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332801“…CDI is also associated with AML in cases that involve monosomy 7 and inversion 3q21q26, both of which result in ectopic viral integration site 1 (EVI-1) overexpression. It is postulated that EVI-1 overexpression interferes with hypothalamic secretion of antidiuretic hormone (ADH) or may lead to its inactivation. …”
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332802por Fleseriu, Maria, Dreval, Akexander V, Pokramovich, Yulia, Bondar, Irina, Isaeva, Elena, Molitch, Mark E, Macut, Djuro P, Leonova, Nina, Raverot, Gerald, Gilgun-Sherki, Yossi, Ludlam, William H, Patou, Gary, Haviv, Asi, Gordon, Murray B, Verbovoy, Andrey, Dogadin, Sergey A, Biermasz, Nienke, Strasburger, Christian J, Melmed, Shlomo“…Methods: Patients who fail to respond to 80 mg/d OOC for ≥2 weeks during the 26-week Run-in phase, or ineligible to enter the RCT on 80 mg/d OOC, due to inadequate biochemical control (insulin-like growth factor I [IGF-I] ≥1.3 × upper limit of normal [ULN] to <2 × ULN or IGF-I <1.3 × ULN and mean integrated growth hormone [GH] ≥2.5 ng/mL) were eligible for sub-study combination OOC 80 mg/d and cabergoline ≤3.5 mg/wk (fixed algorithm) for 36 weeks. …”
Publicado 2021
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332803por Joseph, Rodney P, Ainsworth, Barbara E, Hollingshead, Kevin, Todd, Michael, Keller, Colleen“…Features available on the Smart Walk app include personal profile pages, multimedia PA promotion modules, discussion board forums, and an activity tracking feature that integrates with Fitbit activity monitors. Self-reported PA and social cognitive theory mediators targeted by the intervention (ie, self-regulation, behavioral capability, outcome expectations, self-efficacy, and social support) were assessed at baseline and at 4 months. …”
Publicado 2021
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332804“…Our system aims to achieve a high level of performance by integrating heuristics and advanced information extraction methods. …”
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332805por Bogan, Carolyn, Jennings, Lindsey, Haynes, Louise, Barth, Kelly, Moreland, Angela, Oros, Marla, Goldsby, Sara, Lane, Suzanne, Funcell, Chanda, Brady, Kathleen“…The aim of this pilot program was to foundationally integrate universal screening, brief interventions and referral to treatment (SBIRT) in hospital EDs to identify patients with at-risk substance use. …”
Publicado 2020
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332806por Jiang, Minlin, Wu, Chunyan, Zhang, Liping, Sun, Chenglong, Wang, Hao, Xu, Yi, Sun, Hui, Zhu, Jun, Zhao, Wencheng, Fang, Qiyu, Yu, Jia, Chen, Peixin, Wu, Shengyu, Zheng, Zixuan, He, Yayi, Zhou, Caicun“…Then, relapse prediction system integrating clinical staging and immune risk score was established, which performed well in different cohorts. …”
Publicado 2021
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332807por González-Rodríguez, Patricia, Cheray, Mathilde, Füllgrabe, Jens, Salli, Maria, Engskog-Vlachos, Pinelopi, Keane, Lily, Cunha, Virginia, Lupa, Agata, Li, Wenbo, Ma, Qi, Dreij, Kristian, Rosenfeld, Michael G., Joseph, Bertrand“…Thus, this pathway can be seen as a central component of the integrated and adaptive stress response. Here, we report that even brief induction of autophagy is coupled in vitro to a persistent downregulation of the expression of MAP1LC3 isoforms, which are key components of the autophagy core machinery. …”
Publicado 2020
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332808por Baldino, Salvatore, Giboulot, Steven, Lovison, Denise, Nedden, Hans Günter, Pöthig, Alexander, Zanotti-Gerosa, Antonio, Zuccaccia, Daniele, Ballico, Maurizio, Baratta, WalterEnlace del recurso
Publicado 2021
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332809por Martinez, William, Hackstadt, Amber J, Hickson, Gerald B, Rosenbloom, S Trent, Elasy, Tom A“…By embedding MDC into Epic’s MyChart platform with more than 127 million patient records, our intervention is directly integrated into routine care, highly scalable, and sustainable. …”
Publicado 2021
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332810“…Study implications include integrating app use throughout the classroom sessions to build narrative-generating skills across the program and increasing the number of narratives produced, which should in turn increase the program’s behavior change potency.…”
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332811por Núñez, Eduardo R., Caverly, Tanner J., Zhang, Sanqian, Glickman, Mark E., Qian, Shirley X., Boudreau, Jacqueline H., Slatore, Christopher G., Miller, Donald R., Wiener, Renda Soylemez“…CONCLUSIONS AND RELEVANCE: In this cohort study that captured follow-up care from the integrated VHA health care system and Medicare, less than two-thirds of patients received timely recommended follow-up after initial LCS, with higher risk of delayed or absent follow-up among marginalized populations, such as Black individuals, individuals with mental health disorders, and individuals with low income, that have long experienced disparities in lung cancer outcomes. …”
Publicado 2021
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332812por Ku, Geoffrey Y., Kemel, Yelena, Maron, Steve B., Chou, Joanne F., Ravichandran, Vignesh, Shameer, Zarina, Maio, Anna, Won, Elizabeth S., Kelsen, David P., Ilson, David H., Capanu, Marinela, Strong, Vivian E., Molena, Daniela, Sihag, Smita, Jones, David R., Coit, Daniel G., Tuvy, Yaelle, Cowie, Kendall, Solit, David B., Schultz, Nikolaus, Hechtman, Jaclyn F., Offit, Kenneth, Joseph, Vijai, Mandelker, Diana, Janjigian, Yelena Y., Stadler, Zsofia K.“…MAIN OUTCOMES AND MEASURES: Presence or absence of LP/P variants in up to 88 genes associated with cancer predisposition syndromes as identified by targeted sequencing (Memorial Sloan Kettering–Integrated Mutation Profiling of Actionable Cancer Targets). …”
Publicado 2021
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332813por Mehata, Suresh, Tamang, Man Kumar, Parajuli, Kedar Raj, Rayamajhee, Binod, Yadav, Uday Narayan, Mehta, Ranju Kumari, Singh, Dipendra Raman“…We believe that intervention programs to address zinc deficiency should not be isolated. Instead, integrated approaches are beneficial to improve overall micronutrient status, such as encouraging dietary diversity, providing livelihood opportunities to the unemployed, micronutrient supplementation to vulnerable populations, and consumption of zinc-rich animal-based foods.…”
Publicado 2021
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332814“…CONCLUSION: It might be suggested that TM may have a protective impact on the small intestine histomorphometry and epithelial integrity of broilers during post-hatch exposure to thermal stress.…”
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332815por Cunha, Bruna Carolina Rodrigues, Rodrigues, Kamila Rios Da Hora, Zaine, Isabela, da Silva, Elias Adriano Nogueira, Viel, Caio César, Pimentel, Maria Da Graça Campos“…METHODS: We conducted the design and evaluation of the ESPIM method and model alongside a software system comprising integrated web and mobile apps. A participatory design approach with stakeholders included early software prototype, predesign interviews with 12 health specialists, iterative design sustained by the software as an instance of the method’s conceptual model, support to 8 real case studies, and postdesign interviews. …”
Publicado 2021
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332816por Sax, Dana R., Rana, Jamal S., Mark, Dustin G., Huang, Jie, Collins, Sean P., Liu, Dandan, Storrow, Alan B., Reed, Mary E.“…METHODS AND RESULTS: We conducted a retrospective, multicentre study of adult ED patients with AHF from 2017 to 2018 in an integrated healthcare system with 21 hospitals. Among patients with known EF, our primary outcome was 30 day all‐cause mortality, comparing patients with heart failure with preserved EF (HFpEF) and heart failure with reduced EF (HFrEF), adjusted for known risk factors. …”
Publicado 2021
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332817por Randelli, Pietro, Stoppani, Carlo Alberto, Nocerino, Elisabetta, Menon, Alessandra, Compagnoni, Riccardo“…Musculoskeletal ultrasound had been used to evaluate the integrity of the repaired cuff. RESULTS: A number of 38 (71%) patients (PRP=17; control=21) with a median age of 71 [64.75-76.50] years have been evaluated. …”
Publicado 2021
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332818por Pimentel, Camilla B, Clark, Valerie, Baughman, Amy W, Berlowitz, Dan R, Davila, Heather, Mills, Whitney L, Mohr, David C, Sullivan, Jennifer L, Hartmann, Christine W“…METHODS: We will conduct interviews with staff at 3 CLCs (1 1-star CLC, 1 3-star CLC, and 1 5-star CLC) to identify staff actions taken in response to their CLCs’ public data; staff’s commitment to or difficulties with using CLC Compare; and factors that motivate staff to improve CLC quality. We will integrate these findings with our conceptual framework to adapt and expand a community nursing home survey to the current CLC environment. …”
Publicado 2021
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332819“…The forecast performance was also compared with an autoregressive integrated moving average (ARIMA) model in the same cross-validation time frame. …”
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332820por Gabor, Lisa, Gowthaman, Divya, Gressel, Gregory, Kuo, Dennis Yi-Shin, Nevadunsky, Nicole, Bansal, Nisha“…We predict that gynecologic oncology practice patterns will shift to include telemedicine as an integral part of patient care, even after SARS-COV-2 is no longer prevalent in the community.…”
Publicado 2021
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