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331241por Gwadz, Marya, Cleland, Charles M., Freeman, Robert, Wilton, Leo, Collins, Linda M., L. Hawkins, Robert, Ritchie, Amanda S., Leonard, Noelle R., Jonas, Danielle F., Korman, Alexis, Cluesman, Sabrina, He, Ning, Sherpa, Dawa“…Qualitative data were analyzed using a directed content analysis approach and results were integrated. RESULTS: Participants were diagnosed 18.2 years ago on average (SD = 8.6), started ART a median five times (Q1 = 3, Q3 = 10), and the median longest duration of sustained ART was 18 months (Q1 = 6, Q3 = 36). …”
Publicado 2021
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331242por Queiroz, Artur Acelino Francisco Luz Nunes, Mendes, Isabel Amélia Costa, de Godoy, Simone, Velez Lapão, Luís, Dias, Sónia“…For the systematic review, we followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines adapted for an integrative review in the databases of PubMed, Web of Knowledge, Scopus, Cochrane, Embase, Science Direct, Eric, Treasure, and CINAHL. …”
Publicado 2021
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331243por Milton, Alyssa Clare, Hambleton, Ashlea, Dowling, Mitchell, Roberts, Anna Elizabeth, Davenport, Tracey, Hickie, Ian“…The workshops highlighted seven overarching qualitative themes: identified barriers to care within the current system; need for people to be able to access the right care anywhere, anytime; recommendations for the technological solution (ie, InnoWell Platform features and functionality); need for communication, coordination, and integration of a technological solution embedded in Butterfly’s National Helpline; need to consider engagement and tone within the technological solution; identified challenges and areas to consider when implementing a technological solution in the Helpline; and potential outcomes of the technological solution embedded in the Helpline relating to system and service reform. …”
Publicado 2021
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331244por Clift, Ashley K, Le Lannou, Erwann, Tighe, Christian P, Shah, Sachin S, Beatty, Matthew, Hyvärinen, Arsi, Lane, Stephen J, Strauss, Tamir, Dunn, Devin D, Lu, Jiahe, Aral, Mert, Vahdat, Dan, Ponzo, Sonia, Plans, David“…There was a 31% relative reduction in risk of all-cause mortality per decile of increasing C-Score (hazard ratio of 0.69, 95% CI 0.663-0.675). A Cox model integrating age and C-Score had improved discrimination (8 percentage points; c-statistic=0.74) and good calibration. …”
Publicado 2021
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331245por Legaz, Isabel, Bernardo, María Victoria, Alfaro, Rafael, Martínez-Banaclocha, Helios, Galián, Jose Antonio, Jimenez-Coll, Victor, Boix, Francisco, Mrowiec, Anna, Salmeron, Diego, Botella, Carmen, Parrado, Antonio, Moya-Quiles, María Rosa, Minguela, Alfredo, Llorente, Santiago, de la Peña-Moral, Jesús, Muro, Manuel“…The donor-specific human leukocyte antigen (HLA) antibody (DSA) response to a renal allograft is not fully understood yet. mTOR complex has been described in the accommodation or rejection of transplants and integrates responses from a wide variety of signals. …”
Publicado 2021
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331246por Desai, Anjali Varma, Michael, Chelsea L, Kuperman, Gilad J, Jordan, Gregory, Mittelstaedt, Haley, Epstein, Andrew S, Connor, MaryAnn, B Villar, Rika Paula, Bernal, Camila, Kramer, Dana, Davis, Mary Elizabeth, Chen, Yuxiao, Malisse, Catherine, Markose, Gigi, Nelson, Judith E“…At Memorial Sloan Kettering Cancer Center (MSK), we have integrated and systematized health-related values discussions led by oncology nurses for newly diagnosed cancer patients as part of routine comprehensive cancer care. …”
Publicado 2021
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331247por Miranda, Rose, Smets, Tinne, Van Den Noortgate, Nele, van der Steen, Jenny T., Deliens, Luc, Payne, Sheila, Szczerbińska, Katarzyna, Pautex, Sophie, Van Humbeeck, Liesbeth, Gambassi, Giovanni, Kylänen, Marika, Van den Block, Lieve“…BACKGROUND: ‘PACE Steps to Success’ is a multicomponent training program aiming to integrate generalist and non-disease-specific palliative care in nursing homes. …”
Publicado 2021
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331248por Mirea, Dan-Mircea, Martin-Key, Nayra A, Barton-Owen, Giles, Olmert, Tony, Cooper, Jason D, Han, Sung Yeon Sarah, Farrag, Lynn P, Bell, Emily, Friend, Lauren V, Eljasz, Pawel, Cowell, Daniel, Tomasik, Jakub, Bahn, Sabine“…CONCLUSIONS: Our results suggest that completing a web-based mental health assessment and receiving personalized psychoeducation are associated with subjective mental health improvements, facilitated by increased self-awareness and subsequent use of self-help interventions. Integrating web-based mental health assessments within primary and/or secondary care services could benefit patients further and expedite earlier diagnosis and effective treatment. …”
Publicado 2021
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331249por Li, Shun, Wu, Bin, Ling, Yun, Guo, Mingquan, Qin, Boyin, Ren, Xiaonan, Wang, Chao, Yang, Hua, Chen, Lixiang, Liao, Yixin, Liu, Yang, Peng, Xiuhua, Xu, Chunhua, Wang, Zhenyan, Shen, Yinzhong, Chen, Jun, Liu, Li, Niu, Bowen, Zhu, Mengmin, Liu, Lingling, Li, Feng, Zhu, Tongyu, Zhu, Zhaoqin, Zhou, Xiaohui, Lu, Hongzhou“…In the CD8(+)T cells, activation markers, such as CD69 and HLA class II genes (HLA-DRA, HLA-DRB1, and HLA-DRB5), were significantly upregulated in SCPs. An integrated analysis of the data from scATAC-seq and scRNA-seq showed some consistency between the approaches. …”
Publicado 2021
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331250por Hollander, Justin B, Folta, Sara C, Graves, Erin Michelle, Allen, Jennifer D, Situ, Minyu“…In future studies, it will be important to use an app that integrates with a wearable physical activity device. …”
Publicado 2021
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331251por Xiao, Jian, Li, Wenyun, Huang, Yan, Huang, Mengli, Li, Shanshan, Zhai, Xiaohui, Zhao, Jing, Gao, Chan, Xie, Wenzhuan, Qin, Hao, Cai, Shangli, Bai, Yuezong, Lan, Ping, Zou, Yifeng“…Here we aim to establish a strategy that integrates MSI and TMB determination for colorectal cancer (CRC) in one single assay. …”
Publicado 2021
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331252por Lambert, Sylvie D., Duncan, Lindsay R., Ellis, Janet, Robinson, John Wellesley, Sears, Carly, Culos-Reed, Nicole, Matthew, Andrew, De Raad, Manon, Schaffler, Jamie Lynn, Mina, Daniel Santa, Saha-Chaudhuri, Paramita, McTaggart-Cowan, Helen, Peacock, Stuart“…Initial acceptability evaluation of TEMPO revealed high user satisfaction, in addition to having a number of potential benefits for participants. After integrating suggested changes to TEMPO, the proposed pilot study aims to further test the acceptability and feasibility of TEMPO. …”
Publicado 2021
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331253por Leal Neto, Onicio, Haenni, Simon, Phuka, John, Ozella, Laura, Paolotti, Daniela, Cattuto, Ciro, Robles, Daniel, Lichand, Guilherme“…BACKGROUND: Multimodal approaches have been shown to be a promising way to collect data on child development at high frequency, combining different data inputs (from phone surveys to signals from noninvasive biomarkers) to understand children’s health and development outcomes more integrally from multiple perspectives. OBJECTIVE: The aim of this work was to describe an implementation study using a multimodal approach combining noninvasive biomarkers, social contact patterns, mobile surveying, and face-to-face interviews in order to validate technologies that help us better understand child development in poor countries at a high frequency. …”
Publicado 2021
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331254por Haddad, Samira M, Souza, Renato T, Cecatti, Jose Guilherme, Barreix, Maria, Tamrat, Tigest, Footitt, Carolyn, Mehl, Garrett L, Syah, Inraini F, Shankar, Anuraj H, Tunçalp, Özge“…Further, the module’s implementation will inform the WHO’s ongoing efforts to create a pathway to adaptive and integrated (Smart) Guidelines in Digital Systems to improve health system quality, coverage, and accountability.…”
Publicado 2020
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331255por Bergman, Matthew E., González-Cabanelas, Diego, Wright, Louwrance P., Walker, Berkley J., Phillips, Michael A.“…Photosynthetic carbon assimilation is the principal experimental observable which integrates important aspects of primary plant metabolism. …”
Publicado 2021
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331256por Dondero, Alessandra, Morini, Martina, Cangelosi, Davide, Mazzocco, Katia, Serra, Martina, Spaggiari, Grazia Maria, Rotta, Gianluca, Tondo, Annalisa, Locatelli, Franco, Castellano, Aurora, Scuderi, Francesca, Sementa, Angela Rita, Eva, Alessandra, Conte, Massimo, Garaventa, Alberto, Bottino, Cristina, Castriconi, Roberta“…Kaplan-Meier analysis on 498 primary NBs selects novel prognostic markers possibly integrating the MFC panel. RESULTS: No false positive are detected, and MFC shows high sensitivity (0.0005%). …”
Publicado 2021
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331257por Handley, Margaret A., Landeros, Jerad, Wu, Cindie, Najmabadi, Adriana, Vargas, Daniela, Athavale, Priyanka“…The study’s purpose was to explore fidelity to pre-determined ‘core’ (e.g. systems integration) and ‘modifiable’ equity components (e.g. health coaching responsiveness, and variation by language) using an adapted implementation fidelity framework. …”
Publicado 2021
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331258“…GO and KEGG analyses were conducted using the online tools from the Database for Annotation, Visualization and Integrated Discovery (DAVID). RESULTS: Compared to the corresponding normal samples, GMFG was significantly upregulated in glioblastoma (GBM), kidney clear cell carcinoma (KIRC), lower grade glioma (LGG), acute myeloid leukemia (LAML), and pancreatic cancer (PAAD), testicular cancer (TGCT), but was downregulated in kidney chromophobe (KICH), lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) (P < 0.05 for all). …”
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331259por North, Frederick, Nelson, Elissa M, Majerus, Rebecca J, Buss, Rebecca J, Thompson, Matthew C, Crum, Brian A“…An electronic health record that integrates appointment scheduling and patient web-based access to medical records creates an opportunity for patient self-scheduling. …”
Publicado 2021
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331260por Beck, Alison K., Baker, Amanda L., Carter, Gregory, Robinson, Laura, McCarter, Kristen, Wratten, Christopher, Bauer, Judith, Wolfenden, Luke, Britton, Benjamin“…This is likely central to the demonstrated success of the EAT intervention in reducing malnutrition and highlights the importance of ensuring that providers are adequately equipped to flexibly integrate intervention elements according to patient need. …”
Publicado 2021
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