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7381por Kottmann, Renzo, Kostadinov, Ivalyo, Duhaime, Melissa Beth, Buttigieg, Pier Luigi, Yilmaz, Pelin, Hankeln, Wolfgang, Waldmann, Jost, Glöckner, Frank Oliver“…Megx.net is a database and portal that provides integrated access to georeferenced marker genes, environment data and marine genome and metagenome projects for microbial ecological genomics. …”
Publicado 2010
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7382por Markowitz, Victor M., Chen, I-Min A., Palaniappan, Krishna, Chu, Ken, Szeto, Ernest, Grechkin, Yuri, Ratner, Anna, Anderson, Iain, Lykidis, Athanasios, Mavromatis, Konstantinos, Ivanova, Natalia N., Kyrpides, Nikos C.“…The integrated microbial genomes (IMG) system serves as a community resource for comparative analysis of publicly available genomes in a comprehensive integrated context. …”
Publicado 2010
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7383por Wang, Lishan, Xiong, Yuanyuan, Sun, Yihua, Fang, Zhaoyuan, Li, Li, Ji, Hongbin, Shi, Tieliu“…The human lung cancer database (HLungDB) is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information. …”
Publicado 2010
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7384
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7385“…However, it has also been observed that integrating more data sources does not always increase the prediction quality. …”
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7386por Beck, Andrew H, Lee, Cheng-Han, Witten, Daniela M, Gleason, Briana C, Edris, Badreddin, Espinosa, Inigo, Zhu, Shirley, Li, Rui, Montgomery, Kelli D, Marinelli, Robert J, Tibshirani, Robert, Hastie, Trevor, Jablons, David M, Rubin, Brian P, Fletcher, Christopher D, West, Robert B, van de Rijn, Matt“…Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We employed integrative molecular profiling to discover and characterize molecular subtypes of LMS. …”
Publicado 2009
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7387por Shinde, Kaustubh, Phatak, Mukta, Johannes, Freudenberg M, Chen, Jing, Li, Qian, Vineet, Joshi K, Hu, Zhen, Ghosh, Krishnendu, Meller, Jaroslaw, Medvedovic, Mario“…RESULTS: Genomics Portals platform integrates access to an extensive knowledge base and a large database of human, mouse, and rat genomics data with basic analytical visualization tools. …”
Publicado 2010
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7388por Waterman, Claire L, Currie, Richard A, Cottrell, Lisa A, Dow, Jacky, Wright, Jayne, Waterfield, Catherine J, Griffin, Julian L“…Both metabolomics and transcriptomics detected changes in the liver which were dose dependent, even after one day of exposure. Integration of the two datasets associated perturbations with specific pathways. …”
Publicado 2010
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7389por Clark, Luke“…The psychobiological approach has examined case-control differences between groups of pathological gamblers and healthy controls, and has identified dysregulation of brain areas linked to reward and emotion, including the ventromedial prefrontal cortex (vmPFC) and striatum, as well as alterations in dopamine neurotransmission. In integrating these two approaches, recent data are discussed that reveal anomalous recruitment of the brain reward system (including the vmPFC and ventral striatum) during two common cognitive distortions in gambling games: the near-miss effect and the effect of personal control. …”
Publicado 2010
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7390por Piipari, Matias, Down, Thomas A., Saini, Harpreet, Enright, Anton, Hubbard, Tim J.P.“…The application includes a bundled and graphically integrated version of the NestedMICA motif inference suite that has no outside dependencies. …”
Publicado 2010
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7391por Choi, Jaeyoung, Park, Jongsun, Kim, Donghan, Jung, Kyongyong, Kang, Seogchan, Lee, Yong-Hwan“…CONCLUSIONS: The FSD can serve as an integrated platform supporting researches on secretory proteins in the fungal kingdom. …”
Publicado 2010
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7392por Tucker, Joseph D, Yang, Li-Gang, Zhu, Zheng-Jun, Yang, Bin, Yin, Yue-Pin, Cohen, Myron S, Chen, Xiang-Sheng“…CONCLUSION: These STI case studies reveal the potential for expanding integrated syphilis/HIV services at public STI clinics in China. …”
Publicado 2010
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7393“…RESULTS: We present Lists2Networks, a web-based system that allows users to upload lists of mammalian genes/proteins onto a server-based program for integrated analysis. The system includes web-based tools to manipulate lists with different set operations, to expand lists using existing mammalian networks of protein-protein interactions, co-expression correlation, or background knowledge co-annotation correlation, as well as to apply gene-list enrichment analyses against many gene-list libraries of prior biological knowledge such as pathways, gene ontology terms, kinase-substrate, microRNA-mRAN, and protein-protein interactions, metabolites, and protein domains. …”
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7394“…RESULTS: In this study, we integrated different kinds of omics data and developed a systematic method to construct the integrated cellular network based on coupling dynamic models and statistical assessments. …”
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7395“…Furthermore, the selected genes were found to be of high relevance and can be considered as potential biomarkers for the prognostic selection of cancer therapy. Availability: Integrative ME is implemented in the R package integrativeME (http://cran.r-project.org/). …”
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7396
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7397
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7398“…BACKGROUND: There is increasing global interest in regional palliative care networks (PCN) to integrate care, creating systems that are more cost-effective and responsive in multi-agency settings. …”
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7400