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  1. 328661
    “…The frequency and distribution of EGFR ex20ins mutations between Chinese and Western LUAD patients were also compared by integrating the data of this study and the data of previous studies. …”
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    Clinicopathologic and molecular characteristics of Chinese lung adenocarcinoma patients with EGFR exon 20 insertion mutations
  2. 328662
    “…To better our understanding of interactions between host, diet, and microbiota in finfish and how those interactions may vary across mucosal tissue, we used an integrative approach to characterize and compare immune biomarkers and microbiota across three mucosal tissues (skin, gill, and gut) in Atlantic salmon receiving a control diet or diets supplemented with mannan-oligosaccharides, coconut oil, or both. …”
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    Functional feeds marginally alter immune expression and microbiota of Atlantic salmon (Salmo salar) gut, gill, and skin mucosa though evidence of tissue-specific signatures and host–microbe coadaptation remain
  3. 328663
    “…This was further supported by microbe-metabolite integration which identified functionally relevant taxa driving disease outcome, of which Sphingobacterium and Bd were most influential in wild epizootic dynamics. …”
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    Microbiome function predicts amphibian chytridiomycosis disease dynamics
  4. 328664
    “…Data on implementation processes were collected during implementation meetings with nursing home leadership and were analyzed via content analysis. Findings were integrated using a complementary approach. RESULTS: The ISBAR instrument and the INTERCARE nurse role were considered acceptable, feasible, and taken up by > 70% of care workers. …”
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    Implementation of a complex intervention to reduce hospitalizations from nursing homes: a mixed-method evaluation of implementation processes and outcomes
  5. 328665
    por Chen, Ruirong, Su, Sheng, Shu, Haihua
    Publicado 2022
    “…The published papers are not yet fully integrated and do not adequately address the impact and safety of the RIB on postoperative pain. …”
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    Efficacy and safety of rhomboid intercostal block for analgesia in breast surgery and thoracoscopic surgery: a meta-analysis
  6. 328666
    “…METHODS: We leveraged transcriptomic data of colon cancer from the existing datasets and constructed immune-related lncRNA (irlncRNA) pairs. After integrating with clinical survival data, we performed differential analysis and identified 11 irlncRNAs signature using Lasso regression analysis. …”
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    Construction of immune-related lncRNA signature to predict aggressiveness, immune landscape, and drug resistance of colon cancer
  7. 328667
    “…However, the rich data generated via EMA have not been frequently examined in T1D or integrated with machine learning analytic approaches. …”
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    Using Momentary Assessment and Machine Learning to Identify Barriers to Self-management in Type 1 Diabetes: Observational Study
  8. 328668
    “…IVC embryos and second by an integrative transcriptome analysis including in vivo control embryos. …”
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    Unveiling how vitrification affects the porcine blastocyst: clues from a transcriptomic study
  9. 328669
    “…There is a paucity of comprehensive surveys of biodiversity integrating morphological and molecular species identification conducted within the border of Laos and Cambodia. …”
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    Morphological and molecular identification reveals a high diversity of Anopheles species in the forest region of the Cambodia–Laos border
  10. 328670
    “…BACKGROUND: Integral membrane protein 2A (ITM2A) is a transmembrane protein expressed in a variety of tissues; little is known about its function, particularly in the brain. …”
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    Exploring ITM2A as a new potential target for brain delivery
  11. 328671
    “…We evaluated factors associated with weight gain of ≥ 15 pounds during the pandemic within an integrated health care system. METHODS: We included adults ages 18 and above with at least one weight measurement before the pandemic (March 19, 2019–March 19, 2020) and another measurement after COVID-19 vaccines became available, more than 9 months into the pandemic (December 14, 2020–December 14, 2021). …”
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    Factors associated with weight gain during the COVID-19 pandemic
  12. 328672
    “…The plastid rpl32 was integrated into the nuclear-encoded SODcp gene. Our findings suggested that the transferred rpl32 had undergone subfunctionalization by duplication rather than alternative splicing. …”
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    Gene loss, genome rearrangement, and accelerated substitution rates in plastid genome of Hypericum ascyron (Hypericaceae)
  13. 328673
    “…Thus, the strategy can be integrated with the essential services provided by primary health care units at the village and health post level in rural settings.…”
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    Trained health extension workers correctly identify high blood pressure in rural districts of northwest Ethiopia: a diagnostic accuracy study
  14. 328674
    “…These results suggest that this family of plasmids can integrate various foreign genes and is transmissible among C. perfringens strains. …”
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    Analysis of the complete genome sequences of Clostridium perfringens strains harbouring the binary enterotoxin BEC gene and comparative genomics of pCP13-like family plasmids
  15. 328675
    “…MATERIALS AND METHODS: This is a retrospective study conducted with 2016–2018 data from the HealthCore Integrated Research Database, consisting of commercial and Medicare-insured adult patients with a cancer diagnosis using ICI in the USA. …”
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    Immune checkpoint inhibitors: immune-related adverse events, healthcare utilization, and costs among commercial and Medicare Advantage patients
  16. 328676
    por Kurhaluk, Natalia, Tkachenko, Halyna
    Publicado 2022
    “…The statistical SS test allowed us to draw the following conclusions on the role of each lysosomal parameter analyzed as an integral model: NAG > AcP > β-GD > β-GR > AAP > LAP.…”
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    Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet
  17. 328677
    “…In conclusion, DNA methylation features of age acceleration are an integrative part of the methylation-based tumor classification (RTK I, RTK II, MES), while patient age seems hardly reflected in the glioblastoma DNA methylome. …”
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    DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome—including in elderly patients
  18. 328678
    “…A qualitative process evaluation will also be undertaken to explore the acceptability of the BASIL(+) intervention, as well as barriers and enablers to integrating the intervention into participants’ existing health and care support, and the impact of the intervention on participants’ mood and general wellbeing in the context of the COVID-19 restrictions. …”
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    Behavioural Activation for Social IsoLation (BASIL(+)) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial
  19. 328679
    “…We also validated some key findings with a batch integration analysis of published single cell RNA sequencing data. …”
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    Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses
  20. 328680
    “…EWS pertaining to dengue outbreaks is imperative; given the fact that dengue is linked to environmental factors owing to its dominance in the tropics. Prediction is an integral part of EWS, which is dependent on several factors, in particular, climate, geography, and environmental factors. …”
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    Prediction of dengue fever outbreaks using climate variability and Markov chain Monte Carlo techniques in a stochastic susceptible-infected-removed model
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