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3121por Kombathula, Sri Harsha, Jagadesan, Pandjatcharam, Sinnatamby, Mourougan, Menon, Abhilash, Kannikanti, Durga Harika, R, Chandramouli, Mathew, John M“…Materials and methods Patients of carcinoma cervix belonging to FIGO (The International Federation of Gynecology and Obstetrics) stages IB2- IVA were recruited into the study. The patients were treated with VMAT to an EBRT (External Beam Radiation Therapy) dose of 50.4Gy in 28 fractions, which was followed by a brachytherapy schedule of 8Gy for each fraction to point A for three fractions. …”
Publicado 2023
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3122por Wang, Wei Cen, Preti, Beatrice, Read, Nancy, Gibson, Paul, Kwan, Keith, Winquist, Eric“…CASE REPORT: A male patient presented at age 15 with stage IVA EBV-related NPC. Despite response to initial chemoradiation and adjuvant chemotherapy, the patient experienced metastatic cancer relapse in lymph nodes and bone. …”
Publicado 2023
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3123“…RESULTS: The classification accuracy of the proposed method achieved 87.88 %, 90.07 %, and 76.06 % on public dataset IV part I, III part IVa and the self-collected dataset, respectively. …”
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3124por Xu, Zhuofei, Zhou, Yan, Li, Liangjun, Zhou, Rui, Xiao, Shaobo, Wan, Yun, Zhang, Sihua, Wang, Kai, Li, Wei, Li, Lu, Jin, Hui, Kang, Mingsong, Dalai, Baolige, Li, Tingting, Liu, Lei, Cheng, Yangyi, Zhang, Lei, Xu, Tao, Zheng, Huajun, Pu, Shiying, Wang, Bofei, Gu, Wenyi, Zhang, Xiang-Lin, Zhu, Geng-Feng, Wang, Shengyue, Zhao, Guo-Ping, Chen, Huanchun“…In addition to confirming the lack of ApxI toxin, identification of a nonsense mutation in apxIVA and a 5′-proximal truncation of the flp operon deleting both its promoter and the flp1flp2tadV genes have provided convincing scenarios for the low virulence property of JL03. …”
Publicado 2008
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3125“…In further experiments we found that the CB(1)R-independent effect of 10 μM WIN 55,212-2 at glutamatergic synapses was fully abolished, when slices were pre-treated with ω-conotoxin GVIA, but not with ω-agatoxin IVA. These data suggest that, in the hippocampus, WIN 55,212-2 reduces glutamate release from Schaffer collaterals solely via CB(1)Rs in the nM concentration range, whereas in μM concentrations, WIN 55,212-2 suppresses excitatory transmission, in addition to activation of CB(1)Rs, by directly blocking N-type voltage-gated Ca(2+) channels independent of CB(1)Rs.…”
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3126Publicado 1996“…The P-type Ca channel blocker, omega-agatoxin IVA (200 nM), had variable and insignificant effects. …”
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3127por Choi, Gi-Hong, Ju, Man-Ki, Kim, June-Young, Kang, Chang-Moo, Kim, Kyung-Sik, Choi, Jin-Sub, Han, Kwang-Hyub, Park, Mi-Suk, Park, Young-Nyun, Lee, Woo-Jung, Kim, Byong-Ro“…The dynamic computer tomography (CT) performed due to elevated serum alpha-fetoprotein (128 ng/mL) demonstrated two hepatic nodules, which were located near the liver capsule. A nodule in Segment IVa had a slight enhancement during both the arterial and portal phases, and another nodule in Segment VI showed a slight enhancement only in the portal phases. …”
Publicado 2008
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3128por Lone, Abdul G., Deslandes, Vincent, Nash, John H. E., Jacques, Mario, MacInnes, Janet I.“…Transcription of a number of known virulence genes including apxIVA and the gene for SapF, a protein which is involved in resistance to antimicrobial peptides, was also up-regulated in BALF. …”
Publicado 2009
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3129por Watakabe, Akiya, Komatsu, Yusuke, Sadakane, Osamu, Shimegi, Satoshi, Takahata, Toru, Higo, Noriyuki, Tochitani, Shiro, Hashikawa, Tsutomu, Naito, Tomoyuki, Osaki, Hironobu, Sakamoto, Hiroshi, Okamoto, Masahiro, Ishikawa, Ayako, Hara, Shin-ichiro, Akasaki, Takafumi, Sato, Hiromichi, Yamamori, Tetsuo“…In situ hybridization analyses revealed that both mRNA species were highly concentrated in the geniculorecipient layers IVA and IVC, where they were coexpressed in the same neurons. …”
Publicado 2009
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3130“…To evaluate the toxicities and efficacies of two fractionation regimens of high-dose-rate brachytherapy in uterine cervical cancer, patients were stratified by stage Ib-IIa versus IIb-IVa, and randomly assigned to receive 3 Gy fractions (group A) or 5 Gy fractions (group B). …”
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3131por Geara, Fady B, Shamseddine, Ali, Khalil, Ali, Abboud, Mirna, Charafeddine, Maya, Seoud, Muhieddine“…MATERIALS/METHODS: Between May 2000 and May 2004, 31 women with FIGO stage IB2-IVA cervical cancer or with postsurgical pelvic recurrence were enrolled into this phase II study and randomized to receive on a weekly basis either 40 mg/m(2 )Cisplatin (group I; 16 patients) or 50 mg/m(2 )paclitaxel (group II; 15 patients) concurrently with radiotherapy. …”
Publicado 2010
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3132por Yoshida, Kenji, Sasaki, Ryohei, Nishimura, Hideki, Miyawaki, Daisuke, Kawabe, Tetsuya, Okamoto, Yoshiaki, Nakabayashi, Koji, Yoshida, Shigeki, Sugimura, Kazuro“…Of these 40 patients, 25 were classified as FIGO stage I or II and 15 as stage III or IVA. Thirty-five patients were treated with radical RT (RRT), and five were treated with surgery plus adjuvant RT (S + ART). …”
Publicado 2010
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3133“…Consistent with our hypothesis, AD frontal cortex showed significant increases in protein and mRNA levels of cPLA(2)-IVA, secretory sPLA(2)-IIA, cyclooxygenase-1 and -2, membrane prostaglandin (PG) synthase-1 and lipoxygenase-12 and -15. …”
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3134“…Adenovirus replication was inhibited by siRNAs directed against the adenoviral E1A, DNA polymerase, preterminal protein (pTP), IVa2, hexon, and protease genes. Silencing of early and middle genes was more effective in inhibiting adenovirus multiplication than was silencing of late genes. …”
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3135por Kellom, Matthew, Basselin, Mireille, Keleshian, Vasken L, Chen, Mei, Rapoport, Stanley I, Rao, Jagadeesh S“…High-dose LPS infusion upregulated brain protein and mRNA levels of AA cascade markers (cytosolic cPLA(2)-IVA, secretory sPLA(2)-V, cyclooxygenase-2 and 5-lipoxygenase), and of transcription factor NF-κB p50 DNA binding activity. …”
Publicado 2012
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3136por Matsuura, Kanji, Okabe, Tomoyuki, Fujita, Kazushi, Tanimoto, Hirotoshi, Akagi, Yukio, Kagemoto, Masayuki“…There were three stage IIB, six stage IIIB and seven patients with stage IVA disease. A total of 10 patients were treated with a median dose of 66 Gy with a median overall treatment time (OTT) of 40 days delivered by a concomitant boost (CCB), and a median dose of 60 Gy with a median OTT of 47 days was administered for six patients by conventional fractionation (CF). …”
Publicado 2012
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3137por Ahmad, Moaz, Ansari, Abulaish, Tarique, Mohammed, Satsangi, Akash Tripathi, Tuteja, Renu“…The N-terminal fragment (PfUDN) containing UvrD helicase domain, which consists of helicase motifs Q, Ia–Id, II, III and most of motif IV, and the C-terminal fragment (PfUDC1) containing UvrD helicase C terminal domain, consisting of remaining part of motif IV and motifs IVa–IVc and 161 amino acids of intervening sequence between motif IV and V, possess ssDNA-dependent ATPase and DNA helicase activities in vitro. …”
Publicado 2012
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3138por Taha, Ameer Y, Gao, Fei, Ramadan, Epolia, Cheon, Yewon, Rapoport, Stanley I, Kim, Hyung-Wook“…Brains were assayed for markers of AA metabolism (calcium-dependent cytosolic cPLA(2) IVA and cyclooxygenases), DHA metabolism (calcium-independent iPLA(2) VIA and lipoxygenases), brain-derived neurotrophic factor (BDNF), and synaptic integrity (drebrin and synaptophysin). …”
Publicado 2012
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3139por Opfermann, Krisha J, Wahlquist, Amy, Watkins, John, Kohler, Matthew, Jenrette, Joseph“…RESULTS: The records of 50 patients with FIGO stage IB1-IVA cervical cancer undergoing LDR brachytherapy at our institution were identified. …”
Publicado 2012
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3140por Williams, Paul T., Zhao, Xue-Qiao, Marcovina, Santica M., Brown, B. Greg, Krauss, Ronald M.“…RESULTS: The change in the percent stenosis of the most severe proximal lesions increased in association with higher concentrations of the small LDL subfractions LDL-IIIb (24.2–24.6 nm) and LDL-IVa (23.3–24.1 nm) before (both P = 0.002) and after (P = 0.01 and P = 0.03 respectively) adjustment for treatment group and on-study HDL-cholesterol, LDL-cholesterol, and triglyceride concentrations. …”
Publicado 2013
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