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  1. 330821
    “…We found that ePROMs are an integrative and facilitative communication tool, highlighting their importance in the relationship between palliative care and medical oncology. ePROMs help assess patient symptoms and functionality more accurately and facilitate clinical decision-making. …”
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    Improving the Understanding and Managing of the Quality of Life of Patients With Lung Cancer With Electronic Patient-Reported Outcome Measures: Scoping Review
  2. 330822
    “…Throughout the 4 days of storage, sperm motility, viability and acrosome integrity in the ANTIBIOTIC group were higher than those in the NO-ANTIBIOTIC group (p < 0.05), while the total bacterial count was lower (1.9 ± 0.1 versus 3.9 ± 0.1 log(10), respectively; p < 0.001). …”
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    Bacteriospermia and its antimicrobial resistance in relation to boar sperm quality during short-term storage with or without antibiotics in a tropical environment
  3. 330823
    “…CONCLUSION: We performed a novel integrated analysis of the potential role of CTD in HCC treatment. …”
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    Cantharidin suppresses hepatocellular carcinoma development by regulating EZH2/H3K27me3-dependent cell cycle progression and antitumour immune response
  4. 330824
    “…METHODS: Randomized patients received DMF 240 mg twice daily or placebo (PBO; years 0–2 DEFINE/CONFIRM), then DMF (years 3–10; continuous DMF/DMF or PBO/DMF; ENDORSE); maximum follow-up (combined studies) was 13 years. This integrated post hoc analysis evaluated safety and efficacy of DMF in a subgroup of young adults aged 18–29 years. …”
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    Efficacy of Dimethyl Fumarate in Young Adults with Relapsing-Remitting Multiple Sclerosis: Analysis of the DEFINE, CONFIRM, and ENDORSE Studies
  5. 330825
    “…Human–computer conversation data were well integrated into the diagnostic process, and the system was well accepted by patients. …”
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    Verification of a clinical decision support system for the diagnosis of headache disorders based on patient–computer interactions: a multi-center study
  6. 330826
    “…BACKGROUND: TeleCheck-AF is a digital care pathway, which consists of a structured teleconsultation ("Tele") preceded by an app-based on-demand heart rate and rhythm monitoring infrastructure ("Check") and the consecutive integration of the app-derived findings in a comprehensive atrial fibrillation (AF) management. …”
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    Changes in healthcare utilisation and declarable care products during the implementation of a remote atrial fibrillation management pathway: The TeleCheck-AF project
  7. 330827
    “…PURPOSE: To describe the implementation of an integrated screening and management pathway for COPD in patients with diagnosed AF, into the existing pre-ablation work-up embedded in an AF outpatient clinic infrastructure. …”
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    Implementation of a screening and management pathway for chronic obstructive pulmonary disease in patients with atrial fibrillation
  8. 330828
    “…Additionally, the AIP provided incremental predictive capacity over established risk factors for CA, as shown by an improvement in the net reclassification index (NRI) and integrated discrimination index (IDI) (all P < 0.05). …”
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    The atherogenic index of plasma and carotid atherosclerosis in a community population: a population-based cohort study in China
  9. 330829
    “…CONCLUSIONS AND RELEVANCE: To date, this is the first multisite randomized clinical trial to evaluate perioperative palliative care and the earliest integration of palliative care into cancer care. Unlike in medical oncology practice, the data from this trial do not suggest palliative care–associated improvements in patient-reported outcomes among patients pursuing curative-intent surgeries for upper GI cancers. …”
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    Effect of Perioperative Palliative Care on Health-Related Quality of Life Among Patients Undergoing Surgery for Cancer: A Randomized Clinical Trial
  10. 330830
    “…Finally, the CIBERSORT algorithm was used to explore immune cell infiltration in CAVD. RESULTS: The integrated CAVD dataset identified 124 CAVD key genes by intersecting differential expression and WGCNA analyses. …”
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    Screening of immune-related secretory proteins linking chronic kidney disease with calcific aortic valve disease based on comprehensive bioinformatics analysis and machine learning
  11. 330831
    “…Other items are specific to the environment of obstetrics. One example is integration of spinal anesthesia into the obstetric context. …”
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    Entwicklung eines Kompetenzkatalogs für Ärzt:Innen in Weiterbildung zur Curriculumerstellung für die Kreißsaaleinarbeitung
  12. 330832
    “…The primary outcomes were changes in the scores of five tests in the THINC-integrated tool (THINC-it) at week 2 (W2) and week 4 (W4). …”
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    Targeted visual cortex stimulation (TVCS): a novel neuro-navigated repetitive transcranial magnetic stimulation mode for improving cognitive function in bipolar disorder
  13. 330833
    “…Then, we harvested a combination of SNPs as an integrated proxy for the five socioeconomic traits to perform a MVMR analysis based on IVW MVMR model. …”
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    Evaluation for causal effects of socioeconomic traits on risk of female genital prolapse (FGP): a multivariable Mendelian randomization analysis
  14. 330834
    “…DESIGN: Retrospective cohort study. SETTING: Four integrated health systems and two national health insurers in the US Food and Drug Administration's Sentinel System. …”
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    Risk of admission to hospital with arterial or venous thromboembolism among patients diagnosed in the ambulatory setting with covid-19 compared with influenza: retrospective cohort study
  15. 330835
    “…Background: Cystic fibrosis (CF) is caused by a wide spectrum of mutations in the CF transmembrane conductance regulator (CFTR) gene, with some leading to non-classical clinical presentations. We present an integrated in vivo, in silico and in vitro investigation of an individual with CF carrying the rare Q1291H-CFTR allele and the common F508del allele. …”
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    Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient
  16. 330836
    “…In addition, we found that the integration of clinical prognostic variables and deep features of images can improve the stratification of patient prognosis. …”
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    Prediction of clinicopathological features, multi-omics events and prognosis based on digital pathology and deep learning in HR(+)/HER2(−) breast cancer
  17. 330837
    “…CONCLUSION: SXT reverses CHF-induced cardiac dysfunction and maintains the integrity of myocardial structure by regulating energy metabolism. …”
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    Shengxian decoction protects against chronic heart failure in a rat model via energy regulation mechanisms
  18. 330838
    “…The construct of intrinsic capacity (IC) in the context of integrated care for older adults emphasizes functional assessment from a holistic perspective. …”
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    Associations between intrinsic capacity, functional difficulty, and fall outcomes among older adults in India
  19. 330839
    “…Variation in adoption at the mesolevel was related to stable and motivated leadership (particularly at the facility level), poor integration into routine processes, and buy-in from senior district managers who were affected by competing priorities. …”
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    Intervention in Mothers and Newborns to Reduce Maternal and Perinatal Mortality in 3 Provinces in South Africa Using a Quality Improvement Approach: Protocol for a Mixed Method Type 2 Hybrid Evaluation
  20. 330840
    “…OBJECTIVES: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS) and respiratory failure under US FDA Emergency Use Authorization. …”
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    Extracorporeal hemoadsorption in critically ill COVID-19 patients on VV ECMO: the CytoSorb therapy in COVID-19 (CTC) registry
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