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  1. 333081
    “…This allows genomics applications developed in different programming languages to communicate in-memory without having to access disk storage and avoiding (de)-serialization and copy overheads. IMPLEMENTATION: We integrate Apache Arrow in-memory based Sequence Alignment/Map (SAM) format and its shared memory objects store library in widely used genomics high throughput data processing applications like BWA-MEM, Picard and GATK to allow in-memory communication between these applications. …”
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    Optimizing performance of GATK workflows using Apache Arrow In-Memory data framework
  2. 333082
    “…CONCLUSIONS: Findings highlight the need to integrate alcohol- and substance-focused initiatives into PrEP care for gbMSM. …”
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    Alcohol consumption, substance use, and depression in relation to HIV Pre-Exposure Prophylaxis (PrEP) nonadherence among gay, bisexual, and other men-who-have-sex-with-men
  3. 333083
    “…An embedded ethnography will be included to capture context and process data to inform the implementation assessment and development of a scale and spread strategy. An Integrated Knowledge Translation approach is taken to inform the study. …”
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    Building a Digital Bridge to Support Patient-Centered Care Transitions From Hospital to Home for Older Adults With Complex Care Needs: Protocol for a Co-Design, Implementation, and Evaluation Study
  4. 333084
    “…Coverage, use and physical integrity of LLINs were assessed in households, then cone assays were used to test for their bio-efficacy on both the reference insecticide-susceptible Kisumu strain and on field F1 An. gambiae (s.l.) …”
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    Insights into factors sustaining persistence of high malaria transmission in forested areas of sub-Saharan Africa: the case of Mvoua, South Cameroon
  5. 333085
    “…The multidimensional causes and drivers of anemia in women require an integrated approach to help ameliorate anemia and its negative health effects on the women’s health. …”
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    Intersection of HIV and Anemia in women of reproductive age: a 10-year analysis of three Zimbabwe demographic health surveys, 2005–2015
  6. 333086
    “…We hypothesised that the glucagon–alanine index, an indicator of the functional integrity of the liver–alpha cell axis, would associate with liver fat and insulin resistance in our cohort of women with low levels of liver fat. …”
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    The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels
  7. 333087
    “…CONCLUSIONS: The designed approach could have positive improvements in PTSD symptoms, (OH) and (OHRQoL) of displaced children. Integration between (MH) and (OH) services should be considered during and after humanitarian crises to prevent immediate and long-term MH and OH problems. …”
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    A short-term approach for promoting oral health of internally displaced children with PTSD: the key is improving mental health—results from a quasi-randomized trial
  8. 333088
    “…METHODS: Guided by the integrated-Promoting Action on Research Implementation in Health Services (i-PARIHS) framework, we interviewed stakeholders at low-adopting VHA facilities prior to external facilitation, employed a rapid qualitative analytic process, presented findings during facility visits, and collaboratively created facilitation action plans to achieve goals set by the facilities that would increase M-OUD uptake. …”
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    Early impacts of a multi-faceted implementation strategy to increase use of medication treatments for opioid use disorder in the Veterans Health Administration
  9. 333089
    “…DRC government should scale up malaria control strategy by integrating efficient indoor and outdoor preventive measures and improve malaria care accessibility.…”
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    Malaria rapid diagnostic test (HRP2/pLDH) positivity, incidence, care accessibility and impact of community WASH Action programme in DR Congo: mixed method study involving 625 households
  10. 333090
    por Martínez-Gamboa, Areli, Niembro-Ortega, María Dolores, Torres-González, Pedro, Santiago-Cruz, Janeth, Velázquez-Zavala, Nancy Guadalupe, Rangel-Cordero, Andrea, Crabtree-Ramírez, Brenda, Gamboa-Domínguez, Armando, Reyes-Gutiérrez, Edgardo, Reyes-Terán, Gustavo, Lozano-Fernandez, Víctor Hugo, Ahumada-Topete, Víctor Hugo, Martínez-Ayala, Pedro, Manríquez-Reyes, Marisol, Ramírez-Hinojosa, Juan Pablo, Rodríguez-Zulueta, Patricia, Hernández-León, Christian, Ruíz-Quiñones, Jesús, Rivera-Martínez, Norma Eréndira, Chaparro-Sánchez, Alberto, Andrade-Villanueva, Jaime, González-Hernández, Luz Alicia, Cruz-Martínez, Sofia, Flores-Barrientos, Oscar, Gaytán-Martínez, Jesús Enrique, Magaña-Aquino, Martín, Cervantes-Sánchez, Axel, Olivas-Martínez, Antonio, Araujo-Meléndez, Javier, del Rocío Reyes-Montes, María, Duarte-Escalante, Esperanza, Frías-De León, María Guadalupe, Ramírez, José Antonio, Taylor, María Lucia, de León-Garduño, Alfredo Ponce, Sifuentes-Osornio, José
    Publicado 2021
    “…CONCLUSIONS/SIGNIFICANCE: The cHGEI IMMY and MVHUALFA tests showed excellent performance for the diagnosis of PDH in PLWHIV. The integration of these tests in clinical laboratories will certainly impact on early diagnosis and treatment.…”
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    Diagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico
  11. 333091
    “…To infer potential disease-associated m(7)G sites, we then proposed a heterogeneous network-based model, m(7)G Sites and Diseases Associations Inference (m(7)GDisAI) model. m(7)GDisAI predicts the potential disease-associated m(7)G sites by applying a matrix decomposition method on heterogeneous networks which integrate comprehensive similarity information of m(7)G sites and diseases. …”
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    m(7)GDisAI: N7-methylguanosine (m(7)G) sites and diseases associations inference based on heterogeneous network
  12. 333092
    “…We next analyzed the PIK3CA + HMCN1 + LRP1B mutation combination with marginal effects in STAD patients by Kaplan-Meier, transcriptomic differential, and KEGG integrated pathway enrichment analyses. Lastly, we adopted a connectivity map (CMap) to find potentially useful drugs specifically targeting LRP1B mutation in STAD patients. …”
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    Identification of PIK3CA multigene mutation patterns associated with superior prognosis in stomach cancer
  13. 333093
    “…Of interest, correlation between white matter β-amyloid PET uptake and (+)-[(18)F]Flubatine binding indicated an association between white matter integrity and availability of α4β2 nAChRs. Overall, (+)-[(18)F]Flubatine showed favorable characteristics and has therefore the potential to serve as α4β2 nAChR–targeting PET ligand in further clinical trials. …”
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    (+)-[(18)F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls
  14. 333094
    “…We recommend a low-dose high frequency strategy to skills building with simulation and e-learning. A gender integrated approach to training may help ensure female trainees are exposed to critical training components. …”
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    Factors related to the practice of vacuum-assisted birth: findings from provider interviews in Kigoma, Tanzania
  15. 333095
    “…CONCLUSIONS: We recommend maternal and perinatal death audits in all health facilities; respectful, woman-centered care as a critical criterion of RBF initiatives; local administration of health worker allowances and incentives; and integration of CHWs into the healthcare system. There is an urgent need to include preconception care in the SRMNH care continuum and studies in LLMICs. …”
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    How can human resources for health interventions contribute to sexual, reproductive, maternal, and newborn healthcare quality across the continuum in low- and lower-middle-income countries? A systematic review
  16. 333096
    “…Affordable and scalable ways to adopt a sample- or case-based approach across the network should be explored and clinical data should be integrated to help provide more accurate inferences of the surveillance data. …”
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    Antimicrobial susceptibility testing results from 13 hospitals in Viet Nam: VINARES 2016–2017
  17. 333097
    “…While subacutely after sSAH, higher CSF levels of the vasodilator CGRP are supposed to be protective against vasospasm-associated cerebral ischemia, from a psychopathological point of view, our results suggest an involvement of CSF CGRP in the dysregulation of higher integrated behavior.…”
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    Endogenous calcitonin gene-related peptide in cerebrospinal fluid and early quality of life and mental health after good-grade spontaneous subarachnoid hemorrhage—a feasibility series
  18. 333098
    “…Structured training of end-of-life care needs to be integrated within curricula and in-service training. …”
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    Knowledge and attitudes about end-of-life decisions, good death and principles of medical ethics among doctors in tertiary care hospitals in Sri Lanka: a cross-sectional study
  19. 333099
    “…The study was approved by the Research Ethics Committee on May 27, 2020 (Integrated Research Application System number: 283024, Research Ethics Committee reference number: 20/NW/0266) and badged as National Institute of Health Research Urgent Public Health Study on October 14, 2020. …”
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    Predicting Risk of Hospital Admission in Patients With Suspected COVID-19 in a Community Setting: Protocol for Development and Validation of a Multivariate Risk Prediction Tool
  20. 333100
    “…Until then though, human-based decision-making profoundly impacts patient care and – although not suggested in the updated European Society of Gastrointestinal Endoscopy (ESGE) European curriculum 8 9 – it should be an integral part of CE training. Frequently, interpretation of CE images by experts or at least experienced readers differs. …”
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    Scoring systems in clinical small-bowel capsule endoscopy: all you need to know!
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