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  1. 328621
    “…This major milestone toward a complete tree of life for all flowering plant species opens doors to a highly integrated future for angiosperm phylogenomics through the systematic sequencing of standardized nuclear markers. …”
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    A Comprehensive Phylogenomic Platform for Exploring the Angiosperm Tree of Life
  2. 328622
    “…This collated caregiver knowledge is a call for all stakeholders—academics, policy makers, and practitioners—to take note of these specific challenges, and to ensure that caregiver voices are both heard and fully integrated within the emerging digital health agenda.…”
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    Understanding Current Needs and Future Expectations of Informal Caregivers for Technology to Support Health and Well-being: National Survey Study
  3. 328623
    por Blandino, Alice, Scherer, Dominique, Rounge, Trine B., Umu, Sinan U., Boekstegers, Felix, Barahona Ponce, Carol, Marcelain, Katherine, Gárate-Calderón, Valentina, Waldenberger, Melanie, Morales, Erik, Rojas, Armando, Munoz, César, Retamales, Javier, de Toro, Gonzalo, Barajas, Olga, Rivera, María Teresa, Cortés, Analía, Loader, Denisse, Saavedra, Javiera, Gutiérrez, Lorena, Ortega, Alejandro, Bertrán, Maria Enriqueta, Gabler, Fernando, Campos, Mónica, Alvarado, Juan, Moisán, Fabrizio, Spencer, Loreto, Nervi, Bruno, Carvajal-Hausdorf, Daniel E., Losada, Héctor, Almau, Mauricio, Fernández, Plinio, Gallegos, Ivan, Olloquequi, Jordi, Fuentes-Guajardo, Macarena, Gonzalez-Jose, Rolando, Bortolini, Maria Cátira, Gallo, Carla, Linares, Andres Ruiz, Rothhammer, Francisco, Lorenzo Bermejo, Justo
    Publicado 2022
    “…Few studies have investigated the association between individual genotypes and lncRNA expression. Here we integrate three separate datasets with information on lncRNA expression only, both lncRNA expression and genotype, and genotype information only to identify circulating lncRNAs associated with the risk of gallbladder cancer (GBC) using robust linear and logistic regression techniques. …”
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    Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression
  4. 328624
    “…Percent agreement and kappa between RTRI- and LAg EIA-based RITAs were >90% and >0.65 respectively indicating substantial agreement between the RITAs.This was the first field evaluation of an RTRI in sub-Saharan Africa, which demonstrated good performance of the assay and feasibility of integrating RTRI into routine HIV testing services for real-time surveillance of recent HIV infection.…”
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    Performance of a novel rapid test for recent HIV infection among newly-diagnosed pregnant adolescent girls and young women in four high-HIV-prevalence districts—Malawi, 2017–2018
  5. 328625
    “…By overlapping the results from the bioinformatics algorithms, tumor-suppressor bridging integrator-1 (BIN1) was found to be a main downstream target of the SNHG10/miR-200a-3p axis. …”
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    Long non-coding RNA SNHG10 upregulates BIN1 to suppress the tumorigenesis and epithelial–mesenchymal transition of epithelial ovarian cancer via sponging miR-200a-3p
  6. 328626
    “…Agatston score, mean FAI, and coronary stenosis severity were independent CCTA predictors of the presence of non-IR UMI. The integrated CCTA assessment may help identify the presence of non-IR UMI before urgent PCI.…”
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    Coronary Computed Tomography Angiographic Predictors of Non-culprit Territory Unrecognized Myocardial Infarction Assessed by Cardiac Magnetic Resonance in Non-ST-elevation Acute Coronary Syndrome
  7. 328627
    “…BACKGROUND: Transcription, metabolism and DNA damage response are tightly regulated to preserve the genomic integrity, and O-GlcNAc transferase (OGT) is positioned to connect the three. …”
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    O-GlcNAc transferase couples MRE11 to transcriptionally active chromatin to suppress DNA damage
  8. 328628
    “…Qualitative data will be thematically analyzed using sensitizing concepts from the Consolidated Framework for Implementation Research and integrated with the quantitative results using a joint display. …”
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    Implementing traumatic brain injury screening in behavioral healthcare: protocol for a prospective mixed methods study
  9. 328629
    “…Interventions to mitigate these challenges should focus on strengthening programming for the community and home-based care models and integrating malaria messages into Covid-19-related communication. …”
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    The impact of Covid-19 on malaria services in three high endemic districts in Rwanda: a mixed-method study
  10. 328630
    “…Furthermore, through integrated analysis of protein-protein interaction (PPI) network and co-expression network, fifteen genes involved in the neuroactive ligand-receptor interaction and WNT signaling pathways were identified, including KNG1, LPAR2, LPAR3, NPY, PLCB1, AVPR1B, GHSR, GRM3, HTR5A, FSHB, FSHR, WNT11, WNT5A, WIF1, and WNT7B, which could play crucial roles in the development of goose external genitalia. …”
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    Comparative transcriptome analysis identifies crucial candidate genes and pathways in the hypothalamic-pituitary-gonadal axis during external genitalia development of male geese
  11. 328631
    “…The inclusion of DPG and SvO(2) improved risk prediction compared with using SHFM [net classification improvement (NRI): 0.468 (0.161–0.752); integrated discriminatory index (IDI): 0.092 (0.035–0.171); likelihood ratio test: P < 0.001] or MAGGIC [NRI: 0.298 (0.106–0.615); IDI: 0.084 (0.033–0.151); likelihood ratio: P < 0.001] scores alone. …”
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    Risk prediction in pulmonary hypertension due to chronic heart failure: incremental prognostic value of pulmonary hemodynamics
  12. 328632
    “…But it was negatively correlated with PD, DA and integral radius (IR) (P < 0.05). Also, IOP was negatively correlated with A2L and IR (P < 0.05). …”
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    Correlation of myopia onset and progression with corneal biomechanical parameters in children
  13. 328633
    “…METHODS: Insurance claims data from the Symphony Health Solutions Integrated Dataverse (05/2017–05/2019) were retrospectively analyzed for patients diagnosed with HD (ICD-10-CM code G10). …”
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    Real-World Adherence to Tetrabenazine or Deutetrabenazine Among Patients With Huntington’s Disease: A Retrospective Database Analysis
  14. 328634
    “…Studies suggest that CIA may be uniquely situated to benefit from permanent integration of virtual care into regular practice for both new and follow-up appointments. …”
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    Telemedicine in allergy/immunology in the era of COVID-19: a Canadian perspective
  15. 328635
    “…It is highly recommended to integrate maternal and child health programmes with the ongoing health policies to improve the situation while taking additional care of the young pregnant mother and their nutritional health.…”
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    Decadal change in the association between the status of young mother’s Body Mass Index and anaemia with child low birth weight in India
  16. 328636
    “…Participants generally preferred the CBO for more professional, unbiased staff attitudes that respect patients’ integrity, confidentiality and privacy. Most participants thought that in case the government is non-cooperative, CBOs should work in the interest of HPV eradication and generate funds through international funding. …”
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    Human Papillomavirus associated prevention: knowledge, attitudes, and perceived risks among men who have sex with men and transgender women in Pakistan: a qualitative study
  17. 328637
    “…A Seasonal Autoregressive Integrated Moving Average (SARIMA) model was used to predict the monthly dengue incidence from March 2020 to April 2021 for each of the country’s 25 districts based on five years of pre-pandemic data, and compared with the actual recorded incidence of dengue during this period. …”
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    Reduced dengue incidence during the COVID-19 movement restrictions in Sri Lanka from March 2020 to April 2021
  18. 328638
    “…CONCLUSION: The BENITA (Bewegungs- und Ernährungsintervention bei Ovarialkrebs) study demonstrated the safety and acceptance of an exercise and nutrition intervention integrated into first-line therapy and follow-up care of ovarian cancer. …”
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    Randomised controlled trial testing the feasibility of an exercise and nutrition intervention for patients with ovarian cancer during and after first-line chemotherapy (BENITA-study)
  19. 328639
    “…However, the exact molecular mechanisms of m6A epigenetic regulation in breast cancer remain largely unknown and need to be fully elucidated. METHODS:  The integrating bioinformatics analyses were used to screen clinical relevance and dysregulated m6A “reader” protein YTHDF1 in breast cancer from TCGA databases, which was further validated in a cohort of clinical specimens. …”
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    YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner
  20. 328640
    “…Moreover, a nomogram was developed by integrating risk score from the prognostic model with clinicopathological parameters. …”
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    A novel prognostic model for hepatocellular carcinoma based on 5 microRNAs related to vascular invasion
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