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327881por Chemtob, Daniel, Rich, Rivka, Harel, Neta, Averick, Nechama, Schwartzberg, Eyal, Yust, Israel, Maayan, Shlomo, Grotto, Itamar, Gamzu, Ronni“…Since 2016, the MoH has fully covered this service and integrated it within the Israeli health system; this constitutes the major success of the PPP program. …”
Publicado 2019
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327882por Dyrbye, Liselotte N., Shanafelt, Tait D., Johnson, Pamela O., Johnson, Le Ann, Satele, Daniel, West, Colin P.“…After adjusting for age, sex, relationship and parental status, highest academic degree, practice setting, burnout, depression, and satisfaction with work-life integration, nurses who were more fatigued (for each point worsening, OR 1.22, 95% CI 1.10–1.37) were more likely to have had absenteeism while those who worked more hours (for each additional hour OR 0.98, 95% CI 0.96–1.00) were less likely to have had absenteeism. …”
Publicado 2019
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327883por van Santen, Jeffrey A., Jacob, Grégoire, Singh, Amrit Leen, Aniebok, Victor, Balunas, Marcy J., Bunsko, Derek, Neto, Fausto Carnevale, Castaño-Espriu, Laia, Chang, Chen, Clark, Trevor N., Cleary Little, Jessica L., Delgadillo, David A., Dorrestein, Pieter C., Duncan, Katherine R., Egan, Joseph M., Galey, Melissa M., Haeckl, F.P. Jake, Hua, Alex, Hughes, Alison H., Iskakova, Dasha, Khadilkar, Aswad, Lee, Jung-Ho, Lee, Sanghoon, LeGrow, Nicole, Liu, Dennis Y., Macho, Jocelyn M., McCaughey, Catherine S., Medema, Marnix H., Neupane, Ram P., O’Donnell, Timothy J., Paula, Jasmine S., Sanchez, Laura M., Shaikh, Anam F., Soldatou, Sylvia, Terlouw, Barbara R., Tran, Tuan Anh, Valentine, Mercia, van der Hooft, Justin J. J., Vo, Duy A., Wang, Mingxun, Wilson, Darryl, Zink, Katherine E., Linington, Roger G.“…The Natural Products Atlas has been developed under FAIR principles (Findable, Accessible, Interoperable, and Reusable) and is integrated with other emerging natural product databases, including the Minimum Information About a Biosynthetic Gene Cluster (MIBiG) repository, and the Global Natural Products Social Molecular Networking (GNPS) platform. …”
Publicado 2019
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327884por Lende, Tone Hoel, Austdal, Marie, Bathen, Tone Frost, Varhaugvik, Anne Elin, Skaland, Ivar, Gudlaugsson, Einar, Egeland, Nina G., Lunde, Siri, Akslen, Lars A., Jonsdottir, Kristin, Janssen, Emiel A. M., Søiland, Håvard, Baak, Jan P. A.“…Patients with ER-positive / T2 tumors and high tumor glutathione (≥1.09), high S-lactate (≥56.9), and high S-pyruvate (≥12.5) had inferior clinical outcomes regarding relapse-free survival, breast cancer-specific survival, and overall survival. Moreover, Integrated Pathway Analysis (IPA) in serum revealed activation of five major anabolic metabolic networks contributing to proliferation and growth. …”
Publicado 2019
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327885por de las Heras-Saldana, Sara, Clark, Samuel A., Duijvesteijn, Naomi, Gondro, Cedric, van der Werf, Julius H. J., Chen, Yizhou“…Therefore, here we show that integrating information from gene expression and GWAS studies can help to better understand the genetic mechanisms that determine variation in complex traits.…”
Publicado 2019
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327886por Leyna, Germana Henry, Makyao, Neema, Mwijage, Alexander, Ramadhan, Angela, Likindikoki, Samuel, Mizinduko, Mucho, Leshabari, Melkizedeck Thomas, Moen, Kåre, Mmbaga, Elia John“…This study therefore aimed at estimating the prevalence of HCV and associated risk factors among PWID in the largest metropolitan city in Tanzania to inform WHO elimination recommendations. METHODS: An integrated bio-behavioral survey using respondent-driven sampling was used to recruit PWID residing in Dar es Salaam, Tanzania. …”
Publicado 2019
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327887por Lai, Po-Ting, Lu, Wei-Liang, Kuo, Ting-Rung, Chung, Chia-Ru, Han, Jen-Chieh, Tsai, Richard Tzong-Han, Horng, Jorng-Tzong“…Finally, we implemented large margin context-aware convolutional neural network architecture to integrate context features and convolutional neural networks through the large margin function. …”
Publicado 2019
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327888por Chishtie, Jawad Ahmed, Babineau, Jessica, Bielska, Iwona Anna, Cepoiu-Martin, Monica, Irvine, Michael, Koval, Andriy, Marchand, Jean-Sebastien, Turcotte, Luke, Jeji, Tara, Jaglal, Susan“…CONCLUSIONS: VA is being increasingly used and integrated with emerging technologies to support decision making using large data sets. …”
Publicado 2019
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327889por Sokol, Randi, Albanese, Mark, Chew, Aaronson, Early, Jessica, Grossman, Ellie, Roll, David, Sawin, Greg, Wu, Dominic J., Schuman-Olivier, Zev“…METHODS: To create a blueprint delineating GBOT implementation, we integrated findings from a previously conducted and separately published systematic review of existing GBOT studies, conducted additional literature review, reviewed best practice recommendations and policies related to GBOT and organizational frameworks for implementing health systems change. …”
Publicado 2019
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327890por Cortese, Andrea, Lombardi, Raffaella, Briani, Chiara, Callegari, Ilaria, Benedetti, Luana, Manganelli, Fiore, Luigetti, Marco, Ferrari, Sergio, Clerici, Angelo M., Marfia, Girolama Alessandra, Rigamonti, Andrea, Carpo, Marinella, Fazio, Raffaella, Corbo, Massimo, Mazzeo, Anna, Giannini, Fabio, Cosentino, Giuseppe, Zardini, Elisabetta, Currò, Riccardo, Gastaldi, Matteo, Vegezzi, Elisa, Alfonsi, Enrico, Berardinelli, Angela, Kouton, Ludivine, Manso, Constance, Giannotta, Claudia, Doneddu, Pietro, Dacci, Patrizia, Piccolo, Laura, Ruiz, Marta, Salvalaggio, Alessandro, De Michelis, Chiara, Spina, Emanuele, Topa, Antonietta, Bisogni, Giulia, Romano, Angela, Mariotto, Sara, Mataluni, Giorgia, Cerri, Federica, Stancanelli, Claudia, Sabatelli, Mario, Schenone, Angelo, Marchioni, Enrico, Lauria, Giuseppe, Nobile-Orazio, Eduardo, Devaux, Jérôme, Franciotta, Diego“…We also provided preliminary evidence from a single patient about the pathogenicity of anti-Caspr1 IgG4, showing their ability to penetrate paranodal regions and disrupt the integrity of the Nfasc155/CNTN1/Caspr1 complex. CONCLUSIONS: Our findings confirm previous data on the tight clinico-serological correlation between antibodies to nodal/paranodal proteins and CIDP. …”
Publicado 2019
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327891por de Araujo, Leonardo Silva, Pessler, Kevin, Sühs, Kurt-Wolfram, Novoselova, Natalia, Klawonn, Frank, Kuhn, Maike, Kaever, Volkhard, Müller-Vahl, Kirsten, Trebst, Corinna, Skripuletz, Thomas, Stangel, Martin, Pessler, Frank“…Considering our previously reported association between free membrane phospholipids in cerebrospinal fluid (CSF) and CNS involvement in neuroinfections we evaluated phosphatidylcholine PC ae C44:6, an integral constituent of cell membranes, as diagnostic biomarker for bacterial meningitis. …”
Publicado 2020
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327892por Shi, Haoyue, Yang, Deshuang, Qiao, Jiajun, Sun, Rui, Li, Ruihan, Zhu, Chunlin, Jing, Ruiqing, Liu, Liping, Huang, Li, Li, Lin“…The secondary endpoints are the change in average systolic and diastolic blood pressure during the day and the night, the change in the rate at which blood pressure drops at night, assessment of target organ damage (heart rate variability, ankle–brachial pressure index, and pulse wave velocity), assessment of any improvement in symptoms (Hypertension Symptom Scale, syndrome integral scale in traditional Chinese medicine, Pittsburgh Sleep Quality Index Scale, Self-Rating Anxiety Scale, Self-Rating Depression Scale, and the 36-Item Short Form Health Survey), blood lipids, serum indicators of vascular function (changes in serum levels of ET-1, TXA2, NO, and PGI2), and safety indicators. …”
Publicado 2020
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327893por Kiebish, Michael A., Cullen, Jennifer, Mishra, Prachi, Ali, Amina, Milliman, Eric, Rodrigues, Leonardo O., Chen, Emily Y., Tolstikov, Vladimir, Zhang, Lixia, Panagopoulos, Kiki, Shah, Punit, Chen, Yongmei, Petrovics, Gyorgy, Rosner, Inger L., Sesterhenn, Isabell A., McLeod, David G., Granger, Elder, Sarangarajan, Rangaprasad, Akmaev, Viatcheslav, Srinivasan, Alagarsamy, Srivastava, Shiv, Narain, Niven R., Dobi, Albert“…Linear Regression and Bayesian computational approaches integrated with multi-omics, were used to select markers to predict biochemical recurrence (BCR). …”
Publicado 2020
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327894por Maynard-Paquette, Anne-Catherine, Poirier, Claude, Chartrand-Lefebvre, Carl, Dubé, Bruno-Pierre“…Ultrasonography can provide a non-invasive evaluation of the integrity of both peripheral muscles and diaphragm, but its use in patients with COPD is still being investigated. …”
Publicado 2020
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327895por Workman, Michael J., Gomes, Bruno, Weng, Ju-Lin, Ista, Linnea K., Jesus, Camila P., David, Mariana R., Ramalho-Ortigao, Marcelo, Genta, Fernando A., Matthews, Scott K., Durvasula, Ravi, Hurwitz, Ivy“…These results demonstrate its potential for incorporation in an integrated approach to larval source management of Ae. aegypti. …”
Publicado 2020
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327896por Köfalvi, Attila, Moreno, Estefanía, Cordomí, Arnau, Cai, Ning-Sheng, Fernández-Dueñas, Victor, Ferreira, Samira G., Guixà-González, Ramón, Sánchez-Soto, Marta, Yano, Hideaki, Casadó-Anguera, Verònica, Cunha, Rodrigo A., Sebastião, Ana Maria, Ciruela, Francisco, Pardo, Leonardo, Casadó, Vicent, Ferré, Sergi“…BACKGROUND: It has been hypothesized that heteromers of adenosine A(2A) receptors (A2AR) and cannabinoid CB(1) receptors (CB1R) localized in glutamatergic nerve terminals mediate the integration of adenosine and endocannabinoid signaling involved in the modulation of striatal excitatory neurotransmission. …”
Publicado 2020
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327897por Anari, Marziyeh, Stroehlein, Andreas J., Hall, Ross S., Chang, Bill C. H., Gasser, Robin B., Young, Neil D.“…Although the precise biological mechanisms underlying this adaptation are unknown, previous work indicated that Niemann-pick type C2 (NPC2)-like sterol-binding proteins might be integral in the host-parasite interplay. Expansions of this family in some invertebrates, such as arthropods, have shown functional diversification, including novel forms of chemoreception. …”
Publicado 2020
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327898Construction of a novel gene-based model for prognosis prediction of clear cell renal cell carcinomapor Zhang, Zedan, Lin, Enyu, Zhuang, Hongkai, Xie, Lu, Feng, Xiaoqiang, Liu, Jiumin, Yu, Yuming“…CONCLUSIONS: In our study, we constructed a gene-based model integrating clinical prognostic parameters to predict prognosis of ccRCC well, which might provide a reliable prognosis assessment tool for clinician and aid treatment decision-making in the clinic.…”
Publicado 2020
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327899por Heins, Anna-Lena, Reyelt, Jan, Schmidt, Marlen, Kranz, Harald, Weuster-Botz, Dirk“…The strains carry three different fluorescence proteins chromosomally integrated. Single cell growth is followed with EmeraldGFP (EmGFP)-expression together with the ribosomal promoter rrnB. …”
Publicado 2020
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327900por Medvedev, Melissa M., Tumukunde, Victor, Mambule, Ivan, Tann, Cally J., Waiswa, Peter, Canter, Ruth R., Hansen, Christian H., Ekirapa-Kiracho, Elizabeth, Katumba, Kenneth, Pitt, Catherine, Greco, Giulia, Brotherton, Helen, Elbourne, Diana, Seeley, Janet, Nyirenda, Moffat, Allen, Elizabeth, Lawn, Joy E.“…Quantitative and qualitative data will be integrated in a process evaluation. Cost data will be collected and used in economic modelling. …”
Publicado 2020
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