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  1. 3841
    “…Two BrGRP genes-w546 (Bra030284) and w1409 (Bra014000), both belonging to the subfamily Subclass IVa RBP-GRP (RNA binding protein-glycine rich protein), were up-regulated under 150 mmol⋅L(–1) NaCl stress in Chinese cabbage. …”
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    Molecular Characterization, Expression Pattern and Function Analysis of Glycine-Rich Protein Genes Under Stresses in Chinese Cabbage (Brassica rapa L. ssp. pekinensis)
  2. 3842
    “…The analysis of 150 patients undergoing curative surgery revealed 70 stage I TET (46.66%), 49 stage II (32.66%), 19 stage III (12.66%), 6 stage IVa (4%) and 6 stage IVb (4%) at the first hospital admission. …”
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    Stage-related outcome for thymic epithelial tumours
  3. 3843
    por Nieuwenhuizen, Sanne, Puijk, Robbert S., van den Bemd, Bente, Aldrighetti, Luca, Arntz, Mark, van den Boezem, Peter B., Bruynzeel, Anna M. E., Burgmans, Mark C., de Cobelli, Francesco, Coolsen, Marielle M. E., Dejong, Cornelis H. C., Derks, Sarah, Diederik, Arjen, van Duijvendijk, Peter, Eker, Hasan H., Engelsman, Anton F., Erdmann, Joris I., Fütterer, Jurgen J., Geboers, Bart, Groot, Gerie, Haasbeek, Cornelis J. A., Janssen, Jan-Jaap, de Jong, Koert P., Kater, G. Matthijs, Kazemier, Geert, Kruimer, Johan W. H., Leclercq, Wouter K. G., van der Leij, Christiaan, Manusama, Eric R., Meier, Mark A. J., van der Meijs, Bram B., Melenhorst, Marleen C. A. M., Nielsen, Karin, Nijkamp, Maarten W., Potters, Fons H., Prevoo, Warner, Rietema, Floris J., Ruarus, Alette H., Ruiter, Simeon J. S., Schouten, Evelien A. C., Serafino, Gian Piero, Sietses, Colin, Swijnenburg, Rutger-Jan, Timmer, Florentine E. F., Versteeg, Kathelijn S., Vink, Ted, de Vries, Jan J. J., de Wilt, Johannes H. W., Zonderhuis, Barbara M., Scheffer, Hester J., van den Tol, Petrousjka M. P., Meijerink, Martijn R.
    Publicado 2020
    “…When easily resectable and/or ablatable (stage IVa), (neo)adjuvant systemic therapy is not indicated. …”
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    Resectability and Ablatability Criteria for the Treatment of Liver Only Colorectal Metastases: Multidisciplinary Consensus Document from the COLLISION Trial Group
  4. 3844
    “…The majority of patients had 67% thymoma (67%, n = 16) and AJCC8 III–IVA disease (58%, n = 14). Median age was 58.5 years (range: 33–76), median initial tumor volume was 187.1 cc (range: 28.7–653.6) and diameter was 8.5 cm (range: 4.5–14.3). …”
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    Radiologic response of chemotherapy alone versus radiation and chemotherapy in the treatment of locally‐advanced or advanced thymic epithelial tumors
  5. 3845
    “…ST152 and ST121 were found only in specific sample categories within defined locations, while ST8 and ST772 were distributed across most sample categories and locations. Three SCCmec types, IVa, V and Vc, were identified. All MRSA isolates possessed virulence genes including aur, clpP, coa, fnbA, esaA, hly, hla, ica, isdA, srtB, sspA, and vWbp, among others. …”
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    Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities
  6. 3846
    “…Pilot newborn screening programs for MPS I, II, VI, IVA, and IIIB were progressively introduced in Taiwan from 2016, and 48% (16/33) of MPS patients diagnosed between 2016 and 2019 were diagnosed by one of these screening programs, with a median diagnostic age at 0.2 years. …”
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    Survival and diagnostic age of 175 Taiwanese patients with mucopolysaccharidoses (1985–2019)
  7. 3847
    “…METHODS: Five patients with LACC (FIGO stages IIb–IVa) treated with radiochemotherapy and IGABT were included. …”
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    Hybrid TRUS/CT with optical tracking for target delineation in image-guided adaptive brachytherapy for cervical cancer
  8. 3848
    “…Results: Altogether, 2670 DEGs were obtained by differential analysis, and 371 drug targets were predicted for four active components (Araloside A, Chikusetsusaponin IVa, Ginsenoside Rg2, and Ginsenoside Ro). A total of 52 overlapping genes were included in the PPI network and the KEGG analysis. …”
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    Computational Prediction of Antiangiogenesis Synergistic Mechanisms of Total Saponins of Panax japonicus Against Rheumatoid Arthritis
  9. 3849
    “…CONCLUSION: We experienced a case of Stage IVa colorectal LCNEC accompanied by disseminated peritoneal leiomyomatosis. …”
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    A case of colorectal large cell neuroendocrine carcinoma accompanied by disseminated peritoneal leiomyomatosis
  10. 3850
    “…In case 1, a 62-year-old man was diagnosed with stage IVA adenocarcinoma. Nivolumab monotherapy was prescribed as second-line therapy and later discontinued due to financial reasons. …”
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    Late-onset programmed cell death protein-1 inhibitor-induced pneumonitis after cessation of nivolumab or pembrolizumab in patients with advanced non-small cell lung cancer: a case series
  11. 3851
    “…VF assessment was performed using the lateral spine imaging IVA™ mode with a Hologic Horizon® densitometer using semi-quantitative approach. …”
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    Vertebral Fractures Occur Regardless of Acromegaly Activity and Are Best Predicted by Proximal Femur Cortical Volumetric Bone Mineral Density
  12. 3852
    “…MATERIALS AND METHODS: Patients with cervical cancer stage I–IVA underwent radiotherapy alone or chemoradiotherapy using 3DCRT (n = 75) or VMAT (n = 30). …”
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    Conventional 3D conformal radiotherapy and volumetric modulated arc therapy for cervical cancer: Comparison of clinical results with special consideration of the influence of patient- and treatment-related parameters
  13. 3853
    “…The median (interquartile range) follow-up was 3.62 (1.63-5.47) years, and most patients were men (1052 [89.1%] men) with a primary tumor in the tonsils (712 patients [60.3%]), moderately differentiated histology (604 patients [51.2%]), clinical N2 disease (858 patients [72.7%]), and clinical stage IVA disease (938 patients [79.5%]). The mean (SD) age was 54.59 (10.35) years. …”
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    Association of Primary Treatment Modality for Advanced-Stage Oropharyngeal Squamous Cell Carcinoma With Survival Outcomes
  14. 3854
    “…Modified staging was used (mAJCC v.7): group A: stages I‐III (excluding T2bN0); group B: stage IVa (excluding T2bN1M0); group C: liver metastases (T2bN0/1); and group D: stage IVb (extrahepatic metastases). …”
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    Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System
  15. 3855
    “…RESULTS: A total of 547 patients with stage II–IVA ESCC treated with dCRT from the retrospective study were included. …”
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    Predicting Severe Radiation Esophagitis in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma Receiving Definitive Chemoradiotherapy: Construction and Validation of a Model Based in the Clinical and Dosimetric Parameters as Well as Inflammatory Indexes
  16. 3856
    “…Patient and methods: Data of 666 retrospective- and 143 prospective-stage III-IVA/B HNSCC patients were collected. A multivariable Cox proportional-hazards model was trained to predict overall survival (OS) using diagnostic CT-based radiomics features extracted from the primary tumour. …”
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    A Prospectively Validated Prognostic Model for Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Based on Radiomics of Computed Tomography Images
  17. 3857
    “…METHODS: This retrospective study included 106 patients with cervical cancer (FIGO stage IB1–IVa) between October 2017 and May 2019. Patients were randomly divided into a training cohort (n = 74) and validation cohort (n = 32). …”
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    Radiomic Score as a Potential Imaging Biomarker for Predicting Survival in Patients With Cervical Cancer
  18. 3858
    “…METHODS: We retrospectively analysed the clinical data of ESCC patients with clinical stage II–IVa who underwent CCRT. Then, we compared patients who received CCRT and AC (CCRT + AC group) with those who received CCRT alone (CCRT group). …”
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    Short-term response might influence the treatment-related benefit of adjuvant chemotherapy after concurrent chemoradiotherapy for esophageal squamous cell carcinoma patients
  19. 3859
    “…PURPOSE: We aimed to determine the cost-effectiveness of diagnostic tests, ie, computed tomography (CT), magnetic resonance imaging (MRI), and fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (PET⁄CT) for para-aortic lymph node detection (PALND), in locally advanced cervical cancer (LACC) patients (stages IB3–IVA) with or without laparoscopic lymphadenectomy (LL) compared with no investigation (NoIx) based on provider and societal perspectives during 5 years. …”
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    Cost-Effectiveness Analysis of Diagnostic Tests for Para-Aortic Lymph Node Detection in Locally Advanced Cervical Cancer
  20. 3860
    “…According to the eighth version ofAmerican Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC) staging, we selected patients with a Pathological Tumor Node Metastasis (pTNM) stage ranging from IA to IVA for analysis. RESULTS: Among the 816 qualified patients, 577 did not have coeliac trunk lymph node metastasis based on preoperative abdominal enhanced CT, and common hepatic arterial lymph node dissection was performed during the operation (observation group). …”
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    Significance of the dissection of common hepatic arterial lymph nodes in patients with oesophageal carcinoma: a multicentre retrospective study
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