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  1. 329241
    “…The prevailing model used to explain this selective neurodegeneration—prion-like Tau spread—has key limitations and is not easily integrated with other defining sAD features. Instead, we propose that in humans Tau hyperphosphorylation occurs locally via disruption in ApoER2-Dab1 signaling and thus the presence of ApoER2 in neuronal membranes confers vulnerability to degeneration. …”
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    ApoER2-Dab1 disruption as the origin of pTau-related neurodegeneration in sporadic Alzheimer’s disease
  2. 329242
    “…A GO (gene ontology) enrichment analysis of target proteins related to AP and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway annotation was performed using the DAVID (The Database for Annotation, Visualization, and Integrated Discovery) database. Finally, the “Herbal-Compound-Target” network was constructed using Cytoscape software. …”
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    Predicting and Validating the Mechanism of Qingyi II Granules in the Treatment of Acute Pancreatitis by Network Pharmacology
  3. 329243
    “…Predictive models are to be integrated into actual clinical decisions. METHODS: Patient information was collected from December 01, 2014 to December 01, 2022 from the Department of Urology, The First Affiliated Hospital of Nanchang University. …”
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    Development, comparison, and validation of four intelligent, practical machine learning models for patients with prostate-specific antigen in the gray zone
  4. 329244
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    Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT(1A) and 5-HT(7A) Receptors
  5. 329245
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    Synthesis, Characterization, DNA/HSA Interaction, and Cytotoxic Activity of a Copper(II) Thiolate Schiff Base Complex and Its Corresponding Water-Soluble Stable Sulfinato–O Complex Containing Imidazole as a Co-ligand
  6. 329246
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    Traditional Chinese medicine for the COVID-19 pandemic: An online cross-sectional survey among health care workers
  7. 329247
    “…In addition, antibiotic prescription data for patients with influenza hospitalized from 2018 to 2021 were compared with those for patients with COVID-19, using an integrated database from Korea Disease Control and Prevention Agency-COVID19-National Health Insurance Service cohort (K-COV-N cohort), which was partially adjusted and obtained from October 2020 to December 2021. …”
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    Antibiotic Prescription in Patients With Coronavirus Disease 2019: Analysis of National Health Insurance System Data in the Republic of Korea
  8. 329248
    “…An example is CsrA, a global posttranscriptional regulator that modulates carbon metabolism and biofilm formation. CsrA integrates alternative carbon usage metabolism cues to activate c-di-GMP biosynthesis through HmsT. …”
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    CsrA-Mediated Translational Activation of the hmsE mRNA Enhances HmsD-Dependent C-di-GMP-Enabled Biofilm Production in Yersinia pestis
  9. 329249
    “…These harsh ecosystems, with their integral players, such as HGT and endosymbionts, significantly impact the enrichment of life on Earth and the carbon cycle in the ocean.…”
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    Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems
  10. 329250
    “…To exemplarily characterize the mesenchymal subtype of HGSOC and elucidate targeted treatment opportunities, we integrated bulk and single-cell RNA data analysis, and investigated the composition of the TME, its cell–cell communication, and transcription factor regulation. …”
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    In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients
  11. 329251
    “…This finding has particular importance for the use of integrated versus structured refuges. ABSTRACT: Exposure of lepidopteran pests to Bacillus thuringiensis (Bt) proteins has been shown to affect the behavior of larvae, including increased movement and avoidance of Bt-expressing plants or diet. …”
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    Movement of Striacosta albicosta (Smith) (Lepidoptera: Noctuidae) Larvae on Transgenic Bt and Non-Bt Maize
  12. 329252
    “…Social well-being was measured as social support, social participation, social relationships, community support, social integration, or loneliness. RESULTS: A total of 41 studies were retrieved from 18 969 citations; 37 studies were eligible for meta-analysis. …”
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    Health Care Utilization Following Interventions to Improve Social Well-Being: A Systematic Review and Meta-analysis
  13. 329253
    “…Further well-designed RCTs and integrated studies are required to determine the optimal treatment. …”
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    Second-line therapy for patients with steroid-refractory aGVHD: systematic review and meta-analysis of randomized controlled trials
  14. 329254
    “…Several studies reported on the differential expression of other pro- and antiangiogenic factors in patients with AUB-E, suggesting aberrant vascular maturation and impaired vessel integrity. Overall, endometrial microvessel density (MVD) was comparable in patients with AUB-E and controls. …”
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    Angiogenesis in abnormal uterine bleeding: a narrative review
  15. 329255
    “…Residents have reported quick integration and predictable umbilical positioning with this technique. …”
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    Natural Umbilicoplasty Without Visible Scarring: An Easily Taught and Reproducible Technique
  16. 329256
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    The Metal-Oxide Nanoparticle–Aqueous Solution Interface Studied by Liquid-Microjet Photoemission
  17. 329257
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    Kinetic and Thermodynamic Enhancement of Low-Temperature Oxygen Release from Strontium Ferrite Perovskites Modified with Ag and CeO(2)
  18. 329258
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    How is physical healthcare experienced by staff, service users, and carers in adult community mental health services in a south London mental health trust? A service evaluation
  19. 329259
    “…ChatGPT had a lower percentage of correct answers in some areas, such as pharmacology, social welfare, related law and regulations, endocrinology/metabolism, and dermatology, and a higher percentage of correct answers in the areas of nutrition, pathology, hematology, ophthalmology, otolaryngology, dentistry and dental surgery, and nursing integration and practice. CONCLUSIONS: ChatGPT only passed the 2019 Japanese National Nursing Examination during the most recent 5 years. …”
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    Performance of the Large Language Model ChatGPT on the National Nurse Examinations in Japan: Evaluation Study
  20. 329260
    “…A methodological quality assessment was performed, and the results were integrated into a thematic synthesis. The identification of the main opportunities and challenges was done by interpreting and aggregating the thematic synthesis results. …”
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    Facilitators of and Barriers to Accessing Hospital Medical Specialty Telemedicine Consultations During the COVID-19 Pandemic: Systematic Review
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