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4941“…CONCLUSIONS: We propose a method (gBPCR) for the estimation of both LOH and CN aberrations, improving their estimation by integrating both types of data and accounting for their relationships. …”
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4942
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4943por Marsteller, Pat, de Pillis, Lisette, Findley, Ann, Joplin, Karl, Pelesko, John, Nelson, Karen, Thompson, Katerina, Usher, David, Watkins, Joseph“…In response to the call of BIO2010 for integrating quantitative skills into undergraduate biology education, 30 Howard Hughes Medical Institute (HHMI) Program Directors at the 2006 HHMI Program Directors Meeting established a consortium to investigate, implement, develop, and disseminate best practices resulting from the integration of math and biology. …”
Publicado 2010
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4944
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4945por Safran, Marilyn, Dalah, Irina, Alexander, Justin, Rosen, Naomi, Iny Stein, Tsippi, Shmoish, Michael, Nativ, Noam, Bahir, Iris, Doniger, Tirza, Krug, Hagit, Sirota-Madi, Alexandra, Olender, Tsviya, Golan, Yaron, Stelzer, Gil, Harel, Arye, Lancet, Doron“…Data enhancements include an expanded visualization of gene expression patterns in normal and cancer tissues, an integrated alternative splicing pattern display, and augmented multi-source SNPs and pathways sections. …”
Publicado 2010
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4946“…BACKGROUND: In response to concerns that the needs of the aging population for well-integrated care were increasing, the English National Health Service (NHS) appointed 16 Integrated Care Pilots following a national competition. …”
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4947
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4948
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4949
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4950
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4951
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4952
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4953
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4954“…Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cDNA within host chromosomal DNA. …”
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4955por Porter, Jason A., Wolbach, Kevin C., Purzycki, Catherine B., Bowman, Leslie A., Agbada, Eva, Mostrom, Alison M.“…Congruent with this goal, the Departments of Biological Sciences and Information Science developed an integrated IL and scientific literacy (SL) exercise for use in a first-year biology course. …”
Publicado 2010
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4956por Mühlberger, Irmgard, Moenks, Konrad, Bernthaler, Andreas, Jandrasits, Christine, Mayer, Bernd, Mayer, Gert, Oberbauer, Rainer, Perco, Paul“…Next to well established molecular features associated with the renin-angiotensin system numerous proteins involved in signal transduction and cell communication were found, involving specific molecular functions covering receptor binding with natriuretic peptide receptor and ligands as well known example. An integrated analysis of identified features pinpointed a protein interaction network involving mediators of hemodynamic change and an accumulation of features associated with the endothelin and VEGF signaling pathway. …”
Publicado 2010
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4957
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4958“…The goal of this review is to use a case-based approach to provide practical information about how integrated care using the CCM can be applied to the clinical care of a complex patient with COPD, shifting the management goals for COPD from reactive to proactive and ultimately improving outcomes.…”
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4959por Li, Peter, Dada, Joseph O, Jameson, Daniel, Spasic, Irena, Swainston, Neil, Carroll, Kathleen, Dunn, Warwick, Khan, Farid, Malys, Naglis, Messiha, Hanan L, Simeonidis, Evangelos, Weichart, Dieter, Winder, Catherine, Wishart, Jill, Broomhead, David S, Goble, Carole A, Gaskell, Simon J, Kell, Douglas B, Westerhoff, Hans V, Mendes, Pedro, Paton, Norman W“…Automating the assembly and use of systems biology models is dependent upon data integration processes involving the interoperation of data and analytical resources. …”
Publicado 2010
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4960“…For example, DNA rigidity can prevent nucleosome packaging, thereby making TFBSs in the rigid DNA regions more accessible to TFs. Integrating nucleosome occupancy, DNA bendability, TF binding, TF knockout expression and TFBS data helps to identify which TFBS is actually functional. …”
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