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328501“…Although there is some influence of media opacity, the exact nature is not clearly understood and may have a crucial interaction with genetic and other environmental factors. Genetic testing integrated with biometric analysis is recommended for further understanding of the ocular growth and development.…”
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328502“…CONCLUSIONS: This study demonstrated that a PYL curriculum to improve HIV knowledge integrated into routine adolescent HIV clinic in Tanzania was feasible, acceptable, and improved knowledge while also benefiting peer leaders, thus providing evidence to continue to support efforts to scale and sustain PYL interventions for YLWH. …”
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328503por Kotredes, Kevin P., Oblak, Adrian, Pandey, Ravi S., Lin, Peter Bor-Chian, Garceau, Dylan, Williams, Harriet, Uyar, Asli, O’Rourke, Rita, O’Rourke, Sarah, Ingraham, Cynthia, Bednarczyk, Daria, Belanger, Melisa, Cope, Zackary, Foley, Kate E., Logsdon, Benjamin A., Mangravite, Lara M., Sukoff Rizzo, Stacey J., Territo, Paul R., Carter, Gregory W., Sasner, Michael, Lamb, Bruce T., Howell, Gareth R.“…To create more translatable mouse models, MODEL-AD (Model Organism Development and Evaluation for Late-onset AD) groups are identifying and integrating disease-relevant, humanized gene sequences from public databases beginning with APOEε4 and Trem2*R47H, two of the most powerful risk factors present in human LOAD populations. …”
Publicado 2021
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328504“…Issues involving school were described, ranging from difficulties integrating their child into mainstream schooling and the impact of treatment on participation in school and extracurricular activities. …”
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328505por Zhang, Feng-Li, Yang, Ya-Lin, Zhang, Zhen, Yao, Yuan-Yuan, Xia, Rui, Gao, Chen-Chen, Du, Dong-Dong, Hu, Juan, Ran, Chao, Liu, Zhen, Zhou, Zhi-Gang“…In conclusion, the recombinant bacteria AM-ZHY1 has the capacity to maintain intestinal health by protecting intestinal integrity and improving intestinal flora structure and improving fatty liver disease by inhibiting lipid synthesis and absorption. …”
Publicado 2021
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328506por Tamihardja, Jörg, Cirsi, Sinan, Kessler, Patrick, Razinskas, Gary, Exner, Florian, Richter, Anne, Polat, Bülent, Flentje, Michael“…METHODS: Twenty-three patients with localized prostate cancer treated with moderately hypofractionated prostate radiotherapy with simultaneous integrated boost (SIB) between December 2016 and February 2020 were retrospectively analyzed. …”
Publicado 2021
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328507por Chuter, Vivienne H., Spink, Martin J., David, Michael, Lanting, Sean, Searle, Angela“…CONCLUSIONS: Participants presenting with two or more factors affecting foot biomechanics displayed higher peak pressures and pressure time integrals in all foot regions compared to those with less than two factors. …”
Publicado 2021
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328508por Oh, Jiwon, Arbour, Nathalie, Giuliani, Fabrizio, Guenette, Melanie, Kolind, Shannon, Lynd, Larry, Marrie, Ruth Ann, Metz, Luanne M., Patten, Scott B., Prat, Alexandre, Schabas, Alice, Smyth, Penelope, Tam, Roger, Traboulsee, Anthony, Yong, V. Wee“…In a subset of participants within 5–10 years of disease onset (n = 500), blood, cerebrospinal fluid, and research MRIs will be collected allowing an integrated, in-depth evaluation of factors contributing to progression in MS from multiple perspectives. …”
Publicado 2021
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328509por Gauthier-Loiselle, Marjolaine, Cloutier, Martin, Toro, Walter, Patel, Anish, Shi, Sherry, Davidson, Mikhail, Bischof, Matthias, LaMarca, Nicole, Dabbous, Omar“…The indicated regimen requires intrathecal injections every 4 months, following the first four injections during the loading phase. Adherence is integral to treatment success. Adherence to nusinersen may pose particular challenges as most patients with SMA are young children who require complex multidisciplinary care (including ongoing intrathecal treatment administration and potential specialized anesthetic and surgical procedures) at specialized centers. …”
Publicado 2021
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328510por Zhang, Shuxian, Li, Huayun, Xu, Qinyan, Wang, Chao, Li, Xue, Sun, Jiawei, Wang, Yaqi, Sun, Tong, Wang, Qianqian, Zhang, Chengcheng, Wang, Jili, Jia, Xize, Sun, Xihe“…CONCLUSIONS: The results showed that the superior frontal gyrus and middle frontal gyrus were involved in the integration and processing of pain signals. In addition, the abnormal spontaneous neural activity in TTH patients was frequency-specific. …”
Publicado 2021
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328511“…It is important to keep measuring the health outcomes of the populations which are “invisible” in national statistics, in order to identify the groups in most need of integration and access to services. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-021-04183-9.…”
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328512Adoption of Machine Learning Systems for Medical Diagnostics in Clinics: Qualitative Interview Study“…However, despite the high potential of ML, only a few ML systems have been deployed in clinics yet, as their adoption process differs significantly from the integration of prior health information technologies given the specific characteristics of ML. …”
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328513por Sugg, Holly V. R., Russell, Anne-Marie, Morgan, Leila M., Iles-Smith, Heather, Richards, David A., Morley, Naomi, Burnett, Sarah, Cockcroft, Emma J., Thompson Coon, Jo, Cruickshank, Susanne, Doris, Faye E., Hunt, Harriet A., Kent, Merryn, Logan, Philippa A., Rafferty, Anne Marie, Shepherd, Maggie H., Singh, Sally J., Tooze, Susannah J., Whear, Rebecca“…We analysed quantitative data descriptively and qualitative data using Framework Analysis, integrating data in side-by-side comparison tables. …”
Publicado 2021
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328514por Ajjarapu, Suchitra Maheswari, Tiwari, Apoorv, Taj, Gohar, Singh, Dev Bukhsh, Singh, Sakshi, Kumar, Sundip“…BACKGROUND: Ovarian cancer is the world’s dreaded disease and its prevalence is expanding globally. The study of integrated molecular networks is crucial for the basic mechanism of cancer cells and their progression. …”
Publicado 2021
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328515por Wan, Guoxing, Chen, Peinan, Sun, Xue, Cai, Xiaojun, Yu, Xiongjie, Wang, Xianhe, Cao, Fengjun“…METHODS: The present study integrating several transcription profiling datasets aimed to identify key genes associated with AIC by weighted correlation network analysis (WGCNA) and differentially expressed analysis (DEA) and also constructed miRNA-transcription factor-gene regulatory network. …”
Publicado 2021
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328516“…METHODS: GSE40595 (38 samples), GSE18520 (63 samples), GSE26712 (195 samples), TCGA (321 samples) and GTEx (88 samples) were integrated to screen differential expressed genes (DEGs) of HGSOC. …”
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328517“…DNAm-driven genes were identified by integrating analyses of gene expression and DNA methylation data. …”
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328518por Pesut, Barbara, Thorne, Sally, Wright, David Kenneth, Schiller, Catharine, Huggins, Madison, Puurveen, Gloria, Chambaere, Kenneth“…Although many participants described a degree of integration between MAID and palliative care services, there remained ongoing tensions around equitable access to both. …”
Publicado 2021
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328519“…CONCLUSIONS: Public health monitoring and reporting with an intersectionality-informed and gender-equitable perspective might benefit from an integration of further sex/gender related aspects into quantitative analyses in order to detect population subgroups most affected by non-DVI. …”
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328520por Regina, Poß-Doering, Martin, Hegelow, Milena, Borchers, Mechthild, Hartmann, Johannes, Kruse, Hanna, Kampling, Gereon, Heuft, Carsten, Spitzer, Beate, Wild, Joachim, Szecsenyi, Hans-Christoph, Friederich“…CONCLUSIONS: The findings contribute to understanding the integration of the delivered structural reform into daily care processes and provide an indication about reached targets and potential improvements. …”
Publicado 2021
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