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330221por Hadique, Sarah, Badami, Varun, Forte, Michael, Kovacic, Nicole, Umer, Amna, Shigle, Amanda, Gardo, Jordan, Sangani, Rahul“…CONCLUSIONS: Implementation of comprehensive education, standardization of sedation prior to neuromuscular blocking agent initiation, integration of clinical variables in determining paralysis achievement, and proper use of peripheral nerve stimulation served as optimal strategies for the titration and monitoring of neuromuscular blocking agent in acute respiratory distress syndrome. …”
Publicado 2021
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330222“…In all, 20 reports described central statistical monitoring methods (of which 7 focussed on detection of fraud or misconduct) and 9 described triggered monitoring methods; 21 reports included some assessment of their methods’ effectiveness, typically exploring the methods’ characteristics using real trial data without known integrity issues. Of the 21 with some effectiveness assessment, most contained limited information about whether or not concerns identified through central monitoring constituted meaningful problems. …”
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330223
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330224“…So too is the need to better integrate LTSS with the health, social care, and public health systems. …”
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330225
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330226por Zablocki, Olivier, Michelsen, Michelle, Burris, Marie, Solonenko, Natalie, Warwick-Dugdale, Joanna, Ghosh, Romik, Pett-Ridge, Jennifer, Sullivan, Matthew B., Temperton, Ben“…Here we introduce VirION2, an integrated short- and long-read metagenomic wet-lab and informatics pipeline that updates our previous method (VirION) to further enhance the utility of long-read viral metagenomics. …”
Publicado 2021
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330227por Ioannou, George N., Green, Pamela, Fan, Vincent S., Dominitz, Jason A., O’Hare, Ann M., Backus, Lisa I., Locke, Emily, Eastment, McKenna C., Osborne, Thomas F., Ioannou, Nikolas G., Berry, Kristin“…VA EHR data streams were imported on a data integration platform to demonstrate that the model could be executed in real-time to produce dashboards with risk scores for all current VA enrollees. …”
Publicado 2021
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330228“…RESULTS: Over the 100 ns molecular dynamics simulations of 3CL-PRO’s crystal structures, 6LZE, 6M0K, and 6YB7, showed overall integrity with mean Cα root-mean-square deviation (RMSD) of 1.96 (±0.35) Å, 1.98 (±0.21) Å, and 1.94 (±0.25) Å, respectively. …”
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330229“…However, the cause and the underlying molecular events of CagA induction remain unclear. Here, we applied integrated bioinformatics to identify the key genes involved in the process of CagA-induced gastric epithelial cell inflammation and can ceration to comprehend the potential molecular mechanisms involved. …”
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330230por Luoto, Jill E, Garcia, Italo Lopez, Aboud, Frances E, Singla, Daisy R, Fernald, Lia C H, Pitchik, Helen O, Saya, Uzaib Y, Otieno, Ronald, Alu, Edith“…We aimed to test the effectiveness of two group-based delivery models for an integrated ECD responsive stimulation and nutrition education intervention using Kenya’s network of community health volunteers. …”
Publicado 2021
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330231“…EHRs are not simple computer applications; they should be considered as a highly integrated set of systems. Technology acceptance theories can be used to better understand users’ intentions to use EHRs. …”
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330232por Vita, Antonio, Barlati, Stefano, Ceraso, Anna, Nibbio, Gabriele, Ariu, Cassandra, Deste, Giacomo, Wykes, Til“…An active and trained therapist (cognition: χ(2)(1), 4.14; P = .04; functioning: χ(2)(1), 4.26; P = .04), structured development of cognitive strategies (cognition: χ(2)(1), 9.34; P = .002; functioning: χ(2)(1), 8.12; P = .004), and integration with psychosocial rehabilitation (cognition: χ(2)(1), 5.66; functioning: χ(2)(1), 12.08) were crucial ingredients of efficacy. …”
Publicado 2021
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330233Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse modelpor Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Van Helleputte, Lawrence, Schneidereit, Dominik, Haug, Michael, Reischl, Barbara, Friedrich, Oliver, Van Den Bosch, Ludo, Van den Berghe, Greet, Langouche, Lies“…Septic myofibres suffered from increased rupturing in a passive stretching protocol (25% more than control myofibres; P = 0.04), which was associated with impaired myofibre active force generation (P = 0.04), linking altered myofibre integrity to function. Sepsis also caused a reduction in muscle titin gene expression (P = 0.04) and myosin and actin protein content (P = 0.05), but not the myosin‐to‐actin ratio (P = 0.7). …”
Publicado 2021
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330234por Shiferaw, Kirubel Biruk, Mengiste, Shegaw Anagaw, Gullslett, Monika Knudsen, Zeleke, Atinkut Alamirrew, Tilahun, Binyam, Tebeje, Tsion, Wondimu, Robel, Desalegn, Surafel, Mehari, Eden Abetu“…In addition, mHealth approach was the most preferred modality of telemedicine and this opens an opportunity to integrate telemedicine systems in the health system during and post pandemic health services in low-income countries.…”
Publicado 2021
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330235por Johansen, Øystein H, Abdissa, Alemseged, Zangenberg, Mike, Mekonnen, Zeleke, Eshetu, Beza, Bjørang, Ola, Alemu, Yonas, Sharew, Bizuwarek, Langeland, Nina, Robertson, Lucy J, Hanevik, Kurt“…INTERPRETATION: LED-AP has high sensitivity and specificity for cryptosporidiosis and should be considered as a dual-use technology that can be easily integrated with existing laboratory infrastructures in low-resource settings. …”
Publicado 2021
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330236por Chavarria, Enmanuel A., Christy, Shannon M., Simmons, Vani N., Vadaparampil, Susan T., Gwede, Clement K., Meade, Cathy D.“…As a result, the materials were improved by using clearer, more salient language to enhance comprehension and cultural acceptability, by integrating design elements such as prompts, headers, and stylistic edits to reduce text density, incorporating preferred colors and graphics to improve aesthetic appeal, and including actionable terms and words to bolster motivation and self-efficacy. …”
Publicado 2021
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330237“…The limitations of an evidence-based approach require better integration of decision support tools to guide policymakers with digital mental health implementation. …”
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330238“…BACKGROUND: The use of digital health technologies was an integral part to China's early response to coronavirus disease 2019 (COVID-19). …”
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330239“…Then, we conducted meta-analyses by pooling the eQTL and sQTL results of CMC and GTEx using the inverse variance-weighted model. Afterward, we integrated QTL meta-analysis results (Q < 0.05) with the Glioma International Case Control Study (GICC) GWAS meta-analysis (case:12,496, control:18,190), using a summary statistics-based mendelian randomization (SMR) method. …”
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330240“…The hypothalamus controls food intake and metabolism by integrating nutrient and hormonal signals from peripheral tissues. …”
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