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333321“…Though we can not prove it at the present time, we believe that the tunica lesion is an integral part of this disease in guinea pigs, and not an accidental accompaniment. …”
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333322“…Consequently, a vaccine is urgently needed. Integral to vaccine design is an understanding of the interactions of the pathogen and host immune response. …”
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333323por Johanson, Conrad E, Duncan, John A, Klinge, Petra M, Brinker, Thomas, Stopa, Edward G, Silverberg, Gerald D“…This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption. …”
Publicado 2008
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333324por Cranage, Martin, Sharpe, Sally, Herrera, Carolina, Cope, Alethea, Dennis, Mike, Berry, Neil, Ham, Claire, Heeney, Jonathan, Rezk, Naser, Kashuba, Angela, Anton, Peter, McGowan, Ian, Shattock, Robin“…To prevent mucosal transmission of HIV, a microbicide/ARV should ideally act locally at and near the virus portal of entry. As part of an integrated rectal microbicide development programme, we have evaluated rectal application of the nucleotide reverse transcriptase (RT) inhibitor tenofovir (PMPA, 9-[(R)-2-(phosphonomethoxy) propyl] adenine monohydrate), a drug licensed for therapeutic use, for protective efficacy against rectal challenge with simian immunodeficiency virus (SIV) in a well-established and standardised macaque model. …”
Publicado 2008
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333325“…METHODS: A mixed method approach integrating survey and narrative data was used. Survey data were collected about attitudes toward sharing PCHR information for health research from early adopters (n = 151) of a live PCHR populated with medical records and self-reported behavioral and social data. …”
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333326“…For this reason, some recent predictive models are deliberately designed to integrate multiple heterogeneous data sources for exploiting multi-aspect protein feature information. …”
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333327por Molina, Carlos, Zaman-Allah, Mainassara, Khan, Faheema, Fatnassi, Nadia, Horres, Ralf, Rotter, Björn, Steinhauer, Diana, Amenc, Laurie, Drevon, Jean-Jacques, Winter, Peter, Kahl, Günter“…We demonstrate that these targets can be integrated into breeding schemes by micro-arrays and RT-PCR assays downstream of the generation of 26 bp tags by SuperSAGE.…”
Publicado 2011
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333328por Wang, Fusheng, Kong, Jun, Cooper, Lee, Pan, Tony, Kurc, Tahsin, Chen, Wenjin, Sharma, Ashish, Niedermayr, Cristobal, Oh, Tae W, Brat, Daniel, Farris, Alton B, Foran, David J, Saltz, Joel“…One major obstacle which tends to reduce wider adoption of these new technologies throughout the clinical and scientific communities is the challenge of managing, querying, and integrating the vast amounts of data resulting from the analysis of large digital pathology datasets. …”
Publicado 2011
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333329“…These separate systems were integrated into a coding framework model called the communication-based influence components model. …”
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333330por Krallinger, Martin, Vazquez, Miguel, Leitner, Florian, Salgado, David, Chatr-aryamontri, Andrew, Winter, Andrew, Perfetto, Livia, Briganti, Leonardo, Licata, Luana, Iannuccelli, Marta, Castagnoli, Luisa, Cesareni, Gianni, Tyers, Mike, Schneider, Gerold, Rinaldi, Fabio, Leaman, Robert, Gonzalez, Graciela, Matos, Sergio, Kim, Sun, Wilbur, W John, Rocha, Luis, Shatkay, Hagit, Tendulkar, Ashish V, Agarwal, Shashank, Liu, Feifan, Wang, Xinglong, Rak, Rafal, Noto, Keith, Elkan, Charles, Lu, Zhiyong, Dogan, Rezarta Islamaj, Fontaine, Jean-Fred, Andrade-Navarro, Miguel A, Valencia, Alfonso“…Most ACT teams explored machine learning methods, some of them also used lexical resources like MeSH terms, PSI-MI concepts or particular lists of verbs and nouns, some integrated NER approaches. For the IMT, a total of 42 runs were evaluated by comparing systems against manually generated annotations done by curators from the BioGRID and MINT databases. …”
Publicado 2011
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333331por Pannone, Giuseppe, Rodolico, Vito, Santoro, Angela, Lo Muzio, Lorenzo, Franco, Renato, Botti, Gerardo, Aquino, Gabriella, Pedicillo, Maria Carmela, Cagiano, Simona, Campisi, Giuseppina, Rubini, Corrado, Papagerakis, Silvana, De Rosa, Gaetano, Tornesello, Maria Lina, Buonaguro, Franco M, Staibano, Stefania, Bufo, Pantaleo“…HPV-DNA genotyping by consensus HPV-DNA PCR methods (Consensus PCR); and 3 viral integration into the host by in situ hybridization method (ISH). …”
Publicado 2012
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333332por Chrzanowska, Krystyna H, Gregorek, Hanna, Dembowska-Bagińska, Bożenna, Kalina, Maria A, Digweed, Martin“…Combined cellular and humoral immunodeficiency with recurrent sinopulmonary infections, a strong predisposition to develop malignancies (predominantly of lymphoid origin) and radiosensitivity are other integral manifestations of the syndrome. The NBN gene codes for nibrin which, as part of a DNA repair complex, plays a critical nuclear role wherever double-stranded DNA ends occur, either physiologically or as a result of mutagenic exposure. …”
Publicado 2012
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333333por Robling, Mike, McNamara, Rachel, Bennert, Kristina, Butler, Christopher C, Channon, Sue, Cohen, David, Crowne, Elizabeth, Hambly, Helen, Hawthorne, Kamila, Hood, Kerenza, Longo, Mirella, Lowes, Lesley, Pickles, Tim, Playle, Rebecca, Rollnick, Stephen, Thomas-Jones, Emma, Gregory, John W“…Analysis was by intention to treat. An integrated process evaluation included audio recording a sample of 86 routine consultations to assess skills shortly after training (intervention group) and at one year follow-up (intervention and control group). …”
Publicado 2012
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333334por Gustafson, David, Wise, Meg, Bhattacharya, Abhik, Pulvermacher, Alice, Shanovich, Kathleen, Phillips, Brenda, Lehman, Erik, Chinchilli, Vernon, Hawkins, Robert, Kim, Jee-Seon“…Self-efficacy was not significant (alpha = .080, P = .14; beta = .476, P = .01); neither was information competence (alpha = .079, P = .09; beta = .063, P = .64). CONCLUSIONS: Integrating telephone case management with eHealth benefited pediatric asthma control, though not medication adherence. …”
Publicado 2012
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333335por Lau, Annie YS, Proudfoot, Judith, Andrews, Annie, Liaw, Siaw-Teng, Crimmins, Jacinta, Arguel, Amaël, Coiera, Enrico“…METHODS: A one-group pre/posttest online prospective study was conducted on a university campus to measure use of a PCHMS for physical and emotional well-being needs during a university academic semester (July to November 2011). The PCHMS integrated an untethered personal health record (PHR) with well-being journeys, social forums, polls, diaries, and online messaging links with a health service provider, where journeys provide information for consumer participants to engage with clinicians and health services in an actionable way. 1985 students and staff aged 18 and above with access to the Internet were recruited online. …”
Publicado 2013
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333336“…OP&R epidemiologist review and analyze this data for disease surveillance purposes in conjunction with other data sources in ESSENCE (emergency department chief complaints, poison control center data, thermometer sales data, and over-the-counter medication sales data). Integrating school absenteeism data will provide a more complete analysis of potential public health threats. …”
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333337“…These weekly statuses were then compared with outbreaks reported in Merlin’s fully integrated outbreak reporting system and with outbreak reports submitted to EpiCom, Florida’s EpiX or health alert network. …”
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333338por Mandl, Kenneth D.“…Public health agencies wishing to deliver alerts to clinicians also must engage in an endless array of one-off systems integrations. Despite a $48B investment in HIT, and meaningful use criteria requiring reporting to biosurveillance systems, most vendor electronic health records are architected monolithically, making modification difficult for hospitals and physician practices. …”
Publicado 2013
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333339por Coberly, Jacqueline S., Fink, Clayton R., Elbert, Eugene, Yoon, In-Kyu, Velasco, John M., Tomayo, Agnes, Roque, V., Ygano, S., Macasoco, Durinda, Lewis, Sheri“…The first was daily dengue fever incidence for Cebu City and the NCR taken from the Philippines Integrated Disease Surveillance and Response System (PIDSR). …”
Publicado 2013
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333340por Gundlapalli, Adi, Divita, Guy, Carter, Marjorie, Shen, Shuying, Palmer, Miland, Forbush, Tyler, South, Brett, Redd, Andrew, Sauer, Brian, Samore, Matthew“…METHODS: A corpus of 1000 free text medical notes from the VA integrated electronic medical record (CPRS) was reviewed to identify commonly used templates. …”
Publicado 2013
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