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  1. 7481
    “…The identification of genome-wide cis-regulatory modules (CRMs) and characterization of their associated epigenetic features are fundamental steps toward the understanding of gene regulatory networks. Although integrative analysis of available genome-wide information can provide new biological insights, the lack of novel methodologies has become a major bottleneck. …”
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    Decoding the genome with an integrative analysis tool: Combinatorial CRM Decoder
  2. 7482
    por Yamashita, Tadashi
    Publicado 2011
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    Glycosphingolipid Modification: Structural Diversity, Functional and Mechanistic Integration of Diabetes
  3. 7483
    “…We review both behavioral and neuroscience perspectives on cognitive aging, and then connect the findings in the two areas. From this integration, we suggest important unresolved questions and directions for future research.…”
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    Cerebral aging: integration of brain and behavioral models of cognitive function
  4. 7484
    por Bruijnzeels, Marc
    Publicado 2011
    “…AIMS: Develop a conceptual model to be able to systematically arrange empirical evidence on the effects of different types of organizations of integrated (primary) care. METHODS: During an expert meeting of directors of health centres we identified essential elements which they consider important for integrated primary care. …”
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    Research of organization of integrated primary care: a conceptual model
  5. 7485
    por Viktoria Stein, K
    Publicado 2011
    “…PURPOSE: Exploring the indicators most crucial for actors in health and social care services and identifying those which lead up to the initiation and implementation of integrated care. By analysing the reasons why integrated care is chosen and initiated, the underlying mechanisms and decision-making processes of integrated care are highlighted. …”
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    Why integrated care? Conclusions from an international expert survey
  6. 7486
    por Takahashi, Nobuaki, Mori, Yasuo
    Publicado 2011
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    TRP Channels as Sensors and Signal Integrators of Redox Status Changes
  7. 7487
    “…In terms of critical engagement, having integrated and qualitative social science components in the protocol meant potentially nesting alternative epistemologies at the heart of the randomized controlled trial. …”
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    Critically engaging: integrating the social and the biomedical in international microbicides research
  8. 7488
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    Juvenile idiopathic arthritis (JIA): can an integrated medicine be possible?
  9. 7489
    “…We determined the effect of FoxO6 on hepatic gluconeogenesis in genetically modified mice with FoxO6 gain- versus loss-of-function and in diabetic db/db mice with selective FoxO6 ablation in the liver. RESULTS: FoxO6 integrates insulin signaling to hepatic gluconeogenesis. …”
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    FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver
  10. 7490
    “…To fully appreciate this complexity, integrated knowledge about the human and the vector population is desirable. …”
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    Towards an integrated approach in surveillance of vector-borne diseases in Europe
  11. 7491
    “…RNA-Seq studies highlight a mRNA repertoire that suggests a previously unrecognized integrative role for the erythrocytes in other physiological systems.…”
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    RNA-Seq Reveals an Integrated Immune Response in Nucleated Erythrocytes
  12. 7492
    “…Viral integration hot-spots or 'common insertion sites' (CIS) are scrutinized to evaluate and predict patient safety. …”
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    Methodology and software to detect viral integration site hot-spots
  13. 7493
    “…Successful TB, HIV, and syphilis integrated testing programs in high risk populations will likely require one-visit diagnostic testing and incentives.…”
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    Feasibility and willingness-to-pay for integrated community-based tuberculosis testing
  14. 7494
    por Bousquet, Jean, Anto, Josep M, Sterk, Peter J, Adcock, Ian M, Chung, Kian Fan, Roca, Josep, Agusti, Alvar, Brightling, Chris, Cambon-Thomsen, Anne, Cesario, Alfredo, Abdelhak, Sonia, Antonarakis, Stylianos E, Avignon, Antoine, Ballabio, Andrea, Baraldi, Eugenio, Baranov, Alexander, Bieber, Thomas, Bockaert, Joël, Brahmachari, Samir, Brambilla, Christian, Bringer, Jacques, Dauzat, Michel, Ernberg, Ingemar, Fabbri, Leonardo, Froguel, Philippe, Galas, David, Gojobori, Takashi, Hunter, Peter, Jorgensen, Christian, Kauffmann, Francine, Kourilsky, Philippe, Kowalski, Marek L, Lancet, Doron, Pen, Claude Le, Mallet, Jacques, Mayosi, Bongani, Mercier, Jacques, Metspalu, Andres, Nadeau, Joseph H, Ninot, Grégory, Noble, Denis, Öztürk, Mehmet, Palkonen, Susanna, Préfaut, Christian, Rabe, Klaus, Renard, Eric, Roberts, Richard G, Samolinski, Boleslav, Schünemann, Holger J, Simon, Hans-Uwe, Soares, Marcelo Bento, Superti-Furga, Giulio, Tegner, Jesper, Verjovski-Almeida, Sergio, Wellstead, Peter, Wolkenhauer, Olaf, Wouters, Emiel, Balling, Rudi, Brookes, Anthony J, Charron, Dominique, Pison, Christophe, Chen, Zhu, Hood, Leroy, Auffray, Charles
    Publicado 2011
    “…This proposed holistic strategy involves comprehensive patient-centered integrated care and multi-scale, multi-modal and multi-level systems approaches to tackle NCDs as a common group of diseases. …”
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    Systems medicine and integrated care to combat chronic noncommunicable diseases
  15. 7495
    por Quester, Susanne, Schomburg, Dietmar
    Publicado 2011
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    EnzymeDetector: an integrated enzyme function prediction tool and database
  16. 7496
    “…BACKGROUND: This paper presents a framework for integrating disparate data sets to predict gene function. …”
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    Integrating phenotype and gene expression data for predicting gene function
  17. 7497
    “…The mutations either destabilize the integrated conformation or alter the TM1 ER integration profile. …”
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    Alteration of CFTR transmembrane span integration by disease-causing mutations
  18. 7498
    por Xu, Yue, Pan, Hong-Bin
    Publicado 2011
    “…An improved equivalent simulation model for a CMOS-integrated Hall plate is described in this paper. Compared with existing models, this model covers voltage dependent non-linear effects, geometrical effects, temperature effects and packaging stress influences, and only includes a small number of physical and technological parameters. …”
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    An Improved Equivalent Simulation Model for CMOS Integrated Hall Plates
  19. 7499
    “…We describe the design, fabrication and packaging of μGC on monolithically-integrated Si dies, comprised of a preconcentrator (PC), μGC column, detector and coatings for each of these components. …”
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    A Monolithically-Integrated μGC Chemical Sensor System
  20. 7500
    “…In this paper, we present the experimental measurements of our system which mimic the four most prominent biological cells: fast spiking, regular spiking, intrinsically bursting, and low-threshold spiking neurons into analog neuromimetic integrated circuit dedicated to cortical neuron simulations. …”
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    Tunable Neuromimetic Integrated System for Emulating Cortical Neuron Models
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