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  1. 328321
    “…BACKGROUND: Although current guidelines advocate early integration of palliative care, symptom burden and palliative care needs of patients at diagnosis of incurable cancer and along the disease trajectory are understudied. …”
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    Symptom Burden and Palliative Care Needs of Patients with Incurable Cancer at Diagnosis and During the Disease Course
  2. 328322
    “…Following viral RNA quantification, sequencing was performed using the Ion AmpliSeq SARS-CoV-2 Research Panel on the Genexus Integrated Sequencer, an automated technology for library preparation and sequencing. …”
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    SARS-CoV-2 complete genome sequencing from the Italian Campania region using a highly automated next generation sequencing system
  3. 328323
    “…BACKGROUND: Although risk prediction has become an integral part of clinical practice guidelines for cardiovascular disease (CVD) prevention, multiple studies have shown that patients’ risk still plays almost no role in clinical decision-making. …”
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    Understanding providers’ attitudes and key concerns toward incorporating CVD risk prediction into clinical practice: a qualitative study
  4. 328324
    “…This was investigated in a multicenter, double-blind, randomized controlled trial involving 468 Chinese patients with active RA [disease activity score (DAS)-28 > 3.2] treated with QRHXD/QRHXEP (TCM group), methotrexate plus hydroxychloroquine [Western medicine (WM) group], or both [integrative medicine (IM) group]. Patients were followed up for 24 weeks. …”
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    Traditional Chinese Medicine Qingre Huoxue Treatment vs. the Combination of Methotrexate and Hydroxychloroquine for Active Rheumatoid Arthritis: A Multicenter, Double-Blind, Randomized Controlled Trial
  5. 328325
    por Wang, Zhi, Tu, Lei, Chen, Minfeng, Tong, Shiyu
    Publicado 2021
    “…CONCLUSIONS: Our study firstly integrated multiple TME-related genes to set up a risk predictive model. …”
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    Identification of a tumor microenvironment-related seven-gene signature for predicting prognosis in bladder cancer
  6. 328326
    “…Schema modes are either integrated or dissociative states of mind, including intense emotional states, efforts to regulate emotions, or self-reflective evaluative thought processes. …”
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    Schema modes and their associations with emotion regulation, mindfulness, and self-compassion among patients with personality disorders
  7. 328327
    “…The RRA method was used to integrate and screen differentially expressed genes (DEGs) between CC and normal samples. …”
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    SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma
  8. 328328
    “…Participants identified various enablers and opportunities for implementing a rights-based approach such as grass-roots advocacy efforts to raise awareness of the issue, integrating human rights into government frameworks and community projects and the political will to support action aligned with sustainable development. …”
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    Problems, policy and politics – perspectives of public health leaders on food insecurity and human rights in Australia
  9. 328329
    “…Two independent reviewers screened texts, and extracted and coded data guided by the Integrated Sustainability Framework, an existing multi-level sustainability-specific framework that assesses factors of sustainment. …”
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    Barriers and facilitators influencing the sustainment of health behaviour interventions in schools and childcare services: a systematic review
  10. 328330
    “…The additional value of integration of the e-Health intervention in primary care might be a logical next step. …”
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    Women’s adoption of a web-based intervention for stress urinary incontinence: a qualitative study
  11. 328331
    “…Nevertheless, these indexes were paucity of robustness (P >0.05) when integrating with 38 most recurrence-related radiomics signatures for developing the comprehensive nomogram. …”
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    Peritumoral Dilation Radiomics of Gadoxetate Disodium-Enhanced MRI Excellently Predicts Early Recurrence of Hepatocellular Carcinoma without Macrovascular Invasion After Hepatectomy
  12. 328332
    por Pollard, Teresa, Howard, Natasha
    Publicado 2021
    “…Asylum-seekers and refugees (ASR) may experience traumatic events pre-departure, life-threating circumstances on their journeys, and difficulties integrating into host countries related to immigration policies, social isolation, poor living conditions, and unemployment, all of which can significantly affect their mental health. …”
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    Mental healthcare for asylum-seekers and refugees residing in the United Kingdom: a scoping review of policies, barriers, and enablers
  13. 328333
    “…In this study, we aim to examine the adipogenic differentiation of hBMSCs within soft or stiff scaffolds and investigate the molecular mechanism mediating the response of hBMSCs to substrate stiffness in 3D culture, specifically the involvement of the integral membrane protein, caveolin-1 (CAV1), known to regulate signaling in MSCs via compartmentalizing and concentrating signaling molecules. …”
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    Caveolin-1 mediates soft scaffold-enhanced adipogenesis of human mesenchymal stem cells
  14. 328334
    “…We aim to compare the effects of double- and single-row arthroscopic rotator cuff repairs (ARCR) on repair integrity (RI) and acromiohumeral distance (AHD). METHODS: In this observational study, we retrospectively identified 98 patients with degenerative rotator cuff tear treated with arthroscopic rotator cuff repair between 2016 and 2019. …”
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    Increased acromiohumeral distance in a double-row arthroscopic rotator cuff surgery compared to a single-row surgery after 12 months
  15. 328335
    “…We speculate that the mobilization of SATB2 and increased enrichment of H3K9me2 may be components of a nuclear stress response that preserve chromatin integrity and interactions under prolonged oxidative stress. …”
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    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
  16. 328336
    “…Long molecule sequencing at the edited site and plasmid-specific PCRs did not reveal structural variations and/or plasmid integration events in edited samples. Furthermore, an in-depth analysis of de novo mutations across the edited and non-edited cloned calves revealed that the mutation frequency and spectra were unaffected by editing status. …”
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    The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis
  17. 328337
    “…CONCLUSIONS: These findings suggest that the desirability, feasibility, and viability of eHealth interventions for caregivers of people with dementia are linked to their integration into larger structures, their ownership and support of content internally, their development of information and communication technology services externally, and their offer of fixed, low pricing. …”
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    Business Models of eHealth Interventions to Support Informal Caregivers of People With Dementia in the Netherlands: Analysis of Case Studies
  18. 328338
    por Larsen, Anna, Tele, Albert, Kumar, Manasi
    Publicado 2021
    “…BACKGROUND: In designing, adapting, and integrating mental health interventions, it is pertinent to understand patients’ needs and their own perceptions and values in receiving care. …”
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    Mental health service preferences of patients and providers: a scoping review of conjoint analysis and discrete choice experiments from global public health literature over the last 20 years (1999–2019)
  19. 328339
    “…A pilot randomized trial was done to test the feasibility integrating virtual reality (VR) into standard behavioral weight loss treatment. …”
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    Feasibility of a virtual reality-based approach to improve behavioral weight management outcomes
  20. 328340
    “…In this paper, we present our latest open-source protein tertiary structure prediction system—MULTICOM2, an integration of template-based modeling (TBM) and template-free modeling (FM) methods. …”
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    MULTICOM2 open-source protein structure prediction system powered by deep learning and distance prediction
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