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332481Publicado 2023“…METHODS: Clinical data of 11 patients with chemotherapy-resistant advanced PTCL who underwent haplo-HSCT with a TBI+rATG-based conditioning regimen at the Department of Hematology, Shanghai Liquan Hospital and Shanghai Zhaxin Integrated Traditional Chinese and Western Medicine Hospital, from September 2019 to December 2022 were retrospectively analyzed. …”
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332482“…Therefore, to prevent diabetic complications and disabilities, support for patients’ self-management should be emphasized in their integrated care services. Digital services could be involved in the care of patients willing to use them. …”
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332483“…ABSTRACT: Monitoring 100-day in-calf rate (100DICR) is an integral part of the assessment of reproductive performance in year-round calving dairy herds. …”
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332484por Marciano, Laura, Vocaj, Emanuela, Bekalu, Mesfin A, La Tona, Antonino, Rocchi, Giulia, Viswanath, Kasisomayajula“…Opportunities (eg, using mobile approaches in low- and middle-income countries, integration of multimodal data, and improving self-efficacy and self-awareness on mental health) and limitations (eg, absence of theoretical frameworks, difficulty in assessing the reliability and effectiveness of such approaches, and need to appropriately assess the quality of the studies) were further discussed. …”
Publicado 2023
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332485
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332486por Huebner, Angela, Thirumalasetty, Shamini Ramkumar, Schubert, Tina, Naumann, Ronald, Reichardt, Ilka, Rohm, Marie-Luise, Landgraf, Dana, Gembardt, Florian, Hartmann, Michaela F, Wudy, Stefan A, Peitzsch, Mirko, Reisch, Nicole, Koehler, Katrin“…Here we present the first viable and humanized mouse model in which the mouse gene Cyp21a1 is replaced by the human orthologue CYP21A2 in which the human point mutation R484Q is integrated. Twenty-weeks-old homozygous mice show marked adrenal hyperplasia, enhanced expression of the CYP21A2 gene and a weak increase of Cyp11a1 and Cyp11b2 gene expression. …”
Publicado 2023
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332487por Coren, Alison T, Roethle, Mark F, Zhang, Liyun, Pan, Amy Y, Jia, Shuang, Hessner, Martin J, Cabrera, Susanne M“…This may occur by altering gut barrier integrity and/or shifts in microbial taxa/metabolites. …”
Publicado 2023
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332488por De Vincentis, Sara, Bellelli, Alessio, Golinelli, Caterina, Beltrami, Elisa, Monzani, Maria Laura, Magnani, Elisa, Pederzoli, Simone, Pacchioni, Marco, Orsini, Mirko, Diazzi, Chiara, Rochira, Vincenzo“…CONCLUSIONS: The use of an ad hoc designed smartphone App is well-accepted by patients and associated with a good adherence in its use, suggesting positive effects on QoL in AGHD patients. The integration of a smartphone App in the clinical practice is feasible and may help empowering patients with chronic diseases such as AGHD on daily self-monitoring of their disease trend, beyond helping physicians in tailoring the clinical management. …”
Publicado 2023
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332489por Coppens, Gregoire, Vanhorebeek, Ilse, Guïza, Fabian, Derese, Inge, Wouters, Pieter J, Koen, Joosten F, Verbruggen, Sascha C, Van den Berghe, Greet“…This was most pronounced for the hypomethylation within the promotor/5’UTR region of FKBP5, which associated with worse growth, intelligence, visual-motor integration, alertness and memory. Two years after critical illness in children, aberrant DNA methylation within different genes of the HPA axis was detected, some of which may partly be explained by the glucocorticoid treatment given during PICU admission. …”
Publicado 2023
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332490por de Oliveira, Karla Andrade, de Oliveira Andrade, Fabia, Ozgul-Onal, Melike, Yadav, Anil, Onal, Tuna, Jin, Lu, Sengupta, Surojeet, Clarke, Robert“…It has a key role in mitochondrial integrity and function, regulating cell survival, death, and metabolism, regulating the shift to amino-acid and fatty-acid catabolism. …”
Publicado 2023
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332491por Golding, Allan, Correa, Gabriel, Sheker, Evana Valenzuela, Jiang, Rouchen, Hao, Yangyang, Liu, Yang, Huang, Jing, Klopper, Joshua P, Kloos, Richard T, Kennedy, Giulia C, Bimston, David“…Histopathology reports from Afirma Genomic Sequencing Classifier (GSC) algorithm training and from thyroid cancer patients managed at an integrative endocrine surgery community care practice (total 697 and ∼50% from each) were reviewed for invasion and metastases. …”
Publicado 2023
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332492“…We used a Bayesian age period cohort model of integrated nested Laplace approximations to predict the disease burden of GEC through 2044 and obtained the estimated population of China from 2020 to 2050 from the Global Health Data Exchange website. …”
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332493por Aboutalebi, Hossein, Pavlova, Maya, Shafiee, Mohammad Javad, Florea, Adrian, Hryniowski, Andrew, Wong, Alexander“…The proposed approach advances machine learning model design by seamlessly integrating domain expertise with explainability tools, enabling model decisions to be based on key biomarkers. …”
Publicado 2023
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332494por Chatrenet, Antoine, Piccoli, Giorgina, Audebrand, Jean Michel, Torreggiani, Massimo, Barbieux, Julien, Vaillant, Charly, Morel, Baptiste, Durand, Sylvain, Beaune, Bruno“…A statistical parametric mapping approach was performed on the force, impulse and RFD–time curves. The integrated sEMG with time at 0–30, 0–50, 0–100 and 0–200 ms time intervals relative to onset of sEMG activity was extracted and groups were compared separately for each sex. …”
Publicado 2023
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332495por Yang, Le, Yu, Wenji, Wan, Peng, Wang, JingWen, Shao, Xiaoliang, Zhang, Feifei, Yang, Xiaoyu, Chen, Yongjun, Li, Qi, Jiang, Dan, Wang, Yufeng, Jiang, Qi, Wang, Jianfeng, Wang, Yuetao“…Adding high EFV to MPI could predict MACEs more effectively, with a higher concordance index (0.56–0.69, P < 0.01), higher global chi square (7.2–41.4, P < 0.01), positive integrated discrimination improvement (0.10, P < 0.01), and net reclassification index (0.37, P < 0.01). …”
Publicado 2023
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332496por Han, Dingsheng, Li, Yalin, He, Xu, Zhang, Jiacheng, Zhou, Yanru, Zhang, Jiajia, Zhang, Lan“…CONCLUSIONS: A diagnostic regimen integrating tumor markers (AFP, CA19-9) and imaging biomarkers (targetoid restriction on DWI and/or targetoid sign on HBP) using Gd-EOB-DTPA-enhanced MRI could help to differentiate mass-forming ICCs from atypical HCCs and achieve high diagnostic performance of mass-forming ICCs in at-risk patients with the HBV. …”
Publicado 2023
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332497por Meng, Qingtao, Yu, Pengxin, Yin, Siyuan, Li, Xiaofeng, Chang, Yitong, Xu, Wei, Wu, Chunmao, Xu, Na, Zhang, Huan, Wang, Yu, Shen, Hong, Zhang, Rongguo, Zhang, Qingyue“…This study aimed to externally validate an AI-assisted analysis system capable of rapidly evaluating stenosis severity, exploring its potential integration into routine clinical workflows. METHODS: This multicenter study consisted of an internal and external cohort of patients who underwent CCTA scans between April 2017 and February 2023. …”
Publicado 2023
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332498por Patzer, Theresa Sophie, Kunz, Andreas Steven, Huflage, Henner, Gruschwitz, Philipp, Pannenbecker, Pauline, Afat, Saif, Herrmann, Judith, Petritsch, Bernhard, Bley, Thorsten Alexander, Grunz, Jan-Peter“…OBJECTIVES: While established for energy-integrating detector computed tomography (CT), the effect of virtual monoenergetic imaging (VMI) and iterative metal artifact reduction (iMAR) in photon-counting detector (PCD) CT lacks thorough investigation. …”
Publicado 2023
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332499por Huang, Jin, Zhang, Jian-Lin, Ang, Lin, Li, Ming-Cong, Zhao, Min, Wang, Yao, Wu, Qiang“…We used the Metascape tool for enrichment analyses, and ‘WGCNA’ was utilized to establish co-expression networks, selecting the soft threshold power with the ‘pickSoftThreshold’ algorithm. We integrated ten machine learning algorithms and 101 algorithm combinations to identify key genes associated with distant recurrence in BC. …”
Publicado 2023
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332500por Fedele, Emma, Trousset, Victor, Schalk, Thibault, Oliero, Juliette, Fovet, Thomas, Lefevre, Thomas“…Qualitative data will be integrated with quantitative data to identify psycho-socio-judicial trajectories and enhance the prediction of PTSD. …”
Publicado 2023
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