardii Strain from Well Water in Batna, Algeria
  20. 2900
    “…He accepted the targeted therapy because the lung tumor epidermal growth factor receptor mutation (exon19 deletion) was positive, and preoperative staging of lung adenocarcinoma was stage IVA. After an 8‐month follow‐up, he is still alive and well, with no local recurrence or distant metastases. …”
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    Ureteral metastasis from pulmonary adenocarcinoma: A case report and literature review
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