“…METHODS: In the PrEP Implementation in Young Women and Adolescents program, which integrated pre-exposure prophylaxis (PrEP) into antenatal care, postnatal care, and family planning facilities in Kisumu County, Kenya, HIV-negative women 14 years of age or older were offered oral HIV self-tests (HIVSTs) to take home to male partners. …”
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“…PURPOSE: The importance of meniscus integrity in the prevention of early osteoarthritis is well known, and preservation is accepted as the primary goal. …”
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“…These changes will require an integrated government response to improve primary care and undertake required multisectoral action to tackle key risks. …”
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“…High-sensitivity C-reactive protein (hs-CRP) levels were also determined as broader changes in inflammatory pathways may potentially impact circulating ferritin levels. Results were integrated into an existing database of metabolic parameters. …”
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“…For clinical outcome analyses, the online tool Kaplan-Meier Plotter and an integrated response database were used. RESULTS: We found that JQ1 modified the expression of stemness-related genes in two TNBC-derived cell lines, MDA-MB-231 and BT549. …”
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“…Self-generation of unitization was effective in improving task performance when assistance was provided rather than merely encouraged, suggesting that patients may benefit from guidance generating their own unitizations rather than integrating this strategy on their own. These findings should be replicated in a larger sample, and strategies to provide effective self-generation of unitization should be explored. …”
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“…DISCUSSION: Our finding is the first to integrate polygenic and poly-environmental markers with MRI parameters to demonstrate that the interaction of these cumulated risk factors leads to the emergence of subclinical symptoms through changes in brain structure. …”
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“…Oxenkrug G, Cornicelli J, van der Hart M, et al. 2016. Integr Mol Med, 3: 761. Schwarcz, R., Rassoulpour, A., Wu, H.Q., et al. 2001. …”
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“…Although association between NSS and cognitive performance is well recognized in schizophrenia, the links between these subtle neurological sensory integration/motor deficits and cognitive abilities to represent space (spatial memory) has not been studied yet. …”
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“…DISCUSSION: These findings provide the first evidence for state-independent connectome-wide associations of schizophrenia polygenic risk at the systems level and suggest that disrupted integration of sensori-cognitive information may be a hallmark of genetic effects on the brain that contributes to the pathogenesis of schizophrenia.…”
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“…Repeated-measures ANOVA revealed that evidence integration (EI) improved after MCT (d = 0.57) and sustained at 1 month (p = 0.042) and 6 months (p = 0.041). …”
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“…BACKGROUND: In general, MR spectroscopy (MRS) studies report alterations of both glutamatergic indices and NAA not only in first episode psychosis and established schizophrenia but also in high risk populations, suggesting that altered excitatory neurotransmission and loss of neuronal integrity are early pathophysiological processes. However, interpretation of these findings is limited by the region-of-interest approach of current MRS techniques, limiting the measurement of metabolites to delimited cerebral volumes, selected by a priori hypotheses. …”
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“…Constructing the immune signature for schizophrenia for clinical use and research; an integrative review translating descriptives into diagnostics. …”
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“…Medication seems to have only a small, localized effect on corpus callosum WM integrity. However, since our analysis used cross-sectional CPZ measures, future studies should include measurements of lifetime dosage. …”
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“…In healthy subjects, cognitive flexibility has been related to medial prefrontal cortex (PFC) function, while cognitive stability was related to lateral PFC integrity with both brain regions being modulated by striatal activity. …”
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“…The World Health Organization (WHO) has promoted the Integrated Vector Management (IVM) approach through its Global Vector Control Response 2017–2030. …”
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“…In comparison with the best classifier model that comprised only clinical parameters (ROC AUC: 0.67; 95% CI: 0.55–0.79), both models performed better in predicting fall risk, with an estimated Net Reclassification Improvement (NRI) of 0.30 and 0.31 (p = 0.02), respectively, and an estimated Integrated Discrimination Improvement (IDI) of 0.32 and 0.27 (p<0.001), respectively. …”
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“…For the early-phase patients, integrating radiomics signature with clinical risk factors can achieve a more accurate prediction of individual poor prognostic outcome, which enables appropriate management and surveillance of COVID-19.…”
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“…Hence, KP programs could include integrated HIV-NCD screening and care in their guidelines.…”
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“…Recently, we developed the prototype of a web-based, self-monitoring gamified mobile app tailored for adolescents: the INTERACCT (Integrating Entertainment and Reaction Assessment into Child Cancer Therapy) app. …”
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