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331001por Croudace, Tim, Brazier, John, Gutacker, Nils, Street, Andrew, Robotham, Dan, Waterman, Samantha, Rose, Diana, Satkunanathan, Safarina, Wykes, Til, Nasr, Nasrin, Enderby, Pamela, Carlton, Jill, Rowen, Donna, Elliott, Jackie, Brazier, John, Stevens, Katherine, Basarir, Hasan, Labeit, Alex, Murphy, Mairead, Hollinghurst, Sandra, Salisbury, Chris, Marley, Dominic, Wilson, James, Barrat, Amy, Roy, Bibhas, Rombach, Ines, Burke, Órlaith, Jenkinson, Crispin, Gray, Alastair, Rivero-Arias, Oliver, Porter, Ian, Gangannagaripalli, Jaheeda, Bramwell, Charlotte, Valderas, Jose M., Holch, Patricia, Davidson, Susan, Routledge, Jacki, Henry, Ann, Franks, Kevin, Gilbert, Alex, Absolom, Kate, Velikova, Galina, Porter, Ian, Valderas, Jose M., Boehnke, Jan R., Trigg, Andrew, Howells, Ruth, Singh, Jeshika, Pokhrel, Subhash, Longworth, Louise, Potter, Caroline, Hunter, Cheryl, Kelly, Laura, Gibbons, Elizabeth, Forder, Julian, Coulter, Angela, Fitzpatrick, Ray, Peters, Michele“…—Using PROMs to inform patients about the likely benefit of surgery Nils Gutacker, Andrew Street O2 Identifying Patient Reported Outcome Measures for an electronic Personal Health Record Dan Robotham, Samantha Waterman, Diana Rose, Safarina Satkunanathan, Til Wykes O3 Examining the change process over time qualitatively: transformative learning and response shift Nasrin Nasr, Pamela Enderby O4 Developing a PROM to evaluate self-management in diabetes (HASMID): giving patients a voice Jill Carlton, Donna Rowen, Jackie Elliott, John Brazier, Katherine Stevens, Hasan Basarir, Alex Labeit O5 Development of the Primary Care Outcomes Questionnaire (PCOQ) Mairead Murphy, Sandra Hollinghurst, Chris Salisbury O6 Developing the PKEX score- a multimodal assessment tool for patients with shoulder problems Dominic Marley, James Wilson, Amy Barrat, Bibhas Roy O7 Applying multiple imputation to multi-item patient reported outcome measures: advantages and disadvantages of imputing at the item, sub-scale or score level Ines Rombach, Órlaith Burke, Crispin Jenkinson, Alastair Gray, Oliver Rivero-Arias O8 Integrating Patient Reported Outcome Measures (PROMs) into routine primary care for patients with multimorbidity: a feasibility study Ian Porter, Jaheeda Gangannagaripalli, Charlotte Bramwell, Jose M. …”
Publicado 2016
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331002por Ferreira, João Pedro, Girerd, Nicolas, Pellicori, Pierpaolo, Duarte, Kevin, Girerd, Sophie, Pfeffer, Marc A., McMurray, John J. V., Pitt, Bertram, Dickstein, Kenneth, Jacobs, Lotte, Staessen, Jan A., Butler, Javed, Latini, Roberto, Masson, Serge, Mebazaa, Alexandre, Rocca, Hans Peter Brunner-La, Delles, Christian, Heymans, Stephane, Sattar, Naveed, Jukema, J. Wouter, Cleland, John G., Zannad, Faiez, Rossignol, Patrick“…The discriminative improvement driven by the CG-BSA formula was superior to that of MDRD4 and CKD-EPI, but remained low overall (increase in C-index ranging from 0.5 to 2%) while not statistically significant in population-based cohorts. The integrated discrimination improvement and net reclassification improvement were higher (P < 0.05) for the CG-BSA formula compared to MDRD4 and CKD-EPI in CV risk, HF and post-MI cohorts, but not in population-based cohorts. …”
Publicado 2016
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331003por Deribew, Amare, Tessema, Gizachew Assefa, Deribe, Kebede, Melaku, Yohannes Adama, Lakew, Yihunie, Amare, Azmeraw T., Abera, Semaw F., Mohammed, Mesoud, Hiruye, Abiy, Teklay, Efrem, Misganaw, Awoke, Kassebaum, Nicholas“…These findings call for better-integrated newborn and child survival interventions focusing on the main risk factors.…”
Publicado 2016
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331004por Closson, Kalysha, Dietrich, Janan Janine, Nkala, Busi, Musuku, Addy, Cui, Zishan, Chia, Jason, Gray, Glenda, Lachowsky, Nathan J., Hogg, Robert S., Miller, Cari L., Kaida, Angela“…HIV prevention interventions targeting adolescents must address the syndemics of trauma and HIV through the scale-up of gender-transformative, youth-centred, trauma-informed integrated HIV and mental health services. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12889-016-3832-0) contains supplementary material, which is available to authorized users.…”
Publicado 2016
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331005por Shi, Jianxin, Hua, Xing, Zhu, Bin, Ravichandran, Sarangan, Wang, Mingyi, Nguyen, Cu, Brodie, Seth A., Palleschi, Alessandro, Alloisio, Marco, Pariscenti, Gianluca, Jones, Kristine, Zhou, Weiyin, Bouk, Aaron J., Boland, Joseph, Hicks, Belynda, Risch, Adam, Bennett, Hunter, Luke, Brian T., Song, Lei, Duan, Jubao, Liu, Pengyuan, Kohno, Takashi, Chen, Qingrong, Meerzaman, Daoud, Marconett, Crystal, Laird-Offringa, Ite, Mills, Ian, Caporaso, Neil E., Gail, Mitchell H., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Chanock, Stephen J., Landi, Maria Teresa“…METHODS AND FINDINGS: We performed an integrative genomic analysis, incorporating whole exome sequencing (WES), determination of DNA copy number and DNA methylation, and transcriptome sequencing for 101 LUAD samples from the Environment And Genetics in Lung cancer Etiology (EAGLE) study. …”
Publicado 2016
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331006por Balsalobre, Thiago Willian Almeida, da Silva Pereira, Guilherme, Margarido, Gabriel Rodrigues Alves, Gazaffi, Rodrigo, Barreto, Fernanda Zatti, Anoni, Carina Oliveira, Cardoso-Silva, Cláudio Benício, Costa, Estela Araújo, Mancini, Melina Cristina, Hoffmann, Hermann Paulo, de Souza, Anete Pereira, Garcia, Antonio Augusto Franco, Carneiro, Monalisa Sampaio“…The objectives of this study were to (i) establish a pipeline for identifying variants from genotyping-by-sequencing (GBS) data in sugarcane, (ii) construct an integrated genetic map with GBS-based markers plus target region amplification polymorphisms and microsatellites, (iii) detect QTLs related to yield component traits, and (iv) perform annotation of the sequences that originated the associated markers with mapped QTLs to search putative candidate genes. …”
Publicado 2017
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331007por Erismann, Séverine, Knoblauch, Astrid M., Diagbouga, Serge, Odermatt, Peter, Gerold, Jana, Shrestha, Akina, Tarnagda, Grissoum, Savadogo, Boubacar, Schindler, Christian, Utzinger, Jürg, Cissé, Guéladio“…The “Vegetables go to School: improving nutrition through agricultural diversification” (VgtS) project implements an integrated school garden programme in five countries, including Burkina Faso. …”
Publicado 2017
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331008por Ziganshin, Bulat A., Sadigh, Mitra, Yausheva, Liliya M., Ziganshina, Anna P., Pichugin, Arseniy A., Sozinov, Alexey S., Amirov, Nail Kh., Rastegar, Asghar, Ziganshin, Ayrat U., Sadigh, Majid“…Their responsibilities included familiarizing Russian colleagues with specific topics in clinical medicine, importing knowledge about the basics of teaching, clinical epidemiology and evidence based medicine, and creating, in consistency with the American model, a “Clinical Teaching Team Structure” that integrates patient care with clinical education. Furthermore, 44 of selected KSMU members, including 13 junior faculty (29.5%), 14 clinical PhD students (31.8%), 12 interns/residents (27.3%), and five medical students (11.4%), were trained at Yale/WCHN or one of their major affiliated community hospitals for a period of 1 to 12 months for a total of 844 participant-weeks of training. …”
Publicado 2017
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331009por Link, Jenny, Ramanujam, Ryan, Auer, Michael, Ryner, Malin, Hässler, Signe, Bachelet, Delphine, Mbogning, Cyprien, Warnke, Clemens, Buck, Dorothea, Hyldgaard Jensen, Poul Erik, Sievers, Claudia, Ingenhoven, Kathleen, Fissolo, Nicolas, Lindberg, Raija, Grummel, Verena, Donnellan, Naoimh, Comabella, Manuel, Montalban, Xavier, Kieseier, Bernd, Soelberg Sørensen, Per, Hartung, Hans-Peter, Derfuss, Tobias, Lawton, Andy, Sikkema, Dan, Pallardy, Marc, Hemmer, Bernhard, Deisenhammer, Florian, Broët, Philippe, Dönnes, Pierre, Davidson, Julie, Fogdell-Hahn, Anna“…Antibodies against biopharmaceuticals (anti-drug antibodies, ADA) have been a well-integrated part of the clinical care of multiple sclerosis (MS) in several European countries. …”
Publicado 2017
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331010por Lai, Yinglei, Zhang, Fanni, Nayak, Tapan K., Modarres, Reza, Lee, Norman H., McCaffrey, Timothy A.“…The related differential expression analysis and gene set enrichment analysis have been frequently conducted. Integrative analysis can be conducted when multiple data sets are available. …”
Publicado 2017
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331011por Hill, Katherine E., Kelly, Andrew D., Kuijjer, Marieke L., Barry, William, Rattani, Ahmed, Garbutt, Cassandra C., Kissick, Haydn, Janeway, Katherine, Perez-Atayde, Antonio, Goldsmith, Jeffrey, Gebhardt, Mark C., Arredouani, Mohamed S., Cote, Greg, Hornicek, Francis, Choy, Edwin, Duan, Zhenfeng, Quackenbush, John, Haibe-Kains, Benjamin, Spentzos, Dimitrios“…We assessed the clinical utility of this miRNA set and their association with methylation status. METHODS: We integrated coding and non-coding RNA data from three independent annotated clinical osteosarcoma cohorts (n = 65, n = 27, and n = 25) and miRNA and methylation data from one in vitro (19 cell lines) and one clinical (NCI Therapeutically Applicable Research to Generate Effective Treatments (TARGET) osteosarcoma dataset, n = 80) dataset. …”
Publicado 2017
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331012por Leal Neto, Onicio, Dimech, George Santiago, Libel, Marlo, de Souza, Wayner Vieira, Cesse, Eduarda, Smolinski, Mark, Oliveira, Wanderson, Albuquerque, Jones“…Compared to traditional epidemiological surveillance, advantages include lower costs of data acquisition, timeliness of information collected and shared, platform scalability, and capacity for integration between the population being served and public health services.…”
Publicado 2017
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331013por Gaertner, Jan, Siemens, Waldemar, Meerpohl, Joerg J, Antes, Gerd, Meffert, Cornelia, Xander, Carola, Stock, Stephanie, Mueller, Dirk, Schwarzer, Guido, Becker, Gerhild“…Results Of 3967 publications, 12 were included (10 randomised controlled trials with 2454 patients randomised, of whom 72% (n=1766) had cancer). In no trial was integration of specialist palliative care triggered according to patients’ needs as identified by screening. …”
Publicado 2017
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331014por Zhu, Lin, Müller, Günter C., Marshall, John M., Arheart, Kristopher L., Qualls, Whitney A., Hlaing, WayWay M., Schlein, Yosef, Traore, Sekou F., Doumbia, Seydou, Beier, John C.“…There are considerations of incorporating outdoor interventions into integrated vector management (IVM) to achieve malaria elimination; however, more information on the combination of tools for effective control is needed to determine their utilization. …”
Publicado 2017
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331015por Quiles, Justin M., Narasimhan, Madhusudhanan, Shanmugam, Gobinath, Milash, Brett, Hoidal, John R., Rajasekaran, Namakkal S.“…High throughput data were integrated using prediction algorithms, and these in silico analyses discovered potential recognition elements within 39 repressed mRNAs which matched the seed sequence for 4 upregulated miRNAs; miR-30b-5p, miR-208a-5p, miR-350-3p, and miR-582-5p. …”
Publicado 2017
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331016por Voruganti, Teja, Grunfeld, Eva, Jamieson, Trevor, Kurahashi, Allison M, Lokuge, Bhadra, Krzyzanowska, Monika K, Mamdani, Muhammad, Moineddin, Rahim, Husain, Amna“…OBJECTIVE: The objectives of this pilot study were to evaluate the feasibility of integrating a tool like Loop into current care practices and to capture preliminary measures of the effect of Loop on continuity of care, quality of care, symptom distress, and health care utilization. …”
Publicado 2017
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331017“…This tailored content will match HIV prevention messages and safer sex skills with YMSM’s outcome expectancies when meeting new partners and thereby help them consider how to integrate safer sex practices into different partner types. …”
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331018por Stokes, Jonathan, Kristensen, Søren Rud, Checkland, Kath, Cheraghi-Sohi, Sudeh, Bower, Peter“…Case management is a popular method of integrating care, seeking to accomplish this goal. However, the intervention has shown limited effectiveness. …”
Publicado 2017
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331019por Wang, Lingshu, Qing, Li, Liu, He, Liu, Na, Qiao, Jingting, Cui, Chen, He, Tianyi, Zhao, Ruxing, Liu, Fuqiang, Yan, Fei, Wang, Chuan, Liang, Kai, Guo, Xinghong, Shen, Ying H., Hou, Xinguo, Chen, Li“…The islets of Langerhans are highly vascularized miniorgans, and preserving the structural integrity and full function of the microvascular endothelium is vital for protecting the islets from the infiltration of immune cells and secondary inflammatory attack. …”
Publicado 2017
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331020por Tinschert, Peter, Jakob, Robert, Barata, Filipe, Kramer, Jan-Niklas, Kowatsch, Tobias“…Therefore, app reviews should be considered as a decision support tool before deciding which app to integrate into a patient’s asthma self-management. …”
Publicado 2017
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