“…Kaiser Permanente Northern California is an integrated health care system with a community-based population of more than 4.4 million members. …”
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“…It is better to create awareness for the community and consider integrating religious and social interventions into medical interventions.…”
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“…CONCLUSIONS AND RELEVANCE: In this survey study, the perceived stressors associated with work-life integration were higher in women than men, were highest in women with children, and have been exacerbated by the COVID-19 pandemic. …”
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“…Due to its functional robustness and physiological relevance (3D culture, cells expose to fluid flow and co‐culture of different cell types), the liver MPS can, in a reproducible manner: (i) detect inflammatory‐induced drug toxicity, as demonstrated with trovafloxacin, (ii) detect the toxicity of other drugs, such as troglitazone, tamoxifen, and digoxin, with different effects than those detected in spheroids and sandwich cultures, (iii) enable studies of hepatic function that rely on prolonged cellular activity, and (iv) detect phase II metabolites and drug accumulation to potentially support the interpretation of clinical data. The integration of MPSs in drug development will be facilitated by careful evaluation of performance and reproducibility as performed in this study.…”
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“…Our results along with prior studies indicate that the integration of exosome release inhibitors into the common PLD-containing chemotherapy regimens could significantly lower the required concentrations of the drug and consequently reduce its associated side effects. …”
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“…This issue deserves considerable attention by health care system leaders in order to optimally integrate hospitals and primary care.…”
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“…INTRODUCTION: South Africa (SA) has the highest number of people living with HIV (PLWH) globally, and a significant burden of alcohol and other drug use (AOD). Although integrating AOD treatment into HIV care may improve antiretroviral therapy (ART) adherence, this is not typically routine practice in SA or other low‐resource settings. …”
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“…CONCLUSIONS: Persistent depressive symptoms were common among African AGYW seeking PrEP. Integration of depressive symptom screening and treatment into PrEP programmes may improve PrEP effectiveness among African women.…”
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“…We used linear mixed-effects models to investigate how circadian rhythms changed longitudinally and how the change integrated to Alzheimer’s progression. FINDINGS: Participants had a median age of 81·8 (IQR 76·3–85·7) years. …”
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“…Additionally, there was a positive correlation between distal KF injuries and lateral tibial plateau BME (P = .035), but no associations were found with the lateral femoral notch sign or other patterns of BME, including pivot-shift BME. CONCLUSION: KF integrity and injury can be reliably detected on routine knee MRI scans. …”
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“…In the training set, clinical features and Doppler hemodynamic parameters before MTX therapy were analyzed using logistic regression to identify independent predictors of MTX resistance, which were integrated into the model. The predictive performance of the model was evaluated by leave‐one‐out cross‐validation in the training dataset and internal validation in an independent‐sample test dataset. …”
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“…To elucidate how loss of IGF-1R function impacts aggressive breast cancers, we have integrated the use of human patient data with mouse models where IGF-1R has been deleted or dysregulated. …”
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“…The prediction accuracy for anthesis date and plant height across WW and WS environments obtained using 1-year data and integrating 10, 30, 50, 70, and 90% of the TST set to TRN set was much higher than those trained in individual years. …”
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“…Using an autoregressive integrated moving average algorithm, we forecasted the weekly relative search volume (RSV) for GT search topics and terms related to colon cancer that would have been expected had his death not occurred and compared it with observed RSV data. …”
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“…CONCLUSION: This study suggests that high-risk HPV 16/18 infection, chronic lower abdominal pain with vaginal bleeding, and decreased upper and lower trunk body mass, are associated with higher risk of precancerous cervical lesions. Integrating targeted cervical cancer screening in routine reproductive health-care services may reduce the risk of developing cervical cancer.…”
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“…BACKGROUND: Longitudinal changes in white matter (WM) integrity have been reported following cumulative exposure to sub-concussive head impacts (SCI) incurred during sports. …”
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