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  1. 88841
    “…Luciferase reporter assay was performed to illustrate the link between miRNA-27a and SYK. Lipopolysaccharide (LPS) and chronic social defeat stress (CSDS) depression models were established to investigate the antidepressant actions of isoliquiritin. …”
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    Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis
  2. 88842
    “…Quotations were selected to highlight or illustrate the themes and link the reported results to the empirical data. …”
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    Improving access to healthcare for paediatric sickle cell disease patients: a qualitative study on healthcare professionals’ views
  3. 88843
    “…CONCLUSIONS: This study illustrated ADSC-Exo attenuated the deposition of collagen, the trans-differentiation of fibroblasts-to-myofibroblasts, and the formation of hypertrophic scar by in vitro and in vivo experiments. …”
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    Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis
  4. 88844
    “…CONCLUSION: Caregivers of persons with chronic disease experience an excess humanistic and economic burden compared to the general population, with a greater burden confronting caregiver for adults with depression. These findings illustrate the far-reaching burden of depression on both the patient and the relatives who care for them. …”
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    Self-reported burden of caregiver of adults with depression: a cross-sectional study in five Western European countries
  5. 88845
    “…However, the exact mechanism of the cardiovascular protection activity of TI remains to be illustrated. In this study, the cardiovascular protective effect and its mechanism of TI were investigated. …”
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    Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway
  6. 88846
    “…Insecticides also performed better in an occupied house environment compared to semi-field constructed walls. This study illustrates the importance of collecting field-based observations to determine appropriate product active ingredient formulations and timing for recurring IRS cycles.…”
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    Variable residual activity of K-Othrine® PolyZone and Actellic® 300 CS in semi-field and natural conditions in the Democratic Republic of the Congo
  7. 88847
    por Liu, Long, Zhang, Jingze, Wu, Mei, Xu, Haiming
    Publicado 2021
    “…BACKGROUND: To illustrate the mechanism of miRNA and mRNA in coronary artery diseasen (CAD), differentially expressed microRNAs (DEmiRNAs) and genes (DEGs) were analyzed. …”
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    Identification of key miRNAs and mRNAs related to coronary artery disease by meta-analysis
  8. 88848
    “…METHODS: We present a local-scale entomological-risk score (“TriatoScore”) that leverages and builds upon information on the ecology-behavior and distribution-biogeography of individual triatomine bug species. We illustrate our approach by calculating TriatoScores for the 417 municipalities of Bahia state, Brazil. …”
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    TriatoScore: an entomological-risk score for Chagas disease vector control-surveillance
  9. 88849
    “…The flux sampling simulations allowed us to characterize intracellular metabolic flux states and illustrate the key parts of metabolism that likely determine the observed strain differences. …”
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    Metabolic flux sampling predicts strain-dependent differences related to aroma production among commercial wine yeasts
  10. 88850
    “…Overexpression of bna-miR159 in Arabidopsis resulted in decreased seed setting rate, and shortened siliques, illustrating that miR159 may regulate the fertility and silique development in rapeseed. …”
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    Identification of miRNAs and their target genes in genic male sterility lines in Brassica napus by small RNA sequencing
  11. 88851
    “…Sensitivity analyses illustrated that all results were stable. CONCLUSIONS: The efficacy of PD-1/PD-L1 inhibitor therapy in advanced NSCLC patients may be dependent on bTMB level. …”
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    The relationship between blood-based tumor mutation burden level and efficacy of PD-1/PD-L1 inhibitors in advanced non-small cell lung cancer: a systematic review and meta-analysis
  12. 88852
    por Boonmee, Saranyaphat, Wanasinghe, Dhanushka N., Calabon, Mark S., Huanraluek, Naruemon, Chandrasiri, Sajini K. U., Jones, Gareth E. B., Rossi, Walter, Leonardi, Marco, Singh, Sanjay K., Rana, Shiwali, Singh, Paras N., Maurya, Deepak K., Lagashetti, Ajay C., Choudhary, Deepika, Dai, Yu-Cheng, Zhao, Chang-Lin, Mu, Yan-Hong, Yuan, Hai-Sheng, He, Shuang-Hui, Phookamsak, Rungtiwa, Jiang, Hong-Bo, Martín, María P., Dueñas, Margarita, Telleria, M. Teresa, Kałucka, Izabela L., Jagodziński, Andrzej M., Liimatainen, Kare, Pereira, Diana S., Phillips, Alan J. L., Suwannarach, Nakarin, Kumla, Jaturong, Khuna, Surapong, Lumyong, Saisamorn, Potter, Tarynn B., Shivas, Roger G., Sparks, Adam H., Vaghefi, Niloofar, Abdel-Wahab, Mohamed A., Abdel-Aziz, Faten A., Li, Guo-Jie, Lin, Wen-Fei, Singh, Upendra, Bhatt, Rajendra P., Lee, Hyang Burm, Nguyen, Thuong T. T., Kirk, Paul M., Dutta, Arun Kumar, Acharya, Krishnendu, Sarma, V. Venkateswara, Niranjan, M., Rajeshkumar, Kunhiraman C., Ashtekar, Nikhil, Lad, Sneha, Wijayawardene, Nalin N., Bhat, Darbe J., Xu, Rong-Ju, Wijesinghe, Subodini N., Shen, Hong-Wei, Luo, Zong-Long, Zhang, Jing-Yi, Sysouphanthong, Phongeun, Thongklang, Naritsada, Bao, Dan-Feng, Aluthmuhandiram, Janith V. S., Abdollahzadeh, Jafar, Javadi, Alireza, Dovana, Francesco, Usman, Muhammad, Khalid, Abdul Nasir, Dissanayake, Asha J., Telagathoti, Anusha, Probst, Maraike, Peintner, Ursula, Garrido-Benavent, Isaac, Bóna, Lilla, Merényi, Zsolt, Boros, Lajos, Zoltán, Bratek, Stielow, J. Benjamin, Jiang, Ning, Tian, Cheng-Ming, Shams, Esmaeil, Dehghanizadeh, Farzaneh, Pordel, Adel, Javan-Nikkhah, Mohammad, Denchev, Teodor T., Denchev, Cvetomir M., Kemler, Martin, Begerow, Dominik, Deng, Chun-Ying, Harrower, Emma, Bozorov, Tohir, Kholmuradova, Tutigul, Gafforov, Yusufjon, Abdurazakov, Aziz, Xu, Jian-Chu, Mortimer, Peter E., Ren, Guang-Cong, Jeewon, Rajesh, Maharachchikumbura, Sajeewa S. N., Phukhamsakda, Chayanard, Mapook, Ausana, Hyde, Kevin D.
    Publicado 2021
    “…Fungal taxa described and illustrated in the present study include three new genera, 69 new species, one new combination, one reference specimen and 51 new records on new hosts and new geographical distributions. …”
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    Fungal diversity notes 1387–1511: taxonomic and phylogenetic contributions on genera and species of fungal taxa
  13. 88853
    “…We drew on this broad literature using illustrative examples from early PCOR experience and published literature to assess barriers and facilitators to implementing telehealth in populations at risk for disparities, using the active implementation framework to extract data. …”
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    Early Patient-Centered Outcomes Research Experience With the Use of Telehealth to Address Disparities: Scoping Review
  14. 88854
    “…Schools will be randomized to receive Strong & Deadly Futures, a web-based alcohol and drug prevention and social and emotional well-being program that delivers curriculum-aligned content over 6 lessons via an illustrated story, or health education as usual (control). …”
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    A Web-Based Alcohol and Other Drug Prevention Program (Strong & Deadly Futures) for Aboriginal and Torres Strait Islander School Students: Protocol for a Cluster Randomized Controlled Trial
  15. 88855
    “…We, therefore, aimed to illustrate the prevalence, severity, most common types, and major determinants of anemia among adults in Khuzestan, Iran, from 2016 to 2019. …”
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    Anemia prevalence, severity, types, and correlates among adult women and men in a multiethnic Iranian population: the Khuzestan Comprehensive Health Study (KCHS)
  16. 88856
    “…CONCLUSIONS: Our findings suggest that home stay is associated with symptom severity in MDD and demonstrate the importance of accounting for confounding factors in future studies. In addition, they illustrate that passive sensing of individuals with depression is feasible and could provide clinically relevant information to monitor the course of illness in patients with MDD.…”
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    The Association Between Home Stay and Symptom Severity in Major Depressive Disorder: Preliminary Findings From a Multicenter Observational Study Using Geolocation Data From Smartphones
  17. 88857
    “…METHODS: We used LandSyMM, a global gridded land use change model, to analyse the impact of recovery paths from COVID-19. The paths were illustrated by four scenarios that represent different pandemic severities (including a single or recurrent pandemic) and alternate modes of recovery, including a transition of food demand towards healthier diets that result in changes to the food system: (1) solidarity and celery, (2) nothing new, (3) fries and fragmentation, and (4) best laid plans. …”
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    How different COVID-19 recovery paths affect human health, environmental sustainability, and food affordability: a modelling study
  18. 88858
    “…GRAPHICAL ABSTRACT: A systematic graph illustrates the mechanism of dietary methionine and lysine influence on lipid metabolism and M(6)A. …”
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    Lipid metabolism and m(6)A RNA methylation are altered in lambs supplemented rumen-protected methionine and lysine in a low-protein diet
  19. 88859
    “…Moreover, in comparison with standard measures, higher resolution patterns in wearable heart rate recordings are better able to represent subtle physiological dynamics related to genomic risk for cardiometabolic disease (improvement of 11.9%-22.0% in Brier scores; P<.001). Finally, illustrative case studies reveal connections between these high-resolution phenotypes and actualized clinical events, even for borderline profiles lacking apparent cardiometabolic risk markers. …”
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    High-Resolution Digital Phenotypes From Consumer Wearables and Their Applications in Machine Learning of Cardiometabolic Risk Markers: Cohort Study
  20. 88860
    “…Furthermore, Apt-Pep@MUA.GNR-DOX illustrated higher cellular uptake toward EpCAM-overexpressing 4T1 cells compared to Pep@MUA.GNR-DOX. …”
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    Synthesis of doxorubicin-loaded peptosomes hybridized with gold nanorod for targeted drug delivery and CT imaging of metastatic breast cancer
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