“…ECS prior to intracranial MT for TO (n = 222) was compared to MT as standard of care (control group; acute intracranial vessel occlusion without concomitant ipsilateral ICA-occlusion or high-grade stenosis [C; n = 849]). …”
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“…Compared with ST2, ST130, ST20 and ST59 clones, ST466 clone had the highest resistance rate to tetracycline (50.00%), the second highest prevalence of ACME-arcA (65.00%), bhp (30.00%) and qacA/B (65.00%), very low prevalence of carriage of icaA (0.00%) and biofilm formation (0.00%), the lack of sesI and high prevalence of aap, altE and aae (> 90%), which was similar to the characteristics of ST59 clone with one locus difference from ST466. …”
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“…Further testing revealed an elevated GAD-65 antibody of >250 IU/mL (<5) but normal ICA 512 and insulin autoantibody. His clinical picture was consistent with IPEX syndrome, confirmed with rapid whole genome sequencing showed a pathogenic hemizygous c.1010G>A p.Arg337Gln variant in the FOXP3 gene. …”
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“…Most common occlusions were tandem lesions (ICA + MCA = 64.9%) and BA + bilateral VA (18.9%). …”
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“…Finally, all subjects were screened for presence and abundance of autoantibodies targeting islet cell cytoplasmic proteins (ICA), glutamate decarboxylase 2 (GAD65), zinc transporter 8 (ZNT8), insulinoma antigen 2 (IA-2), tissue transglutaminase, and thyroid peroxidase, while β cell function was gauged by measuring c-peptide levels. …”
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“…We used group-independent component analysis (group-ICA) and extracted 53 maximally independent components (ICs) for the whole brain. …”
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“…Biofilms grown in our flow chamber in the plasma media were also demonstrated to involve an upregulation of the biofilm-forming-related genes icaA, fnbA, and alt. The BLI and SEM results from K-wire experiments revealed that the in vitro growth and biofilm formation by UAMS-1 and USA300 on stainless-steel and titanium surfaces were virtually identical. …”
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“…The collateral circulation collateral circulation pathway included 14 cases with anterior communicating artery(ACoA), 7 cases with posterior cerebral artery (PCA)-middle cerebral artery (MCA) leptomeningeal anastomosis (LMA), 5 cases with ophthalmic artery(OA), 3 cases with lateral posterior communicating artery(PCoA), 1 case with internal carotid artery (ICA) stealing, 1 case with new Moyamoya vessels, and 4 cases of other types. …”
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“…And in nano-scale, a drug cargo icariin@Mg-MOF-74 (ICA@MOF) was wrapped in ECM-like structure that can control release of icariin and Mg(2+). …”
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“…The most prevalent toxin-encoding genes detected were hla, hld, icaA, and clfA (96.1–100%). Forty-three (100%, 43/43) isolates harbored more than 18 of the tested virulence genes in adults and eight virulence genes (23.5%, 8/34) in children. …”
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“…For patients with available thin-slice (≤ 2.5 mm) imaging, we performed similar analyses for general and quantitative characteristics (HAS, occlusion location, CBS, [relative] thrombus density, thrombus length, perviousness, distance from ICA-terminus). RESULTS: In 332 included patients, the presence of HAS (aβ 7.8 [95% CI 3.9–11.7]) and shift towards a more proximal occlusion location (aβ 3.9 [95% CI 0.6–7.1]) were independently associated with increased RBC and decreased fibrin/platelet content. …”
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“…DInSAR data was analysed by applying Independent Component Analysis (ICA) to decompose the time-varying ground deformation pattern of both volcanoes. …”
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“…Genes associated with ABR (tetK, tetM, aac6’, norA, norB, lmrS, blaR, blaZ, etc.), toxin production (hla, hlab, lukD, etc.), adherence (fmbA, fnbB, clfA, clfB, icaABCD, etc.), and host immune invasion (spa, sbi, cap, adsA, etc.) were identified by analyzing whole-genome sequences. …”
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“…She underwent a left upper arm arterial duplex which showed 50-99% left subclavian and left axillary artery stenosis along with bilateral ICA stenosis. Lipid profile showed Total-C 112 mg/dL, LDL-C 59 mg/dL and HDL-C 34 mg/dL. …”
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“…Autoantibody testing was negative for glutamic acid decarboxylase (GAD), islet cell antibody (ICA), and zinc transporter 8 (ZnT8). The fasting C-peptide level was detectable at 1.87 ng/mL. …”
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“…The CT attenuation values of the arteries were higher in Group A than in B [internal carotid artery (ICA) =548±112 vs. 454±85 Hounsfield units (HU), middle cerebral artery (MCA) =453±118 vs. 388±70 HU, and basilar artery (BA) =431±99 vs. 360±83 HU] (P<0.01). …”
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“…METHOD: Patients with severe stenosis or occlusion of ICA or MCA M1, who underwent MRI within 72 h from stroke onset were reviewed. …”
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“…The decreased protein expression of PI3K (p55), AKT, eNOS, phospho-Enos (Ser1177), cyclic guanosine monophosphate (cGMP) and increased level of phospho-eNOS (Thr495), phosphodiesterase type 5 (PDE5), L-type calcium channel (ICa-L) in CC of WTDM were improved in that of TGDM, but deteriorated again with HOE140 in TGDMH. …”
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“…Additional work-up revealed fasting C-peptide level of 2.09 (1.1−4.4 ng/mL), GAD-65 Ab titers: <5.0 U/mL (0.0−5.0 units/mL), and negative ICA (<1.1). CT Abdomen and Pelvis was remarkable for focal pancreatitis with thickening in the peripancreatic space. …”
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“…Initial tests showed Hgb 10.9 g/dL, WBC 4.2k/uL (37% Neutrophil), total Ca 17.9 mg/dL, iCa 2.43 mmol/L, Mg 2.4 mg/dL, Phos 4.8 mg/dL, AST 102 IU/L, ALT 115 IU/L, albumin 4.4 g/dL, PTH 5.3 pg/mL (RR 10-65), 25-OHD 61.3 ng/mL, 1,25-(OH)(2)D 146 pg/mL (RR 19-79). …”
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