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333581“…METHODS: Real-time quantitative polymerase chain reaction and western blotting were performed to examine gene and protein levels in CRC cells and clinical tissues (collected from CRC patients who underwent surgery in the Department of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, between 2016 and 2018, n = 24). …”
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333582por Li, Bing, Chen, Junying, Guo, Wei, Mao, Ronghu, Zheng, Xiaoli, Cheng, Xiuyan, Cui, Tiantian, Lou, Zhaoyang, Wang, Ting, Li, Dingjie, Tao, Hongyan, Lei, Hongchang, Ge, Hong“…Dosimetric verification for all plans was carried out using the portal dosimetry system integrated into the Eclipse treatment planning system based on the electronic portal imaging devices. …”
Publicado 2021
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333583por Liu, Dengying, Chen, Zhenliang, Zhao, Wei, Guo, Longyu, Sun, Hao, Zhu, Kai, Liu, Guanglei, Shen, Xiuping, Zhao, Xiaoduo, Wang, Qishan, Ma, Peipei, Pan, Yuchun“…In this study, two complementary approaches, integrated haplotype score (iHS) and runs of homozygosity (ROH), were applied for the detection of selection signatures within the genome using genotyping by genome-reduced sequence data from 1092 cows. …”
Publicado 2021
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333584por Liu, Huifang, Ho, Philip Wing-Lok, Leung, Chi-Ting, Pang, Shirley Yin-Yu, Chang, Eunice Eun Seo, Choi, Zoe Yuen-Kiu, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong“…Mitochondrial dysfunction causes energy deficiency and nigrostriatal neurodegeneration which is integral to the pathogenesis of Parkinson disease (PD). …”
Publicado 2020
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333585por Kelly, Peter J, Beck, Alison K, Deane, Frank P, Larance, Briony, Baker, Amanda L, Hides, Leanne, Manning, Victoria, Shakeshaft, Anthony, Neale, Joanne, Kelly, John F, Oldmeadow, Christopher, Searles, Andrew, Palazzi, Kerrin, Lawson, Kenny, Treloar, Carla, Gray, Rebecca M, Argent, Angela, McGlaughlin, Ryan“…Qualitative feedback from participants and facilitators supported the acceptability of SMART Track and the need for improved integration into the SRAU groups. Participants reported significant reductions between the baseline and 8- week scores on the Severity of Dependence Scale (mean difference 1.93, SD 3.02; 95% CI 1.12-2.73) and the Kessler Psychological Distress Scale-10 (mean difference 3.96, SD 8.31; 95% CI 1.75-6.17), but no change on the Substance Use Recovery Evaluator (mean difference 0.11, SD 7.97; 95% CI –2.02 to 2.24) was reported. …”
Publicado 2021
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333586por Junior, FJ, Scharff, IC, Paulo, LD, Oliveira, AN, Zanella, CYS, Macêdo, RBF, Barbosa, CM, Mileo, MG, Almeida, GE, Scharff, IC, Scharff, IC“…A paciente foi encaminhada para Endoscopia Digestiva Alta e Ressonância Magnética de Coluna Lombossacra em sua alta da enfermaria Covid-19 para investigação etiológica DISCUSSÃO: Diante do contexto da Pandemia Covid-19, a investigação de sinais e sintomas clínicos não compatíveis com a infecção em uma internação, torna-se importante para o atendimento integral ao paciente, reconhecendo e investigando diagnósticos diferenciais que podem coexistir. …”
Publicado 2021
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333587“…WIDER IMPLICATIONS: Adenomyosis usually follows an event such as pregnancy that has disrupted the integrity of the endometrial–myometrial junction followed by repetitious menstrual episodes that increase the likelihood of the entrapment of the basalis endometrium within the myometrium. …”
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333588por Meyers, Michael“…This is the first longitudinal study to investigate the influence of a pad on sport trauma, when integrated with an artificial turf infill system.…”
Publicado 2021
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333589por Shea, Benjamin, Bakre, Shivani, Carano, Keaton, Scharen, Jared, Langheier, Jason, Hu, Emily A“…Less is known about the characteristics of people with diabetes who use digital health platforms (specifically, a platform that integrates personalized healthy meal plans and food ordering) and changes in their HbA(1c) levels. …”
Publicado 2021
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333590“…Conclusions: Exercise intervention increases the serum exosome level in MCAO rats, which are recruited into the brain, leading to improved synaptic growth and CST integrity, a reduced infarct volume, and improved neurological function and gait.…”
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333591por Loftus, Tyler J., Ruppert, Matthew M., Ozrazgat-Baslanti, Tezcan, Balch, Jeremy A., Efron, Philip A., Tighe, Patrick J., Hogan, William R., Rashidi, Parisa, Upchurch, Gilbert R., Bihorac, Azra“…DESIGN, SETTING, AND PARTICIPANTS: This longitudinal cross-sectional study was conducted using data from the University of Florida Integrated Data Repository on admissions to a university hospital. …”
Publicado 2021
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333592por Payne, Karl, Brooks, Jill M., Taylor, Graham S., Batis, Nikolaos, Noyvert, Boris, Pan, Yi, Nankivell, Paul, Mehanna, Hisham“…We aimed to evaluate the Parsortix microfluidic device for CTC enrichment and characterisation in HNSCC, seeking to optimise a sample collection and processing protocol that preserves CTC integrity and phenotype. Method: Spiking experiments of the FaDu and SCC040 HNSCC cell lines were used to determine the Parsortix capture rate of rare “CTC-like” cells. …”
Publicado 2021
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333593por Sprooten, Jenny, Vankerckhoven, Ann, Vanmeerbeek, Isaure, Borras, Daniel M, Berckmans, Yani, Wouters, Roxanne, Laureano, Raquel S, Baert, Thais, Boon, Louis, Landolfo, Chiara, Testa, Antonia Carla, Fischerova, Daniela, Van Holsbeke, Caroline, Bourne, Tom, Chiappa, Valentina, Froyman, Wouter, Schols, Dominique, Agostinis, Patrizia, Timmerman, Dirk, Tejpar, Sabine, Vergote, Ignace, Coosemans, An, Garg, Abhishek D“…METHODS: We used a data-driven in silico framework, integrating existing tumor/blood bulk-RNAseq or single-cell (sc)RNAseq datasets of patients with cancer, to inform the design of an innovative serum-screening modality, that is, serum-functional immunodynamic status (sFIS) assay. …”
Publicado 2021
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333594por Thompson, Peyton, Morgan, Camille E, Ngimbi, Patrick, Mwandagalirwa, Kashamuka, Ravelomanana, Noro L R, Tabala, Martine, Fathy, Malongo, Kawende, Bienvenu, Muwonga, Jérémie, Misingi, Pacifique, Mbendi, Charles, Luhata, Christophe, Jhaveri, Ravi, Cloherty, Gavin, Kaba, Didine, Yotebieng, Marcel, Parr, Jonathan B“…Birth-dose vaccination against HBV infection integrated within the current Expanded Programme on Immunisation and HIV prevention of mother-to-child transmission programme could accelerate progress toward HBV elimination in Africa.…”
Publicado 2021
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333595por Salloway, Stephen, Chalkias, Spyros, Barkhof, Frederik, Burkett, Patrick, Barakos, Jerome, Purcell, Derk, Suhy, Joyce, Forrestal, Fiona, Tian, Ying, Umans, Kimberly, Wang, Guanfang, Singhal, Priya, Budd Haeberlein, Samantha, Smirnakis, Karen“…CONCLUSIONS AND RELEVANCE: In this integrated safety data set from EMERGE and ENGAGE, the most common adverse event in the 10-mg/kg group was ARIA-E, which occurred in 362 of the 1029 patients (35.2%) in the 10-mg/kg group with at least 1 postbaseline MRI scan, with 94 patients (26.0%) experiencing associated symptoms. …”
Publicado 2021
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333596por Salle, V., Zerbib, Y., Maizel, J., Brault, C., Soudet, S., Andréjak, C., Diouf, M., Lanoix, J.P., Soriot-Thomas, S., Potriquier, S., Galmiche, A., Sevin, J., Herpe, Y.E., Slama, M.“…MATÉRIELS ET MÉTHODES: Il s’agit d’une étude prospective s’intégrant dans le cadre du protocole THROMBOCOVID. …”
Publicado 2021
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333597por Idrees, Atif, Qadir, Ziyad Abdul, Akutse, Komivi Senyo, Afzal, Ayesha, Hussain, Mubasher, Islam, Waqar, Waqas, Muhammad Saad, Bamisile, Bamisope Steve, Li, Jun“…These potent fungal isolates could be suitable candidates for developing biopesticides in an integrated manner to control the FAW population. By decreasing the hatchability of eggs and reducing the feeding ability of early first to third instar FAW larvae, the findings of this study could assist in managing this invasive pest in China and enhance maize crop output. …”
Publicado 2021
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333598por Bock, Andrew J, Sharma-Kuinkel, Batu K, Ruffin, Felicia, Mohnasky, Michael, Eichenberger, Emily, Maskarinec, Stacey, Fowler, Vance G, Thaden, Joshua“…Fowler, Jr., MD, MHS, Achaogen (Consultant)Advanced Liquid Logics (Grant/Research Support)Affinergy (Consultant, Grant/Research Support)Affinium (Consultant)Akagera (Consultant)Allergan (Grant/Research Support)Amphliphi Biosciences (Consultant)Aridis (Consultant)Armata (Consultant)Basilea (Consultant, Grant/Research Support)Bayer (Consultant)C3J (Consultant)Cerexa (Consultant, Other Financial or Material Support, Educational fees)Contrafect (Consultant, Grant/Research Support)Debiopharm (Consultant, Other Financial or Material Support, Educational fees)Destiny (Consultant)Durata (Consultant, Other Financial or Material Support, educational fees)Genentech (Consultant, Grant/Research Support)Green Cross (Other Financial or Material Support, Educational fees)Integrated Biotherapeutics (Consultant)Janssen (Consultant, Grant/Research Support)Karius (Grant/Research Support)Locus (Grant/Research Support)Medical Biosurfaces (Grant/Research Support)Medicines Co. …”
Publicado 2021
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333599por Brown, Keith“…CRISPRclean workflow easily integrates into next generation sequencing projects [Image: see text] Schematic of the Jumpcode CRISPRclean protocol METHODS: CRISPRclean was applied to contrived infected tissue samples including human lung RNA spiked with serially diluted amounts of SARS-CoV-2 RNA and bacterial RNA. …”
Publicado 2021
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333600por Mahani, Amir, Arvidsson, Gustav, Sadeghi, Laia, Grandien, Alf, Wright, Anthony P. H.“…A generalized linear model approach allowed an integrated analysis of RNA sequencing data to identify regulated genes in relation to both progressively increasing MYC level and wild type or mutant status. …”
Publicado 2021
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