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331021por de Mulder, Miguel, SenGupta, Devi, Deeks, Steven G., Martin, Jeffrey N., Pilcher, Christopher D., Hecht, Frederick M., Sacha, Jonah B., Nixon, Douglas F., Michaud, Henri-Alexandre“…BACKGROUND: Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome and while the majority are transcriptionally silent, the most recently integrated HERV, HERV-K (HML-2), remains active. During HIV infection, HERV-K (HML-2) specific mRNA transcripts and viral proteins can be detected. …”
Publicado 2017
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331022“…Thematic analysis of qualitative interviews with 14 participants found that Check Up GP created scope to address unmet health needs and increased sense of preparedness, with use moderated by honesty, motivation, app content and functionality, and app administration. CONCLUSIONS: Integrating a health and lifestyle-screening app into face-to-face care can enrich young people’s experience of seeing their GP, create scope to identify and address unmet health needs, and increase patient-centered care. …”
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331023por Cai, Ran A, Beste, Dominik, Chaplin, Hema, Varakliotis, Socrates, Suffield, Linda, Josephs, Francesca, Sen, Debajit, Wedderburn, Lucy R, Ioannou, Yiannakis, Hailes, Stephen, Eleftheriou, Despina“…These included (4) adapting a reward system to motivate end users for using the app; (5) design of the app interface; and (6) clinical practice integration. The usability testing during phase III demonstrated high rates of overall satisfaction and further affirmed the content validity of the app. …”
Publicado 2017
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331024por Yeh, Pei-Han, Hung, Shih-Kai, Lee, Moon-Sing, Chiou, Wen-Yen, Lai, Chun-Liang, Tsai, Wei-Ta, Hsieh, Hui-Ling, Shih, Yi-Ting, Chen, Liang-Cheng, Huang, Li-Wen, Lin, Yi-An, Lin, Po-Hao, Lin, Yung-Hsiang, Liu, Dai-Wei, Hsu, Feng-Chun, Tsai, Shiang-Jiun, Liu, Jia-Chi, Chung, En-Seu, Lin, Hon-Yi“…OBJECTS: In our web-based integrated information platform, we constructed a ping-pong-type e-communication function to transfer specific notations among multidisciplinary RT staffs. …”
Publicado 2016
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331025por Brinker, Titus Josef, Brieske, Christian Martin, Schaefer, Christoph Matthias, Buslaff, Fabian, Gatzka, Martina, Petri, Maximilian Philip, Sondermann, Wiebke, Schadendorf, Dirk, Stoffels, Ingo, Klode, Joachim“…CONCLUSIONS: We present a novel way of integrating photoaging in school-based melanoma prevention that affects the students’ peer group, considers the predictors of UV exposure in accordance with the theory of planned behavior, and is particularly effective in changing behavioral predictors in fair-skinned adolescents (Fitzpatrick skin types 1-2). …”
Publicado 2017
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331026por Ball, Sarah, Naleway, Allison, Kwong, Jeffrey C, Reagan, Annette K, Simmonds, Kimberley, Feldman, Becca, Azziz-Baumgartner, Eduardo, Wyant, Brandy, Klein, Nicola P, Fell, Deshayne, Effler, Paul, Booth, Stephanie, Katz, Mark, Dawood, Fatimah S, Shifflett, Patricia, Jackson, Michael L, Buchan, Sarah, Levy, Avram, Drews, Steven, Garg, Shikha, Irving, Stephanie, Russell, Margaret L, Lewis, Edwin, Crane, Bradley, Modaressi, Sharareh, Slaughter, Matthew, Goddard, Kristin, Thompson, Mark G“…We selected sites that could identify the population of women known to be pregnant during flu seasons and integrate their hospitalization data, clinical laboratory testing, and vaccination records. …”
Publicado 2017
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331027por Akin, Sakir, dos Reis Miranda, Dinis, Caliskan, Kadir, Soliman, Osama I., Guven, Goksel, Struijs, Ard, van Thiel, Robert J., Jewbali, Lucia S., Lima, Alexandre, Gommers, Diederik, Zijlstra, Felix, Ince, Can“…TVDss(F50) (21.9 vs 12.9 mm/mm(2), p = 0.001), PVDss(F50) (19.7 vs 12.4 mm/mm(2), p = 0.01) and aortic velocity–time integral (VTI) at 50% flow reduction (VTI(F50)) were higher in patients successfully weaned vs not successfully weaned. …”
Publicado 2017
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331028por Eze, Ikenna C, Esse, Clémence, Bassa, Fidèle K, Koné, Siaka, Acka, Felix, Yao, Loukou, Imboden, Medea, Jaeger, Fabienne N, Schindler, Christian, Dosso, Mireille, Laubhouet-Koffi, Véronique, Kouassi, Dinard, N’Goran, Eliézer K, Utzinger, Jürg, Bonfoh, Bassirou, Probst-Hensch, Nicole“…CONCLUSIONS: The collaboration between research institutions, public health organizations, health care providers, and staff from the Taabo HDSS in this study assures that the synthesized evidence will feed into health policy towards integrated infectious disease-NCD management. The preparation of health systems for the dual burden of disease is pressing in low- and middle-income countries. …”
Publicado 2017
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331029por Wang, Guan, Durussel, Jérôme, Shurlock, Jonathan, Mooses, Martin, Fuku, Noriyuki, Bruinvels, Georgie, Pedlar, Charles, Burden, Richard, Murray, Andrew, Yee, Brendan, Keenan, Anne, McClure, John D., Sottas, Pierre-Edouard, Pitsiladis, Yannis P.“…Further studies are required to confirm, and if necessary, integrate the confounding effects of altitude training on blood doping. …”
Publicado 2017
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331030por Garner, Bryan R., Zehner, Mark, Roosa, Mathew R., Martino, Steve, Gotham, Heather J., Ball, Elizabeth L., Stilen, Patricia, Speck, Kathryn, Vandersloot, Denna, Rieckmann, Traci R., Chaple, Michael, Martin, Erika G., Kaiser, David, Ford, James H.“…BACKGROUND: Improving the extent to which evidence-based practices (EBPs)—treatments that have been empirically shown to be efficacious or effective—are integrated within routine practice is a well-documented challenge across numerous areas of health. …”
Publicado 2017
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331031por Igwe, David Okeh, Afiukwa, Celestine Azubike, Ubi, Benjamin Ewa, Ogbu, Kenneth Idika, Ojuederie, Omena Bernard, Ude, George Nkem“…Our study demonstrated that SCoT markers were more efficient than ISSR for genetic diversity studies in V. unguiculata and can be integrated in the exploration of their genetic diversity for improvement and germplasm utilization. …”
Publicado 2017
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331032por Garvelink, Mirjam Marjolein, Jones, C Allyson, Archambault, Patrick M, Roy, Noémie, Blair, Louisa, Légaré, France“…In phase II, after 4 days in a studio with 15 bilingual actors, 30 videos were made of various experts (eg, family doctor, home care nurse, and social worker) presenting options and guidance for the decision-making process. These were integrated into an interactive website, which included a comments tool for visitors to add information. …”
Publicado 2017
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331033por Puydinger dos Santos, Marcos Vinicius, Szkudlarek, Aleksandra, Rydosz, Artur, Guerra-Nuñez, Carlos, Béron, Fanny, Pirota, Kleber Roberto, Moshkalev, Stanislav, Diniz, José Alexandre, Utke, Ivo“…Non-noble metals, such as Cu and Co, as well as noble metals, such as Au, can be used in a number modern technological applications, which include advanced scanning-probe systems, magnetic memory and storage, ferroelectric tunnel junction memristors, metal interconnects for high performance integrated circuits in microelectronics and nano-optics applications, especially in the areas of plasmonics and metamaterials. …”
Publicado 2018
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331034por de Sá Machado Araújo, Graziela, da Silva Francisco Junior, Ronaldo, dos Santos Ferreira, Cristina, Mozer Rodrigues, Pedro Thyago, Terra Machado, Douglas, Louvain de Souza, Thais, Teixeira de Souza, Jozimara, Figueiredo Osorio da Silva, Cleiton, Alves da Silva, Antônio Francisco, Andrade, Claudia Caixeta Franco, da Silva, Alan Tardin, Ramos, Victor, Garcia, Ana Beatriz, Machado, Filipe Brum, Medina-Acosta, Enrique“…Here, we used a comparative computational data mining approach to identify 125 novel constitutive candidate iDMRs that integrate the maximal number of allele-specific methylation region records overlapping CGIs in human methylomes. …”
Publicado 2018
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331035por Ding, Chenyue, Zou, Qinyan, Wang, Fuxin, Wu, Huihua, Chen, Rulei, Lv, Jinghuan, Ling, Mingfa, Sun, Jian, Wang, Wei, Li, Hong, Huang, Boxian“…CONCLUSIONS: These findings provide insight into the notion that hAMSCs play an integral role in resistance to NOA. Furthermore, our present study demonstrates that a growth factor combination derived from hAMSCs plays a central role in inhibiting ovarian aging. …”
Publicado 2018
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331036por Kadiyala, Suneetha, Prost, Audrey, Harris-Fry, Helen, O’Hearn, Meghan, Pradhan, Ronali, Pradhan, Shibananth, Mishra, Naba Kishore, Rath, Suchitra, Nair, Nirmala, Rath, Shibanand, Tripathy, Prasantha, Krishnan, Sneha, Koniz-Booher, Peggy, Danton, Heather, Elbourne, Diana, Sturgess, Joanna, Beaumont, Emma, Haghparast-Bidgoli, Hassan, Skordis-Worrall, Jolene, Mohanty, Satyanarayan, Upadhay, Avinash, Allen, Elizabeth“…DISCUSSION: This trial will contribute evidence on the impacts of NSA extension through participatory, low-cost, video-based approaches on maternal and child nutrition and on whether integration with nutrition-specific goals and enhanced participatory approaches can increase these impacts. …”
Publicado 2018
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331037por Fairall, Lara, Petersen, Inge, Zani, Babalwa, Folb, Naomi, Georgeu-Pepper, Daniella, Selohilwe, One, Petrus, Ruwayda, Mntambo, Ntokozo, Bhana, Arvin, Lombard, Carl, Bachmann, Max, Lund, Crick, Hanass-Hancock, Jill, Chisholm, Daniel, McCrone, Paul, Carmona, Sergio, Gaziano, Thomas, Levitt, Naomi, Kathree, Tasneem, Thornicroft, Graham“…Control group clinics are implementing the South African Department of Health’s Integrated Clinical Services Management model, which aims to reduce fragmentation of care in the context of rising multimorbidity, and which includes training in the Primary Care 101 (PC101) guide covering communicable diseases, NCDs, women’s health and mental disorders. …”
Publicado 2018
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331038por Tokish, John M., Thigpen, Charles A., Kissenberth, Michael J., Tolan, Stefan John, Lonergan, Keith T., Hawkins, Richard J., Kwapisz, Adam, Shanley, Ellen“…The purpose of this study, therefore, was to evaluate patients managed nonoperatively for shoulder instability, and to identify factors that led to failure, defined as an inability to return to sport with no subsequent missed time due to shoulder issues. We sought to integrate these factors into a scoring system that would predict the success or failure of nonoperative management in the treatment of shoulder instability in the adolescent athlete. …”
Publicado 2018
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331039por Dufresne, Sébastien S., Boulanger-Piette, Antoine, Bossé, Sabrina, Argaw, Anteneh, Hamoudi, Dounia, Marcadet, Laetitia, Gamu, Daniel, Fajardo, Val A., Yagita, Hideo, Penninger, Josef M., Russell Tupling, A., Frenette, Jérôme“…These findings demonstrate the superiority of full-length OPG-Fc treatment relative to truncated OPG-Fc, anti-RANKL, anti-TRAIL or muscle RANK deletion in improving dystrophic muscle function, integrity and protection against eccentric contractions. …”
Publicado 2018
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331040por Marchesi, Francesco, Regazzo, Giulia, Palombi, Francesca, Terrenato, Irene, Sacconi, Andrea, Spagnuolo, Manuela, Donzelli, Sara, Marino, Mirella, Ercolani, Cristiana, Di Benedetto, Anna, Blandino, Giovanni, Ciliberto, Gennaro, Mengarelli, Andrea, Rizzo, Maria Giulia“…High expression level of serum miR-22 in DLBCL at diagnosis (n = 36) is associated with a worse PFS and is independent of the currently used clinical prognostic index. Integrative and pathways analysis of miR-22 identified target genes involved in different important pathways such as p53 signaling. …”
Publicado 2018
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